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The map label for this gene is aroB [H]

Identifier: 220930902

GI number: 220930902

Start: 60224

End: 61141

Strand: Direct

Name: aroB [H]

Synonym: Hore_00540

Alternate gene names: 220930902

Gene position: 60224-61141 (Clockwise)

Preceding gene: 220930901

Following gene: 220930903

Centisome position: 2.34

GC content: 39.65

Gene sequence:

>918_bases
ATGATGAAAGTCGGGGCTATTGATGTAGGCACTAATTCCTGCCGTATGTTAGCAGTAGAGCAATACGGTGATAAGTTAGA
AGAAATATGTTTTGATTTAAAAACCACCAGACTGGGACAGGGTGTTGATGAAAAACGACTTTTGAATTATGATGCGGTGA
GGAGAACCCTGTATGCCATAGAATTTTTTGTAAATAAAATGGAGGGGCTGGGGGTTGAAAGGATCAGGATTGTAGGGACC
AGTGCTCTGAGGGATGTCAGGAATAGCAATATTCTGCTTGATGTTGTTAAAAGAAGGACAGGATATGAGCTCGAAGTAAT
CTCAGGAGTTGAAGAGGCCAGGTTAACCTATACTGGAGCCAGTTTTGATATTAATGGGAATGATTTTTTAATTATTGATA
TCGGGGGTGGGAGTACTGAATTTATCTGGCAACAACCCTCTGGACTTAGTTTTAAAAGTCTGGATATGGGAGCTGTAAGG
ATGACAGAAAGGTATATAAAAACCCCTGATAAACCTGTCGATAGCCAGGACCTTGCCCGGATTAAAGAAGTAATTAACAG
GATGCTCAAGGGAAAGTTGAAGTTAAATCCTGCCGGAATAAATGTTATTGGAGTAGGTGGTACTATAACAACCCTGGCTG
CTATTGATTTAAAAATGAAAAAATATGACCGGGATAAAGTACATGGTTATAAAATAACCCGGGATAAAATAGAAGAGATT
TTGTTGAGGCTGGCAGGAAAAACTCTGGAAGAAAGGCGTAAGATAGTTGGACTTCAGCCGGAACGGGCTGATATAATAGT
GGCCGGGACTATTATTGCTTTAGCAATTATCGATTATCTGGCTCTTGACCACATTACCGTCAGTGAACACGATATTTTAT
ATGGATTGATAAAAGAAATGCTTGACTTAAGCCATTAA

Upstream 100 bases:

>100_bases
CTGATTATCTGGTTAACGGGGTTAATCCTGTAGGTAGACTGGTCTGGGAGAAACTTGACTGGCCTGAAAGGTGTAATCTC
TGCAGAATGGAGGCTGGTGA

Downstream 100 bases:

>100_bases
TTATATTATAATATTTCTGTCAGTTGAACAGGCCGGGGTGGCGGAACTGGCAGACGCATCGGACTTAAAATCCGGTGGGC
GTTTTCGCCCGTGTCGGTTC

Product: Exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MMKVGAIDVGTNSCRMLAVEQYGDKLEEICFDLKTTRLGQGVDEKRLLNYDAVRRTLYAIEFFVNKMEGLGVERIRIVGT
SALRDVRNSNILLDVVKRRTGYELEVISGVEEARLTYTGASFDINGNDFLIIDIGGGSTEFIWQQPSGLSFKSLDMGAVR
MTERYIKTPDKPVDSQDLARIKEVINRMLKGKLKLNPAGINVIGVGGTITTLAAIDLKMKKYDRDKVHGYKITRDKIEEI
LLRLAGKTLEERRKIVGLQPERADIIVAGTIIALAIIDYLALDHITVSEHDILYGLIKEMLDLSH

Sequences:

>Translated_305_residues
MMKVGAIDVGTNSCRMLAVEQYGDKLEEICFDLKTTRLGQGVDEKRLLNYDAVRRTLYAIEFFVNKMEGLGVERIRIVGT
SALRDVRNSNILLDVVKRRTGYELEVISGVEEARLTYTGASFDINGNDFLIIDIGGGSTEFIWQQPSGLSFKSLDMGAVR
MTERYIKTPDKPVDSQDLARIKEVINRMLKGKLKLNPAGINVIGVGGTITTLAAIDLKMKKYDRDKVHGYKITRDKIEEI
LLRLAGKTLEERRKIVGLQPERADIIVAGTIIALAIIDYLALDHITVSEHDILYGLIKEMLDLSH
>Mature_305_residues
MMKVGAIDVGTNSCRMLAVEQYGDKLEEICFDLKTTRLGQGVDEKRLLNYDAVRRTLYAIEFFVNKMEGLGVERIRIVGT
SALRDVRNSNILLDVVKRRTGYELEVISGVEEARLTYTGASFDINGNDFLIIDIGGGSTEFIWQQPSGLSFKSLDMGAVR
MTERYIKTPDKPVDSQDLARIKEVINRMLKGKLKLNPAGINVIGVGGTITTLAAIDLKMKKYDRDKVHGYKITRDKIEEI
LLRLAGKTLEERRKIVGLQPERADIIVAGTIIALAIIDYLALDHITVSEHDILYGLIKEMLDLSH

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=304, Percent_Identity=28.9473684210526, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788848, Length=307, Percent_Identity=28.3387622149837, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 34146; Mature: 34146

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKVGAIDVGTNSCRMLAVEQYGDKLEEICFDLKTTRLGQGVDEKRLLNYDAVRRTLYAI
CCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EFFVNKMEGLGVERIRIVGTSALRDVRNSNILLDVVKRRTGYELEVISGVEEARLTYTGA
HHHHHHHHCCCEEEEEEEEHHHHHHHCCCCCHHEEHHHCCCCEEEEECCCCHHEEEEECC
SFDINGNDFLIIDIGGGSTEFIWQQPSGLSFKSLDMGAVRMTERYIKTPDKPVDSQDLAR
EEEECCCEEEEEEECCCCCEEEEECCCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHHHH
IKEVINRMLKGKLKLNPAGINVIGVGGTITTLAAIDLKMKKYDRDKVHGYKITRDKIEEI
HHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHH
LLRLAGKTLEERRKIVGLQPERADIIVAGTIIALAIIDYLALDHITVSEHDILYGLIKEM
HHHHHCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHH
LDLSH
HHCCC
>Mature Secondary Structure
MMKVGAIDVGTNSCRMLAVEQYGDKLEEICFDLKTTRLGQGVDEKRLLNYDAVRRTLYAI
CCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EFFVNKMEGLGVERIRIVGTSALRDVRNSNILLDVVKRRTGYELEVISGVEEARLTYTGA
HHHHHHHHCCCEEEEEEEEHHHHHHHCCCCCHHEEHHHCCCCEEEEECCCCHHEEEEECC
SFDINGNDFLIIDIGGGSTEFIWQQPSGLSFKSLDMGAVRMTERYIKTPDKPVDSQDLAR
EEEECCCEEEEEEECCCCCEEEEECCCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHHHH
IKEVINRMLKGKLKLNPAGINVIGVGGTITTLAAIDLKMKKYDRDKVHGYKITRDKIEEI
HHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHH
LLRLAGKTLEERRKIVGLQPERADIIVAGTIIALAIIDYLALDHITVSEHDILYGLIKEM
HHHHHCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHH
LDLSH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]