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The map label for this gene is glnA [H]

Identifier: 220919487

GI number: 220919487

Start: 4905534

End: 4906958

Strand: Direct

Name: glnA [H]

Synonym: A2cp1_4408

Alternate gene names: 220919487

Gene position: 4905534-4906958 (Clockwise)

Preceding gene: 220919485

Following gene: 220919488

Centisome position: 97.54

GC content: 65.68

Gene sequence:

>1425_bases
ATGGCGAAACTCACCCCGAAGGCGGTCCTGGACCTGGCCAAGGAACGCAAGGCCACGTACGTGGACCTCAAGTTCATGGA
CTTCGTCGGGATCTGGCAGCACTTCTCGATCCCGCTCTACGAGCTCAGCGAGGAAGTGTTCGAGGCCGGCCTCGGCTTCG
ACGGCTCCTCGATCCGCGGCTGGCAGGCGATCCACGCCTCCGACATGCTCGTGGTCCCCGACGCGGACACGGCCGCGATC
GATCCGTTCATGGCGGAGCCGACGCTCTCGCTCATCTGCAACGTGGTCGATCCCATCACGAAGGAGCCGTACTCGCGCGA
CCCGCGCAACATCGCCATCAAGGCCGAGAAGTACCTCAAGTCCACCGGCCTCGGCGACACCGCGTTCTTCGGCCCCGAGC
CCGAGTTCTTCGTGTTCGACGAGGTCCGCTACGACCACGGCGTGAACCACGCGTTCTACAAGCTCGACTCGGTCGAGGGG
CAGTGGAACACCGGCCGCGAGGAGCCGGGTGGCAACCTCGGCTACAAGCCCCGCTACAAGGAGGGCTACTTCCCGGTCGG
CCCCACCGACTCGCAGCAGGACCTGCGCACCGAGATGTGCCGGGTGATGGAGTCGGTCGGCATCCACGTGGAGCGGCAGC
ACCACGAGGTCGCCACCGCCGGCCAGGCGGAGATCGACATCCGCTTCGACTCGCTGGTGAAGTGCGCCGACAACCTCCAG
TGGTTCAAGTACATCATCAAGAACGTGGCGCGCCGGCACGGCAAGACCGTGACCTTCATGCCGAAGCCGCTCTACGGCGA
CAACGGCTCCGGCATGCACGTGCACCAGTCGATCTGGAAGGCCGGCAAGCCGCTGTTCGCGGGCGACGGCTACGCGGGCC
TGTCCGAGATGGCGATGTACTACATCGGCGGCATCCTCAAGCACGGGCCGGCGCTGGCCGCGCTCTGCAACCCCTCCACG
AACAGCTACAAGCGGCTCGTGCCCGGGTTCGAGGCGCCGGTGAACCTGGCCTACTCGGCCCGCAACCGCTCCGCGTCGAT
CCGCATCCCGATGTACTCGCCGTCGCCCAAGGCGAAGCGCATCGAGTTCCGCTCGCCCGACCCGGCCTGCAACGGCTACC
TGGCGTTCGCGGCCATGCTGATGGCCGGCCTCGACGGCATCGAGAACAAGATCAACCCCGGCCAGCCGCTCGACAAGGAC
ATCTACGGCATGTCGCCGGAGGAGCTGAAGGACATCCCGAAGATGCCGGGCTCGCTCGACGAGGCGCTCGAGTGCCTCCG
CAAGGATCACAAGTTCCTGCTGAAGGGCGACGTCTTCACCGAGGACGTGATCGAGACCTGGATCCAGTACAAGTACGACA
AGGAGATCACCCCGGTCCGCATGCGCCCGAGCCCGATGGAGTTCGCGCTGTACTTCGACATCTAG

Upstream 100 bases:

>100_bases
AAAGATCCGCGGATCTGGGCGCGTCAGCGGCTCGCCGGCGTGGCATGAGCCGTGCTAACTGGGCCGGCCAACAACCCCGC
AGGCCGTGGAGATCCTCGCG

Downstream 100 bases:

>100_bases
GCGCGACCGAGGTCCCGCAGCACCGGGCGGCCGTCCGCGAGGGCGGCCGCCCTTCGATTATGTTGGGGGGCAGGAGGAGC
GCGCTCGTGCCCTGGATCTA

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MAKLTPKAVLDLAKERKATYVDLKFMDFVGIWQHFSIPLYELSEEVFEAGLGFDGSSIRGWQAIHASDMLVVPDADTAAI
DPFMAEPTLSLICNVVDPITKEPYSRDPRNIAIKAEKYLKSTGLGDTAFFGPEPEFFVFDEVRYDHGVNHAFYKLDSVEG
QWNTGREEPGGNLGYKPRYKEGYFPVGPTDSQQDLRTEMCRVMESVGIHVERQHHEVATAGQAEIDIRFDSLVKCADNLQ
WFKYIIKNVARRHGKTVTFMPKPLYGDNGSGMHVHQSIWKAGKPLFAGDGYAGLSEMAMYYIGGILKHGPALAALCNPST
NSYKRLVPGFEAPVNLAYSARNRSASIRIPMYSPSPKAKRIEFRSPDPACNGYLAFAAMLMAGLDGIENKINPGQPLDKD
IYGMSPEELKDIPKMPGSLDEALECLRKDHKFLLKGDVFTEDVIETWIQYKYDKEITPVRMRPSPMEFALYFDI

Sequences:

>Translated_474_residues
MAKLTPKAVLDLAKERKATYVDLKFMDFVGIWQHFSIPLYELSEEVFEAGLGFDGSSIRGWQAIHASDMLVVPDADTAAI
DPFMAEPTLSLICNVVDPITKEPYSRDPRNIAIKAEKYLKSTGLGDTAFFGPEPEFFVFDEVRYDHGVNHAFYKLDSVEG
QWNTGREEPGGNLGYKPRYKEGYFPVGPTDSQQDLRTEMCRVMESVGIHVERQHHEVATAGQAEIDIRFDSLVKCADNLQ
WFKYIIKNVARRHGKTVTFMPKPLYGDNGSGMHVHQSIWKAGKPLFAGDGYAGLSEMAMYYIGGILKHGPALAALCNPST
NSYKRLVPGFEAPVNLAYSARNRSASIRIPMYSPSPKAKRIEFRSPDPACNGYLAFAAMLMAGLDGIENKINPGQPLDKD
IYGMSPEELKDIPKMPGSLDEALECLRKDHKFLLKGDVFTEDVIETWIQYKYDKEITPVRMRPSPMEFALYFDI
>Mature_473_residues
AKLTPKAVLDLAKERKATYVDLKFMDFVGIWQHFSIPLYELSEEVFEAGLGFDGSSIRGWQAIHASDMLVVPDADTAAID
PFMAEPTLSLICNVVDPITKEPYSRDPRNIAIKAEKYLKSTGLGDTAFFGPEPEFFVFDEVRYDHGVNHAFYKLDSVEGQ
WNTGREEPGGNLGYKPRYKEGYFPVGPTDSQQDLRTEMCRVMESVGIHVERQHHEVATAGQAEIDIRFDSLVKCADNLQW
FKYIIKNVARRHGKTVTFMPKPLYGDNGSGMHVHQSIWKAGKPLFAGDGYAGLSEMAMYYIGGILKHGPALAALCNPSTN
SYKRLVPGFEAPVNLAYSARNRSASIRIPMYSPSPKAKRIEFRSPDPACNGYLAFAAMLMAGLDGIENKINPGQPLDKDI
YGMSPEELKDIPKMPGSLDEALECLRKDHKFLLKGDVFTEDVIETWIQYKYDKEITPVRMRPSPMEFALYFDI

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=400, Percent_Identity=22.75, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI1790301, Length=471, Percent_Identity=56.0509554140127, Blast_Score=560, Evalue=1e-160,
Organism=Escherichia coli, GI87081870, Length=441, Percent_Identity=24.7165532879819, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53213; Mature: 53082

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTPKAVLDLAKERKATYVDLKFMDFVGIWQHFSIPLYELSEEVFEAGLGFDGSSIRG
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
WQAIHASDMLVVPDADTAAIDPFMAEPTLSLICNVVDPITKEPYSRDPRNIAIKAEKYLK
EEEECCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH
STGLGDTAFFGPEPEFFVFDEVRYDHGVNHAFYKLDSVEGQWNTGREEPGGNLGYKPRYK
HCCCCCCCCCCCCCCEEEEEEEHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
EGYFPVGPTDSQQDLRTEMCRVMESVGIHVERQHHEVATAGQAEIDIRFDSLVKCADNLQ
CCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHCCCCCEEEEEHHHHHHHHHHHH
WFKYIIKNVARRHGKTVTFMPKPLYGDNGSGMHVHQSIWKAGKPLFAGDGYAGLSEMAMY
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCHHHHHHH
YIGGILKHGPALAALCNPSTNSYKRLVPGFEAPVNLAYSARNRSASIRIPMYSPSPKAKR
HHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCE
IEFRSPDPACNGYLAFAAMLMAGLDGIENKINPGQPLDKDIYGMSPEELKDIPKMPGSLD
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHCCCCCCHH
EALECLRKDHKFLLKGDVFTEDVIETWIQYKYDKEITPVRMRPSPMEFALYFDI
HHHHHHHHCCCEEEECCCHHHHHHHHHHHEECCCCCCCEEECCCCCEEEEEEEC
>Mature Secondary Structure 
AKLTPKAVLDLAKERKATYVDLKFMDFVGIWQHFSIPLYELSEEVFEAGLGFDGSSIRG
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
WQAIHASDMLVVPDADTAAIDPFMAEPTLSLICNVVDPITKEPYSRDPRNIAIKAEKYLK
EEEECCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH
STGLGDTAFFGPEPEFFVFDEVRYDHGVNHAFYKLDSVEGQWNTGREEPGGNLGYKPRYK
HCCCCCCCCCCCCCCEEEEEEEHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
EGYFPVGPTDSQQDLRTEMCRVMESVGIHVERQHHEVATAGQAEIDIRFDSLVKCADNLQ
CCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHCCCCCEEEEEHHHHHHHHHHHH
WFKYIIKNVARRHGKTVTFMPKPLYGDNGSGMHVHQSIWKAGKPLFAGDGYAGLSEMAMY
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCHHHHHHH
YIGGILKHGPALAALCNPSTNSYKRLVPGFEAPVNLAYSARNRSASIRIPMYSPSPKAKR
HHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCE
IEFRSPDPACNGYLAFAAMLMAGLDGIENKINPGQPLDKDIYGMSPEELKDIPKMPGSLD
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHCCCCCCHH
EALECLRKDHKFLLKGDVFTEDVIETWIQYKYDKEITPVRMRPSPMEFALYFDI
HHHHHHHHCCCEEEECCCHHHHHHHHHHHEECCCCCCCEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7727755; 8905231 [H]