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The map label for this gene is atoS [H]

Identifier: 220919484

GI number: 220919484

Start: 4901998

End: 4903089

Strand: Direct

Name: atoS [H]

Synonym: A2cp1_4405

Alternate gene names: 220919484

Gene position: 4901998-4903089 (Clockwise)

Preceding gene: 220919483

Following gene: 220919485

Centisome position: 97.47

GC content: 76.92

Gene sequence:

>1092_bases
ATGCGCGCGGCGGCGGACCGGTCCACCGCACCCGTGTCCCGCACCGTCCAGCCCGCCCAGCTCTCCGCCGCGCTCTCCCG
CGCCGCGATCGACTCCCTCGCCGACGCGGTCGTGATCGTCGGCGCGGACGGCGGGGTGCTGCACCTCAACCCCGCCGCCG
AGGAGCTGTTCGGCCGCTCGCGCGAGCGGACGGTGGAGCTGCCGGTGCGGGCGCTCCCGGGCGGCGCCCAGCTCGAGAAG
GTGGCCGAGCGGACGGTGCGGACGCACGAGGGCCAGGCGAGCGAGTTTCCTTCGCCGCAGGACCGCGCGCTCCAGGTCTC
GGTCACCGCCACCCCGCTCCTCGACGGCGCGGTGTGCGCCGGGGCGGTGCTGGTGCTGCGGGTGCCGCGCTCCGCCGAGC
GCGCGCTCGACTTCGAGGCGCTCGCGGCCGGCCTCGCCCACGAGATCAAGAACCCGCTGGCCGGGCTGCAGGGCTCGGCC
GAGCTGCTCGCCCGCGAGGCCGAGGGGCCGGCCCGCGAGTACGCCGCGGTGATCGCGCGCGAGGCGAAGCGCGTGGACGG
GCTGGTGCGCGAGCTCCTCGACCTCGCCCGCCCGGCGGCGCTGCAGCAGGGGCCGGTCGCGCTCCACGACGTGCTCGGCG
ACGCGCTGGTGCTGGCGCGCGGCATCCCCGGCGCCGACCGGATCGCGTTCGTGGAGCGCTACGACCCGTCGCTCCCGCCG
GTGCTGGGCGACGAGGAGAAGCTGATGCAGGTGGTGCTGAACCTCGTCCGCAACGCGGTGGACGCGGTCGCCTCCACCGC
CGCGCCGCGGGTGACCATCGAGACCTCGGTGTCCCCGCTGCGCCTCCGCGTGGCGAGCGGCCGCACCCGCCCGCTGGCGC
GCATCTCGATCCAGGACGAGGGCCCGGGGATCCCCGAGGCCATGCTGCAGCGGCTGTTCACGCCCTTCGCGACCTCGAAG
CCGCACGGCACCGGCCTCGGGCTCGCCATCTCGCGGCGCATCGTGGAGGCGCACGGCGGGCGCATCGAGGTGCGCAACCG
GGCCGGCGGCGGGGCCGAGGCGAACGTGTACCTGCCCCTCGACGTCCCCTAG

Upstream 100 bases:

>100_bases
CCGGCGAGCGCGGGGAGGAGGCGCTCTAGCGCCTCGTCGTCCGCGCGTGCGGACGCCCTCCCGCGTCCGCCGCCGGACGG
CCCCATCGCCCGCCGCCCGC

Downstream 100 bases:

>100_bases
CCCGTCCGGCGTAGCGCCGGCGCCGCGGGCCCCGCGCTTGCCGGCGCGAGTTGGCCCCGCGCTTGCTATGAGGTACCGGG
ATCGGCGGATCATCACGGGA

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRAAADRSTAPVSRTVQPAQLSAALSRAAIDSLADAVVIVGADGGVLHLNPAAEELFGRSRERTVELPVRALPGGAQLEK
VAERTVRTHEGQASEFPSPQDRALQVSVTATPLLDGAVCAGAVLVLRVPRSAERALDFEALAAGLAHEIKNPLAGLQGSA
ELLAREAEGPAREYAAVIAREAKRVDGLVRELLDLARPAALQQGPVALHDVLGDALVLARGIPGADRIAFVERYDPSLPP
VLGDEEKLMQVVLNLVRNAVDAVASTAAPRVTIETSVSPLRLRVASGRTRPLARISIQDEGPGIPEAMLQRLFTPFATSK
PHGTGLGLAISRRIVEAHGGRIEVRNRAGGGAEANVYLPLDVP

Sequences:

>Translated_363_residues
MRAAADRSTAPVSRTVQPAQLSAALSRAAIDSLADAVVIVGADGGVLHLNPAAEELFGRSRERTVELPVRALPGGAQLEK
VAERTVRTHEGQASEFPSPQDRALQVSVTATPLLDGAVCAGAVLVLRVPRSAERALDFEALAAGLAHEIKNPLAGLQGSA
ELLAREAEGPAREYAAVIAREAKRVDGLVRELLDLARPAALQQGPVALHDVLGDALVLARGIPGADRIAFVERYDPSLPP
VLGDEEKLMQVVLNLVRNAVDAVASTAAPRVTIETSVSPLRLRVASGRTRPLARISIQDEGPGIPEAMLQRLFTPFATSK
PHGTGLGLAISRRIVEAHGGRIEVRNRAGGGAEANVYLPLDVP
>Mature_363_residues
MRAAADRSTAPVSRTVQPAQLSAALSRAAIDSLADAVVIVGADGGVLHLNPAAEELFGRSRERTVELPVRALPGGAQLEK
VAERTVRTHEGQASEFPSPQDRALQVSVTATPLLDGAVCAGAVLVLRVPRSAERALDFEALAAGLAHEIKNPLAGLQGSA
ELLAREAEGPAREYAAVIAREAKRVDGLVRELLDLARPAALQQGPVALHDVLGDALVLARGIPGADRIAFVERYDPSLPP
VLGDEEKLMQVVLNLVRNAVDAVASTAAPRVTIETSVSPLRLRVASGRTRPLARISIQDEGPGIPEAMLQRLFTPFATSK
PHGTGLGLAISRRIVEAHGGRIEVRNRAGGGAEANVYLPLDVP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=365, Percent_Identity=31.5068493150685, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790300, Length=346, Percent_Identity=31.5028901734104, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=34.8936170212766, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786600, Length=353, Percent_Identity=25.7790368271955, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=32.3651452282158, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=366, Percent_Identity=26.2295081967213, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=29.6137339055794, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=27.1551724137931, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=26.1802575107296, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=28.3261802575107, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=26.5822784810127, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38100; Mature: 38100

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAADRSTAPVSRTVQPAQLSAALSRAAIDSLADAVVIVGADGGVLHLNPAAEELFGRS
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHHCCC
RERTVELPVRALPGGAQLEKVAERTVRTHEGQASEFPSPQDRALQVSVTATPLLDGAVCA
CCCEEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHH
GAVLVLRVPRSAERALDFEALAAGLAHEIKNPLAGLQGSAELLAREAEGPAREYAAVIAR
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHH
EAKRVDGLVRELLDLARPAALQQGPVALHDVLGDALVLARGIPGADRIAFVERYDPSLPP
HHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEEEHHHCCCCCCC
VLGDEEKLMQVVLNLVRNAVDAVASTAAPRVTIETSVSPLRLRVASGRTRPLARISIQDE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCC
GPGIPEAMLQRLFTPFATSKPHGTGLGLAISRRIVEAHGGRIEVRNRAGGGAEANVYLPL
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEE
DVP
CCC
>Mature Secondary Structure
MRAAADRSTAPVSRTVQPAQLSAALSRAAIDSLADAVVIVGADGGVLHLNPAAEELFGRS
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHHCCC
RERTVELPVRALPGGAQLEKVAERTVRTHEGQASEFPSPQDRALQVSVTATPLLDGAVCA
CCCEEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHH
GAVLVLRVPRSAERALDFEALAAGLAHEIKNPLAGLQGSAELLAREAEGPAREYAAVIAR
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHH
EAKRVDGLVRELLDLARPAALQQGPVALHDVLGDALVLARGIPGADRIAFVERYDPSLPP
HHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEEEHHHCCCCCCC
VLGDEEKLMQVVLNLVRNAVDAVASTAAPRVTIETSVSPLRLRVASGRTRPLARISIQDE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCC
GPGIPEAMLQRLFTPFATSKPHGTGLGLAISRRIVEAHGGRIEVRNRAGGGAEANVYLPL
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEE
DVP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]