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The map label for this gene is trpD

Identifier: 220919276

GI number: 220919276

Start: 4683484

End: 4684497

Strand: Direct

Name: trpD

Synonym: A2cp1_4197

Alternate gene names: 220919276

Gene position: 4683484-4684497 (Clockwise)

Preceding gene: 220919275

Following gene: 220919277

Centisome position: 93.12

GC content: 75.74

Gene sequence:

>1014_bases
GTGATCCAGCAGGCCATCGCGAAGCTCCTGGAGGGCGAGGACCTCACCCGCGCCGAGGCGGCCCTGGTGATGACCGAGAT
CGCCGACGGCGGCGCCACCCCGGCCCAGTCGGGCGCGTTCCTGGCGGCGCTGCGCATGAAGGGCGAGACGGTGGACGAGA
TCGCCGGCGCCGCCGACGTGATGCGCCAGCGGGCGGACCGGGTGCGGGTGGATCGCGACGTGTTCATCGACACCTGCGGC
ACCGGCGGCGACGGGCGCCACACCTTCAACATCTCCACCACCGCCGCGTTCGTGGCGGCCGGCGCGGGCGTGTGCGTGGC
GAAGCACGGCAACCGCGCCGTGTCGTCGCGCTCCGGCTCCGCCGACGTGCTCGCCGCGCTGGGCGTGAACGTGGACGCGG
ACAAGGAGACGGTGGAGCGCTGCATCGAGGAGGTCGGCATCGGCTTCCTGTTCGCGGTGCGGCTCCACCCCGCGTTCAAG
GCCATCGCCGGCGTGCGCCGCGAGCTGGGCGTGCGCACCATCTTCAACCTGCTCGGCCCGCTCGCGAACCCCGCCGGCGC
GCGCCACCAGGTGCTCGGCGTGTACGAGGCGCGCTGGGTGCCGGTGCTGGGCGGCGTGCTGGCGGCGCTGGGCGCCGCGC
ACGCGTTCGTGGTGCACGGCGAGGGGCTGGACGAGATCGCCGTGACCGGCATGACGCACGTCTGCGAGGTGAGGGACGGC
CAGGTGGAGCGCTACACCATCCGGCCCGAGGACCTGGGGCTGCCGCGGCGCGACGCCGCCGAGCTCGTCGGCGGCGACGC
GGTGGCGAACGCCCGCATCGTCACCGACGTGCTGGAGGGACAGGCGGGCGGGCCGCGCGACGCGGTGCTGGCGAACGCCG
CCGCCGCGCTGGTGTGCGCCGGCGCCGCCAAGGACCTGCGCGACGGCGTGGCGCGCGCCGCCCGGTCCATCGACTCGGGC
GCCGCCCGCGAGAAGCTGCGGCAGCTGGTGGCCGCCACCACGGTGCCGGCGTGA

Upstream 100 bases:

>100_bases
GCGTGCAGTTCCACCCCGAGTCGATCCTGACGCTGGATGGCAAGCGCCTGCTCGGGAACTGGCTCGCGCACGTCGCGCCG
CGCGGCGAGGAGGCACGGCC

Downstream 100 bases:

>100_bases
CGGTCCTCGACGGCATCCTGGCCCGGAAGGTCGACGAGGTGGCCGCCCGCCGCGCGGCCGAACCCGACGCGGCGCTGGCC
GCGCGCGCCGCCGCCGCCCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIQQAIAKLLEGEDLTRAEAALVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADVMRQRADRVRVDRDVFIDTCG
TGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGSADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFK
AIAGVRRELGVRTIFNLLGPLANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDG
QVERYTIRPEDLGLPRRDAAELVGGDAVANARIVTDVLEGQAGGPRDAVLANAAAALVCAGAAKDLRDGVARAARSIDSG
AAREKLRQLVAATTVPA

Sequences:

>Translated_337_residues
MIQQAIAKLLEGEDLTRAEAALVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADVMRQRADRVRVDRDVFIDTCG
TGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGSADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFK
AIAGVRRELGVRTIFNLLGPLANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDG
QVERYTIRPEDLGLPRRDAAELVGGDAVANARIVTDVLEGQAGGPRDAVLANAAAALVCAGAAKDLRDGVARAARSIDSG
AAREKLRQLVAATTVPA
>Mature_337_residues
MIQQAIAKLLEGEDLTRAEAALVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADVMRQRADRVRVDRDVFIDTCG
TGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGSADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFK
AIAGVRRELGVRTIFNLLGPLANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDG
QVERYTIRPEDLGLPRRDAAELVGGDAVANARIVTDVLEGQAGGPRDAVLANAAAALVCAGAAKDLRDGVARAARSIDSG
AAREKLRQLVAATTVPA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=330, Percent_Identity=36.969696969697, Blast_Score=203, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=357, Percent_Identity=29.1316526610644, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ANAD2 (B8JAL5)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002494580.1
- ProteinModelPortal:   B8JAL5
- SMR:   B8JAL5
- GeneID:   7298301
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_4197
- HOGENOM:   HBG559996
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34807; Mature: 34807

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQQAIAKLLEGEDLTRAEAALVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADV
CHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHH
MRQRADRVRVDRDVFIDTCGTGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGS
HHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCHHCCCCCC
ADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFKAIAGVRRELGVRTIFNLLGP
HHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCHHHHEECCCC
QVERYTIRPEDLGLPRRDAAELVGGDAVANARIVTDVLEGQAGGPRDAVLANAAAALVCA
CEEEEEECHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GAAKDLRDGVARAARSIDSGAAREKLRQLVAATTVPA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQQAIAKLLEGEDLTRAEAALVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADV
CHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHH
MRQRADRVRVDRDVFIDTCGTGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGS
HHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCHHCCCCCC
ADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFKAIAGVRRELGVRTIFNLLGP
HHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCHHHHEECCCC
QVERYTIRPEDLGLPRRDAAELVGGDAVANARIVTDVLEGQAGGPRDAVLANAAAALVCA
CEEEEEECHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GAAKDLRDGVARAARSIDSGAAREKLRQLVAATTVPA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA