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The map label for this gene is panD

Identifier: 220919273

GI number: 220919273

Start: 4680876

End: 4681271

Strand: Direct

Name: panD

Synonym: A2cp1_4194

Alternate gene names: 220919273

Gene position: 4680876-4681271 (Clockwise)

Preceding gene: 220919272

Following gene: 220919274

Centisome position: 93.07

GC content: 66.67

Gene sequence:

>396_bases
ATGCGTCGGACCTTCTTCAAGGCGAAGATCCATCGTGCGACCGTGACGCACGCGGATCTCGAGTACGAGGGCTCGGTCTC
CATCGACGAGGACCTGCTCGAGGCCGCGGGCATCTGGGAGTACGAGGCCGTCCACATCTGGAACATCACCCGCGGCACCC
GGTTGCAGACGTACGCGATCAAGGGTGAGCGCGGCTCCGGCATCATCTGCATCAACGGCGCGGCCGCGCACCTCAACCGC
CCCGGCGACATGGTGATCCTCGCCACGTTCGCCGAGCTGGAAGAGGCCGAGGCTCGCGACTTCAAGCCCACCGTGGTCCT
CGTCGACCGCCAGAACAAGATCGTGGCCAAGGACGCCGTCGAGGTGCCCGGCCCGGCACGCAGGGTGACGGCATGA

Upstream 100 bases:

>100_bases
CTTCCACGACTGACCGCCGGCCCCCGCCATGCGGGGGGCCGGGCGGCGGGCGCGGGTGTTGCGCGAACCGACCCGACCAT
GTAAGAAAACGAGTCCTGCC

Downstream 100 bases:

>100_bases
CGGTGCGTCTTTGGCAAGTCCGCTGAGCTGCGGACCACCCCCGATCTCCAGACCTTCCTCTCCCTCTGCAGCCCCGGCCG
CGCGGTCCCGGTGCGCGTCG

Product: aspartate 1-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAIKGERGSGIICINGAAAHLNR
PGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAVEVPGPARRVTA

Sequences:

>Translated_131_residues
MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAIKGERGSGIICINGAAAHLNR
PGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAVEVPGPARRVTA
>Mature_131_residues
MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAIKGERGSGIICINGAAAHLNR
PGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAVEVPGPARRVTA

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=114, Percent_Identity=53.5087719298246, Blast_Score=130, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_ANAD2 (B8JAL2)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002494577.1
- ProteinModelPortal:   B8JAL2
- SMR:   B8JAL2
- GeneID:   7298298
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_4194
- HOGENOM:   HBG302821
- ProtClustDB:   CLSK947004
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14531; Mature: 14531

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAI
CCCCEEEEEEEEEEEEECCEEECCCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEEEEE
KGERGSGIICINGAAAHLNRPGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAV
ECCCCCEEEEECCCHHCCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCCCEEECCCC
EVPGPARRVTA
CCCCCCCCCCC
>Mature Secondary Structure
MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAI
CCCCEEEEEEEEEEEEECCEEECCCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEEEEE
KGERGSGIICINGAAAHLNRPGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAV
ECCCCCEEEEECCCHHCCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCCCEEECCCC
EVPGPARRVTA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA