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The map label for this gene is nhaA1 [H]

Identifier: 220919271

GI number: 220919271

Start: 4677941

End: 4679956

Strand: Direct

Name: nhaA1 [H]

Synonym: A2cp1_4192

Alternate gene names: 220919271

Gene position: 4677941-4679956 (Clockwise)

Preceding gene: 220919270

Following gene: 220919272

Centisome position: 93.01

GC content: 74.26

Gene sequence:

>2016_bases
ATGAAGCACGTGAGCTGGGTGGTCGCGCTCGTCATCGGGTTCGCGATCGGATTCGTCGGGCGCGGCTCGTGGGATGCGGG
CGGCCGGCCGTCCCGCGCGCCCGTGGGCGCGCCCACGCGCGCGCGTCCGGTGGAGGATCCGAAGGCCGTCTACCGGGTCC
CCGCGGACGACTCGCCGGTGCGCGGCCCGGCCGACGCGCTCGTCACCATCGTCGAGTCGTCCGACTTCCAGTGCCCGTAC
TGCAAGCGCGGCGCGGCCACCATGAAGCAGGTCGAGGAGGCGTACCGCGGCAAGGTGCGCTTCGTCTTCAAGCACAACCC
GCTCTCGTTCCACCCGCAGGCCATGCCGGCCGCGCTCGCCGCCGAGGAGGCGCGGGCGCAGGGCGGCGACGAGAAGTTCT
GGGCGCTGCACGACAAGCTGTTCGACTCGGCCCCCGCGCTCGACCAGGCCGCCATCGAGAAGGCCGCCGGCGAGCTCGGC
CTCGACGTCGCCAAGGTCCGCGAGGCGATGCAGGCCGGCACCCACCGCGCCCGCATCGAGCGCGACCAGAAGCTGGTGGT
CGGCCTGGGCGCACCGGCCACCCCGACGTTCTTCGTGAACGGGCGGAAGATCGCCGGCGCGCAGCCGATCGAGGCGTTCC
GCGCGGTGATCGACGAGGAGCTCGCCAGGGCCGAGCAGCTCGTCCGGTCCGGCACGCCGGCGTCGCAGGTCTATGCGAAG
GCCATCGAGCGCGGCGCGACCGCCCCGGTGTTCCTGCCCGGCACCGTGCCGCCCCCGACCGCCGCCGCGCCCTCGCCGGC
CGCCCCGGCGCCGGCGGCCCCCGCGGCCCCGCCGCCCGCCACCTACGCGAAGGTCCCGCTCCGCGCCGACGACCCGGCGC
GCGGCCCGGCGGACGCGAAGCTGACGGTGGTGCTGTTCTCCGACTTCCAGTGCCCGTTCTGCTCCCGCGTCGAGCCCACC
CTGAAGCAGCTCGAGCAGGCGTACCCGGGCCAGGTGCGGATCGTGTGGAAGCACCAGCCGCTCTCCTTCCACCCGAACGC
CATGCCGGCGGCCATCGCCGCCGAGGCGGCCCGCGAGCAGGGCAAGTTCTGGCCGATGCACGAGAAGCTGTTCTCGAACC
AGCAGGCGCTCTCCCCCGCGACCTACGAGCAGTACGCGAAGGAGCTCGGCCTCGACCTGCGCAAGTTCCAGGCGGCGGTG
GCGGCGCGCAAGGGCGCCGACCGGATCGCGGCCGATCAGCAGCTCGCCGGGTCGGTGGGCGCGAACGGCACGCCGACGAT
GTTCTTCAACTGCCGCCAGGTGGTGGGCGCGCTCCCGCTCGAGCGGATGCGCCCGGTGGTCGAGGAGGAGCTGAAGAAGG
CGGACGCGCTGCTGAAGGGCGGGAAGGCCGGCGCCGGGTTCTACGAGCAGGCCTGCCAGGCGAACCTGGCGCTGAAGCCG
GCCGCGCCGCAGCAGGGCGCGGTGGTCCCGGCGGCGCTGCCGGCCGGCCAGCCGGTGCAGGGCCTCGCGGTCCGCGCCGA
CGACCCGATCCGCGGCAACCCGAAGGCGCCGGTCACGATCGTGCTGTTCTCGGACTTCCAGTGCCCGTTCTGCGCCCGCG
TCGAGCCGACGCTCGCGCAGGTGCAGAAGACGTACGGCGACAAGGTCCGCGTGGTCTGGAAGCACCAGCCGCTCGGCATG
CACCCGAACGCGCTGCCCGCGGCCGAGGCCGCCGAGGCGGCCCGCGAGCAGGGCAAGTTCTGGCAGATGCACGAGAAGCT
GTTCGCGAGCCAGCGTGAGCTGTCCGACGCGCTGTACGAGCGGGCCGCCCGCGAGATCGGCCTCGACGTGGCCCGCTTCG
ACGCGGCCCGCCGCTCCGGCCGCGCCCGCACCCGCATCGCCGAGGACCAGGCGCTGGCCGCCCGCATCGGCGCGCAGGCC
ACGCCCACCATGTTCGTGAACGGCGTGAAGGTGGAAGGCGCGGTGCCGTTCGAGCAGATCCGCGCGGTCGTCGATGCCGA
GCTCGCGCGCCGCTAG

Upstream 100 bases:

>100_bases
GTTCGGCCTGGCGGCGCGGCGGGGGGCCGGCGCGTTGTCCACCCCGGGCGATCCTGATATCTGCGGTGGCTCTGACTTGG
CTGGAAGGGAGACGGGACAC

Downstream 100 bases:

>100_bases
CGGCCCCGCAGGTCCCGTGGCGTCGGGGGTGGGCGCGCCGGCGCCCGCCCCGCTCGCGCCCGCCGTCGCGGCCGCCTGGG
ATGCGCTCCACCGCGCGTTC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MKHVSWVVALVIGFAIGFVGRGSWDAGGRPSRAPVGAPTRARPVEDPKAVYRVPADDSPVRGPADALVTIVESSDFQCPY
CKRGAATMKQVEEAYRGKVRFVFKHNPLSFHPQAMPAALAAEEARAQGGDEKFWALHDKLFDSAPALDQAAIEKAAGELG
LDVAKVREAMQAGTHRARIERDQKLVVGLGAPATPTFFVNGRKIAGAQPIEAFRAVIDEELARAEQLVRSGTPASQVYAK
AIERGATAPVFLPGTVPPPTAAAPSPAAPAPAAPAAPPPATYAKVPLRADDPARGPADAKLTVVLFSDFQCPFCSRVEPT
LKQLEQAYPGQVRIVWKHQPLSFHPNAMPAAIAAEAAREQGKFWPMHEKLFSNQQALSPATYEQYAKELGLDLRKFQAAV
AARKGADRIAADQQLAGSVGANGTPTMFFNCRQVVGALPLERMRPVVEEELKKADALLKGGKAGAGFYEQACQANLALKP
AAPQQGAVVPAALPAGQPVQGLAVRADDPIRGNPKAPVTIVLFSDFQCPFCARVEPTLAQVQKTYGDKVRVVWKHQPLGM
HPNALPAAEAAEAAREQGKFWQMHEKLFASQRELSDALYERAAREIGLDVARFDAARRSGRARTRIAEDQALAARIGAQA
TPTMFVNGVKVEGAVPFEQIRAVVDAELARR

Sequences:

>Translated_671_residues
MKHVSWVVALVIGFAIGFVGRGSWDAGGRPSRAPVGAPTRARPVEDPKAVYRVPADDSPVRGPADALVTIVESSDFQCPY
CKRGAATMKQVEEAYRGKVRFVFKHNPLSFHPQAMPAALAAEEARAQGGDEKFWALHDKLFDSAPALDQAAIEKAAGELG
LDVAKVREAMQAGTHRARIERDQKLVVGLGAPATPTFFVNGRKIAGAQPIEAFRAVIDEELARAEQLVRSGTPASQVYAK
AIERGATAPVFLPGTVPPPTAAAPSPAAPAPAAPAAPPPATYAKVPLRADDPARGPADAKLTVVLFSDFQCPFCSRVEPT
LKQLEQAYPGQVRIVWKHQPLSFHPNAMPAAIAAEAAREQGKFWPMHEKLFSNQQALSPATYEQYAKELGLDLRKFQAAV
AARKGADRIAADQQLAGSVGANGTPTMFFNCRQVVGALPLERMRPVVEEELKKADALLKGGKAGAGFYEQACQANLALKP
AAPQQGAVVPAALPAGQPVQGLAVRADDPIRGNPKAPVTIVLFSDFQCPFCARVEPTLAQVQKTYGDKVRVVWKHQPLGM
HPNALPAAEAAEAAREQGKFWQMHEKLFASQRELSDALYERAAREIGLDVARFDAARRSGRARTRIAEDQALAARIGAQA
TPTMFVNGVKVEGAVPFEQIRAVVDAELARR
>Mature_671_residues
MKHVSWVVALVIGFAIGFVGRGSWDAGGRPSRAPVGAPTRARPVEDPKAVYRVPADDSPVRGPADALVTIVESSDFQCPY
CKRGAATMKQVEEAYRGKVRFVFKHNPLSFHPQAMPAALAAEEARAQGGDEKFWALHDKLFDSAPALDQAAIEKAAGELG
LDVAKVREAMQAGTHRARIERDQKLVVGLGAPATPTFFVNGRKIAGAQPIEAFRAVIDEELARAEQLVRSGTPASQVYAK
AIERGATAPVFLPGTVPPPTAAAPSPAAPAPAAPAAPPPATYAKVPLRADDPARGPADAKLTVVLFSDFQCPFCSRVEPT
LKQLEQAYPGQVRIVWKHQPLSFHPNAMPAAIAAEAAREQGKFWPMHEKLFSNQQALSPATYEQYAKELGLDLRKFQAAV
AARKGADRIAADQQLAGSVGANGTPTMFFNCRQVVGALPLERMRPVVEEELKKADALLKGGKAGAGFYEQACQANLALKP
AAPQQGAVVPAALPAGQPVQGLAVRADDPIRGNPKAPVTIVLFSDFQCPFCARVEPTLAQVQKTYGDKVRVVWKHQPLGM
HPNALPAAEAAEAAREQGKFWQMHEKLFASQRELSDALYERAAREIGLDVARFDAARRSGRARTRIAEDQALAARIGAQA
TPTMFVNGVKVEGAVPFEQIRAVVDAELARR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 71935; Mature: 71935

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVSWVVALVIGFAIGFVGRGSWDAGGRPSRAPVGAPTRARPVEDPKAVYRVPADDSPV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCC
RGPADALVTIVESSDFQCPYCKRGAATMKQVEEAYRGKVRFVFKHNPLSFHPQAMPAALA
CCCHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
AEEARAQGGDEKFWALHDKLFDSAPALDQAAIEKAAGELGLDVAKVREAMQAGTHRARIE
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHC
RDQKLVVGLGAPATPTFFVNGRKIAGAQPIEAFRAVIDEELARAEQLVRSGTPASQVYAK
CCCEEEEEECCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AIERGATAPVFLPGTVPPPTAAAPSPAAPAPAAPAAPPPATYAKVPLRADDPARGPADAK
HHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCE
LTVVLFSDFQCPFCSRVEPTLKQLEQAYPGQVRIVWKHQPLSFHPNAMPAAIAAEAAREQ
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHC
GKFWPMHEKLFSNQQALSPATYEQYAKELGLDLRKFQAAVAARKGADRIAADQQLAGSVG
CCCCCHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
ANGTPTMFFNCRQVVGALPLERMRPVVEEELKKADALLKGGKAGAGFYEQACQANLALKP
CCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEECC
AAPQQGAVVPAALPAGQPVQGLAVRADDPIRGNPKAPVTIVLFSDFQCPFCARVEPTLAQ
CCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
VQKTYGDKVRVVWKHQPLGMHPNALPAAEAAEAAREQGKFWQMHEKLFASQRELSDALYE
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RAAREIGLDVARFDAARRSGRARTRIAEDQALAARIGAQATPTMFVNGVKVEGAVPFEQI
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECEEECCCCCHHHH
RAVVDAELARR
HHHHHHHHHCC
>Mature Secondary Structure
MKHVSWVVALVIGFAIGFVGRGSWDAGGRPSRAPVGAPTRARPVEDPKAVYRVPADDSPV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCC
RGPADALVTIVESSDFQCPYCKRGAATMKQVEEAYRGKVRFVFKHNPLSFHPQAMPAALA
CCCHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
AEEARAQGGDEKFWALHDKLFDSAPALDQAAIEKAAGELGLDVAKVREAMQAGTHRARIE
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHC
RDQKLVVGLGAPATPTFFVNGRKIAGAQPIEAFRAVIDEELARAEQLVRSGTPASQVYAK
CCCEEEEEECCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AIERGATAPVFLPGTVPPPTAAAPSPAAPAPAAPAAPPPATYAKVPLRADDPARGPADAK
HHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCE
LTVVLFSDFQCPFCSRVEPTLKQLEQAYPGQVRIVWKHQPLSFHPNAMPAAIAAEAAREQ
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHC
GKFWPMHEKLFSNQQALSPATYEQYAKELGLDLRKFQAAVAARKGADRIAADQQLAGSVG
CCCCCHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
ANGTPTMFFNCRQVVGALPLERMRPVVEEELKKADALLKGGKAGAGFYEQACQANLALKP
CCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEECC
AAPQQGAVVPAALPAGQPVQGLAVRADDPIRGNPKAPVTIVLFSDFQCPFCARVEPTLAQ
CCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
VQKTYGDKVRVVWKHQPLGMHPNALPAAEAAEAAREQGKFWQMHEKLFASQRELSDALYE
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RAAREIGLDVARFDAARRSGRARTRIAEDQALAARIGAQATPTMFVNGVKVEGAVPFEQI
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECEEECCCCCHHHH
RAVVDAELARR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA