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The map label for this gene is yjjL [H]

Identifier: 220919211

GI number: 220919211

Start: 4618571

End: 4619851

Strand: Direct

Name: yjjL [H]

Synonym: A2cp1_4131

Alternate gene names: 220919211

Gene position: 4618571-4619851 (Clockwise)

Preceding gene: 220919209

Following gene: 220919212

Centisome position: 91.83

GC content: 74.79

Gene sequence:

>1281_bases
GTGCACTCCACGCCCGGCGCCGCCCGCCTCTTCCATGGCCCCGGCGGCCGCGCGCTCCTCGTCCTCACCTTCATCAACCT
GTTCAACTACCTCGATCGGTTCGTGGTCTCGGCGCTGGTCGAGAGCCTGCGCGCGGACCTGTGGCTCACCGACACGCGCC
TCGGCTGGCTGATGACGAGCTTCACCATCGTCTACGCGCTCGCCTCCCCGGTGTTCGGCGCGCTGGGCGACCGCCGGTCC
CGTCCCCCGCTCGTCGCGCTCGGCGTCTTCCTCTGGAGCGCCGCCACCATGCTCTCCGGCGCGGCGCGCGGCTTCTTCAC
GCTGCTCCTCGCCCGCGCCGCGGTGGGCGTGGGCGAGGCCGCGTACGGCACGCTCTCGCCCGGCCTGCTCGCCGACTACT
TCGGCAAGGACCGCCGCGGCCGCGCCTACGCGACGTTCTTCGCCGCCATCCCCATCGGCTCCGCGCTCGGGTACATCGTG
GGCGGCCTCGTCGAGCACCGCTTCGGCTGGCGGACGGCTTTCGTCATCTCCGGCGCGCCCGGCGTGCTGCTCGCCTACTG
GTGCCTGCGCCTGCCCGACCCGCCGCGCGGCGCGAGCGAGCGCCCCTGGCTCGAGCTCGGGAAGCGTGGGCTCGCCGCGA
CCTATCGCCGGCTCCTCGCGAACCGGCCCTACGTGCTCGCCGTGGCGGGCTACGCCGCCTACACGTTCGCGGTGGGCGGC
ATGGCGTTCTGGATGCCCGCGTTCCTGGAGCGCTCGCGCGGCGTGCCCCGCGCCATCGCCACCGTCCAGTTCGGCGCGGT
GGTGGTGATGACCGGGTTCGCCGGCACGTTCGCCGGCGGCTTCTTCGCCGACTGGCTCCGCCGCCGCCGGCGCGAGGCCG
ACCTGTGGGTCTCCGGCATCGCCACGCTGCTCGCCGCGCCGCTCTCGCTGGCGGTGTTCCTCACCTGGCGCCCCGGGCTC
TACCTGTCCGCGCTCATCGCCGCGCAGCTCCTGCTGTTCGCGTCCTCCGGGCCCATCAACGCCGCGCTCATGAACGTGGT
CCCGCCCGCCGAGCGGGCCACCGCGGCGGCGCTCTCCATCCTCGCCATCCACGTGTTCGGCGACCTGCCCTCGCCCACGC
TCATCGGCGTGCTGTCCGACCACAGCTCGCTCGGGCGCGCCGTGCTCATCGTGCCCGCCGCGATCCTGATTTCCGGGGCG
ATCTGGACGTGGGCGGCGTGGCGCGGGGAGCGGGCGGCGGCGTTGGCCGGCGCCGGCCCGGGCGACGACCGCGCGGCGTA
G

Upstream 100 bases:

>100_bases
CCGCGCGCCTCCCCGCCGCCGCGCGGGCCCCGGATGCGCGCCGTCCCGGAGGGCACTCCGCGCTCGACCGCGCGCCGGGG
CGCAGGTACGCTGCCGCACC

Downstream 100 bases:

>100_bases
TGCTAGCCCGCGCTCCGCTGCGGCGACTCCTCGGGGGCCCCGACCCCGGGGCCCCGACCCCGGGGGGCCCCGACCCAGAG
TAACGCGATTCGGCCGCCCG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MHSTPGAARLFHGPGGRALLVLTFINLFNYLDRFVVSALVESLRADLWLTDTRLGWLMTSFTIVYALASPVFGALGDRRS
RPPLVALGVFLWSAATMLSGAARGFFTLLLARAAVGVGEAAYGTLSPGLLADYFGKDRRGRAYATFFAAIPIGSALGYIV
GGLVEHRFGWRTAFVISGAPGVLLAYWCLRLPDPPRGASERPWLELGKRGLAATYRRLLANRPYVLAVAGYAAYTFAVGG
MAFWMPAFLERSRGVPRAIATVQFGAVVVMTGFAGTFAGGFFADWLRRRRREADLWVSGIATLLAAPLSLAVFLTWRPGL
YLSALIAAQLLLFASSGPINAALMNVVPPAERATAAALSILAIHVFGDLPSPTLIGVLSDHSSLGRAVLIVPAAILISGA
IWTWAAWRGERAAALAGAGPGDDRAA

Sequences:

>Translated_426_residues
MHSTPGAARLFHGPGGRALLVLTFINLFNYLDRFVVSALVESLRADLWLTDTRLGWLMTSFTIVYALASPVFGALGDRRS
RPPLVALGVFLWSAATMLSGAARGFFTLLLARAAVGVGEAAYGTLSPGLLADYFGKDRRGRAYATFFAAIPIGSALGYIV
GGLVEHRFGWRTAFVISGAPGVLLAYWCLRLPDPPRGASERPWLELGKRGLAATYRRLLANRPYVLAVAGYAAYTFAVGG
MAFWMPAFLERSRGVPRAIATVQFGAVVVMTGFAGTFAGGFFADWLRRRRREADLWVSGIATLLAAPLSLAVFLTWRPGL
YLSALIAAQLLLFASSGPINAALMNVVPPAERATAAALSILAIHVFGDLPSPTLIGVLSDHSSLGRAVLIVPAAILISGA
IWTWAAWRGERAAALAGAGPGDDRAA
>Mature_426_residues
MHSTPGAARLFHGPGGRALLVLTFINLFNYLDRFVVSALVESLRADLWLTDTRLGWLMTSFTIVYALASPVFGALGDRRS
RPPLVALGVFLWSAATMLSGAARGFFTLLLARAAVGVGEAAYGTLSPGLLADYFGKDRRGRAYATFFAAIPIGSALGYIV
GGLVEHRFGWRTAFVISGAPGVLLAYWCLRLPDPPRGASERPWLELGKRGLAATYRRLLANRPYVLAVAGYAAYTFAVGG
MAFWMPAFLERSRGVPRAIATVQFGAVVVMTGFAGTFAGGFFADWLRRRRREADLWVSGIATLLAAPLSLAVFLTWRPGL
YLSALIAAQLLLFASSGPINAALMNVVPPAERATAAALSILAIHVFGDLPSPTLIGVLSDHSSLGRAVLIVPAAILISGA
IWTWAAWRGERAAALAGAGPGDDRAA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=433, Percent_Identity=32.1016166281755, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI215490096, Length=391, Percent_Identity=37.3401534526854, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI14042968, Length=391, Percent_Identity=37.3401534526854, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI194239645, Length=382, Percent_Identity=33.7696335078534, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI215490100, Length=372, Percent_Identity=36.0215053763441, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI215490102, Length=378, Percent_Identity=34.1269841269841, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI215490098, Length=378, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI2367379, Length=281, Percent_Identity=28.4697508896797, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789152, Length=305, Percent_Identity=22.6229508196721, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082404, Length=376, Percent_Identity=21.8085106382979, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789515, Length=299, Percent_Identity=25.752508361204, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082320, Length=298, Percent_Identity=21.8120805369128, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71992409, Length=386, Percent_Identity=30.3108808290155, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17557872, Length=395, Percent_Identity=29.3670886075949, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI193209775, Length=442, Percent_Identity=27.6018099547511, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17539092, Length=390, Percent_Identity=29.2307692307692, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24654041, Length=375, Percent_Identity=34.6666666666667, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24654037, Length=375, Percent_Identity=34.6666666666667, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17864456, Length=375, Percent_Identity=35.4666666666667, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24654039, Length=375, Percent_Identity=35.4666666666667, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24654044, Length=235, Percent_Identity=39.5744680851064, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45263; Mature: 45263

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTPGAARLFHGPGGRALLVLTFINLFNYLDRFVVSALVESLRADLWLTDTRLGWLMTS
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
FTIVYALASPVFGALGDRRSRPPLVALGVFLWSAATMLSGAARGFFTLLLARAAVGVGEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AYGTLSPGLLADYFGKDRRGRAYATFFAAIPIGSALGYIVGGLVEHRFGWRTAFVISGAP
HCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
GVLLAYWCLRLPDPPRGASERPWLELGKRGLAATYRRLLANRPYVLAVAGYAAYTFAVGG
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
MAFWMPAFLERSRGVPRAIATVQFGAVVVMTGFAGTFAGGFFADWLRRRRREADLWVSGI
HHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLLAAPLSLAVFLTWRPGLYLSALIAAQLLLFASSGPINAALMNVVPPAERATAAALSI
HHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHH
LAIHVFGDLPSPTLIGVLSDHSSLGRAVLIVPAAILISGAIWTWAAWRGERAAALAGAGP
HHHHHHCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GDDRAA
CCCCCC
>Mature Secondary Structure
MHSTPGAARLFHGPGGRALLVLTFINLFNYLDRFVVSALVESLRADLWLTDTRLGWLMTS
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
FTIVYALASPVFGALGDRRSRPPLVALGVFLWSAATMLSGAARGFFTLLLARAAVGVGEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AYGTLSPGLLADYFGKDRRGRAYATFFAAIPIGSALGYIVGGLVEHRFGWRTAFVISGAP
HCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
GVLLAYWCLRLPDPPRGASERPWLELGKRGLAATYRRLLANRPYVLAVAGYAAYTFAVGG
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
MAFWMPAFLERSRGVPRAIATVQFGAVVVMTGFAGTFAGGFFADWLRRRRREADLWVSGI
HHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLLAAPLSLAVFLTWRPGLYLSALIAAQLLLFASSGPINAALMNVVPPAERATAAALSI
HHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHH
LAIHVFGDLPSPTLIGVLSDHSSLGRAVLIVPAAILISGAIWTWAAWRGERAAALAGAGP
HHHHHHCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GDDRAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]