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The map label for this gene is rsmB [H]

Identifier: 220919194

GI number: 220919194

Start: 4600682

End: 4602049

Strand: Direct

Name: rsmB [H]

Synonym: A2cp1_4114

Alternate gene names: 220919194

Gene position: 4600682-4602049 (Clockwise)

Preceding gene: 220919193

Following gene: 220919195

Centisome position: 91.48

GC content: 80.7

Gene sequence:

>1368_bases
ATGGCCGGCCGCCCGACGAACCCGGCCGCGGGCGCGCGCGGCATCGCGTTCGACGTGCTCCGGCGCGTCGAGGAGGGCGG
CGCGTACGCGTCGCGCGCGCTCGACGCCGCGCTCGGCGCGGCCGGCGCGCTCGATCCGCGCGAGGCAGGGCTCGCCACCG
AGCTGGTCTACGGGACCCTGCGGCGGGCGCTCGCGCTCGATGCCGCGCTGGCGCCGCACTCCCGCCGCGCGCTCGCCGAG
CTGGACCCGGCCGCGCGCGTGGCGCTGCGGCTCGGCGCCTACCAGCTGCTCGTGCTCGGCACGCCCGCGCACGCCGCCGT
CGGCGAGACGGTGGCGCTCGCGAAGGCGGTGGACCACGGCCGCGCCGCCGGGTACGTGAACGCGGTCCTCCGGTCGCTGT
CGCGCGCGGCGCGCTTCCCGGACCCGCCGGCGCTCGAGGCGGATCCGGCCGGCCACGTCGCCGCGGCCGAGGCGCTGCCG
CGCTGGGTGGCGGAGGAGTGGGTGGGCTGGCTGGGCGCCGGCGAGGCGCTGGCGCTCGCCCGGGCCATGAACGCGCCCGC
CCCGCTGTGCGTGCGCACGCCGGATCGCGAGGCGCTGCTCGCACGCGCCCGCGCCGCCGGCCTCGCCGCGGCGCCGGCCG
CCCGGGCGCCGGGCGGGGTGGTGCTCACCGGCGCGTCGGTCGGCGAGCTGGCCCGCGCGGCCGGCGGCGTGCCGTTCCAG
GTCCAGGACGAGGCCGCCCAGCTCGTGACGCTCCTCGCGGCGGGCGACCTGGCCGGCCGGCCGGCCCGCGTGCTCGACGC
CTGCGCCGCGCCGGGCGGCAAGGCGTTCCACCTGGCCGAGCTGCTCGGGCCCGGCGCCGAGGTGGTCGCGATCGAGCTCC
ACCCGCGCAAGGCCGACGAGCTGGCCCGCGAGGCGGCGCGGCGTGGCCTGCCCGCGGTGCGGGTGGTGTGCGCCGACGCA
GGGAAGCCCATCCCCGGGCTCGAGCCCGGGAGCTTCGACGCGGTGCTGGTGGACGCGCCCTGCGCCGGCCTCGGCACGCT
CCGGCGCCACCCCGAGCTGAAGCTGCGCCGGGCCCCCGGGGACCTGCCGCGCATGGCCGCGCTCCAGCGCAAGATCGCCC
TGAACGCGGCGCGCTACGCCCGGCCCGGCGCGCCGGTCGTCTACTCGATCTGCTCGCTCTCCCGCGCCGAGGGGCCGGAG
GTGGTCGAGACGCTGCTCGGCGAGGGCTTCCGCCGCGCCCCGCCGCCCGCCGGCTTCCCGGCCGACGTGCTCGACGCGCG
CGGCGATCTCCTCACCCTCCCGAGCCGCCACGGGACCGACGGCTTCTACGCCGCGCGGCTGGTGCGGGACGTGCCCTCCA
CCGACTAG

Upstream 100 bases:

>100_bases
CGCTGCTCGTCACGCGCGTGCAGCTGGAGGGCAGGCCGGCGCAGTCGGCGCTCGACCTCGCGAACGGCCTGCGCAGGAAG
CGCTTCCGGCTGGGCACCTG

Downstream 100 bases:

>100_bases
GATCGCCCCATGCCCCTGCCCATCCGCATCGCCCCGTCGATCCTCTCCGCCGACTTCGGCCGGCTCGCCGAGGAGGTCCG
CGCGGTCGAGGCCGCCGGCG

Product: NusB/RsmB/TIM44

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAGRPTNPAAGARGIAFDVLRRVEEGGAYASRALDAALGAAGALDPREAGLATELVYGTLRRALALDAALAPHSRRALAE
LDPAARVALRLGAYQLLVLGTPAHAAVGETVALAKAVDHGRAAGYVNAVLRSLSRAARFPDPPALEADPAGHVAAAEALP
RWVAEEWVGWLGAGEALALARAMNAPAPLCVRTPDREALLARARAAGLAAAPAARAPGGVVLTGASVGELARAAGGVPFQ
VQDEAAQLVTLLAAGDLAGRPARVLDACAAPGGKAFHLAELLGPGAEVVAIELHPRKADELAREAARRGLPAVRVVCADA
GKPIPGLEPGSFDAVLVDAPCAGLGTLRRHPELKLRRAPGDLPRMAALQRKIALNAARYARPGAPVVYSICSLSRAEGPE
VVETLLGEGFRRAPPPAGFPADVLDARGDLLTLPSRHGTDGFYAARLVRDVPSTD

Sequences:

>Translated_455_residues
MAGRPTNPAAGARGIAFDVLRRVEEGGAYASRALDAALGAAGALDPREAGLATELVYGTLRRALALDAALAPHSRRALAE
LDPAARVALRLGAYQLLVLGTPAHAAVGETVALAKAVDHGRAAGYVNAVLRSLSRAARFPDPPALEADPAGHVAAAEALP
RWVAEEWVGWLGAGEALALARAMNAPAPLCVRTPDREALLARARAAGLAAAPAARAPGGVVLTGASVGELARAAGGVPFQ
VQDEAAQLVTLLAAGDLAGRPARVLDACAAPGGKAFHLAELLGPGAEVVAIELHPRKADELAREAARRGLPAVRVVCADA
GKPIPGLEPGSFDAVLVDAPCAGLGTLRRHPELKLRRAPGDLPRMAALQRKIALNAARYARPGAPVVYSICSLSRAEGPE
VVETLLGEGFRRAPPPAGFPADVLDARGDLLTLPSRHGTDGFYAARLVRDVPSTD
>Mature_454_residues
AGRPTNPAAGARGIAFDVLRRVEEGGAYASRALDAALGAAGALDPREAGLATELVYGTLRRALALDAALAPHSRRALAEL
DPAARVALRLGAYQLLVLGTPAHAAVGETVALAKAVDHGRAAGYVNAVLRSLSRAARFPDPPALEADPAGHVAAAEALPR
WVAEEWVGWLGAGEALALARAMNAPAPLCVRTPDREALLARARAAGLAAAPAARAPGGVVLTGASVGELARAAGGVPFQV
QDEAAQLVTLLAAGDLAGRPARVLDACAAPGGKAFHLAELLGPGAEVVAIELHPRKADELAREAARRGLPAVRVVCADAG
KPIPGLEPGSFDAVLVDAPCAGLGTLRRHPELKLRRAPGDLPRMAALQRKIALNAARYARPGAPVVYSICSLSRAEGPEV
VETLLGEGFRRAPPPAGFPADVLDARGDLLTLPSRHGTDGFYAARLVRDVPSTD

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=151, Percent_Identity=33.112582781457, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI76150625, Length=206, Percent_Identity=28.1553398058252, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI76150623, Length=206, Percent_Identity=28.1553398058252, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI301336155, Length=159, Percent_Identity=32.0754716981132, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI39995082, Length=159, Percent_Identity=32.0754716981132, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI11545785, Length=160, Percent_Identity=32.5, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367212, Length=448, Percent_Identity=28.5714285714286, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081985, Length=229, Percent_Identity=31.4410480349345, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536757, Length=222, Percent_Identity=29.2792792792793, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=154, Percent_Identity=33.7662337662338, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=212, Percent_Identity=25.9433962264151, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=206, Percent_Identity=30.0970873786408, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355201, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356513, Length=151, Percent_Identity=32.4503311258278, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668781, Length=166, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: 2.1.1.-

Molecular weight: Translated: 46591; Mature: 46460

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRPTNPAAGARGIAFDVLRRVEEGGAYASRALDAALGAAGALDPREAGLATELVYGTL
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RRALALDAALAPHSRRALAELDPAARVALRLGAYQLLVLGTPAHAAVGETVALAKAVDHG
HHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCC
RAAGYVNAVLRSLSRAARFPDPPALEADPAGHVAAAEALPRWVAEEWVGWLGAGEALALA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RAMNAPAPLCVRTPDREALLARARAAGLAAAPAARAPGGVVLTGASVGELARAAGGVPFQ
HHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCEE
VQDEAAQLVTLLAAGDLAGRPARVLDACAAPGGKAFHLAELLGPGAEVVAIELHPRKADE
EHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
LAREAARRGLPAVRVVCADAGKPIPGLEPGSFDAVLVDAPCAGLGTLRRHPELKLRRAPG
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEECCCC
DLPRMAALQRKIALNAARYARPGAPVVYSICSLSRAEGPEVVETLLGEGFRRAPPPAGFP
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
ADVLDARGDLLTLPSRHGTDGFYAARLVRDVPSTD
HHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGRPTNPAAGARGIAFDVLRRVEEGGAYASRALDAALGAAGALDPREAGLATELVYGTL
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RRALALDAALAPHSRRALAELDPAARVALRLGAYQLLVLGTPAHAAVGETVALAKAVDHG
HHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCC
RAAGYVNAVLRSLSRAARFPDPPALEADPAGHVAAAEALPRWVAEEWVGWLGAGEALALA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RAMNAPAPLCVRTPDREALLARARAAGLAAAPAARAPGGVVLTGASVGELARAAGGVPFQ
HHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCEE
VQDEAAQLVTLLAAGDLAGRPARVLDACAAPGGKAFHLAELLGPGAEVVAIELHPRKADE
EHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
LAREAARRGLPAVRVVCADAGKPIPGLEPGSFDAVLVDAPCAGLGTLRRHPELKLRRAPG
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEECCCC
DLPRMAALQRKIALNAARYARPGAPVVYSICSLSRAEGPEVVETLLGEGFRRAPPPAGFP
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
ADVLDARGDLLTLPSRHGTDGFYAARLVRDVPSTD
HHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]