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The map label for this gene is aceB [H]

Identifier: 220919127

GI number: 220919127

Start: 4521220

End: 4523523

Strand: Direct

Name: aceB [H]

Synonym: A2cp1_4047

Alternate gene names: 220919127

Gene position: 4521220-4523523 (Clockwise)

Preceding gene: 220919126

Following gene: 220919129

Centisome position: 89.9

GC content: 71.66

Gene sequence:

>2304_bases
ATGATCCGCGCGGACATCCTCGACCAGTTCCCCGACCTGTTCGGCCGCAAGCGCGTCAACGGCCGCGAGCTCGACGTGGA
CGCGACCATCGAGACGCTCACCCGCGAGCTCGAGCCGGACATCGAGGCCGCGCTGACCGCGCGCGGCGCGCTGCTCCGCT
CGCCCGAGCCGGTGGCCACGAAGTACGCGTGGCCGCACTGGAACGAGGCGTTCGAGGATCCCGTGGGCGGGAGCGCCTGG
ACGTTCCGCCAGATCGTCCAGGGCATGATCGACAACTTCCTCGGCAAGGAGAGCCCGCTGCGCTGGCGGCTCAACGACGA
GGTGCCGATCCCCGAGCACGTCCACCCGTCGCGCAACCCGGGCCTGGAGCTGACCGGGCCCTGGCACCCGCTCGACATGG
CGTTCAACGCGCTCAACAGCCCGGCGCCGATGAACATGCCGGACTTCGAGGACGCCTCGCCGCCGCACTTCCGCCCCGAC
GGCGCGCCCGCGCGCGAGCCGGTGGGCGTGTTCGCGGCGCTCAAGAACGCGAAGGATATCTTCGAGGGGCGCTGGTCCGA
CCGCGCCTACGAGGTCGAGAAGAAGGGGAAGGTCCGCAGCTACCGGATCACGACGCCGCAGGCGAAGTGGCCCACGCGCC
TGGCGCGCCCGCCCAGCCTGCACGTGCGCTATGACCACGTCACCGTGGACGGCCGGCCCGCGCCGGGCCTGGTGGTGGTG
GCGACGCTCTGGACGCTGAACGGCTACGACCCGCTCACCCGCGTCGGCAGCGGCGCGTACTTCTACATCCCGAAGCTGCA
GACGCCGCGCGAGGCGCTCATCGTGGAGCGGCTGCTGTCGCGCCTGGAGGGGATGATCGGCGTGCCCGCCGGCACGCTCA
AGGCGAAGATGCTCTACGAGGAGGGGAACGCCGGCCGCCAGCTTCCCGCCATCGTCTGGACGCTGCGGCGGCGGCTGCTC
GGCACGAACGTCGGCCGCTGGGACTACCTCGGCAGCCTCATCGAGATGTGGAAGGACGATCCGCAGGGCGTCTTCCCCGA
CCCGCAGACCGTGGGCATGGCGACGCCCGGGATGCTCGCCTACCAGCGCTACAACGCGCTCCTCATGCTCATGGCCGGCA
TGAAGGACGGCGAGCTGACCCACGCCGCGCCCATCGGCGGCATGGCCGCGGTGATGATCTACCAGGGCGGCGATCCCTAC
GGCCGCGCGCGCTACAACCCGCTCGCGCTCCGCGCCATGGTGATCGACAAGCTGCGCGAGCGGTTGCTGGGCCTGTTCTT
CGTGCCCGACGCGCCGCTCCGGCCCGGCGAGCTCCCCACGCTCGACGCGATCCTCTCCGGCAAGGTCCGCGGCACGCTCC
ACGACGCCTACCGGCAGAGCTGGGTGGCGAGCCCGGAGCCCGAGTACGTGGGTGCCGGCAACGGCCCGCTCCGCGCGCGG
GTGGGCGCGCTGCAGGAGCTGCTCGACGCGCCGGTGGAGCTGGTGGACGCGGGCGGGAAGCCGGTGCCCACGGTGGCGAG
CGGGCTCTCAGACGCCGAGCGGGCCGTGTTCCACGCGCGCGGCCTGGTGGACGCGAACGGGCGCATCACGCCGTTCGTGC
TGGCGCGCGAGCACGTGGACGCGCCGGAGAAGCTCCTCGACCGGGCGCGCTGGGAGGCGATCTACCGGGTGCCCGAGGGC
GACGTCACCATCGAGCACGTCCAGCACGCGTTCTACATGGCGGCGAACTACGGGTTCCAGATCCTGAACGGCAACTTCGC
CGCCGCCATCGACGACTACGAGCTGAAGCTCCGCTTCATGAACGACCTCGCCACCTACCGCATCAACGTGTCCTGGCTGT
GGGCGCTCCTGCGTCACCAGGCGCCCGTCACGAAGGACGGCCACCTGCTCCGCGCCACGCTCACCGGGGACGGCGTGGTG
CTCGGCAAGCCCGCCGAGCCGGTGAAGGCCGGGACGCACCTCGATCGCGCGCTGTTCGAGAAGGTGTACACGTTCCACGG
TGAGTGGACGGACGCGTTCTTCGCCGAGCAGGACCGCCGCGGCGAGCCCGCGCGCTTCGACCGCTCCAAGGCGCCCGTCA
TCATGGAGCTGCTGCACCGGCAGCTCCTCTCCCCGCGCTACATTCAGCACAGCGCCCGCGCGCTGTTCGTGATCGGCGCC
GCCCGCCCCGAGGACCGCGCCGGCCTGCTCGACGCCATGTTCGACCTCGAGCGCGCCGACGTCGCCGCGCGGGTGGAGAA
GGGCGCGCTTCCGAAGGGCGCGCTGGAGGCGCACGACTACGTGAACGACGTGTTCGGGGGGTAG

Upstream 100 bases:

>100_bases
TCTCAGGTGCATGCCCCGCGGCGCGCGCGGGAGCACCTAAGCTGGACGCCCGCCGCGCGGCGCCTGCCGCCGGCGCGCGT
GCCAGCCACCGGAGGGCCTC

Downstream 100 bases:

>100_bases
GGCGAGGACGCCGGGTTCGATTCCCGGCGCCTCCACTCGCACGCCCCGCCGCCTCACCGCGCCATCAGCGCAAACACGCC
CCAGCCCAGGTATTCGCGGG

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 767; Mature: 767

Protein sequence:

>767_residues
MIRADILDQFPDLFGRKRVNGRELDVDATIETLTRELEPDIEAALTARGALLRSPEPVATKYAWPHWNEAFEDPVGGSAW
TFRQIVQGMIDNFLGKESPLRWRLNDEVPIPEHVHPSRNPGLELTGPWHPLDMAFNALNSPAPMNMPDFEDASPPHFRPD
GAPAREPVGVFAALKNAKDIFEGRWSDRAYEVEKKGKVRSYRITTPQAKWPTRLARPPSLHVRYDHVTVDGRPAPGLVVV
ATLWTLNGYDPLTRVGSGAYFYIPKLQTPREALIVERLLSRLEGMIGVPAGTLKAKMLYEEGNAGRQLPAIVWTLRRRLL
GTNVGRWDYLGSLIEMWKDDPQGVFPDPQTVGMATPGMLAYQRYNALLMLMAGMKDGELTHAAPIGGMAAVMIYQGGDPY
GRARYNPLALRAMVIDKLRERLLGLFFVPDAPLRPGELPTLDAILSGKVRGTLHDAYRQSWVASPEPEYVGAGNGPLRAR
VGALQELLDAPVELVDAGGKPVPTVASGLSDAERAVFHARGLVDANGRITPFVLAREHVDAPEKLLDRARWEAIYRVPEG
DVTIEHVQHAFYMAANYGFQILNGNFAAAIDDYELKLRFMNDLATYRINVSWLWALLRHQAPVTKDGHLLRATLTGDGVV
LGKPAEPVKAGTHLDRALFEKVYTFHGEWTDAFFAEQDRRGEPARFDRSKAPVIMELLHRQLLSPRYIQHSARALFVIGA
ARPEDRAGLLDAMFDLERADVAARVEKGALPKGALEAHDYVNDVFGG

Sequences:

>Translated_767_residues
MIRADILDQFPDLFGRKRVNGRELDVDATIETLTRELEPDIEAALTARGALLRSPEPVATKYAWPHWNEAFEDPVGGSAW
TFRQIVQGMIDNFLGKESPLRWRLNDEVPIPEHVHPSRNPGLELTGPWHPLDMAFNALNSPAPMNMPDFEDASPPHFRPD
GAPAREPVGVFAALKNAKDIFEGRWSDRAYEVEKKGKVRSYRITTPQAKWPTRLARPPSLHVRYDHVTVDGRPAPGLVVV
ATLWTLNGYDPLTRVGSGAYFYIPKLQTPREALIVERLLSRLEGMIGVPAGTLKAKMLYEEGNAGRQLPAIVWTLRRRLL
GTNVGRWDYLGSLIEMWKDDPQGVFPDPQTVGMATPGMLAYQRYNALLMLMAGMKDGELTHAAPIGGMAAVMIYQGGDPY
GRARYNPLALRAMVIDKLRERLLGLFFVPDAPLRPGELPTLDAILSGKVRGTLHDAYRQSWVASPEPEYVGAGNGPLRAR
VGALQELLDAPVELVDAGGKPVPTVASGLSDAERAVFHARGLVDANGRITPFVLAREHVDAPEKLLDRARWEAIYRVPEG
DVTIEHVQHAFYMAANYGFQILNGNFAAAIDDYELKLRFMNDLATYRINVSWLWALLRHQAPVTKDGHLLRATLTGDGVV
LGKPAEPVKAGTHLDRALFEKVYTFHGEWTDAFFAEQDRRGEPARFDRSKAPVIMELLHRQLLSPRYIQHSARALFVIGA
ARPEDRAGLLDAMFDLERADVAARVEKGALPKGALEAHDYVNDVFGG
>Mature_767_residues
MIRADILDQFPDLFGRKRVNGRELDVDATIETLTRELEPDIEAALTARGALLRSPEPVATKYAWPHWNEAFEDPVGGSAW
TFRQIVQGMIDNFLGKESPLRWRLNDEVPIPEHVHPSRNPGLELTGPWHPLDMAFNALNSPAPMNMPDFEDASPPHFRPD
GAPAREPVGVFAALKNAKDIFEGRWSDRAYEVEKKGKVRSYRITTPQAKWPTRLARPPSLHVRYDHVTVDGRPAPGLVVV
ATLWTLNGYDPLTRVGSGAYFYIPKLQTPREALIVERLLSRLEGMIGVPAGTLKAKMLYEEGNAGRQLPAIVWTLRRRLL
GTNVGRWDYLGSLIEMWKDDPQGVFPDPQTVGMATPGMLAYQRYNALLMLMAGMKDGELTHAAPIGGMAAVMIYQGGDPY
GRARYNPLALRAMVIDKLRERLLGLFFVPDAPLRPGELPTLDAILSGKVRGTLHDAYRQSWVASPEPEYVGAGNGPLRAR
VGALQELLDAPVELVDAGGKPVPTVASGLSDAERAVFHARGLVDANGRITPFVLAREHVDAPEKLLDRARWEAIYRVPEG
DVTIEHVQHAFYMAANYGFQILNGNFAAAIDDYELKLRFMNDLATYRINVSWLWALLRHQAPVTKDGHLLRATLTGDGVV
LGKPAEPVKAGTHLDRALFEKVYTFHGEWTDAFFAEQDRRGEPARFDRSKAPVIMELLHRQLLSPRYIQHSARALFVIGA
ARPEDRAGLLDAMFDLERADVAARVEKGALPKGALEAHDYVNDVFGG

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=341, Percent_Identity=30.791788856305, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17561814, Length=281, Percent_Identity=28.8256227758007, Blast_Score=112, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71982926, Length=269, Percent_Identity=28.996282527881, Blast_Score=112, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324212, Length=350, Percent_Identity=31.1428571428571, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322222, Length=303, Percent_Identity=29.7029702970297, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 85240; Mature: 85240

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRADILDQFPDLFGRKRVNGRELDVDATIETLTRELEPDIEAALTARGALLRSPEPVAT
CCCHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
KYAWPHWNEAFEDPVGGSAWTFRQIVQGMIDNFLGKESPLRWRLNDEVPIPEHVHPSRNP
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC
GLELTGPWHPLDMAFNALNSPAPMNMPDFEDASPPHFRPDGAPAREPVGVFAALKNAKDI
CCEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FEGRWSDRAYEVEKKGKVRSYRITTPQAKWPTRLARPPSLHVRYDHVTVDGRPAPGLVVV
HCCCCCCCCEEHHCCCCEEEEEECCCCCCCCHHHCCCCCEEEEEEEEEECCCCCCCEEEE
ATLWTLNGYDPLTRVGSGAYFYIPKLQTPREALIVERLLSRLEGMIGVPAGTLKAKMLYE
EEEHHCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEE
EGNAGRQLPAIVWTLRRRLLGTNVGRWDYLGSLIEMWKDDPQGVFPDPQTVGMATPGMLA
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
YQRYNALLMLMAGMKDGELTHAAPIGGMAAVMIYQGGDPYGRARYNPLALRAMVIDKLRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RLLGLFFVPDAPLRPGELPTLDAILSGKVRGTLHDAYRQSWVASPEPEYVGAGNGPLRAR
HHHEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHH
VGALQELLDAPVELVDAGGKPVPTVASGLSDAERAVFHARGLVDANGRITPFVLAREHVD
HHHHHHHHHCCHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCEECCCCCEEEEEEEHHHCC
APEKLLDRARWEAIYRVPEGDVTIEHVQHAFYMAANYGFQILNGNFAAAIDDYELKLRFM
CHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHCCCEEEECCCEEEEECCHHEEEEEH
NDLATYRINVSWLWALLRHQAPVTKDGHLLRATLTGDGVVLGKPAEPVKAGTHLDRALFE
HCHHHEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHHHH
KVYTFHGEWTDAFFAEQDRRGEPARFDRSKAPVIMELLHRQLLSPRYIQHSARALFVIGA
HHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEEC
ARPEDRAGLLDAMFDLERADVAARVEKGALPKGALEAHDYVNDVFGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRADILDQFPDLFGRKRVNGRELDVDATIETLTRELEPDIEAALTARGALLRSPEPVAT
CCCHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
KYAWPHWNEAFEDPVGGSAWTFRQIVQGMIDNFLGKESPLRWRLNDEVPIPEHVHPSRNP
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC
GLELTGPWHPLDMAFNALNSPAPMNMPDFEDASPPHFRPDGAPAREPVGVFAALKNAKDI
CCEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FEGRWSDRAYEVEKKGKVRSYRITTPQAKWPTRLARPPSLHVRYDHVTVDGRPAPGLVVV
HCCCCCCCCEEHHCCCCEEEEEECCCCCCCCHHHCCCCCEEEEEEEEEECCCCCCCEEEE
ATLWTLNGYDPLTRVGSGAYFYIPKLQTPREALIVERLLSRLEGMIGVPAGTLKAKMLYE
EEEHHCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEEEEEE
EGNAGRQLPAIVWTLRRRLLGTNVGRWDYLGSLIEMWKDDPQGVFPDPQTVGMATPGMLA
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
YQRYNALLMLMAGMKDGELTHAAPIGGMAAVMIYQGGDPYGRARYNPLALRAMVIDKLRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RLLGLFFVPDAPLRPGELPTLDAILSGKVRGTLHDAYRQSWVASPEPEYVGAGNGPLRAR
HHHEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHH
VGALQELLDAPVELVDAGGKPVPTVASGLSDAERAVFHARGLVDANGRITPFVLAREHVD
HHHHHHHHHCCHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCEECCCCCEEEEEEEHHHCC
APEKLLDRARWEAIYRVPEGDVTIEHVQHAFYMAANYGFQILNGNFAAAIDDYELKLRFM
CHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHCCCEEEECCCEEEEECCHHEEEEEH
NDLATYRINVSWLWALLRHQAPVTKDGHLLRATLTGDGVVLGKPAEPVKAGTHLDRALFE
HCHHHEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHHHH
KVYTFHGEWTDAFFAEQDRRGEPARFDRSKAPVIMELLHRQLLSPRYIQHSARALFVIGA
HHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEEC
ARPEDRAGLLDAMFDLERADVAARVEKGALPKGALEAHDYVNDVFGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]