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The map label for this gene is tsr [H]

Identifier: 220919119

GI number: 220919119

Start: 4504131

End: 4505786

Strand: Direct

Name: tsr [H]

Synonym: A2cp1_4039

Alternate gene names: 220919119

Gene position: 4504131-4505786 (Clockwise)

Preceding gene: 220919116

Following gene: 220919124

Centisome position: 89.56

GC content: 75.72

Gene sequence:

>1656_bases
ATGTCGACACTTCGCAACGCGAAGATCGCCACGCGCCTCACGGCGAGCTTCAGCCTGTACATGGTCATCGCGGTCTTCGT
GGCGGTCGCGCTGCTGTACGCCCTCGCCCGGGTGACCGATCGCGTGGCGGCGGTCTCGGCCGCCGCGCTCGATCGCGACG
TCCTCGCCCAGCGCGCCGCGCTCGCCACCGGTGACGCCGGCGGCCTGCTCGCGGAGGCGACCGCGGCCCCCGACGACGCG
CGCCGGGCGGCGCCGCTCTCGCACCTCGACCGCCTCCTCGACGAGGACGCGGCCGCGGCGCGCGCGCTCGGGGCGATGTC
GCTCGACGCGGAGGAGCGCGGGCTGCTCGGCCAGGCGGAGGCCGCCGGCGCCCGGCTCCGGGACGCGGCGACGCGCGCCC
GGCGCTCGCTGGGCCAGCCGGACGACCCGGTGCGCGCGACCGACCTGCAGCAGGTGATCTCGGCGCGCGCGGACCTGCAG
GGCGCCTGGCAGCGCCTGGCGGGGCTCGAGACCGAGCGCGTGCGGGAGGCGGCCGCCGCCGCCCAGGCCGACGCGGCCGT
GGTGCGGCTCTGGATCTACGCGGGCCTGACGCTCGCCGGCACGCTCGTGATCCTCGCGAGCGTGACGCTCACCCGCAGCA
TCACCGTCCCGCTGCGCGCGACGGTGGTCCACGCCGAGCGCATCGCGCGCGGCGACCTGCGCGAGGAGGTCGAGGTGACC
GGCCGCGACGAGATCGGTCAGCTCGAGCAGGCGATGCAGGCCATGACCGAGAAGCTGGCCGAGGTCATCGGCGAGGTGCG
CGGGAGCACCGACGCGCTCACCTCGGCCTCGCAGCAGCTCTCCGCCACGGCGCAGAACGTGTCGCAGGGCACCGGCGAGC
AGGCCGCGTCGGTGGAGGAGACCACCTCCTCGCTGGAGGAGATGAGCGCGTCGATCACGCAGAACGCCGAGAACAGCCGG
CAGACCGAGACGATGGCCCTGGAGGGCGCCCGCAACGCGCAGGAGAGCGGCGAGGCGGTGCAGCGCAGCGTGGAGGCGAT
GCGCACCATCGCCGAGAAGATCTCCATCATCGAGGAGATCGCCTACCAGACGAACCTGCTCGCGCTGAACGCGGCCATCG
AGGCGGCGCGCGCCGGCGAGCACGGTCGCGGGTTCGCGGTGGTCGCCACCGAGGTCCGCAAGCTGGCGGAGCGGGCGCAG
AAGTCCGCCGGGGAGATCGGCGCGCTGGCCGGCTCGTCGGTGGAGGTCGCCGAGCGCTCCGGCGCGCTCATCGCCGAGCT
GGTGCCGGCCATCCGCAAGACCTCCGACCTGGTGCAGGAGGTGGCGGCGGCCTCGCGCGAGCAGTCCACCGGCGTCCGCC
AGGTCACGAAGGCGATGGGCGTGGTGGACCAGGTCACGCAGCGGAACGCCTCCGCCGCCGAGGAGCTGTCGTCCACCGCC
GAGGAGATGTCCTCGCAGGCCGAGGCGCTCCAGCAGCTGGTGGCGTTCTTCCGGGTGCGCGAGGCCCACGCCCCGGCCCG
CCCGCGCCCGGCCCTGGCCGCGCCGCGGCTGCCGCCGCCCGCGCCGATGGCCGCCGCCGCGCGGGCCCCGGGTGCGCCGG
GCCGGGCGAACGGCAAGCCGGATGGGACGGTGGAGAAGGAGTTCAGGCGCTTCTGA

Upstream 100 bases:

>100_bases
GTCGGGGGCGCGCCGATTGCACCCGGCGTCACCTGAACGGTCGGTCCGAGTCGTCCGGCGCCGCCGCCCCCGCGCGGCGC
AGAGGGTGGGAGATCATCAG

Downstream 100 bases:

>100_bases
GCGGATCGACGGGCGCGTCCGAGGTCACCGCCACCAGCAGGTAGGGCCCGGCCGCCCCGATCCACGCCCGGAGCGCGGCG
CGGACCGGGCCCTCCAGCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSTLRNAKIATRLTASFSLYMVIAVFVAVALLYALARVTDRVAAVSAAALDRDVLAQRAALATGDAGGLLAEATAAPDDA
RRAAPLSHLDRLLDEDAAAARALGAMSLDAEERGLLGQAEAAGARLRDAATRARRSLGQPDDPVRATDLQQVISARADLQ
GAWQRLAGLETERVREAAAAAQADAAVVRLWIYAGLTLAGTLVILASVTLTRSITVPLRATVVHAERIARGDLREEVEVT
GRDEIGQLEQAMQAMTEKLAEVIGEVRGSTDALTSASQQLSATAQNVSQGTGEQAASVEETTSSLEEMSASITQNAENSR
QTETMALEGARNAQESGEAVQRSVEAMRTIAEKISIIEEIAYQTNLLALNAAIEAARAGEHGRGFAVVATEVRKLAERAQ
KSAGEIGALAGSSVEVAERSGALIAELVPAIRKTSDLVQEVAAASREQSTGVRQVTKAMGVVDQVTQRNASAAEELSSTA
EEMSSQAEALQQLVAFFRVREAHAPARPRPALAAPRLPPPAPMAAAARAPGAPGRANGKPDGTVEKEFRRF

Sequences:

>Translated_551_residues
MSTLRNAKIATRLTASFSLYMVIAVFVAVALLYALARVTDRVAAVSAAALDRDVLAQRAALATGDAGGLLAEATAAPDDA
RRAAPLSHLDRLLDEDAAAARALGAMSLDAEERGLLGQAEAAGARLRDAATRARRSLGQPDDPVRATDLQQVISARADLQ
GAWQRLAGLETERVREAAAAAQADAAVVRLWIYAGLTLAGTLVILASVTLTRSITVPLRATVVHAERIARGDLREEVEVT
GRDEIGQLEQAMQAMTEKLAEVIGEVRGSTDALTSASQQLSATAQNVSQGTGEQAASVEETTSSLEEMSASITQNAENSR
QTETMALEGARNAQESGEAVQRSVEAMRTIAEKISIIEEIAYQTNLLALNAAIEAARAGEHGRGFAVVATEVRKLAERAQ
KSAGEIGALAGSSVEVAERSGALIAELVPAIRKTSDLVQEVAAASREQSTGVRQVTKAMGVVDQVTQRNASAAEELSSTA
EEMSSQAEALQQLVAFFRVREAHAPARPRPALAAPRLPPPAPMAAAARAPGAPGRANGKPDGTVEKEFRRF
>Mature_550_residues
STLRNAKIATRLTASFSLYMVIAVFVAVALLYALARVTDRVAAVSAAALDRDVLAQRAALATGDAGGLLAEATAAPDDAR
RAAPLSHLDRLLDEDAAAARALGAMSLDAEERGLLGQAEAAGARLRDAATRARRSLGQPDDPVRATDLQQVISARADLQG
AWQRLAGLETERVREAAAAAQADAAVVRLWIYAGLTLAGTLVILASVTLTRSITVPLRATVVHAERIARGDLREEVEVTG
RDEIGQLEQAMQAMTEKLAEVIGEVRGSTDALTSASQQLSATAQNVSQGTGEQAASVEETTSSLEEMSASITQNAENSRQ
TETMALEGARNAQESGEAVQRSVEAMRTIAEKISIIEEIAYQTNLLALNAAIEAARAGEHGRGFAVVATEVRKLAERAQK
SAGEIGALAGSSVEVAERSGALIAELVPAIRKTSDLVQEVAAASREQSTGVRQVTKAMGVVDQVTQRNASAAEELSSTAE
EMSSQAEALQQLVAFFRVREAHAPARPRPALAAPRLPPPAPMAAAARAPGAPGRANGKPDGTVEKEFRRF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=373, Percent_Identity=38.6058981233244, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=37.797619047619, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1788195, Length=326, Percent_Identity=38.6503067484663, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=36.2880886426593, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789453, Length=305, Percent_Identity=29.8360655737705, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57764; Mature: 57632

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLRNAKIATRLTASFSLYMVIAVFVAVALLYALARVTDRVAAVSAAALDRDVLAQRAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGDAGGLLAEATAAPDDARRAAPLSHLDRLLDEDAAAARALGAMSLDAEERGLLGQAE
HHCCCCCCCHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHH
AAGARLRDAATRARRSLGQPDDPVRATDLQQVISARADLQGAWQRLAGLETERVREAAAA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AQADAAVVRLWIYAGLTLAGTLVILASVTLTRSITVPLRATVVHAERIARGDLREEVEVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHC
GRDEIGQLEQAMQAMTEKLAEVIGEVRGSTDALTSASQQLSATAQNVSQGTGEQAASVEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TTSSLEEMSASITQNAENSRQTETMALEGARNAQESGEAVQRSVEAMRTIAEKISIIEEI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYQTNLLALNAAIEAARAGEHGRGFAVVATEVRKLAERAQKSAGEIGALAGSSVEVAERS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHC
GALIAELVPAIRKTSDLVQEVAAASREQSTGVRQVTKAMGVVDQVTQRNASAAEELSSTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EEMSSQAEALQQLVAFFRVREAHAPARPRPALAAPRLPPPAPMAAAARAPGAPGRANGKP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
DGTVEKEFRRF
CCCHHHHHHCC
>Mature Secondary Structure 
STLRNAKIATRLTASFSLYMVIAVFVAVALLYALARVTDRVAAVSAAALDRDVLAQRAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGDAGGLLAEATAAPDDARRAAPLSHLDRLLDEDAAAARALGAMSLDAEERGLLGQAE
HHCCCCCCCHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHH
AAGARLRDAATRARRSLGQPDDPVRATDLQQVISARADLQGAWQRLAGLETERVREAAAA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AQADAAVVRLWIYAGLTLAGTLVILASVTLTRSITVPLRATVVHAERIARGDLREEVEVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHC
GRDEIGQLEQAMQAMTEKLAEVIGEVRGSTDALTSASQQLSATAQNVSQGTGEQAASVEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TTSSLEEMSASITQNAENSRQTETMALEGARNAQESGEAVQRSVEAMRTIAEKISIIEEI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYQTNLLALNAAIEAARAGEHGRGFAVVATEVRKLAERAQKSAGEIGALAGSSVEVAERS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHC
GALIAELVPAIRKTSDLVQEVAAASREQSTGVRQVTKAMGVVDQVTQRNASAAEELSSTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EEMSSQAEALQQLVAFFRVREAHAPARPRPALAAPRLPPPAPMAAAARAPGAPGRANGKP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
DGTVEKEFRRF
CCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]