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The map label for this gene is gph [C]

Identifier: 220919040

GI number: 220919040

Start: 4408788

End: 4409468

Strand: Direct

Name: gph [C]

Synonym: A2cp1_3955

Alternate gene names: 220919040

Gene position: 4408788-4409468 (Clockwise)

Preceding gene: 220919039

Following gene: 220919041

Centisome position: 87.66

GC content: 75.92

Gene sequence:

>681_bases
ATGGCCCTCGCCCCGGTCCGCGCCGCCGTCTTCGACGCTTACGGAACCCTGTTCGACGTGGCCAGCGCCGCCGCCGAGGC
GCGCGGCGCGCTCGGCGACCGCTGGCAGCCGCTCGCCGAGCTGTGGCGATCGAAGCAGCTCCAGTACACCTGGCTCCGCA
GCCTGGCCGGCCGCCACGCCGACTTCTGGCAGGTGACCGGCGACGCGGTCGACTTCGCGCTCGAGGCGCTCGGCCTCGCC
GACGCGGCGCTGCGCGCGCGGCTGATGGAGTCCTACCGCCACCTCGCCGCGTACCCCGAGGCGAAGGACGTCCTCACGCG
CCTGCGCGGCGCCGGCGTGCGCCTGGCGGTGCTCTCGAACGGTGCGCCGGCCATGCTCGCGTCCGCGGCGGAGAGCGCCG
GGCTCGCCGGCCTGCTCGAGCAGGTCCTCTCGGTGGAGGACGTGGGCGTGTACAAGCCGCACCCGGCCGTCTACCGGCTG
GCCGTGGACCGCCTCGGCGTGCCTGCGGCGGAGATCGTGTTCGTCTCCTCGAACGGCTGGGACGCGTTCGGCGCGAAGGC
GTTCGGCTACCAGGTGGCCTGGTGCAACCGCGCCGGCCAGCCCGCGGAGCGGCTCCCCGCCGCCCCCGACGCCGAGATCC
GCTCGCTCGCCGAGCTGCCGCCGCTGCTGGGCCTGCCGTAG

Upstream 100 bases:

>100_bases
AAGGCGGGAGCCCGGGGCGAGGACGCCGCCGAGGCCCGGCTCCTGGCGGCGACCCAGACGGCGAAGCGCAGGTAGCGCGC
GCGGCGCTAGCATCGGGGCC

Downstream 100 bases:

>100_bases
GGCGCTCGCCCTTCGACAGGCTCAGGGCGAGCGGGTCGGAAGCCGCTCGGGCTCAGGGTGAGCGGAGAGGATCCGCTCGT
GGTGAGCCCCGTCGAACCGC

Product: haloacid dehalogenase, type II

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase I; DEHCI; Halocarboxylic acid halidohydrolase I; L-2-haloacid dehalogenase I [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MALAPVRAAVFDAYGTLFDVASAAAEARGALGDRWQPLAELWRSKQLQYTWLRSLAGRHADFWQVTGDAVDFALEALGLA
DAALRARLMESYRHLAAYPEAKDVLTRLRGAGVRLAVLSNGAPAMLASAAESAGLAGLLEQVLSVEDVGVYKPHPAVYRL
AVDRLGVPAAEIVFVSSNGWDAFGAKAFGYQVAWCNRAGQPAERLPAAPDAEIRSLAELPPLLGLP

Sequences:

>Translated_226_residues
MALAPVRAAVFDAYGTLFDVASAAAEARGALGDRWQPLAELWRSKQLQYTWLRSLAGRHADFWQVTGDAVDFALEALGLA
DAALRARLMESYRHLAAYPEAKDVLTRLRGAGVRLAVLSNGAPAMLASAAESAGLAGLLEQVLSVEDVGVYKPHPAVYRL
AVDRLGVPAAEIVFVSSNGWDAFGAKAFGYQVAWCNRAGQPAERLPAAPDAEIRSLAELPPLLGLP
>Mature_225_residues
ALAPVRAAVFDAYGTLFDVASAAAEARGALGDRWQPLAELWRSKQLQYTWLRSLAGRHADFWQVTGDAVDFALEALGLAD
AALRARLMESYRHLAAYPEAKDVLTRLRGAGVRLAVLSNGAPAMLASAAESAGLAGLLEQVLSVEDVGVYKPHPAVYRLA
VDRLGVPAAEIVFVSSNGWDAFGAKAFGYQVAWCNRAGQPAERLPAAPDAEIRSLAELPPLLGLP

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 24065; Mature: 23933

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAPVRAAVFDAYGTLFDVASAAAEARGALGDRWQPLAELWRSKQLQYTWLRSLAGRHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
DFWQVTGDAVDFALEALGLADAALRARLMESYRHLAAYPEAKDVLTRLRGAGVRLAVLSN
CHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECC
GAPAMLASAAESAGLAGLLEQVLSVEDVGVYKPHPAVYRLAVDRLGVPAAEIVFVSSNGW
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCC
DAFGAKAFGYQVAWCNRAGQPAERLPAAPDAEIRSLAELPPLLGLP
CCCCCHHHCEEEEECCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ALAPVRAAVFDAYGTLFDVASAAAEARGALGDRWQPLAELWRSKQLQYTWLRSLAGRHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
DFWQVTGDAVDFALEALGLADAALRARLMESYRHLAAYPEAKDVLTRLRGAGVRLAVLSN
CHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECC
GAPAMLASAAESAGLAGLLEQVLSVEDVGVYKPHPAVYRLAVDRLGVPAAEIVFVSSNGW
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCC
DAFGAKAFGYQVAWCNRAGQPAERLPAAPDAEIRSLAELPPLLGLP
CCCCCHHHCEEEEECCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1995594 [H]