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The map label for this gene is queC [H]

Identifier: 220919027

GI number: 220919027

Start: 4394371

End: 4395075

Strand: Direct

Name: queC [H]

Synonym: A2cp1_3942

Alternate gene names: 220919027

Gene position: 4394371-4395075 (Clockwise)

Preceding gene: 220919026

Following gene: 220919028

Centisome position: 87.37

GC content: 74.04

Gene sequence:

>705_bases
ATGGCGAAGGCGACGAGCAAGGCGCGGCGCGCGGTGGTGCTCCTGTCGGGAGGGCTCGACTCGAGCACCTGCCTGGCGGT
GGCGCGCGCCGAGGGGCTGGAGGCGCACTGCCTCTCGGTGGACTACGGGCAGCGGCACAAGGGCGAGCTGGCGCGGGCGC
GGCGCATCGCGCGGGCGCTCGGCGCCGCCGGCCACCGCGTGGTGAAGGTGGACCTCTCCGCGTTCGGCGGCTCGGCGCTC
ACCGACGCGGCCATCGCGGTGCCGAAGGGGCGCAGCGAGGCGCGGATGGCGCGGGACATCCCGGTCACCTACGTGCCGGC
CCGCAACACCGTCATGCTCTCGCTCGCGCTCGCCCACGCCGAGGTGATCGGCGCGGAGCAGATCTTCGTGGGCGTGAACG
CCATCGACTACTCCGGCTACCCGGACTGCCGGCCGGCCTTCCTGCGGGCGTTCGAGCGCCTGGCGAAGGTCGCCACCCGG
GCCGGCGTGGAGGGGCGGCCTCTCCGGATCCGCGCGCCCCTCCTCAGGCTCTCCAAGGCGGGGATCGTCCGGCTGGGCAC
GAAGCTCCGCGTCCCCTACCGCTTGACCCTCTCGTGCTACGACCCGATCCGCGGCCGCGCCTGCGGCCGGTGCGATGCCT
GCCGCCTGCGCCGAAAGGGATTTGCCGAGGCGGGGGTGCAGGACCCAACTCAATACGCGAAGTGA

Upstream 100 bases:

>100_bases
GGTGGAGACCTACGGGGCGACCGGCGGCGCGTGCGCGCCCTGCGCGCTCCCCTGCACCGCGAGCTACGCGTTCACCGCGG
TGGCCCGCTAGGATCCTGGA

Downstream 100 bases:

>100_bases
CCGGCCGAGGGCCGGCGGAGGACCCGCAAGGATGCCGCAGATCACGAGGAAGTACCCCGGCAAGAACGCCGGTGAGATCT
ACGAGAAGGTCGACGAGGTG

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAKATSKARRAVVLLSGGLDSSTCLAVARAEGLEAHCLSVDYGQRHKGELARARRIARALGAAGHRVVKVDLSAFGGSAL
TDAAIAVPKGRSEARMARDIPVTYVPARNTVMLSLALAHAEVIGAEQIFVGVNAIDYSGYPDCRPAFLRAFERLAKVATR
AGVEGRPLRIRAPLLRLSKAGIVRLGTKLRVPYRLTLSCYDPIRGRACGRCDACRLRRKGFAEAGVQDPTQYAK

Sequences:

>Translated_234_residues
MAKATSKARRAVVLLSGGLDSSTCLAVARAEGLEAHCLSVDYGQRHKGELARARRIARALGAAGHRVVKVDLSAFGGSAL
TDAAIAVPKGRSEARMARDIPVTYVPARNTVMLSLALAHAEVIGAEQIFVGVNAIDYSGYPDCRPAFLRAFERLAKVATR
AGVEGRPLRIRAPLLRLSKAGIVRLGTKLRVPYRLTLSCYDPIRGRACGRCDACRLRRKGFAEAGVQDPTQYAK
>Mature_233_residues
AKATSKARRAVVLLSGGLDSSTCLAVARAEGLEAHCLSVDYGQRHKGELARARRIARALGAAGHRVVKVDLSAFGGSALT
DAAIAVPKGRSEARMARDIPVTYVPARNTVMLSLALAHAEVIGAEQIFVGVNAIDYSGYPDCRPAFLRAFERLAKVATRA
GVEGRPLRIRAPLLRLSKAGIVRLGTKLRVPYRLTLSCYDPIRGRACGRCDACRLRRKGFAEAGVQDPTQYAK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=226, Percent_Identity=39.3805309734513, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25096; Mature: 24964

Theoretical pI: Translated: 10.97; Mature: 10.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKATSKARRAVVLLSGGLDSSTCLAVARAEGLEAHCLSVDYGQRHKGELARARRIARAL
CCCCCCCCCEEEEEEECCCCCHHHEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GAAGHRVVKVDLSAFGGSALTDAAIAVPKGRSEARMARDIPVTYVPARNTVMLSLALAHA
CCCCCEEEEEEHHHCCCCHHCCCEEECCCCCCHHHHHHCCCEEEECCCCEEEEHHHHHHH
EVIGAEQIFVGVNAIDYSGYPDCRPAFLRAFERLAKVATRAGVEGRPLRIRAPLLRLSKA
HHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCC
GIVRLGTKLRVPYRLTLSCYDPIRGRACGRCDACRLRRKGFAEAGVQDPTQYAK
CEEEECCEEECCEEEEEEECCCCCCCCCCCCHHHHHHHCCCHHCCCCCCHHHCC
>Mature Secondary Structure 
AKATSKARRAVVLLSGGLDSSTCLAVARAEGLEAHCLSVDYGQRHKGELARARRIARAL
CCCCCCCCEEEEEEECCCCCHHHEEEHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GAAGHRVVKVDLSAFGGSALTDAAIAVPKGRSEARMARDIPVTYVPARNTVMLSLALAHA
CCCCCEEEEEEHHHCCCCHHCCCEEECCCCCCHHHHHHCCCEEEECCCCEEEEHHHHHHH
EVIGAEQIFVGVNAIDYSGYPDCRPAFLRAFERLAKVATRAGVEGRPLRIRAPLLRLSKA
HHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCC
GIVRLGTKLRVPYRLTLSCYDPIRGRACGRCDACRLRRKGFAEAGVQDPTQYAK
CEEEECCEEECCEEEEEEECCCCCCCCCCCCHHHHHHHCCCHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA