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The map label for this gene is bioC [H]

Identifier: 220918959

GI number: 220918959

Start: 4311990

End: 4312778

Strand: Direct

Name: bioC [H]

Synonym: A2cp1_3874

Alternate gene names: 220918959

Gene position: 4311990-4312778 (Clockwise)

Preceding gene: 220918958

Following gene: 220918960

Centisome position: 85.74

GC content: 81.75

Gene sequence:

>789_bases
GTGAACCGCGTCGACAAGCGCCGGGTCCAGGCCGCGTTCTCGCGCTCCGCCGCGGCGTACGACGCGCGCGCCTCGGTGCA
GCGCGAGGTGCAGGACCGCGTGCTCGCGCTGGTGGCCGAGGCCGCCCCCGACGCGCGGCGCGTGCTCGACGTCGGCGCCG
GCACCGGCGCGCTGCTGGCCCGGCTCGCCGCCGCGCGCCCCGGGCTCCGGCCCGCGGCGGTGGACCTGGCCCCGGGCATG
GCGGCGGCGGCGCGCGCGCGCCTGCCCGGCGCCGCGGTGGCGGCCGGCGACGCGGAGGCCCTGCCGTTCGGCGACGCGCG
CTTCGACCTGTTCCTCTCCACCTCGGCGTTCCAGTGGCTGCCGCGGCTCGCGCCGGCGTTCGCCGAGGCGCGCCGCGTGC
TCGCGCCGGGCGGCGTGCTCGCCGTGGCGCTGTTCGGCGCCCGCACGCTCCACGAGCTGCGCGGCGCCTGGCGCGAGGCC
GCCGGCCCGGGCCCGGGCGAGCGCACCCATCGGTTCTTCGACCGCGACGAGGTCGCCGCCGCGCTCGCCGCCGCCGGCCT
GCGGGTCCGCGCCGTCGTCGAGGAGGAGCGCCGCGAGCAGCACGCCGACGCGCGCGCGGTGCTGCGCGCGCTGAAGGAGA
TCGGCGCCACCGCGGCGGTGCCCGGCGCGCGCGGGCTGGGCGGGCGACGCGCCACGCTCGAGCTGCTCCGGCTGTACGAG
GCCCGCCACGGTGGCCCCGCCGGCGTGCCCGCCACCTGGCACGTGGTGTACGCGCTCGCGCAGCGCTGA

Upstream 100 bases:

>100_bases
CCCTGCTCCCCGGCGCCGGCCACGCGCCGCACCTCACCCGCCCGGACGAGGTCGCCGCGCTGCTCCAGGCGTTCCCCGCC
GGGGCCGGGGCGGTGGCCGC

Downstream 100 bases:

>100_bases
CCCACCTGTGGGCGCTGCACCCAGCCCGGTACCCTGCCGCCCGGCGTCCGCCGCGCTACCCTCTCGCGATGTCCCGACCG
CGCCCCTTCCCCGCCGCCGT

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNRVDKRRVQAAFSRSAAAYDARASVQREVQDRVLALVAEAAPDARRVLDVGAGTGALLARLAAARPGLRPAAVDLAPGM
AAAARARLPGAAVAAGDAEALPFGDARFDLFLSTSAFQWLPRLAPAFAEARRVLAPGGVLAVALFGARTLHELRGAWREA
AGPGPGERTHRFFDRDEVAAALAAAGLRVRAVVEEERREQHADARAVLRALKEIGATAAVPGARGLGGRRATLELLRLYE
ARHGGPAGVPATWHVVYALAQR

Sequences:

>Translated_262_residues
MNRVDKRRVQAAFSRSAAAYDARASVQREVQDRVLALVAEAAPDARRVLDVGAGTGALLARLAAARPGLRPAAVDLAPGM
AAAARARLPGAAVAAGDAEALPFGDARFDLFLSTSAFQWLPRLAPAFAEARRVLAPGGVLAVALFGARTLHELRGAWREA
AGPGPGERTHRFFDRDEVAAALAAAGLRVRAVVEEERREQHADARAVLRALKEIGATAAVPGARGLGGRRATLELLRLYE
ARHGGPAGVPATWHVVYALAQR
>Mature_262_residues
MNRVDKRRVQAAFSRSAAAYDARASVQREVQDRVLALVAEAAPDARRVLDVGAGTGALLARLAAARPGLRPAAVDLAPGM
AAAARARLPGAAVAAGDAEALPFGDARFDLFLSTSAFQWLPRLAPAFAEARRVLAPGGVLAVALFGARTLHELRGAWREA
AGPGPGERTHRFFDRDEVAAALAAAGLRVRAVVEEERREQHADARAVLRALKEIGATAAVPGARGLGGRRATLELLRLYE
ARHGGPAGVPATWHVVYALAQR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=257, Percent_Identity=33.4630350194552, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 27558; Mature: 27558

Theoretical pI: Translated: 11.74; Mature: 11.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVDKRRVQAAFSRSAAAYDARASVQREVQDRVLALVAEAAPDARRVLDVGAGTGALLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
RLAAARPGLRPAAVDLAPGMAAAARARLPGAAVAAGDAEALPFGDARFDLFLSTSAFQWL
HHHHHCCCCCCHHHHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEECCHHHHHH
PRLAPAFAEARRVLAPGGVLAVALFGARTLHELRGAWREAAGPGPGERTHRFFDRDEVAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHH
ALAAAGLRVRAVVEEERREQHADARAVLRALKEIGATAAVPGARGLGGRRATLELLRLYE
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ARHGGPAGVPATWHVVYALAQR
HHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNRVDKRRVQAAFSRSAAAYDARASVQREVQDRVLALVAEAAPDARRVLDVGAGTGALLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
RLAAARPGLRPAAVDLAPGMAAAARARLPGAAVAAGDAEALPFGDARFDLFLSTSAFQWL
HHHHHCCCCCCHHHHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEECCHHHHHH
PRLAPAFAEARRVLAPGGVLAVALFGARTLHELRGAWREAAGPGPGERTHRFFDRDEVAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHH
ALAAAGLRVRAVVEEERREQHADARAVLRALKEIGATAAVPGARGLGGRRATLELLRLYE
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ARHGGPAGVPATWHVVYALAQR
HHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]