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The map label for this gene is atoS [H]

Identifier: 220918954

GI number: 220918954

Start: 4304957

End: 4306792

Strand: Direct

Name: atoS [H]

Synonym: A2cp1_3869

Alternate gene names: 220918954

Gene position: 4304957-4306792 (Clockwise)

Preceding gene: 220918953

Following gene: 220918955

Centisome position: 85.6

GC content: 78.49

Gene sequence:

>1836_bases
ATGGCCGCCGCACCTGCCCCCTCCCCCGCGCCCGCGCGCGCCCCGCTCCGCGTGGCCGCGCCCGCCGACCTCGCGCCGGT
CGGCGAGGCGCTCGCGGCGCTCGGGATCGGCCTCACGCTGGTCGACCGCGAGATGCGGGTCCAGCTCGCGAACGACCTCG
TCCGCGACCAGGCCCCGGAGCTGTCCTGCGGCGCGGATCACTGCTTCGCGGCGCTGTGGCGCAAGGCGCAGCGCTGCTCC
GACTGCCTCCCGCTCCTCGTCTTCCGCACCGGCGAGCCGCAGGAGGGCCTGCGCGAGCGCGGCCGCCCGGGCGCGGCGCC
GGAGGCGTGGCGCGTCCGCGCGGTGCCGGTGCACGACGCCGGGGGGCGGCTGGCCTGGGTGGCGGAGTCGTTCATCCGGC
TCGCCTCGCTCGCGCCGGACCTCGCCGGGCGCGCCCCCGCGGCCGAGGCGGGCGCCGCTGCGCTGGTGGTCATCGACCGC
GAGGAGCGCATCGTCTCCTGGAGCCCGGCGGCGGCGGCGATGTTCGGCTTCCCGCTGGAGGAGGCGCTGGGCCGGCGCAT
CGATCTCATCGTCCCCGAGGACAAGGTGGACGAGGAGCGGGCGCGCGCCGCGCGGGTGGCCGCCGAGGGGCGCGCCCCGC
GCACCGAGACGGTCCGGCGCGCCCGCGACGGGCGGCGCGTCCCGGTGGCGGTCTCGGCGGTCGCGCTGCGCGACGAGGCG
GGCGCGCTGGTGGGCAGGACCTGCGTCATCGAGGACCTCTCCGCGCTGCACCAGCTCCGGGGCCAGGTGCGCGCGCAGGA
GCAGCTCCTCGCCCACATCACCCGCGAGGCCGCCGACGCGATCCTCGCCGTCGATCTCACCGGGAACGTGACCAGCTGGA
ACCGCGGCGCGGAGCAGCTCCTGGGCTGGTCCGCCGCGGAGATCACCGGCCAGCCGCTCACCCGCGTCGCGCCGGCCGGC
CCGGTGGCGCGGCTGCTGGAGCGGGCGGTGCAGCGCGGGGCGCAGCGCGGCGTCCGGATGGAGTGGCAGGACGCGCGGGG
CGCGCCGGTGCCGGTGGACGTCTCGGCGGCGGCGCTGGGCGGCGACCGCGCGCCGAGCGGCGTGGCGCTGGTGGCGCGGG
ATCTGTCGGCGCAGGTCCGGCTCGACCGGCAGCTGGTGCGCTCGGAGAAGCTCGCCATGGTGGGCAGCCTGGCGGCGGGC
CTGGCGCACGAGATCGGCACGCCGCTGAACGTGATCAGCGCGACCGCGGAGTTCCTGCTGCCCGACGCCGGCGAGGAGGC
GCGGGCCCAGCTCCGCGGCATCGTCGCCGAGACCGAGCGCATCAGCCGGCTGGTCCGCGACCTGCTCTCCTTCGCGCGCG
GCACCTCGCCCGGCAAGACCGCGGTGGCGCTGCCCGGCGCGGTCGCGCGGGTGCTGTCGCTGCTGCGCATCACGCTGGAG
CGCCGCCGCGTGCGCCTCGAGACCCGGCTCCCGGACGACCTCCCCGCGCTGCACGCCGACCCGGACGGCCTGCACCAGAT
CCTCCTCAACCTGGTGGTGAACGCCTCGCAGGCGGTGGCCGAGGGCGGGCGCGTGGTCGTGGCGGCGCGCGCGGTGGAGG
AGGACGGCGAGCGCTCGGTCCAGCTCGAGGTGCACGACGACGGTCCGGGCGTCCCGCCCGCGCTGCGCGAGCGCGTCCTC
GATCCGTTCTTCACCACCCGCGCCGAGGGCACCGGGCTCGGCCTGGCGGTGGTGGCGCGCATCGTGGCCGACCACGGCGG
CGACCTCCGGGTCGGCACCGGGCCGCTCGGCGGCGCGTCCTTCACCGTGCAGCTCCCGGCCGAGGAGGGGCGATGA

Upstream 100 bases:

>100_bases
GTGCGGGCGAGGACCGGGCTGTAGCGCCGCGGCCGGGCTGCCGCGCGCGCGACGGAATGTGCGTGCCCCGCCGCCGCGCC
CGGCGCTACCATCGCGCCGG

Downstream 100 bases:

>100_bases
GCGCGGGGACGGCGGAGGCGGCGGCGCCGCGGGCGGGCGCGCTGCGGGTGCTGGTGGTCGAGGACGACCCGCGCCTGCTC
GACATCCTCACCCGGCACCT

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MAAAPAPSPAPARAPLRVAAPADLAPVGEALAALGIGLTLVDREMRVQLANDLVRDQAPELSCGADHCFAALWRKAQRCS
DCLPLLVFRTGEPQEGLRERGRPGAAPEAWRVRAVPVHDAGGRLAWVAESFIRLASLAPDLAGRAPAAEAGAAALVVIDR
EERIVSWSPAAAAMFGFPLEEALGRRIDLIVPEDKVDEERARAARVAAEGRAPRTETVRRARDGRRVPVAVSAVALRDEA
GALVGRTCVIEDLSALHQLRGQVRAQEQLLAHITREAADAILAVDLTGNVTSWNRGAEQLLGWSAAEITGQPLTRVAPAG
PVARLLERAVQRGAQRGVRMEWQDARGAPVPVDVSAAALGGDRAPSGVALVARDLSAQVRLDRQLVRSEKLAMVGSLAAG
LAHEIGTPLNVISATAEFLLPDAGEEARAQLRGIVAETERISRLVRDLLSFARGTSPGKTAVALPGAVARVLSLLRITLE
RRRVRLETRLPDDLPALHADPDGLHQILLNLVVNASQAVAEGGRVVVAARAVEEDGERSVQLEVHDDGPGVPPALRERVL
DPFFTTRAEGTGLGLAVVARIVADHGGDLRVGTGPLGGASFTVQLPAEEGR

Sequences:

>Translated_611_residues
MAAAPAPSPAPARAPLRVAAPADLAPVGEALAALGIGLTLVDREMRVQLANDLVRDQAPELSCGADHCFAALWRKAQRCS
DCLPLLVFRTGEPQEGLRERGRPGAAPEAWRVRAVPVHDAGGRLAWVAESFIRLASLAPDLAGRAPAAEAGAAALVVIDR
EERIVSWSPAAAAMFGFPLEEALGRRIDLIVPEDKVDEERARAARVAAEGRAPRTETVRRARDGRRVPVAVSAVALRDEA
GALVGRTCVIEDLSALHQLRGQVRAQEQLLAHITREAADAILAVDLTGNVTSWNRGAEQLLGWSAAEITGQPLTRVAPAG
PVARLLERAVQRGAQRGVRMEWQDARGAPVPVDVSAAALGGDRAPSGVALVARDLSAQVRLDRQLVRSEKLAMVGSLAAG
LAHEIGTPLNVISATAEFLLPDAGEEARAQLRGIVAETERISRLVRDLLSFARGTSPGKTAVALPGAVARVLSLLRITLE
RRRVRLETRLPDDLPALHADPDGLHQILLNLVVNASQAVAEGGRVVVAARAVEEDGERSVQLEVHDDGPGVPPALRERVL
DPFFTTRAEGTGLGLAVVARIVADHGGDLRVGTGPLGGASFTVQLPAEEGR
>Mature_610_residues
AAAPAPSPAPARAPLRVAAPADLAPVGEALAALGIGLTLVDREMRVQLANDLVRDQAPELSCGADHCFAALWRKAQRCSD
CLPLLVFRTGEPQEGLRERGRPGAAPEAWRVRAVPVHDAGGRLAWVAESFIRLASLAPDLAGRAPAAEAGAAALVVIDRE
ERIVSWSPAAAAMFGFPLEEALGRRIDLIVPEDKVDEERARAARVAAEGRAPRTETVRRARDGRRVPVAVSAVALRDEAG
ALVGRTCVIEDLSALHQLRGQVRAQEQLLAHITREAADAILAVDLTGNVTSWNRGAEQLLGWSAAEITGQPLTRVAPAGP
VARLLERAVQRGAQRGVRMEWQDARGAPVPVDVSAAALGGDRAPSGVALVARDLSAQVRLDRQLVRSEKLAMVGSLAAGL
AHEIGTPLNVISATAEFLLPDAGEEARAQLRGIVAETERISRLVRDLLSFARGTSPGKTAVALPGAVARVLSLLRITLER
RRVRLETRLPDDLPALHADPDGLHQILLNLVVNASQAVAEGGRVVVAARAVEEDGERSVQLEVHDDGPGVPPALRERVLD
PFFTTRAEGTGLGLAVVARIVADHGGDLRVGTGPLGGASFTVQLPAEEGR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=340, Percent_Identity=30.8823529411765, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=38.1742738589212, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1790300, Length=350, Percent_Identity=28.8571428571429, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=32.7586206896552, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=31.390134529148, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=28.7671232876712, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=25.5905511811024, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=27.7533039647577, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=367, Percent_Identity=24.2506811989101, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786600, Length=373, Percent_Identity=22.7882037533512, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=29.1479820627803, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64464; Mature: 64333

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAPAPSPAPARAPLRVAAPADLAPVGEALAALGIGLTLVDREMRVQLANDLVRDQAPE
CCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHCCCCC
LSCGADHCFAALWRKAQRCSDCLPLLVFRTGEPQEGLRERGRPGAAPEAWRVRAVPVHDA
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCEEEEEEEEECC
GGRLAWVAESFIRLASLAPDLAGRAPAAEAGAAALVVIDREERIVSWSPAAAAMFGFPLE
CCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCEEECCCHHHHHHCCCHH
EALGRRIDLIVPEDKVDEERARAARVAAEGRAPRTETVRRARDGRRVPVAVSAVALRDEA
HHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHC
GALVGRTCVIEDLSALHQLRGQVRAQEQLLAHITREAADAILAVDLTGNVTSWNRGAEQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHH
LGWSAAEITGQPLTRVAPAGPVARLLERAVQRGAQRGVRMEWQDARGAPVPVDVSAAALG
HCCCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHCC
GDRAPSGVALVARDLSAQVRLDRQLVRSEKLAMVGSLAAGLAHEIGTPLNVISATAEFLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PDAGEEARAQLRGIVAETERISRLVRDLLSFARGTSPGKTAVALPGAVARVLSLLRITLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHH
RRRVRLETRLPDDLPALHADPDGLHQILLNLVVNASQAVAEGGRVVVAARAVEEDGERSV
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCCCCEE
QLEVHDDGPGVPPALRERVLDPFFTTRAEGTGLGLAVVARIVADHGGDLRVGTGPLGGAS
EEEEECCCCCCCHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCE
FTVQLPAEEGR
EEEEECCCCCC
>Mature Secondary Structure 
AAAPAPSPAPARAPLRVAAPADLAPVGEALAALGIGLTLVDREMRVQLANDLVRDQAPE
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHCCCCC
LSCGADHCFAALWRKAQRCSDCLPLLVFRTGEPQEGLRERGRPGAAPEAWRVRAVPVHDA
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCEEEEEEEEECC
GGRLAWVAESFIRLASLAPDLAGRAPAAEAGAAALVVIDREERIVSWSPAAAAMFGFPLE
CCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCEEECCCHHHHHHCCCHH
EALGRRIDLIVPEDKVDEERARAARVAAEGRAPRTETVRRARDGRRVPVAVSAVALRDEA
HHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHC
GALVGRTCVIEDLSALHQLRGQVRAQEQLLAHITREAADAILAVDLTGNVTSWNRGAEQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHH
LGWSAAEITGQPLTRVAPAGPVARLLERAVQRGAQRGVRMEWQDARGAPVPVDVSAAALG
HCCCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHCC
GDRAPSGVALVARDLSAQVRLDRQLVRSEKLAMVGSLAAGLAHEIGTPLNVISATAEFLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PDAGEEARAQLRGIVAETERISRLVRDLLSFARGTSPGKTAVALPGAVARVLSLLRITLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHH
RRRVRLETRLPDDLPALHADPDGLHQILLNLVVNASQAVAEGGRVVVAARAVEEDGERSV
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEECCCCCCCEE
QLEVHDDGPGVPPALRERVLDPFFTTRAEGTGLGLAVVARIVADHGGDLRVGTGPLGGAS
EEEEECCCCCCCHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCE
FTVQLPAEEGR
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]