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The map label for this gene is actP [H]

Identifier: 220918929

GI number: 220918929

Start: 4270148

End: 4271773

Strand: Direct

Name: actP [H]

Synonym: A2cp1_3843

Alternate gene names: 220918929

Gene position: 4270148-4271773 (Clockwise)

Preceding gene: 220918928

Following gene: 220918932

Centisome position: 84.9

GC content: 67.96

Gene sequence:

>1626_bases
ATGACCCACCTCGGCGTGATCCAGCAGCTCATCCTCCAGCAGGCGCAGCAGGCGGCGCCCCAGGCGACCACCACCCTCGG
GAAGCCGACCGTCGCGTCCATCGGCTTCTTCTTCCTGATCGTGGCGGTGACGCTCGTCATCACCTACTTCGCGGCGAAGA
AGACCAAGACCTCCTCCGAGTTCTACGCCGCCGGCCGCAGCGTGTCCGCGCTCCAGAACGGCTTCGCGCTCGCCGGCGAC
TACATGTCCGCCGCGTCCTTCCTCGGCATCTCCGGCATGGTCGCCCTCAAGGGCTACGACGGCATGATCTACGCCACGGG
CTGGCTCGTCGGCTGGCCGGCGCTCATGTTCCTGGTGGCGGAGCCGCTGCGCAACCTGGGCAAGTTCACGTTCGCGGACG
TGGTCGCGTTCCGCCTGCGCCAGAAGCCGGTCCGCATCGCGGCGGCCATCGGCGGCATCCTGACCGTGCTCTTCTACACC
ATCGCGCAGATGGTCGGCTCCGGCGCGCTCATCCAGCTCATGTTCGGCCTGAAGTACGAGATCGCCGAGATCATCGTCGG
CGTGGTCATGCTCGCGTACGTGCTGTTCGGCGGCATGCTCGCCACGACCTGGGTGCAGATCATCAAGGCCGGCCTGCTGC
TGTTCGGCGTGACCATCCTGACCGGGCTCGTGCTCGCGAAGTTCGGCTTCAACCCCGGCAACCTGTACCAGGCGGTGGTG
GCGCAGTACGGCCAGCCGTCGCTCGAGCCGGGCGGCTTCGTCGCGAACCCGGTGGAGGCGGTCTCCCTGGGCCTCGCGCT
CATGTTCGGCCTGCTGGGCCTGCCGCACATCCTGATGCGCTTCTACACGGTCCCGGACGCCAAGGCGGCCCGCAAGTCGG
TGCTCTACGCGACCGGCCTCATCGGCTACTTCTACCTGATCATCCCGATCGTCGGCTTCGGCGCGGCCGTGCTCACGCCG
GGCGGGCGCGCGTTCATCACCTCGGTCGACAAGGGCGGCAACATGGCCTCGCCGATCCTGGCGGAGCAGCTGCTCGGCTC
CGGCTTCCTCGGCTTCATCGCCGCGGTCGCGTTCGCGACCATCCTCGCGGTGGTGGCGGGCCTCACGCTGGCCGGCGCGT
CGGCCTACTCGCACGACATCTACGTGAACGTCATCAAGGGCGGGCACGCGACCGAGGAGGAGCAGGTCAAGGCCGCCAAG
ACCGCGACGGTGGTGTTCGGCATCTTCGCGGTGGGCCTGGGCATCCTCTTCAAGGGCCAGAACGTGGCGTTCATGGTGGG
CCTCGCGTTCGCCATCGCGGCCAGCGCGAACTTCCCGGCGCTGCTCATGTCCATCGTGTGGAAGCGCTTCACCACCATGG
GCGCGGTCTGGTCGATCCTGGTGGGCGCGTTCTCGTCCTGCATCATGATCCTGCTGTCGCCGACGGTCTGGGGCGAGGTG
TTCCACCACCTCGACGCCGCGGGCAAGCCCTACGGCATCCTGCCGTGGAAGAACCCGGCCATCTTCTCGATGACCGCCGC
GTTCGTCGCGGGCATCGTGGTGTCGCTCGTGACCGCCGACCAGACGGCGCAGGACAAGTTCGAGGACGAGAAGCTCCGCA
CGTACCTCGGCGTCGGCGCCGAGTAG

Upstream 100 bases:

>100_bases
TACTACGTGGGCTGGGCCAACAAGTCGTACGACCCCGAGGTCGAGCGGCTGAAGTCCCAGCTGAAGCGTTGACCCGGATC
GCACCAGGAGACCCGTGACC

Downstream 100 bases:

>100_bases
CGTCCCGGGCGGCGGCCCCTCCTCGACGCCGCCCTGAAGCCGCGCGGGCGGGCCCCTCCGGGCCCGCCCGTTCTTCTTTC
GCGCGCGCCGCGGCGCGCGG

Product: SSS sodium solute transporter superfamily protein

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTHLGVIQQLILQQAQQAAPQATTTLGKPTVASIGFFFLIVAVTLVITYFAAKKTKTSSEFYAAGRSVSALQNGFALAGD
YMSAASFLGISGMVALKGYDGMIYATGWLVGWPALMFLVAEPLRNLGKFTFADVVAFRLRQKPVRIAAAIGGILTVLFYT
IAQMVGSGALIQLMFGLKYEIAEIIVGVVMLAYVLFGGMLATTWVQIIKAGLLLFGVTILTGLVLAKFGFNPGNLYQAVV
AQYGQPSLEPGGFVANPVEAVSLGLALMFGLLGLPHILMRFYTVPDAKAARKSVLYATGLIGYFYLIIPIVGFGAAVLTP
GGRAFITSVDKGGNMASPILAEQLLGSGFLGFIAAVAFATILAVVAGLTLAGASAYSHDIYVNVIKGGHATEEEQVKAAK
TATVVFGIFAVGLGILFKGQNVAFMVGLAFAIAASANFPALLMSIVWKRFTTMGAVWSILVGAFSSCIMILLSPTVWGEV
FHHLDAAGKPYGILPWKNPAIFSMTAAFVAGIVVSLVTADQTAQDKFEDEKLRTYLGVGAE

Sequences:

>Translated_541_residues
MTHLGVIQQLILQQAQQAAPQATTTLGKPTVASIGFFFLIVAVTLVITYFAAKKTKTSSEFYAAGRSVSALQNGFALAGD
YMSAASFLGISGMVALKGYDGMIYATGWLVGWPALMFLVAEPLRNLGKFTFADVVAFRLRQKPVRIAAAIGGILTVLFYT
IAQMVGSGALIQLMFGLKYEIAEIIVGVVMLAYVLFGGMLATTWVQIIKAGLLLFGVTILTGLVLAKFGFNPGNLYQAVV
AQYGQPSLEPGGFVANPVEAVSLGLALMFGLLGLPHILMRFYTVPDAKAARKSVLYATGLIGYFYLIIPIVGFGAAVLTP
GGRAFITSVDKGGNMASPILAEQLLGSGFLGFIAAVAFATILAVVAGLTLAGASAYSHDIYVNVIKGGHATEEEQVKAAK
TATVVFGIFAVGLGILFKGQNVAFMVGLAFAIAASANFPALLMSIVWKRFTTMGAVWSILVGAFSSCIMILLSPTVWGEV
FHHLDAAGKPYGILPWKNPAIFSMTAAFVAGIVVSLVTADQTAQDKFEDEKLRTYLGVGAE
>Mature_540_residues
THLGVIQQLILQQAQQAAPQATTTLGKPTVASIGFFFLIVAVTLVITYFAAKKTKTSSEFYAAGRSVSALQNGFALAGDY
MSAASFLGISGMVALKGYDGMIYATGWLVGWPALMFLVAEPLRNLGKFTFADVVAFRLRQKPVRIAAAIGGILTVLFYTI
AQMVGSGALIQLMFGLKYEIAEIIVGVVMLAYVLFGGMLATTWVQIIKAGLLLFGVTILTGLVLAKFGFNPGNLYQAVVA
QYGQPSLEPGGFVANPVEAVSLGLALMFGLLGLPHILMRFYTVPDAKAARKSVLYATGLIGYFYLIIPIVGFGAAVLTPG
GRAFITSVDKGGNMASPILAEQLLGSGFLGFIAAVAFATILAVVAGLTLAGASAYSHDIYVNVIKGGHATEEEQVKAAKT
ATVVFGIFAVGLGILFKGQNVAFMVGLAFAIAASANFPALLMSIVWKRFTTMGAVWSILVGAFSSCIMILLSPTVWGEVF
HHLDAAGKPYGILPWKNPAIFSMTAAFVAGIVVSLVTADQTAQDKFEDEKLRTYLGVGAE

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=514, Percent_Identity=25.4863813229572, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1790503, Length=502, Percent_Identity=52.390438247012, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1787251, Length=437, Percent_Identity=24.9427917620137, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082237, Length=432, Percent_Identity=22.4537037037037, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57004; Mature: 56873

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure 
THLGVIQQLILQQAQQAAPQATTTLGKPTVASIGFFFLIVAVTLVITYFAAKKTKTSSE
CHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FYAAGRSVSALQNGFALAGDYMSAASFLGISGMVALKGYDGMIYATGWLVGWPALMFLVA
HHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHHHHH
EPLRNLGKFTFADVVAFRLRQKPVRIAAAIGGILTVLFYTIAQMVGSGALIQLMFGLKYE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAEIIVGVVMLAYVLFGGMLATTWVQIIKAGLLLFGVTILTGLVLAKFGFNPGNLYQAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AQYGQPSLEPGGFVANPVEAVSLGLALMFGLLGLPHILMRFYTVPDAKAARKSVLYATGL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IGYFYLIIPIVGFGAAVLTPGGRAFITSVDKGGNMASPILAEQLLGSGFLGFIAAVAFAT
HHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
ILAVVAGLTLAGASAYSHDIYVNVIKGGHATEEEQVKAAKTATVVFGIFAVGLGILFKGQ
HHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVAFMVGLAFAIAASANFPALLMSIVWKRFTTMGAVWSILVGAFSSCIMILLSPTVWGEV
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHHLDAAGKPYGILPWKNPAIFSMTAAFVAGIVVSLVTADQTAQDKFEDEKLRTYLGVGA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]