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The map label for this gene is pgpA [H]

Identifier: 220918839

GI number: 220918839

Start: 4169209

End: 4169796

Strand: Direct

Name: pgpA [H]

Synonym: A2cp1_3751

Alternate gene names: 220918839

Gene position: 4169209-4169796 (Clockwise)

Preceding gene: 220918838

Following gene: 220918840

Centisome position: 82.9

GC content: 74.66

Gene sequence:

>588_bases
ATGCCCGCGCCGGGCGCGTCCTCCCCCGGCCTCCTCTCCCGCCTCCGCCGCCGCGGCCTGAAGCGCGGCCCGAGCCCGAA
GGGCCCGCCGGGCCCGGCGGTGCTGTTCGCCGCGTGGGGCCCGTGCGGCTACGCGCCGGTCGCGCCCGGCACGTTCGGCA
CGCTCGGCGCCATCCCGCTCTACTGGGCGCTCACCTGGCTCACCTGGCCCGCGTACCTCGCGGTCACCGCGGCGCTCACC
GCGCTCGCCATGGTGGCGGCCCAGCGCGCCGGCCGTTACTGGGGAGTGGCCGATGCCTCGCCCATCGTGGTGGACGAGGT
GGCCGGGTACCTCGTGACCATGGCGCTCGTCCCGTTCTCCTGGCCCGCGGCGATTGCCGGCTTCGTGCTGTTCCGGATCT
TCGACGTGCTGAAGCCCTGGCCGGCCTCCGCGTTCGACCGCGTGAAGAACGGCTTCGGCGTGGTGATGGACGACGTGGCG
GCCGGGGTGTTCGCCTGGTGCACGCTGCAGTTCGTGCAGCTCGCGCTGCGGCTCCTCGCCGGCTGCGGGACCGTGTTCCA
CTGGTGGTGCGTGGAGGTGGGGTCGTGA

Upstream 100 bases:

>100_bases
GCTCGAGCCGGGCCCCGAGGACGTGGACGGGGACAAGGCGGAGCAGGACGAGTACATCTAGCGCGTGACCACGCCGCCCT
CGCCCGCGCCCGGCCCGGCC

Downstream 100 bases:

>100_bases
TGCAGGTGGAGATCCTCGCGACCGGCGACGAGCTGCTCACCGGCCAGGTGGTGGACACGAACTCCCCGTGGCTGATGGAC
CGGCTGTGGGACCTCGGCCT

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPAPGASSPGLLSRLRRRGLKRGPSPKGPPGPAVLFAAWGPCGYAPVAPGTFGTLGAIPLYWALTWLTWPAYLAVTAALT
ALAMVAAQRAGRYWGVADASPIVVDEVAGYLVTMALVPFSWPAAIAGFVLFRIFDVLKPWPASAFDRVKNGFGVVMDDVA
AGVFAWCTLQFVQLALRLLAGCGTVFHWWCVEVGS

Sequences:

>Translated_195_residues
MPAPGASSPGLLSRLRRRGLKRGPSPKGPPGPAVLFAAWGPCGYAPVAPGTFGTLGAIPLYWALTWLTWPAYLAVTAALT
ALAMVAAQRAGRYWGVADASPIVVDEVAGYLVTMALVPFSWPAAIAGFVLFRIFDVLKPWPASAFDRVKNGFGVVMDDVA
AGVFAWCTLQFVQLALRLLAGCGTVFHWWCVEVGS
>Mature_194_residues
PAPGASSPGLLSRLRRRGLKRGPSPKGPPGPAVLFAAWGPCGYAPVAPGTFGTLGAIPLYWALTWLTWPAYLAVTAALTA
LAMVAAQRAGRYWGVADASPIVVDEVAGYLVTMALVPFSWPAAIAGFVLFRIFDVLKPWPASAFDRVKNGFGVVMDDVAA
GVFAWCTLQFVQLALRLLAGCGTVFHWWCVEVGS

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=132, Percent_Identity=40.1515151515151, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 20649; Mature: 20518

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPGASSPGLLSRLRRRGLKRGPSPKGPPGPAVLFAAWGPCGYAPVAPGTFGTLGAIPL
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
YWALTWLTWPAYLAVTAALTALAMVAAQRAGRYWGVADASPIVVDEVAGYLVTMALVPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
WPAAIAGFVLFRIFDVLKPWPASAFDRVKNGFGVVMDDVAAGVFAWCTLQFVQLALRLLA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCGTVFHWWCVEVGS
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAPGASSPGLLSRLRRRGLKRGPSPKGPPGPAVLFAAWGPCGYAPVAPGTFGTLGAIPL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH
YWALTWLTWPAYLAVTAALTALAMVAAQRAGRYWGVADASPIVVDEVAGYLVTMALVPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
WPAAIAGFVLFRIFDVLKPWPASAFDRVKNGFGVVMDDVAAGVFAWCTLQFVQLALRLLA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCGTVFHWWCVEVGS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]