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The map label for this gene is yafV [C]

Identifier: 220918803

GI number: 220918803

Start: 4133076

End: 4133888

Strand: Direct

Name: yafV [C]

Synonym: A2cp1_3715

Alternate gene names: 220918803

Gene position: 4133076-4133888 (Clockwise)

Preceding gene: 220918794

Following gene: 220918814

Centisome position: 82.18

GC content: 73.06

Gene sequence:

>813_bases
ATGGCTGCTCCCACCTACCTGCTCGGCGCGGTGCAGATGACGTCCACCGCGGACCGCTCCCGGAATCTCGAGACCGCGGT
CCGGCTGGTGAACGAGGCGGCGGACCTCGGCGCCCGGCTCATCGGCCTGCCCGAGAACTTCGCGTACATGGGGCCCGAGG
AGGGCCGCCGGGCCGGTGCCGAGACGCTGGAGGGGCCCACGGTGAGGGCGCTCTCCGAGGTGGCGCGGCGGCGCGGCGTG
TACGTGCTGGCCGGGTCGATCGCGGAGAAGGTGGACGACCCGGGCAAGACCGCCAACACGAGCGTGCTCATCGCGGACGA
CGGCCGGGTGGCGGCCGCGTACCGCAAGATCCACCTGTTCGACGTGTCCATCCCCGACGGCGCGCGCTACGCCGAGTCCG
AGGTGGTGGTGCCGGGCGACAAGGTCGTGATCGCGCCCACGCCGCTCGGGCGCGTCGGGCTCACCGTCTGCTACGACCTG
CGCTTCCCGGAGCTGTACCGGAAGCTGGCCGGGCTCGGCGCCGAGGTGATCACCATCCCCGCCGCGTTCACGCTGTTCAC
CGGCAAGGACCACTGGGAGGTCCTGCTCCGCGCGCGCGCCATCGAGAACCTGGCCTACGTGATGGCGCCGGCGCAGGTGG
GCCGCCACTCCGCCAGCCGGCAGACGTTCGGCAACGCGATGATCGTGGACCCGTGGGGCGTGGTCCTCGCCCGCTGCCCC
GACGGCGAGGGCGTGTGCGTGGCCCCGTTCCGCCGCGAGCGGCTGGAGCAGGTGCGCCAGGAGCTCCCGGCGCTGAAGCA
CCGGAAGCTCTAG

Upstream 100 bases:

>100_bases
AGGGACCCGGCGAGCAGGGTGGGGCGGGGCGCAGCCCCGTCAGATCGTCCCGCGCCCCCCGGGCGTGCCAGGGCCCGCCC
GGGAATGCTAAGGAGAGCCC

Downstream 100 bases:

>100_bases
GCGAACGCCTAAAACACGAACATCAGGCCCCCGGCCATCGCCAGGTCCTTGTTCGACAGGTCCCAGCTCTTCTTCGAGCC
GAAGTCGTCCACCTTCGCCT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAAPTYLLGAVQMTSTADRSRNLETAVRLVNEAADLGARLIGLPENFAYMGPEEGRRAGAETLEGPTVRALSEVARRRGV
YVLAGSIAEKVDDPGKTANTSVLIADDGRVAAAYRKIHLFDVSIPDGARYAESEVVVPGDKVVIAPTPLGRVGLTVCYDL
RFPELYRKLAGLGAEVITIPAAFTLFTGKDHWEVLLRARAIENLAYVMAPAQVGRHSASRQTFGNAMIVDPWGVVLARCP
DGEGVCVAPFRRERLEQVRQELPALKHRKL

Sequences:

>Translated_270_residues
MAAPTYLLGAVQMTSTADRSRNLETAVRLVNEAADLGARLIGLPENFAYMGPEEGRRAGAETLEGPTVRALSEVARRRGV
YVLAGSIAEKVDDPGKTANTSVLIADDGRVAAAYRKIHLFDVSIPDGARYAESEVVVPGDKVVIAPTPLGRVGLTVCYDL
RFPELYRKLAGLGAEVITIPAAFTLFTGKDHWEVLLRARAIENLAYVMAPAQVGRHSASRQTFGNAMIVDPWGVVLARCP
DGEGVCVAPFRRERLEQVRQELPALKHRKL
>Mature_269_residues
AAPTYLLGAVQMTSTADRSRNLETAVRLVNEAADLGARLIGLPENFAYMGPEEGRRAGAETLEGPTVRALSEVARRRGVY
VLAGSIAEKVDDPGKTANTSVLIADDGRVAAAYRKIHLFDVSIPDGARYAESEVVVPGDKVVIAPTPLGRVGLTVCYDLR
FPELYRKLAGLGAEVITIPAAFTLFTGKDHWEVLLRARAIENLAYVMAPAQVGRHSASRQTFGNAMIVDPWGVVLARCPD
GEGVCVAPFRRERLEQVRQELPALKHRKL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=269, Percent_Identity=44.6096654275093, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI297632348, Length=269, Percent_Identity=44.6096654275093, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI5031947, Length=269, Percent_Identity=44.6096654275093, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=36.2962962962963, Blast_Score=190, Evalue=9e-49,
Organism=Homo sapiens, GI297632346, Length=193, Percent_Identity=41.4507772020725, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1786412, Length=234, Percent_Identity=29.4871794871795, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556280, Length=274, Percent_Identity=37.5912408759124, Blast_Score=203, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17533173, Length=195, Percent_Identity=28.7179487179487, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=31.1258278145695, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323383, Length=267, Percent_Identity=33.7078651685393, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17933642, Length=261, Percent_Identity=39.8467432950192, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI21355835, Length=265, Percent_Identity=34.3396226415094, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29259; Mature: 29128

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPTYLLGAVQMTSTADRSRNLETAVRLVNEAADLGARLIGLPENFAYMGPEEGRRAGA
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHCCC
ETLEGPTVRALSEVARRRGVYVLAGSIAEKVDDPGKTANTSVLIADDGRVAAAYRKIHLF
HHCCCCHHHHHHHHHHHCCEEEEECHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEEEEE
DVSIPDGARYAESEVVVPGDKVVIAPTPLGRVGLTVCYDLRFPELYRKLAGLGAEVITIP
EEECCCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEC
AAFTLFTGKDHWEVLLRARAIENLAYVMAPAQVGRHSASRQTFGNAMIVDPWGVVLARCP
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHCCCEEEECCHHEEEEECC
DGEGVCVAPFRRERLEQVRQELPALKHRKL
CCCCEEECCHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure 
AAPTYLLGAVQMTSTADRSRNLETAVRLVNEAADLGARLIGLPENFAYMGPEEGRRAGA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHCCC
ETLEGPTVRALSEVARRRGVYVLAGSIAEKVDDPGKTANTSVLIADDGRVAAAYRKIHLF
HHCCCCHHHHHHHHHHHCCEEEEECHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEEEEE
DVSIPDGARYAESEVVVPGDKVVIAPTPLGRVGLTVCYDLRFPELYRKLAGLGAEVITIP
EEECCCCCCCCCCEEEECCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEC
AAFTLFTGKDHWEVLLRARAIENLAYVMAPAQVGRHSASRQTFGNAMIVDPWGVVLARCP
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHCCCEEEECCHHEEEEECC
DGEGVCVAPFRRERLEQVRQELPALKHRKL
CCCCEEECCHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]