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The map label for this gene is 220918680

Identifier: 220918680

GI number: 220918680

Start: 4006723

End: 4007697

Strand: Reverse

Name: 220918680

Synonym: A2cp1_3588

Alternate gene names: NA

Gene position: 4007697-4006723 (Counterclockwise)

Preceding gene: 220918683

Following gene: 220918678

Centisome position: 79.69

GC content: 79.18

Gene sequence:

>975_bases
ATGCCTCGGCGCGTCCTCCTCGTCTCACACCCCGACTGCCAGGCCCACGATCCCGGCCCCGGACACCCGGAGCGCCTGGC
GCGGCTCGAGGCCGCGCTGGAGGCGCTCGCGGAGGATGCCGCGCTCGGGCCGGACGTGCTGGTGCGCGTCGAGGCGGCGC
GGGCGACCGAGCAGGCGCTGCTGCGCGTCCACACCCCCGGGCACCTCGCCCGCGTGCGCGCCCACGTGGAGGCGGCGGCG
CGCACCCGGATGCTCGACTGGCTCGAGCCGGAGACGCCGGTGTCGGCGGGCTCCTGGCGCGCGGCGGTGGCCGCCGCCGG
CGCGGCCATCGAGGCGGCCGAGCGGGTGGCGCGCGGCGAGGCGGGGGCGGCGTTCGCGCTGGTCCGGCCGCCGGGCCACC
ACGCCTGGGCGGACCGCGGCGGCGGGTACTGCCTGCTCAACAACGTCGCGATCGCGGCGCGCGCGGTCCAGGCGGCGGGG
CTGGCGCGGCGGGTGCTCGTGGTGGACTGGGACGTCCACCACTGCGACGGCACGCAGTCCATCTTCTGGGAGGACCCCGC
CGTCTACGTGCTCTCGGTGCACCTGTGGCCGCACTACCCGCACACCGGCGCGCCGGAGGAGCGCGGCGCCGGCGCGGGCG
AGGGGACCACCCGCAACGTGGCGGTGCCGCACGGCACGCGCGCCCCCGAGCAGCGTCGGCTCTTCGAGGAGGGGCTGGCG
GCGGCGCTCGCCGAGTTCCAGCCGGACCTGGTGCTGCTCTCGGCCGGCTTCGACCCGCTGGAGGGCGACCCGGAGGGCGG
CCTGCACCTCGAGCCCGCCGACCTGCACGCGATGACGCGGACGCTGCTGGCGCGGTGCGCCGCCGCGGGCTGCGACCGGA
TCGCGGCGGTGCTGGAGGGCGGCTACGTCCCGCCGCGGCTGGGCCAGGGCGTGGTGCAGGTGGTGCGGGCGCTGGCGGGG
CTGCCGGCGGCCTAG

Upstream 100 bases:

>100_bases
TGGGACCGGCGGAGGGCCAGTGTGACGGACAGTGAACTGGGCGCACGGGCCGGCCGGGGTTCCCCCGCCCGCTCGCCGGG
AGTATGGTGCGCGCCGAACC

Downstream 100 bases:

>100_bases
CGCGGGCGCGCGCCGAAGCGGATGAGGTCGCGCTCGCCGCGCCCGAACGCGGCCAGCAGCGCCGCCGGGCCGTGGGCCTG
CGCCTCCGCGAGCTCATGCG

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPRRVLLVSHPDCQAHDPGPGHPERLARLEAALEALAEDAALGPDVLVRVEAARATEQALLRVHTPGHLARVRAHVEAAA
RTRMLDWLEPETPVSAGSWRAAVAAAGAAIEAAERVARGEAGAAFALVRPPGHHAWADRGGGYCLLNNVAIAARAVQAAG
LARRVLVVDWDVHHCDGTQSIFWEDPAVYVLSVHLWPHYPHTGAPEERGAGAGEGTTRNVAVPHGTRAPEQRRLFEEGLA
AALAEFQPDLVLLSAGFDPLEGDPEGGLHLEPADLHAMTRTLLARCAAAGCDRIAAVLEGGYVPPRLGQGVVQVVRALAG
LPAA

Sequences:

>Translated_324_residues
MPRRVLLVSHPDCQAHDPGPGHPERLARLEAALEALAEDAALGPDVLVRVEAARATEQALLRVHTPGHLARVRAHVEAAA
RTRMLDWLEPETPVSAGSWRAAVAAAGAAIEAAERVARGEAGAAFALVRPPGHHAWADRGGGYCLLNNVAIAARAVQAAG
LARRVLVVDWDVHHCDGTQSIFWEDPAVYVLSVHLWPHYPHTGAPEERGAGAGEGTTRNVAVPHGTRAPEQRRLFEEGLA
AALAEFQPDLVLLSAGFDPLEGDPEGGLHLEPADLHAMTRTLLARCAAAGCDRIAAVLEGGYVPPRLGQGVVQVVRALAG
LPAA
>Mature_323_residues
PRRVLLVSHPDCQAHDPGPGHPERLARLEAALEALAEDAALGPDVLVRVEAARATEQALLRVHTPGHLARVRAHVEAAAR
TRMLDWLEPETPVSAGSWRAAVAAAGAAIEAAERVARGEAGAAFALVRPPGHHAWADRGGGYCLLNNVAIAARAVQAAGL
ARRVLVVDWDVHHCDGTQSIFWEDPAVYVLSVHLWPHYPHTGAPEERGAGAGEGTTRNVAVPHGTRAPEQRRLFEEGLAA
ALAEFQPDLVLLSAGFDPLEGDPEGGLHLEPADLHAMTRTLLARCAAAGCDRIAAVLEGGYVPPRLGQGVVQVVRALAGL
PAA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=318, Percent_Identity=33.6477987421384, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI20070354, Length=332, Percent_Identity=36.144578313253, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI153085395, Length=217, Percent_Identity=40.5529953917051, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI148539870, Length=214, Percent_Identity=42.0560747663551, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169234807, Length=214, Percent_Identity=42.0560747663551, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI30795202, Length=217, Percent_Identity=39.1705069124424, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI30795204, Length=217, Percent_Identity=39.1705069124424, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI17158039, Length=211, Percent_Identity=39.3364928909953, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI62750349, Length=214, Percent_Identity=39.7196261682243, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI62750347, Length=214, Percent_Identity=39.7196261682243, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226529806, Length=330, Percent_Identity=33.6363636363636, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI217272877, Length=308, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI209862883, Length=302, Percent_Identity=27.4834437086093, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13128860, Length=275, Percent_Identity=23.6363636363636, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI293336691, Length=278, Percent_Identity=23.021582733813, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI8923769, Length=268, Percent_Identity=26.1194029850746, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI13128862, Length=278, Percent_Identity=25.1798561151079, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI262073088, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=317, Percent_Identity=35.0157728706625, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=311, Percent_Identity=34.0836012861736, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=311, Percent_Identity=34.0836012861736, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17537347, Length=331, Percent_Identity=33.5347432024169, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI193209491, Length=233, Percent_Identity=36.0515021459227, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25154020, Length=308, Percent_Identity=30.1948051948052, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25154022, Length=308, Percent_Identity=29.8701298701299, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508561, Length=258, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534739, Length=276, Percent_Identity=25, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=221, Percent_Identity=23.5294117647059, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=34.0557275541796, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323999, Length=278, Percent_Identity=28.4172661870504, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321244, Length=238, Percent_Identity=23.9495798319328, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325141, Length=286, Percent_Identity=24.1258741258741, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=310, Percent_Identity=33.2258064516129, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642142, Length=310, Percent_Identity=33.2258064516129, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642146, Length=310, Percent_Identity=33.2258064516129, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642144, Length=310, Percent_Identity=33.2258064516129, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24641720, Length=328, Percent_Identity=35.0609756097561, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281360799, Length=328, Percent_Identity=35.0609756097561, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281360801, Length=328, Percent_Identity=35.0609756097561, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24644244, Length=280, Percent_Identity=26.4285714285714, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24657891, Length=278, Percent_Identity=24.4604316546763, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649807, Length=265, Percent_Identity=27.5471698113208, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34133; Mature: 34002

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRRVLLVSHPDCQAHDPGPGHPERLARLEAALEALAEDAALGPDVLVRVEAARATEQAL
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LRVHTPGHLARVRAHVEAAARTRMLDWLEPETPVSAGSWRAAVAAAGAAIEAAERVARGE
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
AGAAFALVRPPGHHAWADRGGGYCLLNNVAIAARAVQAAGLARRVLVVDWDVHHCDGTQS
CCCEEEEECCCCCCCHHCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEEECEEECCCCCC
IFWEDPAVYVLSVHLWPHYPHTGAPEERGAGAGEGTTRNVAVPHGTRAPEQRRLFEEGLA
EEECCCEEEEEEEEECCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHH
AALAEFQPDLVLLSAGFDPLEGDPEGGLHLEPADLHAMTRTLLARCAAAGCDRIAAVLEG
HHHHHCCCCEEEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYVPPRLGQGVVQVVRALAGLPAA
CCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRRVLLVSHPDCQAHDPGPGHPERLARLEAALEALAEDAALGPDVLVRVEAARATEQAL
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
LRVHTPGHLARVRAHVEAAARTRMLDWLEPETPVSAGSWRAAVAAAGAAIEAAERVARGE
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
AGAAFALVRPPGHHAWADRGGGYCLLNNVAIAARAVQAAGLARRVLVVDWDVHHCDGTQS
CCCEEEEECCCCCCCHHCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEEECEEECCCCCC
IFWEDPAVYVLSVHLWPHYPHTGAPEERGAGAGEGTTRNVAVPHGTRAPEQRRLFEEGLA
EEECCCEEEEEEEEECCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHH
AALAEFQPDLVLLSAGFDPLEGDPEGGLHLEPADLHAMTRTLLARCAAAGCDRIAAVLEG
HHHHHCCCCEEEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYVPPRLGQGVVQVVRALAGLPAA
CCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]