Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 220918589

GI number: 220918589

Start: 3910569

End: 3912290

Strand: Direct

Name: csd [H]

Synonym: A2cp1_3497

Alternate gene names: 220918589

Gene position: 3910569-3912290 (Clockwise)

Preceding gene: 220918587

Following gene: 220918593

Centisome position: 77.76

GC content: 75.67

Gene sequence:

>1722_bases
ATGCCCTTCGAACAGGTGGCCGCGCGCGTGCGCCGCGGCGAGATCGGCCGGCGTACCTTCGTCTGCACCCCCTTCGGGCG
CAGGCTCGTGACCTACGCGGACCTGACCGCCACCGGGCGGGCGCTCGCGCCGGTGGAGGCGCTGGTCGCCGCGGCGCGGC
CGCTCTACGCGAACACGCACACCGCCATCTCGACCACCGGGCGGGTGACCACCCGCCTGCGCGAGTCGGCGCGGGAGGCG
ATCGCACGCGCGGTCAACGCGGGCCCGGACGACGTGGTGCTGTTCGTGGGGAGCGGCGCCACGTCCGCCGTCAACAAGCT
CGTCGGCCTGCTGGGCCTGCGCATCTCCGAGCCGCTGGAGCGCGCGTACGGCCTCTCGCGGCACGTCCCGCCGGACGAGC
GGCCGGTCGTGCTGGTCTCGCCCTACGAGCACCACTCGAACCAGCTCCCCTGGCTCGAGTCGGTGGCCGAGGTGGTGGAG
GTGGACCTGGACGGCGACGGCCAGGTGGACCTGGCCGACCTCGACCGGAAGGCGGCCCGGTACGCAGGGCGCCCGCTGCG
CGTGGGCGCGTTCTCGGCGGGCTCCAACGTGACCGGCGCGCTCACCGACGTGCGCGCGGTCGCGCGCGTGCTCCACCGTC
GCGGGTTCCTGGCCTGCGCCGACTACGCCGCGGCCGGCCCGTACGTCCCCATCGACATGCACCCGGCCGACGCGGACGAG
CGGCTCGACGCCATCGTCGTGTCCACCCACAAGTTCGCGGGCGGGCCGGAGGGCTCGGGGATCCTGGTGGCGCACCGCGC
GCTGTTCCGCAGCCGCACGCCCGAGCGGCCCGGCGGCGGCACCGTCGAGTACGTGGCGGCGTTCGACCGGCTCTCGGTGG
ACTACACCGAGCGGCTCGCGGAGCGCGAGGAGGGCGGTACGCCCGACATCCTCGGCGACGTGCGCGCGGGGCTCGCGTTC
CTCGTGAAGGAGGCGCTCGGCCCCGAGGCGATCCTCGCGCACGAGACCGCGCTCGCCGAGCGCGCCATGGCGCGCCTGCG
CCGGCACCCCCGCATCCGGCTCTACGGCCCGGCGCACGGGCCCCGCCTGCCCATCCTCTCCTTCAACGTGGAGGGGCTGC
ACCACGACTTCGTGTCGGCGCTGCTCGACCACCTGTTCGGCATCCAGAACCGCGCCGGGTGCTCCTGCGCCGGACCGTAC
GGGCACCGGCTGCTGGGCATCGGCCCGGAGCGCTCGTCCGAGCTCCGCCGCGCCATCGCGCTCGGCGTGCTGGCGCTGAA
GCCGGGCTGGGTCCGGATCTCCCTGCCCTACACCGCCACCGAGGACGAGATCGAATTCCTGCTCGAGGCGGTGGAGCTGG
TGGCGGATCACGGCGAGGCGTTCCTGCCGCTCTACCGGCTGGGCTGGGGCGACGGGATGTGGCGGCCGCTGGACGCTGCG
CCGGCGGATCCCGTCGCGGTGGAGCTGACGGTGGAGGCGGTGCGCGCGGCGCTCCTGCGCGAGGAGCCGCCGGCGCCCCC
GGCGGAGGAGCCGGTGACCGAGGCCCAGGCGGCGGCGCTCCGCCGCGACTACCTGGACGAGGCGCGGCGCCTCGCGACGG
AGCTCGAGGCCCGCCACGCCGGCCAGCCGCTGCGGTGGAACCCGCCCACCGGTGACGCGTTCGTGGACCGGCTGGTCTGG
TTCCGCTACGTGCACGCGGACCCTTCGGCTCCGGCGGCCTAG

Upstream 100 bases:

>100_bases
CCCGTTCTTCGGGACCGCACTCAGGTTTCGCACCGGCGGGGCTCCCCCGCCCGCCCGCGCTCTTGTCGGGCGTCCCGCAC
CCCGCTACAAGCCGGGACCC

Downstream 100 bases:

>100_bases
GGCCGCCTACGCTCAGGGTGAGCGGGCCTACATCCGGATCGACGCGCTCATCCCGAGCGTAGCGCCGCGCGAGCGGCGCG
GAGTCGAGGGACCTACGCCG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MPFEQVAARVRRGEIGRRTFVCTPFGRRLVTYADLTATGRALAPVEALVAAARPLYANTHTAISTTGRVTTRLRESAREA
IARAVNAGPDDVVLFVGSGATSAVNKLVGLLGLRISEPLERAYGLSRHVPPDERPVVLVSPYEHHSNQLPWLESVAEVVE
VDLDGDGQVDLADLDRKAARYAGRPLRVGAFSAGSNVTGALTDVRAVARVLHRRGFLACADYAAAGPYVPIDMHPADADE
RLDAIVVSTHKFAGGPEGSGILVAHRALFRSRTPERPGGGTVEYVAAFDRLSVDYTERLAEREEGGTPDILGDVRAGLAF
LVKEALGPEAILAHETALAERAMARLRRHPRIRLYGPAHGPRLPILSFNVEGLHHDFVSALLDHLFGIQNRAGCSCAGPY
GHRLLGIGPERSSELRRAIALGVLALKPGWVRISLPYTATEDEIEFLLEAVELVADHGEAFLPLYRLGWGDGMWRPLDAA
PADPVAVELTVEAVRAALLREEPPAPPAEEPVTEAQAAALRRDYLDEARRLATELEARHAGQPLRWNPPTGDAFVDRLVW
FRYVHADPSAPAA

Sequences:

>Translated_573_residues
MPFEQVAARVRRGEIGRRTFVCTPFGRRLVTYADLTATGRALAPVEALVAAARPLYANTHTAISTTGRVTTRLRESAREA
IARAVNAGPDDVVLFVGSGATSAVNKLVGLLGLRISEPLERAYGLSRHVPPDERPVVLVSPYEHHSNQLPWLESVAEVVE
VDLDGDGQVDLADLDRKAARYAGRPLRVGAFSAGSNVTGALTDVRAVARVLHRRGFLACADYAAAGPYVPIDMHPADADE
RLDAIVVSTHKFAGGPEGSGILVAHRALFRSRTPERPGGGTVEYVAAFDRLSVDYTERLAEREEGGTPDILGDVRAGLAF
LVKEALGPEAILAHETALAERAMARLRRHPRIRLYGPAHGPRLPILSFNVEGLHHDFVSALLDHLFGIQNRAGCSCAGPY
GHRLLGIGPERSSELRRAIALGVLALKPGWVRISLPYTATEDEIEFLLEAVELVADHGEAFLPLYRLGWGDGMWRPLDAA
PADPVAVELTVEAVRAALLREEPPAPPAEEPVTEAQAAALRRDYLDEARRLATELEARHAGQPLRWNPPTGDAFVDRLVW
FRYVHADPSAPAA
>Mature_572_residues
PFEQVAARVRRGEIGRRTFVCTPFGRRLVTYADLTATGRALAPVEALVAAARPLYANTHTAISTTGRVTTRLRESAREAI
ARAVNAGPDDVVLFVGSGATSAVNKLVGLLGLRISEPLERAYGLSRHVPPDERPVVLVSPYEHHSNQLPWLESVAEVVEV
DLDGDGQVDLADLDRKAARYAGRPLRVGAFSAGSNVTGALTDVRAVARVLHRRGFLACADYAAAGPYVPIDMHPADADER
LDAIVVSTHKFAGGPEGSGILVAHRALFRSRTPERPGGGTVEYVAAFDRLSVDYTERLAEREEGGTPDILGDVRAGLAFL
VKEALGPEAILAHETALAERAMARLRRHPRIRLYGPAHGPRLPILSFNVEGLHHDFVSALLDHLFGIQNRAGCSCAGPYG
HRLLGIGPERSSELRRAIALGVLALKPGWVRISLPYTATEDEIEFLLEAVELVADHGEAFLPLYRLGWGDGMWRPLDAAP
ADPVAVELTVEAVRAALLREEPPAPPAEEPVTEAQAAALRRDYLDEARRLATELEARHAGQPLRWNPPTGDAFVDRLVWF
RYVHADPSAPAA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789175, Length=394, Percent_Identity=30.2030456852792, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787970, Length=380, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=492, Percent_Identity=35.3658536585366, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 62017; Mature: 61886

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00018 EF_HAND_1 ; PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFEQVAARVRRGEIGRRTFVCTPFGRRLVTYADLTATGRALAPVEALVAAARPLYANTH
CCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECHHCCCCHHHHHHHHHHHCCCCCCCCC
TAISTTGRVTTRLRESAREAIARAVNAGPDDVVLFVGSGATSAVNKLVGLLGLRISEPLE
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RAYGLSRHVPPDERPVVLVSPYEHHSNQLPWLESVAEVVEVDLDGDGQVDLADLDRKAAR
HHCCCCCCCCCCCCCEEEECCCHHCCCCCCHHHHHHHHHEECCCCCCCEEHHHHHHHHHH
YAGRPLRVGAFSAGSNVTGALTDVRAVARVLHRRGFLACADYAAAGPYVPIDMHPADADE
HCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEEEEECCCCCCHH
RLDAIVVSTHKFAGGPEGSGILVAHRALFRSRTPERPGGGTVEYVAAFDRLSVDYTERLA
HHCEEEEECHHCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
EREEGGTPDILGDVRAGLAFLVKEALGPEAILAHETALAERAMARLRRHPRIRLYGPAHG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
PRLPILSFNVEGLHHDFVSALLDHLFGIQNRAGCSCAGPYGHRLLGIGPERSSELRRAIA
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHH
LGVLALKPGWVRISLPYTATEDEIEFLLEAVELVADHGEAFLPLYRLGWGDGMWRPLDAA
HHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCC
PADPVAVELTVEAVRAALLREEPPAPPAEEPVTEAQAAALRRDYLDEARRLATELEARHA
CCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQPLRWNPPTGDAFVDRLVWFRYVHADPSAPAA
CCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
PFEQVAARVRRGEIGRRTFVCTPFGRRLVTYADLTATGRALAPVEALVAAARPLYANTH
CHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECHHCCCCHHHHHHHHHHHCCCCCCCCC
TAISTTGRVTTRLRESAREAIARAVNAGPDDVVLFVGSGATSAVNKLVGLLGLRISEPLE
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RAYGLSRHVPPDERPVVLVSPYEHHSNQLPWLESVAEVVEVDLDGDGQVDLADLDRKAAR
HHCCCCCCCCCCCCCEEEECCCHHCCCCCCHHHHHHHHHEECCCCCCCEEHHHHHHHHHH
YAGRPLRVGAFSAGSNVTGALTDVRAVARVLHRRGFLACADYAAAGPYVPIDMHPADADE
HCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEEEEECCCCCCHH
RLDAIVVSTHKFAGGPEGSGILVAHRALFRSRTPERPGGGTVEYVAAFDRLSVDYTERLA
HHCEEEEECHHCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
EREEGGTPDILGDVRAGLAFLVKEALGPEAILAHETALAERAMARLRRHPRIRLYGPAHG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
PRLPILSFNVEGLHHDFVSALLDHLFGIQNRAGCSCAGPYGHRLLGIGPERSSELRRAIA
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHH
LGVLALKPGWVRISLPYTATEDEIEFLLEAVELVADHGEAFLPLYRLGWGDGMWRPLDAA
HHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCC
PADPVAVELTVEAVRAALLREEPPAPPAEEPVTEAQAAALRRDYLDEARRLATELEARHA
CCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQPLRWNPPTGDAFVDRLVWFRYVHADPSAPAA
CCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]