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The map label for this gene is nadA [H]

Identifier: 220918583

GI number: 220918583

Start: 3903828

End: 3904832

Strand: Reverse

Name: nadA [H]

Synonym: A2cp1_3491

Alternate gene names: 220918583

Gene position: 3904832-3903828 (Counterclockwise)

Preceding gene: 220918584

Following gene: 220918580

Centisome position: 77.64

GC content: 70.05

Gene sequence:

>1005_bases
ATGACCCTGCCCGTCGTCCCCATCCACGACCCCGTCGCGCACCCCGTCAGCGGCAGCGACCTCCCCGCCGCCGAGGTGGC
CGGGCTCGAGGCGGAGATCCGCGCCCTGGCGAAGGAGAAGGACGCGGTCATCCTGGCGCACAACTACCAGGTGCCCGAGG
TGCAGAACGTGGCCGACCACGTCGGCGACTCGCTGCAGCTCGCCATCCTGGGCCAGAAGGTGCCGCAGTCCACCATCGTG
TTCTGCGGCGTGCACTTCATGGCCGAGTCGGCCAAGGTGCTGGCGCCCGACAAGCGCGTGCTCCTGCCGAACCTGTCCGC
GGGCTGCTCGCTGGCGGACTCGATCACCGCCGAGTCGCTGGAGGACTGGAAGGCGCGCTACCCGGGCCACGCGGTGGTGA
CCTACGTGAACTCCACCGCCGAGGTGAAGGCGCTCTCCGACATCTGCTGCACCAGCGCGAACGCCGCCTCGGTGGTGCGC
TCGCTGCCGCAGCAGAAGATCCTGTTCACGCCGGACCGGAACCTGGGCCGCTGGGTGGCGGCGAAGGTGCCGGAGAAGGA
GGTGGTGGTCTACGACGGCTGCTGCCCCGTGCACGACGTGCTGCGCTCGGCCAACGTGGAGAAGGTGCGCGCCAGCCGCC
CCGAGGCGGTGGTCATCGCGCACCCGGAGTGCCGTGCCGACGTGATCGACGTCGCCGACGTGGTCTGCTCCACCACCGCC
ATGATCTCCGCGGTGGAGAAGTTCCCGTCGGCCCGGACGTTCATCGTCGCCACCGAGCACGGCATCGTGCACCAGATGAA
GAAGCGCTGGCCGGATCGCGAGTTCATCGTGGCCGACGGCTGCATCGGCTGTCGCATGCACTGCCCCTACATGAAGATGA
TCGACCTGCTCATGATCCGCGACGCGCTGGTGCGCGGGAAGCACGAGGTGAGGGTCGAGCCGGACGTCGCCGCCGGCGCG
CGCCGCGCGCTGGAGCGGATGATCGCGGTGCCGCGGGACGCGTGA

Upstream 100 bases:

>100_bases
AGTCGGCCACCCTGGTCGGCCTCGTGCGCCGCGAGTTCTGGCGCCTATTTCCCGCCGGCACGGGCGACATCAAGCCCGCG
CGCGGCGCCCGGGTGAAGCC

Downstream 100 bases:

>100_bases
GCCGGCCAGGGCCGGCGCGGCGCCCTCCGGGGCCCGGCCGCCGGCCCGCCGCCTACCCGCCGATGGCGAAGTAGACCACG
AACGCGATCGAGGCCCCGAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTLPVVPIHDPVAHPVSGSDLPAAEVAGLEAEIRALAKEKDAVILAHNYQVPEVQNVADHVGDSLQLAILGQKVPQSTIV
FCGVHFMAESAKVLAPDKRVLLPNLSAGCSLADSITAESLEDWKARYPGHAVVTYVNSTAEVKALSDICCTSANAASVVR
SLPQQKILFTPDRNLGRWVAAKVPEKEVVVYDGCCPVHDVLRSANVEKVRASRPEAVVIAHPECRADVIDVADVVCSTTA
MISAVEKFPSARTFIVATEHGIVHQMKKRWPDREFIVADGCIGCRMHCPYMKMIDLLMIRDALVRGKHEVRVEPDVAAGA
RRALERMIAVPRDA

Sequences:

>Translated_334_residues
MTLPVVPIHDPVAHPVSGSDLPAAEVAGLEAEIRALAKEKDAVILAHNYQVPEVQNVADHVGDSLQLAILGQKVPQSTIV
FCGVHFMAESAKVLAPDKRVLLPNLSAGCSLADSITAESLEDWKARYPGHAVVTYVNSTAEVKALSDICCTSANAASVVR
SLPQQKILFTPDRNLGRWVAAKVPEKEVVVYDGCCPVHDVLRSANVEKVRASRPEAVVIAHPECRADVIDVADVVCSTTA
MISAVEKFPSARTFIVATEHGIVHQMKKRWPDREFIVADGCIGCRMHCPYMKMIDLLMIRDALVRGKHEVRVEPDVAAGA
RRALERMIAVPRDA
>Mature_333_residues
TLPVVPIHDPVAHPVSGSDLPAAEVAGLEAEIRALAKEKDAVILAHNYQVPEVQNVADHVGDSLQLAILGQKVPQSTIVF
CGVHFMAESAKVLAPDKRVLLPNLSAGCSLADSITAESLEDWKARYPGHAVVTYVNSTAEVKALSDICCTSANAASVVRS
LPQQKILFTPDRNLGRWVAAKVPEKEVVVYDGCCPVHDVLRSANVEKVRASRPEAVVIAHPECRADVIDVADVVCSTTAM
ISAVEKFPSARTFIVATEHGIVHQMKKRWPDREFIVADGCIGCRMHCPYMKMIDLLMIRDALVRGKHEVRVEPDVAAGAR
RALERMIAVPRDA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=328, Percent_Identity=36.280487804878, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36223; Mature: 36092

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPVVPIHDPVAHPVSGSDLPAAEVAGLEAEIRALAKEKDAVILAHNYQVPEVQNVADH
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
VGDSLQLAILGQKVPQSTIVFCGVHFMAESAKVLAPDKRVLLPNLSAGCSLADSITAESL
CCCCEEEEEECCCCCCCCEEEHHHHHHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHHH
EDWKARYPGHAVVTYVNSTAEVKALSDICCTSANAASVVRSLPQQKILFTPDRNLGRWVA
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCCCCEEE
AKVPEKEVVVYDGCCPVHDVLRSANVEKVRASRPEAVVIAHPECRADVIDVADVVCSTTA
ECCCCCEEEEEECCCCHHHHHHCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
MISAVEKFPSARTFIVATEHGIVHQMKKRWPDREFIVADGCIGCRMHCPYMKMIDLLMIR
HHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCEECCCHHHHHHHHHHH
DALVRGKHEVRVEPDVAAGARRALERMIAVPRDA
HHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLPVVPIHDPVAHPVSGSDLPAAEVAGLEAEIRALAKEKDAVILAHNYQVPEVQNVADH
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
VGDSLQLAILGQKVPQSTIVFCGVHFMAESAKVLAPDKRVLLPNLSAGCSLADSITAESL
CCCCEEEEEECCCCCCCCEEEHHHHHHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHHH
EDWKARYPGHAVVTYVNSTAEVKALSDICCTSANAASVVRSLPQQKILFTPDRNLGRWVA
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCCCCEEE
AKVPEKEVVVYDGCCPVHDVLRSANVEKVRASRPEAVVIAHPECRADVIDVADVVCSTTA
ECCCCCEEEEEECCCCHHHHHHCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
MISAVEKFPSARTFIVATEHGIVHQMKKRWPDREFIVADGCIGCRMHCPYMKMIDLLMIR
HHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCEECCCHHHHHHHHHHH
DALVRGKHEVRVEPDVAAGARRALERMIAVPRDA
HHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA