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The map label for this gene is ntrC [H]

Identifier: 220918571

GI number: 220918571

Start: 3885261

End: 3886925

Strand: Direct

Name: ntrC [H]

Synonym: A2cp1_3479

Alternate gene names: 220918571

Gene position: 3885261-3886925 (Clockwise)

Preceding gene: 220918570

Following gene: 220918575

Centisome position: 77.25

GC content: 77.06

Gene sequence:

>1665_bases
ATGCCCGAGCTTGCCTTCTTCCGCCACGGCGAGGAGCTGCTGCGCGTCACCCTGACCGATCGCACCGCGCTCGGCAGCGG
CCCCGAGTGCGACGTCTCGCTGCCCGATCCCGCGCTCGCCCGCGTGCAGGCGGTGGTGGAGCGGCGCGCCGACGGGTGGT
GGCTGGTGGACCGGTCCGGCGCGGGCACCGCGGTGGGCGGGGCGCCGGTGCGCGAGGCGCGGCTCGGCGACGGCGCCGAC
CTCGCGCTCGGCGCCTGGCGGGCGCTCTTCCGCGCGGCCGAGGGCGTCGCGCCGGGCGCGGGCGAGACGCGGCTGCGCGC
GCACGACGAGCCGCCGGCCGGGGCGCCGCCGCCCGCGCGGCTCCGGCTCCGCGCCGGCGGCCGCGAGCGCACCGTCCCGG
TCACCGCCGCGGGCGTGGTGGTGGGCAAGGACCCGACCTGCGACGCGCCGCTCGACGACGCGTTCGTCTCGGCCCGCCAC
CTGCGCGTCGAGGCGCGCGGCGGCCGGTGGGCGCTCGTGGACCTCGGCTCGACGAACGGCACGTTCATCAGCGGCGCGCG
GGTGACGCGCGCGGAGCTGCCGTTCGGCCTGCCGGTTCAGCTCGGGGACGCGGAGATCGTCCTCGAGCCGCGCGAGGCGC
CCGAGCCCGCCCGCGCCGAGGCGTTCGAGGGGATGATCTCGCGCGACGCCGCCATGCGGCAGGCGTTCGAGCTGGTGGAG
CGGGTCGGCCCGTCGGAGGCGGCGGTGACCATCCTCGGCGAGACCGGCACCGGCAAGGAGCTGTTCGCCCGCGCGCTGCA
CGCGCGCTCCGCGCGGCGGGACGGGCCGTTCATCCCGGTGAACTGCTCGGCCATCGCCGAGACGCTCATCGAGTCCGAGC
TGTTCGGCCACGAGAAGGGCGCGTTCTCCGGCGCGGAGCGCATGCGCAAGGGCGCCTTCGAGGAGGCCGACCGCGGCACG
CTGTTCCTGGACGAGATCGGCGAGCTCCCGCTCGACCTGCAGCCGAAGCTGCTCCGCGTGCTCGAGCTGGGCGAGGTGAA
GCGGGTGGGCGCGTCCAGGCCGATCCAGGTGAGCGTGCGCATCGTGGCCGCCACCCACCGCGACCTGCGCGCGCAGGTGC
GCGCCGGGCGGTTCCGCGAGGACCTGTTCTACCGGCTCTGCGTGGTGCCCATCACCGTCCCGCCGCTGCGCCGGCGCGCC
GGCGACGTGCGGGCGCTGGCGGAGACGTTCCTGGCGCGCGCGGCGCCGCGCGGCGTGGCGCTGCGCTGGAGCGAGGAGGC
GCTCGCGAAGCTCGAGGCGTACGACTGGCCCGGGAACGTCCGGCAGCTCCGGAACGTGGTGCAGCGCGCGCTCCTGTTCC
GGGGCGAGGGGCTGGCCATCGGGCCGGCGGCGGTCACCTTCGAGGACACGCGCGCCGCGCCCGCCGACGGCGGCGACGAC
GACACGCTGTACGTGCGCGGCCTCACGCTGGAGGAGATCGAGCGGGAGGCGATCCGCCTGTCCCTGCGACGCAACCGCGG
CAAGCGCGCCGCGGTGGTGAAGGAGCTGCGCATCGCCAAGAGCACCGTGATGAAGCGCATCGGCCAGTGGGGCCTGCACG
ACGAGGGTCGGCCGCCGGGCGAGGCGCCGGATCCCGAGCCCGACGACGAGGCCGAGGTGGCCTGA

Upstream 100 bases:

>100_bases
GCTCCGGCTGCCCGGGTCAGCCACGCACTCCCCGTATGGCCGCCCCCTCGGCGGAGGGCGGACCTTCACCCAGGGCGCGG
GGTTGGCTAGCCTCGGGCGC

Downstream 100 bases:

>100_bases
CGCGGGGGCGCAGCCCTCGTCGGCTAATGCATCCAGCCGTCGCCCCGACGCAGCAGCGTCAGCGGGCTCGTGTCCTCGGG
CAGGTCCACCGCGTCCGGGC

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MPELAFFRHGEELLRVTLTDRTALGSGPECDVSLPDPALARVQAVVERRADGWWLVDRSGAGTAVGGAPVREARLGDGAD
LALGAWRALFRAAEGVAPGAGETRLRAHDEPPAGAPPPARLRLRAGGRERTVPVTAAGVVVGKDPTCDAPLDDAFVSARH
LRVEARGGRWALVDLGSTNGTFISGARVTRAELPFGLPVQLGDAEIVLEPREAPEPARAEAFEGMISRDAAMRQAFELVE
RVGPSEAAVTILGETGTGKELFARALHARSARRDGPFIPVNCSAIAETLIESELFGHEKGAFSGAERMRKGAFEEADRGT
LFLDEIGELPLDLQPKLLRVLELGEVKRVGASRPIQVSVRIVAATHRDLRAQVRAGRFREDLFYRLCVVPITVPPLRRRA
GDVRALAETFLARAAPRGVALRWSEEALAKLEAYDWPGNVRQLRNVVQRALLFRGEGLAIGPAAVTFEDTRAAPADGGDD
DTLYVRGLTLEEIEREAIRLSLRRNRGKRAAVVKELRIAKSTVMKRIGQWGLHDEGRPPGEAPDPEPDDEAEVA

Sequences:

>Translated_554_residues
MPELAFFRHGEELLRVTLTDRTALGSGPECDVSLPDPALARVQAVVERRADGWWLVDRSGAGTAVGGAPVREARLGDGAD
LALGAWRALFRAAEGVAPGAGETRLRAHDEPPAGAPPPARLRLRAGGRERTVPVTAAGVVVGKDPTCDAPLDDAFVSARH
LRVEARGGRWALVDLGSTNGTFISGARVTRAELPFGLPVQLGDAEIVLEPREAPEPARAEAFEGMISRDAAMRQAFELVE
RVGPSEAAVTILGETGTGKELFARALHARSARRDGPFIPVNCSAIAETLIESELFGHEKGAFSGAERMRKGAFEEADRGT
LFLDEIGELPLDLQPKLLRVLELGEVKRVGASRPIQVSVRIVAATHRDLRAQVRAGRFREDLFYRLCVVPITVPPLRRRA
GDVRALAETFLARAAPRGVALRWSEEALAKLEAYDWPGNVRQLRNVVQRALLFRGEGLAIGPAAVTFEDTRAAPADGGDD
DTLYVRGLTLEEIEREAIRLSLRRNRGKRAAVVKELRIAKSTVMKRIGQWGLHDEGRPPGEAPDPEPDDEAEVA
>Mature_553_residues
PELAFFRHGEELLRVTLTDRTALGSGPECDVSLPDPALARVQAVVERRADGWWLVDRSGAGTAVGGAPVREARLGDGADL
ALGAWRALFRAAEGVAPGAGETRLRAHDEPPAGAPPPARLRLRAGGRERTVPVTAAGVVVGKDPTCDAPLDDAFVSARHL
RVEARGGRWALVDLGSTNGTFISGARVTRAELPFGLPVQLGDAEIVLEPREAPEPARAEAFEGMISRDAAMRQAFELVER
VGPSEAAVTILGETGTGKELFARALHARSARRDGPFIPVNCSAIAETLIESELFGHEKGAFSGAERMRKGAFEEADRGTL
FLDEIGELPLDLQPKLLRVLELGEVKRVGASRPIQVSVRIVAATHRDLRAQVRAGRFREDLFYRLCVVPITVPPLRRRAG
DVRALAETFLARAAPRGVALRWSEEALAKLEAYDWPGNVRQLRNVVQRALLFRGEGLAIGPAAVTFEDTRAAPADGGDDD
TLYVRGLTLEEIEREAIRLSLRRNRGKRAAVVKELRIAKSTVMKRIGQWGLHDEGRPPGEAPDPEPDDEAEVA

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=320, Percent_Identity=44.375, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788550, Length=318, Percent_Identity=42.4528301886792, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=44.7204968944099, Blast_Score=242, Evalue=6e-65,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=41.5384615384615, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1789087, Length=277, Percent_Identity=46.5703971119134, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=42.3780487804878, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87082152, Length=338, Percent_Identity=42.0118343195266, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=41.8181818181818, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=40.8360128617363, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788905, Length=231, Percent_Identity=47.1861471861472, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787583, Length=317, Percent_Identity=36.5930599369085, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=30.5295950155763, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789828, Length=245, Percent_Identity=36.3265306122449, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59889; Mature: 59758

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50006 FHA_DOMAIN ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELAFFRHGEELLRVTLTDRTALGSGPECDVSLPDPALARVQAVVERRADGWWLVDRSG
CCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
AGTAVGGAPVREARLGDGADLALGAWRALFRAAEGVAPGAGETRLRAHDEPPAGAPPPAR
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCE
LRLRAGGRERTVPVTAAGVVVGKDPTCDAPLDDAFVSARHLRVEARGGRWALVDLGSTNG
EEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHEEEEEEECCCEEEEEECCCCCC
TFISGARVTRAELPFGLPVQLGDAEIVLEPREAPEPARAEAFEGMISRDAAMRQAFELVE
CEEECCEEECCCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVGPSEAAVTILGETGTGKELFARALHARSARRDGPFIPVNCSAIAETLIESELFGHEKG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCC
AFSGAERMRKGAFEEADRGTLFLDEIGELPLDLQPKLLRVLELGEVKRVGASRPIQVSVR
CCHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
IVAATHRDLRAQVRAGRFREDLFYRLCVVPITVPPLRRRAGDVRALAETFLARAAPRGVA
EEEEHHHHHHHHHHHCHHHHHHHHHHHEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
LRWSEEALAKLEAYDWPGNVRQLRNVVQRALLFRGEGLAIGPAAVTFEDTRAAPADGGDD
EEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCCCCCC
DTLYVRGLTLEEIEREAIRLSLRRNRGKRAAVVKELRIAKSTVMKRIGQWGLHDEGRPPG
CEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EAPDPEPDDEAEVA
CCCCCCCCCCCCCC
>Mature Secondary Structure 
PELAFFRHGEELLRVTLTDRTALGSGPECDVSLPDPALARVQAVVERRADGWWLVDRSG
CCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
AGTAVGGAPVREARLGDGADLALGAWRALFRAAEGVAPGAGETRLRAHDEPPAGAPPPAR
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCE
LRLRAGGRERTVPVTAAGVVVGKDPTCDAPLDDAFVSARHLRVEARGGRWALVDLGSTNG
EEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHEEEEEEECCCEEEEEECCCCCC
TFISGARVTRAELPFGLPVQLGDAEIVLEPREAPEPARAEAFEGMISRDAAMRQAFELVE
CEEECCEEECCCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVGPSEAAVTILGETGTGKELFARALHARSARRDGPFIPVNCSAIAETLIESELFGHEKG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCC
AFSGAERMRKGAFEEADRGTLFLDEIGELPLDLQPKLLRVLELGEVKRVGASRPIQVSVR
CCHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
IVAATHRDLRAQVRAGRFREDLFYRLCVVPITVPPLRRRAGDVRALAETFLARAAPRGVA
EEEEHHHHHHHHHHHCHHHHHHHHHHHEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
LRWSEEALAKLEAYDWPGNVRQLRNVVQRALLFRGEGLAIGPAAVTFEDTRAAPADGGDD
EEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCCCCCC
DTLYVRGLTLEEIEREAIRLSLRRNRGKRAAVVKELRIAKSTVMKRIGQWGLHDEGRPPG
CEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EAPDPEPDDEAEVA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]