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The map label for this gene is thrB [H]

Identifier: 220918568

GI number: 220918568

Start: 3882657

End: 3883625

Strand: Reverse

Name: thrB [H]

Synonym: A2cp1_3476

Alternate gene names: 220918568

Gene position: 3883625-3882657 (Counterclockwise)

Preceding gene: 220918569

Following gene: 220918566

Centisome position: 77.22

GC content: 75.75

Gene sequence:

>969_bases
ATGGCCCTCTACACCGTCCTCTCCAGCGAGCAGATCGCCGCCGCGGTCCGGAGCTTCGGGCTCCCCGCGCCGGACCGCGT
CCAGCCGGAGCCGAAGGGCAGCGTCAACACGAACTACCACCTGTGGGCCGGCGGCGAGCGCTGGTTCCTGCGGCTCAACG
AGGGGAAGACCGACGCCGACGTGCGGTTCGAGGCCGAGGTCCAGCGCTACCTCCACGAGGCCCGGTTCCCGGTGGCGCGC
CTGCGCCTCGCGGCGGACGGGCGGCCCTGGGTGCCGGTGGACGGCAAGCAGGCGATGCTGTTCGCCTACGCGGCCGGCGA
GGAGATCTCGCGCGACGCCGCGGGCCCGGAGCGCTGCCGTCGCGTGGGCGAGCAGCTCGGGCGGCTGCACGAGCTCGCGT
CCGGCTTCGTGCCGGAGCGCCGCAACCCGTACGCGCCGGAGCGCGTGCGCGGGTGGATCTCGGAGCTGCGGCCGGACGGC
GGGGGCGACGCCGACGTGCGGGCGGCGCTGCCGATGCTGGAGGAGGAGCTGGCGCGCGCGGAGCGGCTCCCCGGCGCGCC
GCGCGGGCTGGTCCACGGCGACCTGTTCATCGACAACGTGCTCTGGATCGGCGATCGCGTCGGCGCGGTGCTCGACTGGG
AGATGAGCTGCGTGGACCCGTTCGCCTACGACCTCGGGGTCGCGGTGAACGCCTGGTGCTACGTGGATCGCTACGACCCG
GCGCGCGCCGCCGCGCTGCTCGCCGGCTACCGCGCGAAGCGCCGGCTCGAGCCGGAGACCGCGGACGCGCTCTACCCGTG
GGCGCGCTACGCCGCGCTGCGCTTCACCGCCTCGCGCATCCACGCGTTCCACCGCGCCGCGCTCGGCGCCGACCGGCTGG
CCTGGAAGGACTGGAGGCGCTACCGCGACCGGCTCGCCGCGCTGCGCGACATGGGCGAGGGCGGCTTCCGGGCGCTGCTC
GGCGTCTGA

Upstream 100 bases:

>100_bases
GCGGGGCCGCCGCCGGCGACGCTCCCGCCGGCCCCCGACCGTTGACGGGGACGACCCTGGAGGGCATGCTCCGCCTCCCG
GCTCCGGCCGGCCTCGACCG

Downstream 100 bases:

>100_bases
CCCGCTACAGCCCGGCGGTGAACAGCCAGCGCCCGTCCACCTTGCGCAGGTGCATGCGGTGCACGTCGGAGTCGCGCCGC
GGCACCACGCCGGTCGCGGT

Product: Homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MALYTVLSSEQIAAAVRSFGLPAPDRVQPEPKGSVNTNYHLWAGGERWFLRLNEGKTDADVRFEAEVQRYLHEARFPVAR
LRLAADGRPWVPVDGKQAMLFAYAAGEEISRDAAGPERCRRVGEQLGRLHELASGFVPERRNPYAPERVRGWISELRPDG
GGDADVRAALPMLEEELARAERLPGAPRGLVHGDLFIDNVLWIGDRVGAVLDWEMSCVDPFAYDLGVAVNAWCYVDRYDP
ARAAALLAGYRAKRRLEPETADALYPWARYAALRFTASRIHAFHRAALGADRLAWKDWRRYRDRLAALRDMGEGGFRALL
GV

Sequences:

>Translated_322_residues
MALYTVLSSEQIAAAVRSFGLPAPDRVQPEPKGSVNTNYHLWAGGERWFLRLNEGKTDADVRFEAEVQRYLHEARFPVAR
LRLAADGRPWVPVDGKQAMLFAYAAGEEISRDAAGPERCRRVGEQLGRLHELASGFVPERRNPYAPERVRGWISELRPDG
GGDADVRAALPMLEEELARAERLPGAPRGLVHGDLFIDNVLWIGDRVGAVLDWEMSCVDPFAYDLGVAVNAWCYVDRYDP
ARAAALLAGYRAKRRLEPETADALYPWARYAALRFTASRIHAFHRAALGADRLAWKDWRRYRDRLAALRDMGEGGFRALL
GV
>Mature_321_residues
ALYTVLSSEQIAAAVRSFGLPAPDRVQPEPKGSVNTNYHLWAGGERWFLRLNEGKTDADVRFEAEVQRYLHEARFPVARL
RLAADGRPWVPVDGKQAMLFAYAAGEEISRDAAGPERCRRVGEQLGRLHELASGFVPERRNPYAPERVRGWISELRPDGG
GDADVRAALPMLEEELARAERLPGAPRGLVHGDLFIDNVLWIGDRVGAVLDWEMSCVDPFAYDLGVAVNAWCYVDRYDPA
RAAALLAGYRAKRRLEPETADALYPWARYAALRFTASRIHAFHRAALGADRLAWKDWRRYRDRLAALRDMGEGGFRALLG
V

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 36110; Mature: 35979

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALYTVLSSEQIAAAVRSFGLPAPDRVQPEPKGSVNTNYHLWAGGERWFLRLNEGKTDAD
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCC
VRFEAEVQRYLHEARFPVARLRLAADGRPWVPVDGKQAMLFAYAAGEEISRDAAGPERCR
EEEHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHH
RVGEQLGRLHELASGFVPERRNPYAPERVRGWISELRPDGGGDADVRAALPMLEEELARA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ERLPGAPRGLVHGDLFIDNVLWIGDRVGAVLDWEMSCVDPFAYDLGVAVNAWCYVDRYDP
HHCCCCCCCCEECHHHHHHHHHHCCCCCEEEECCHHHCCHHHHHHCCCEEEEEEEECCCH
ARAAALLAGYRAKRRLEPETADALYPWARYAALRFTASRIHAFHRAALGADRLAWKDWRR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YRDRLAALRDMGEGGFRALLGV
HHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
ALYTVLSSEQIAAAVRSFGLPAPDRVQPEPKGSVNTNYHLWAGGERWFLRLNEGKTDAD
EEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCC
VRFEAEVQRYLHEARFPVARLRLAADGRPWVPVDGKQAMLFAYAAGEEISRDAAGPERCR
EEEHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHH
RVGEQLGRLHELASGFVPERRNPYAPERVRGWISELRPDGGGDADVRAALPMLEEELARA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ERLPGAPRGLVHGDLFIDNVLWIGDRVGAVLDWEMSCVDPFAYDLGVAVNAWCYVDRYDP
HHCCCCCCCCEECHHHHHHHHHHCCCCCEEEECCHHHCCHHHHHHCCCEEEEEEEECCCH
ARAAALLAGYRAKRRLEPETADALYPWARYAALRFTASRIHAFHRAALGADRLAWKDWRR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YRDRLAALRDMGEGGFRALLGV
HHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA