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The map label for this gene is des6 [H]

Identifier: 220918475

GI number: 220918475

Start: 3771839

End: 3772927

Strand: Direct

Name: des6 [H]

Synonym: A2cp1_3380

Alternate gene names: 220918475

Gene position: 3771839-3772927 (Clockwise)

Preceding gene: 220918474

Following gene: 220918477

Centisome position: 75.0

GC content: 73.92

Gene sequence:

>1089_bases
ATGACGGCATCGGCCCTCCGCGCCCGCTTCCCACGCGACGACGGGTTCCACGCGGACCTGAAGCGCCGCGTCGCGGCGTA
CTTCGCGGCGACGGGCGAGCCGGCGCAGGGGGGCCGCGCGATGCACGTGAAGACGGCCGCCATCTTCGGCTGGTTCGGCG
CCTCGTATGCGCTGCTCCTCGCCTGGGGGGACGTCTCGGCGTGGCTCGCGATCGGCCTCACCGTCTCGATCGCGCTGGCG
ACCGCCGGGATCGGCTTCTCGGTCATGCACGACGCCAACCACGGCGCCTACTCGCGGTCGCCCCGCGTGAACCGCGCCGT
CGGGCTCGCGCTCGACTTCATCGGCGCGAGCTCGTACGTCTGGCGCTTCAAGCACAACGTGCAGCACCACACCTACACCA
ACGTCGCCGGCCTGGACGCCGACATCGACGCCGAGCCGTTCCTCCGGCTCGCCGGCGCACAGCGCCGCCGCGCCCTCCAC
CGCTTCCAGGGCGCGTACGCCTGGCCGCTGTACGGCGTGCTCTCGCTGAAGTGGTGGCTGGTGGACGACGTCGTGGACCT
CGTCCGCGGGACGATCGGCGGCCATCCGTACCCGCGGCCGCGCGGGCGCGAGCTCGCCGCCGTGGTCGCCGGCAAGGCCA
CGTTCCTCGGCTGGGCGCTTGTCGTCCCGGTCCTCGTCCACGGGAGCGCGTGGCCCGTGGCCTTCTTCGTGCTCGGTTCG
CTCGTGCTCGGGGTGGTCATGGCGGTGGTCTTCCAGCTCGCGCACGCGGTCTCCGGCGCGCAGTTCCACGACGCGCCCGC
CGCAGACGGCCGCATGCCCGCGGCCTGGGCCGAGCACCAGGTCCGGACGACCGTGGACTTCGCGCGCTCGAGCCGGGTCC
TCGCCTGGTACCTGGGCGGCCTCAACTTCCAGATCGAGCACCACCTCTTCCCCGGCGTCTGCCACGTCCGCTACCCGGCG
CTCGCGACGATCGTGGAGGAGACGTGCCGCGCGCACGGGATCCCCTACCGCGCGGAGCCGTCGCTCGGGGCGGCCATCGC
CGCGCACCACCGGCACCTGCGCGCCCTGGGCGCGCCGGTGCCGGCGTGA

Upstream 100 bases:

>100_bases
ACGAGGTCCTGGTGGTGATGGGGGCGGCCGGCCAGCGCGGCGAGCTGACGGGGCCGACCGCGGTGACACCCGCGTGACAT
CCCCTGTCCATGTATTGCCC

Downstream 100 bases:

>100_bases
GGGACCGCCCGGACCGCCGGGCGACTTACCTGGTCGTCCCGGGCGGCGGCGACGTCGGCGCGGGCGGGGACGCCCCTTCG
CTCGAGCTCCCCGTCCCGGT

Product: Linoleoyl-CoA desaturase

Products: NA

Alternate protein names: Delta(6)-desaturase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTASALRARFPRDDGFHADLKRRVAAYFAATGEPAQGGRAMHVKTAAIFGWFGASYALLLAWGDVSAWLAIGLTVSIALA
TAGIGFSVMHDANHGAYSRSPRVNRAVGLALDFIGASSYVWRFKHNVQHHTYTNVAGLDADIDAEPFLRLAGAQRRRALH
RFQGAYAWPLYGVLSLKWWLVDDVVDLVRGTIGGHPYPRPRGRELAAVVAGKATFLGWALVVPVLVHGSAWPVAFFVLGS
LVLGVVMAVVFQLAHAVSGAQFHDAPAADGRMPAAWAEHQVRTTVDFARSSRVLAWYLGGLNFQIEHHLFPGVCHVRYPA
LATIVEETCRAHGIPYRAEPSLGAAIAAHHRHLRALGAPVPA

Sequences:

>Translated_362_residues
MTASALRARFPRDDGFHADLKRRVAAYFAATGEPAQGGRAMHVKTAAIFGWFGASYALLLAWGDVSAWLAIGLTVSIALA
TAGIGFSVMHDANHGAYSRSPRVNRAVGLALDFIGASSYVWRFKHNVQHHTYTNVAGLDADIDAEPFLRLAGAQRRRALH
RFQGAYAWPLYGVLSLKWWLVDDVVDLVRGTIGGHPYPRPRGRELAAVVAGKATFLGWALVVPVLVHGSAWPVAFFVLGS
LVLGVVMAVVFQLAHAVSGAQFHDAPAADGRMPAAWAEHQVRTTVDFARSSRVLAWYLGGLNFQIEHHLFPGVCHVRYPA
LATIVEETCRAHGIPYRAEPSLGAAIAAHHRHLRALGAPVPA
>Mature_361_residues
TASALRARFPRDDGFHADLKRRVAAYFAATGEPAQGGRAMHVKTAAIFGWFGASYALLLAWGDVSAWLAIGLTVSIALAT
AGIGFSVMHDANHGAYSRSPRVNRAVGLALDFIGASSYVWRFKHNVQHHTYTNVAGLDADIDAEPFLRLAGAQRRRALHR
FQGAYAWPLYGVLSLKWWLVDDVVDLVRGTIGGHPYPRPRGRELAAVVAGKATFLGWALVVPVLVHGSAWPVAFFVLGSL
VLGVVMAVVFQLAHAVSGAQFHDAPAADGRMPAAWAEHQVRTTVDFARSSRVLAWYLGGLNFQIEHHLFPGVCHVRYPAL
ATIVEETCRAHGIPYRAEPSLGAAIAAHHRHLRALGAPVPA

Specific function: Unknown

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17542820, Length=303, Percent_Identity=28.0528052805281, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542396, Length=276, Percent_Identity=26.8115942028986, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: =1.14.19.3 [H]

Molecular weight: Translated: 39132; Mature: 39001

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASALRARFPRDDGFHADLKRRVAAYFAATGEPAQGGRAMHVKTAAIFGWFGASYALLL
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHEEEEE
AWGDVSAWLAIGLTVSIALATAGIGFSVMHDANHGAYSRSPRVNRAVGLALDFIGASSYV
EECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHE
WRFKHNVQHHTYTNVAGLDADIDAEPFLRLAGAQRRRALHRFQGAYAWPLYGVLSLKWWL
EEEHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VDDVVDLVRGTIGGHPYPRPRGRELAAVVAGKATFLGWALVVPVLVHGSAWPVAFFVLGS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVLGVVMAVVFQLAHAVSGAQFHDAPAADGRMPAAWAEHQVRTTVDFARSSRVLAWYLGG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
LNFQIEHHLFPGVCHVRYPALATIVEETCRAHGIPYRAEPSLGAAIAAHHRHLRALGAPV
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PA
CC
>Mature Secondary Structure 
TASALRARFPRDDGFHADLKRRVAAYFAATGEPAQGGRAMHVKTAAIFGWFGASYALLL
CCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHEEEEE
AWGDVSAWLAIGLTVSIALATAGIGFSVMHDANHGAYSRSPRVNRAVGLALDFIGASSYV
EECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHE
WRFKHNVQHHTYTNVAGLDADIDAEPFLRLAGAQRRRALHRFQGAYAWPLYGVLSLKWWL
EEEHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VDDVVDLVRGTIGGHPYPRPRGRELAAVVAGKATFLGWALVVPVLVHGSAWPVAFFVLGS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVLGVVMAVVFQLAHAVSGAQFHDAPAADGRMPAAWAEHQVRTTVDFARSSRVLAWYLGG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
LNFQIEHHLFPGVCHVRYPALATIVEETCRAHGIPYRAEPSLGAAIAAHHRHLRALGAPV
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8389613; 8905231 [H]