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The map label for this gene is ycaN [C]

Identifier: 220918458

GI number: 220918458

Start: 3741823

End: 3742740

Strand: Direct

Name: ycaN [C]

Synonym: A2cp1_3362

Alternate gene names: 220918458

Gene position: 3741823-3742740 (Clockwise)

Preceding gene: 220918454

Following gene: 220918459

Centisome position: 74.4

GC content: 72.88

Gene sequence:

>918_bases
ATGGCCTTCACACCGCTCAACGCGCTCAACGCGTTCATCGCGGTCGCCCGTCGCCGCAGCTTCGCCGCGGCCGCGCGGCA
CCTCGGCGTCTCCACGTCGGCCCTCAGCCAGTCCGTCCGGCAGCTCGAGACACGCCTCGGCGTCACGCTCCTCACGCGGA
CGTCGCGCACCGTGGCCCTCACCGACGCGGGGCAGCGCCTGCTCGAGAACGCGGGGGCGGCGGTGGACCAGGCGCTGGAA
TCGCTGAAGACCGTGTCCGTCCGGCCCGGCGAGGTCACCGGCCGCGTGCGGCTCACCGTGCCCAGCACCGCGGTCACGCC
CGTGCTCGCCCGGCTCCTGCCGCGGTTCATCGAGCGACACCCCAGGGTGGAGGTCGAGGTGCAGGTGGAGAGCCGGTTCG
TGAACATCATCGCCGAAGGGCTCGACGCCGGCATCCGGCTGAGCGAATCCATCGAGCGCGACATGGTCCAGGTGCGGCTC
ACCGAGCCCGGCCGCTTCGTCGTGGTCGGCGCGCCCTCCTACCTCGCGCGGCGCGGCACGCCGGAGAAGCCACAGGATCT
CCTGCAGCACGACTGCATCTGCATCCGCTCCAGCGTGCACGGGGCGAGGTACGCCTGGGAGCTCGAGCGCGGAAAGAAGT
CCTGGCGCGTCCCGGTCCAGGGGACGGTGACCACGAACGATCCGGTGCTGATGCACGCCCTGGCCGTCGCCGGCGTGGGC
CTGCTCTACTCGTTCGAGCCCGAGGTCGCTGACGACCTGCGCAGCGGGCGGCTCCGGCTCGTGCTCGAGCCCTACGCCGC
GGCGGTGCCGGGCTTCTTCCTCTACTTCCCCAGCCGCGCGCAGGTGTCCCCGGCGCTCCGGGCCTTCGTGGACGTCGCCC
GCGAGGTGGCGGGGCAGTCGAGGACGCGGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCATGCGCGTTCCGGGGCACCGACGCTCCCCCGTCGGCCGAAAGAGGATCGTAGGATCCCGGCGGCCGCACCGGCGCCGG
CAAGGAGGAGGACGCGCACC

Downstream 100 bases:

>100_bases
TCCGCGCCGGCGCTCGCCGCGGCGTTCGCGCGTTCCGCGCGACCGCCACGTGAAGGCTTCCTTCACGCCTCATGCGCGTT
CCTCCCGTTTCGCCGCGACT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAFTPLNALNAFIAVARRRSFAAAARHLGVSTSALSQSVRQLETRLGVTLLTRTSRTVALTDAGQRLLENAGAAVDQALE
SLKTVSVRPGEVTGRVRLTVPSTAVTPVLARLLPRFIERHPRVEVEVQVESRFVNIIAEGLDAGIRLSESIERDMVQVRL
TEPGRFVVVGAPSYLARRGTPEKPQDLLQHDCICIRSSVHGARYAWELERGKKSWRVPVQGTVTTNDPVLMHALAVAGVG
LLYSFEPEVADDLRSGRLRLVLEPYAAAVPGFFLYFPSRAQVSPALRAFVDVAREVAGQSRTRAG

Sequences:

>Translated_305_residues
MAFTPLNALNAFIAVARRRSFAAAARHLGVSTSALSQSVRQLETRLGVTLLTRTSRTVALTDAGQRLLENAGAAVDQALE
SLKTVSVRPGEVTGRVRLTVPSTAVTPVLARLLPRFIERHPRVEVEVQVESRFVNIIAEGLDAGIRLSESIERDMVQVRL
TEPGRFVVVGAPSYLARRGTPEKPQDLLQHDCICIRSSVHGARYAWELERGKKSWRVPVQGTVTTNDPVLMHALAVAGVG
LLYSFEPEVADDLRSGRLRLVLEPYAAAVPGFFLYFPSRAQVSPALRAFVDVAREVAGQSRTRAG
>Mature_304_residues
AFTPLNALNAFIAVARRRSFAAAARHLGVSTSALSQSVRQLETRLGVTLLTRTSRTVALTDAGQRLLENAGAAVDQALES
LKTVSVRPGEVTGRVRLTVPSTAVTPVLARLLPRFIERHPRVEVEVQVESRFVNIIAEGLDAGIRLSESIERDMVQVRLT
EPGRFVVVGAPSYLARRGTPEKPQDLLQHDCICIRSSVHGARYAWELERGKKSWRVPVQGTVTTNDPVLMHALAVAGVGL
LYSFEPEVADDLRSGRLRLVLEPYAAAVPGFFLYFPSRAQVSPALRAFVDVAREVAGQSRTRAG

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=34.5890410958904, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787589, Length=286, Percent_Identity=33.5664335664336, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=29.6928327645051, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789440, Length=272, Percent_Identity=27.9411764705882, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789639, Length=314, Percent_Identity=29.2993630573248, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=28.1456953642384, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=28.3737024221453, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=30.7142857142857, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788706, Length=215, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788887, Length=303, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=27.3648648648649, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693105, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=38.135593220339, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789173, Length=302, Percent_Identity=25.8278145695364, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=33.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786508, Length=129, Percent_Identity=32.5581395348837, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=122, Percent_Identity=33.6065573770492, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367136, Length=182, Percent_Identity=31.3186813186813, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33267; Mature: 33136

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: PS50931 HTH_LYSR ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTPLNALNAFIAVARRRSFAAAARHLGVSTSALSQSVRQLETRLGVTLLTRTSRTVAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEE
TDAGQRLLENAGAAVDQALESLKTVSVRPGEVTGRVRLTVPSTAVTPVLARLLPRFIERH
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEECEEEEEECCHHHHHHHHHHHHHHHHHC
PRVEVEVQVESRFVNIIAEGLDAGIRLSESIERDMVQVRLTEPGRFVVVGAPSYLARRGT
CCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHCEEEEEECCCCCEEEEECCHHHHHCCC
PEKPQDLLQHDCICIRSSVHGARYAWELERGKKSWRVPVQGTVTTNDPVLMHALAVAGVG
CCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
LLYSFEPEVADDLRSGRLRLVLEPYAAAVPGFFLYFPSRAQVSPALRAFVDVAREVAGQS
HEEECCCHHHHHHHCCCEEEEECCHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC
RTRAG
CCCCC
>Mature Secondary Structure 
AFTPLNALNAFIAVARRRSFAAAARHLGVSTSALSQSVRQLETRLGVTLLTRTSRTVAL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEE
TDAGQRLLENAGAAVDQALESLKTVSVRPGEVTGRVRLTVPSTAVTPVLARLLPRFIERH
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEECEEEEEECCHHHHHHHHHHHHHHHHHC
PRVEVEVQVESRFVNIIAEGLDAGIRLSESIERDMVQVRLTEPGRFVVVGAPSYLARRGT
CCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHCEEEEEECCCCCEEEEECCHHHHHCCC
PEKPQDLLQHDCICIRSSVHGARYAWELERGKKSWRVPVQGTVTTNDPVLMHALAVAGVG
CCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
LLYSFEPEVADDLRSGRLRLVLEPYAAAVPGFFLYFPSRAQVSPALRAFVDVAREVAGQS
HEEECCCHHHHHHHCCCEEEEECCHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC
RTRAG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]