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The map label for this gene is nhaA [H]

Identifier: 220918408

GI number: 220918408

Start: 3690330

End: 3691319

Strand: Reverse

Name: nhaA [H]

Synonym: A2cp1_3312

Alternate gene names: 220918408

Gene position: 3691319-3690330 (Counterclockwise)

Preceding gene: 220918415

Following gene: 220918407

Centisome position: 73.4

GC content: 78.48

Gene sequence:

>990_bases
ATGAGCGCGTCCGCTCCCCTCCCGGTCCGGCTCGATCCTCCGGTGGACCCGGCGCGGGATCACGTGCTCGGCGAGGCCGG
CGCGGAGCTGACGCTGGTCGAGTACGGCAGCTCCGCTTGCCCGCACTGCCACGCCGCCCACGCGGTCGTCGCAGACCTGC
GCGACCGGCTCCGGTACGTGTTCCGCCAGCGCCCATCCGCGCCAAGGCGGCCCGGCCGGCGGCCGAGCTGGCCGAGGCGG
CCGGGCTCGCCGGTGACGGCTTCTGGCGGGCGCCCTCCACCGCGCCTGCTGCTGCTGGCCGCCACCGCGCTCGCGGTCGC
CATCGCGAGCTCGCCGGCCCGCGCCGCGTTCACCGCCGCCTGGCAGGCGCCGCTCGGGCTGTCGCTGGGCGGCCACGCGT
TCGCGCTGCCGCTGGTGCAATGGGTGAACGACCTGGTCGCGATCGCGGTGGTGGCGCTGTTCGACTCCGGCGCGATCTCG
GTGCCGTGGCTGCTCGCGGCGGCGGCGGTGACCGCGCCCCTCGCCGGGCTGAGCCGGGCGGCGATCTCGGCGGCGCCGCC
GTACGCCGCGCTGGGCGTGCTGCTGTGGGCCTGCCTCCACGCGGCCGGGCTGCACCCCAGGCTGGCGGGGGTGATCCTGG
CGGTGGTGACGCCGACCCGGCCGCCGCCCGACCTCCGCGCGCTCACCGGGCAGGCGCAGGCGGTGCTGGAGGCGGAGCTG
CGCCGGGCGCGCGAGGGCGTGCTGCGCCACCGCTCGCTGCCGGCGCTGCGCGCGCTGGACGCCATCCACGATCGCATCGA
GTCCCCGCGGCGAAGATCGCGATCTTCGCCGCGTCGATGCTCGCCGGCGTCCTCGGCGCGCTGGTGCTCTGGCCCGGCGC
TCGCCCGCGGCGGAGGCGGAGGCACTCCCGGCGCCCGAGGGCTCCGAGGTGGACGCGGCGGGCACGTAGCCCGCCAGGGC
CGTTCCGGCGCCTGCGGCGGACGGGTATGA

Upstream 100 bases:

>100_bases
GCCCGAGCGCCCGGCCCGGGCTGGTGCTTGCCGCCCGCACGGCCCGGAGTCGAATCGCGCCGATGGCCGACCCGCTCGCC
TCGCGCCGGAAGGCCACCCG

Downstream 100 bases:

>100_bases
GTGCCGCCCATGTTCGAGCGCGATCCATCCCGCGCCGCGCCGGCCGGGGGCATCGCCCCGCCGGCCGGCCCCGGTGCCTA
CGCCGTCGTCTTCACCTCCC

Product: Na+/H+ antiporter NhaA

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSASAPLPVRLDPPVDPARDHVLGEAGAELTLVEYGSSACPHCHAAHAVVADLRDRLRYVFRQRPSAPRRPGRRPSWPRR
PGSPVTASGGRPPPRLLLLAATALAVAIASSPARAAFTAAWQAPLGLSLGGHAFALPLVQWVNDLVAIAVVALFDSGAIS
VPWLLAAAAVTAPLAGLSRAAISAAPPYAALGVLLWACLHAAGLHPRLAGVILAVVTPTRPPPDLRALTGQAQAVLEAEL
RRAREGVLRHRSLPALRALDAIHDRIESPRRRSRSSPRRCSPASSARWCSGPALARGGGGGTPGARGLRGGRGGHVARQG
RSGACGGRV

Sequences:

>Translated_329_residues
MSASAPLPVRLDPPVDPARDHVLGEAGAELTLVEYGSSACPHCHAAHAVVADLRDRLRYVFRQRPSAPRRPGRRPSWPRR
PGSPVTASGGRPPPRLLLLAATALAVAIASSPARAAFTAAWQAPLGLSLGGHAFALPLVQWVNDLVAIAVVALFDSGAIS
VPWLLAAAAVTAPLAGLSRAAISAAPPYAALGVLLWACLHAAGLHPRLAGVILAVVTPTRPPPDLRALTGQAQAVLEAEL
RRAREGVLRHRSLPALRALDAIHDRIESPRRRSRSSPRRCSPASSARWCSGPALARGGGGGTPGARGLRGGRGGHVARQG
RSGACGGRV
>Mature_328_residues
SASAPLPVRLDPPVDPARDHVLGEAGAELTLVEYGSSACPHCHAAHAVVADLRDRLRYVFRQRPSAPRRPGRRPSWPRRP
GSPVTASGGRPPPRLLLLAATALAVAIASSPARAAFTAAWQAPLGLSLGGHAFALPLVQWVNDLVAIAVVALFDSGAISV
PWLLAAAAVTAPLAGLSRAAISAAPPYAALGVLLWACLHAAGLHPRLAGVILAVVTPTRPPPDLRALTGQAQAVLEAELR
RAREGVLRHRSLPALRALDAIHDRIESPRRRSRSSPRRCSPASSARWCSGPALARGGGGGTPGARGLRGGRGGHVARQGR
SGACGGRV

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3004

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 34053; Mature: 33921

Theoretical pI: Translated: 12.22; Mature: 12.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASAPLPVRLDPPVDPARDHVLGEAGAELTLVEYGSSACPHCHAAHAVVADLRDRLRYV
CCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
FRQRPSAPRRPGRRPSWPRRPGSPVTASGGRPPPRLLLLAATALAVAIASSPARAAFTAA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
WQAPLGLSLGGHAFALPLVQWVNDLVAIAVVALFDSGAISVPWLLAAAAVTAPLAGLSRA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AISAAPPYAALGVLLWACLHAAGLHPRLAGVILAVVTPTRPPPDLRALTGQAQAVLEAEL
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RRAREGVLRHRSLPALRALDAIHDRIESPRRRSRSSPRRCSPASSARWCSGPALARGGGG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTPGARGLRGGRGGHVARQGRSGACGGRV
CCCCCCCCCCCCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure 
SASAPLPVRLDPPVDPARDHVLGEAGAELTLVEYGSSACPHCHAAHAVVADLRDRLRYV
CCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
FRQRPSAPRRPGRRPSWPRRPGSPVTASGGRPPPRLLLLAATALAVAIASSPARAAFTAA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
WQAPLGLSLGGHAFALPLVQWVNDLVAIAVVALFDSGAISVPWLLAAAAVTAPLAGLSRA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AISAAPPYAALGVLLWACLHAAGLHPRLAGVILAVVTPTRPPPDLRALTGQAQAVLEAEL
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RRAREGVLRHRSLPALRALDAIHDRIESPRRRSRSSPRRCSPASSARWCSGPALARGGGG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTPGARGLRGGRGGHVARQGRSGACGGRV
CCCCCCCCCCCCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA