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The map label for this gene is pgi [H]

Identifier: 220918368

GI number: 220918368

Start: 3639995

End: 3641635

Strand: Reverse

Name: pgi [H]

Synonym: A2cp1_3272

Alternate gene names: 220918368

Gene position: 3641635-3639995 (Counterclockwise)

Preceding gene: 220918369

Following gene: 220918367

Centisome position: 72.41

GC content: 72.58

Gene sequence:

>1641_bases
ATGCCCGATCGGACCGGACCCCTCCTCCGAACGCCTGCCTGGAGGGCGCTCGAGGCGCACCTCGCCGAGCTCCAGCCGCT
GCACCTGCGCGAGCTGTTCGCGCGCGATCCCGGCCGCGGCGAGCGGCTCGTCGCGGACGGCGCCGGGCTCCACCTCGACT
ACTCGAAGCAGCGCGTGACCGAGGAGACCGTCCGGTTGCTGGTCGCGCTCGCCGAGGCGCGCGGCCTGCCCGAGCGGCGC
GCGGCCATGTTCCGCGGCGAGAAGGTGAACGTCACCGAGGGCAGGGCGGTGCTGCACGTCGCGCTGCGCGCCCCGCGCGG
CGAGCGGATCCTGGTGGACGGGAACGACGTGGTGCCCGAGGTCCACGCCGTGCTGGACCGCATGGCGGCGTTCGCGGACC
AGGTGCGGAGCGGCGCCTGGACCGGGTTCACCGGCAAGCGCATCCGCACCGTGGTGAACGTCGGCATCGGCGGCTCGGAT
CTCGGCCCCGCCATGGCGTACCGGGCGCTGCGCGCGTACGCGATCCGGGACCTCGCGTTCCGCTTCGTCTCCAACGTGGA
CGGGACCGACCTCGCCGAGGCGGTCCGCGACCTCGATCCCGCCGAGACGCTGTTCCTGGTGGCGTCGAAGACGTTCACCA
CCCTCGAGACCATGACCAACGCCGCCTCGGCCCGGTCCTGGCTGCTCGCGGCGCTCGGCGATCCGCGCGCGGTGGCGCGC
CACTTCGTCGCCATCTCCACGAACGAGGCCGAGGTGCGCCGCTTCGGCATCGATCCCGCCAACATGTTCGGGTTCTGGGA
CTGGGTCGGCGGGCGCTACTCGATGGACTCGGCGATCGGGCTCTCGACCATGATCGCCGTCGGCCCCGAGGGCTTCCGCG
AGCTGCTCGCCGGCTTCCGCGAGATGGACGAGCACTTCCGGGACGCGCCGCTCGAGCGGAACCTGCCCGCGCTGATCGGC
CTGATCGGCGTGTGGAACGCGAACCTGCTCGGCGCGGGGACCGTCGCGGTCCTTCCCTACGATCAGTACCTCGACCGCTT
CCCCGCGTACCTGCAGCAGCTCACCATGGAGTCGAACGGGAAGCGCGTGACGGCCTCCGGCACGCCGGTGGAGGGTCACG
GCACGGGCGCGATCTACTGGGGCGAGCCGGGCACCAACGGCCAGCACTCGTTCTACCAGCTGCTCCACCAGGGCACGCAC
CTCGTCGCCTGCGACTTCATCGGCTTCTGCCAGCCGCTCCACGCGCTCGGCCGGCACCACGACCTGCTCATGGCCAACCT
GTTCGCGCAGGGCGAGGCGCTCGCGTTCGGGAAGACCGCGGAGGAGGCGCGCGCGGAGGGGACGCCGGAGCCGCTCGTGC
CGCACCGCACCTTCCCCGGGAACCGGCCCTCCAGCACCATCCTCTCGGACCGCCTCACCCCGCGCACGCTCGGCGCGCTC
GTCGCGCTCTACGAGCACGCCGTGTTCACCCAGGGCGTGATCTGGGACGTGGACTCGTTCGACCAGTGGGGCGTCGAGCT
GGGGAAGGTCCTCGCGAACCGGATCGTGAAGGAGCTGGAGTCGCCCGCGGAGCCGGCGCTGGCGCACGACGGCTCCACGA
ACGCGCTCATCCGGCGGTACCGCGCGAGGCGGGGCGGGTAG

Upstream 100 bases:

>100_bases
CGCGGTGACGCACCGTGAAAGCAGGCCCCCCGCCGCCCGCCCGGAGCGAGCCCCTCCGCCGCGCGTGCCAGGCGCGGTCG
AACGCGGTAAGAGCCTGCGC

Downstream 100 bases:

>100_bases
CGGGCCCGCGCTCCCCCGGGTATCGTGCGGCGGTTTGCGCGCGCTGCTCGAGATCCTGTACGTCGTCCTGCCGTTCGCCT
GCGTCGCGGCGGTCCCGGCG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MPDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVTEETVRLLVALAEARGLPERR
AAMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPEVHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSD
LGPAMAYRALRAYAIRDLAFRFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVAR
HFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFREMDEHFRDAPLERNLPALIG
LIGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNGKRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTH
LVACDFIGFCQPLHALGRHHDLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGAL
VALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRYRARRGG

Sequences:

>Translated_546_residues
MPDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVTEETVRLLVALAEARGLPERR
AAMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPEVHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSD
LGPAMAYRALRAYAIRDLAFRFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVAR
HFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFREMDEHFRDAPLERNLPALIG
LIGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNGKRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTH
LVACDFIGFCQPLHALGRHHDLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGAL
VALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRYRARRGG
>Mature_545_residues
PDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVTEETVRLLVALAEARGLPERRA
AMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPEVHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSDL
GPAMAYRALRAYAIRDLAFRFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVARH
FVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFREMDEHFRDAPLERNLPALIGL
IGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNGKRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTHL
VACDFIGFCQPLHALGRHHDLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGALV
ALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRYRARRGG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=552, Percent_Identity=53.6231884057971, Blast_Score=587, Evalue=1e-167,
Organism=Homo sapiens, GI296080693, Length=552, Percent_Identity=50.1811594202899, Blast_Score=530, Evalue=1e-150,
Organism=Escherichia coli, GI1790457, Length=545, Percent_Identity=55.4128440366973, Blast_Score=591, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71996708, Length=538, Percent_Identity=53.1598513011152, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71996703, Length=538, Percent_Identity=53.1598513011152, Blast_Score=550, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6319673, Length=540, Percent_Identity=51.4814814814815, Blast_Score=555, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24651916, Length=553, Percent_Identity=50.8137432188065, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24651914, Length=553, Percent_Identity=50.8137432188065, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI17737445, Length=553, Percent_Identity=50.8137432188065, Blast_Score=559, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59715; Mature: 59583

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVT
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCEECCHHHHHH
EETVRLLVALAEARGLPERRAAMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPE
HHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCCEEEEEEEECCCCCEEEECCCCCCHH
VHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSDLGPAMAYRALRAYAIRDLAF
HHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHEEECCCCCCCCHHHHHHHHHHHHHHHHHH
RFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVAR
HHHHCCCCHHHHHHHHCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFR
HHHEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
EMDEHFRDAPLERNLPALIGLIGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHCCCC
KRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTHLVACDFIGFCQPLHALGRHH
CEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCH
DLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGAL
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
VALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRY
HHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
RARRGG
HHHCCC
>Mature Secondary Structure 
PDRTGPLLRTPAWRALEAHLAELQPLHLRELFARDPGRGERLVADGAGLHLDYSKQRVT
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCEECCHHHHHH
EETVRLLVALAEARGLPERRAAMFRGEKVNVTEGRAVLHVALRAPRGERILVDGNDVVPE
HHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCCEEEEEEEECCCCCEEEECCCCCCHH
VHAVLDRMAAFADQVRSGAWTGFTGKRIRTVVNVGIGGSDLGPAMAYRALRAYAIRDLAF
HHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHEEECCCCCCCCHHHHHHHHHHHHHHHHHH
RFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARSWLLAALGDPRAVAR
HHHHCCCCHHHHHHHHCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPEGFRELLAGFR
HHHEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
EMDEHFRDAPLERNLPALIGLIGVWNANLLGAGTVAVLPYDQYLDRFPAYLQQLTMESNG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHCCCC
KRVTASGTPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTHLVACDFIGFCQPLHALGRHH
CEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCH
DLLMANLFAQGEALAFGKTAEEARAEGTPEPLVPHRTFPGNRPSSTILSDRLTPRTLGAL
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
VALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELESPAEPALAHDGSTNALIRRY
HHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
RARRGG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA