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The map label for this gene is pyc [H]

Identifier: 220918312

GI number: 220918312

Start: 3565659

End: 3569105

Strand: Reverse

Name: pyc [H]

Synonym: A2cp1_3215

Alternate gene names: 220918312

Gene position: 3569105-3565659 (Counterclockwise)

Preceding gene: 220918313

Following gene: 220918310

Centisome position: 70.97

GC content: 70.44

Gene sequence:

>3447_bases
ATGACGATCCCGTTCAAGCGCGTGATGGCAGCGAACCGCGGCGAGATCGCGATCCGGATCTTCCGAGCCTGCACCGAGCT
CGGCATCCAGACCGTCGCGATCTACTCGGAGGAGGACCGCCTCTCGCTGCACCGCTACAAGGCCGACGAGGCCTACCTGG
TGGGCAAGGGGAAGCCGCCCATCGACGCCTACCTCGGCATCGAGGAGATCGTGGAGCTGGCGAGGCGGCTGGAGGTGGAC
GCGATCCACCCCGGCTACGGCTTCCTCTCGGAGAACCCGGAGTTCTCCGAGGCGTGCGAGCGCGCCGGCATCGCGTTCGT
CGGCCCGACCTCCGAGATGCAGCGCAAGCTGGGCGACAAGGTGGCCGGCCGCAAGGCCGCGCAGGCCGCCGGCGTGCCGG
TGGTCCCCGGCACCCCCGAGCCCATCCTCCACGACGAGGAGGCGCTCATCTTCGCGAAGCAGCACGGCTACCCCATCATC
ATCAAGGCGAGCGCCGGCGGCGGCGGCCGCGGCATGCGCGTGGCGCGCAGCCAGAAGGAGCTGCTGGAGGGGCTGGTCTC
GGCGCGCAGCGAGGCGCGCGCCGCGTTCGGCAACGCGGCGGTGTTCCTGGAGCGCTACATCGAGCGCCCCAAGCACATCG
AGGTCCAGGTGCTGGGCGACCACCACGGCGAGCTCGTCCACCTGTTCGAGCGCGACTGCTCCATCCAGCGCCGCCACCAG
AAGGTGGTCGAGTTCGCCCCCTCGCTCGCGCTCACCGAGGCGCAGCGCGAGGCGATCTGCGGCGACGCGCTGAAGATCGC
GCGGTCGGTGCGCTACCGGAACGCCGGCACGGTGGAGTTCCTGGTGGACCCGCAGGGGCGCCACTACTTCATCGAGGTCA
ACCCGCGCATCCAGGTGGAGCACACGGTCACCGAGAGCATCACCGGCCGGAACCTGGTGCAGGCGCAGCTCCTGGTGGCG
CAGGGCAGGCGGCTCTCCGACCCGGAGATCGGGATCGCGCGGCAGCAGGACGTGCAGCGGCGCGGGTTCGCGGTGCAGTG
CCGCATCACCACCGAGGACCCGCAGAACGGCTTCGCGCCGGACTACGGCGTGCTGAAGGCGTACCGCTCGCCGGGCGGCT
TCGGCGTGCGGCTCGACGCGGGCTCGGCGTTCACCGGCGCGGTGATCACGCCGCACTACGACTCGCTGCTGGTGAAGATC
ACGACCTGGGGGCTGACGCTCGACGCCGCGGCGCACGTGATGGACCGGTCGCTGCAGGAGTTCCGCGTCCGCGGCGTCAA
GACGAACATCGCGTTCCTCGAGAACGTGATGCGGCACCCGGTGTTCCTGTCCGGCCGCTGCGACACCTCCTTCATCGAGG
ACCACCCCGAGCTGCTGGCGCAGTCGGAGCGCAAGGACCGCGGGACGAAGCTGCTGCGCTACCTCGCCGACGTGACCGTG
AACGGCTCGCCCGGCGTGTCGCGCGCCACGCGTCCGGCGGACATCCGTGAGCCGCGCCTGCCGAAGGTGGACCTGACCCG
GCCGCGGCCCAAGGGCACCCGCGACATCCTGCTGGAGCGCGGTCCGGAGGGGCTGGCGCGCTGGGTGCTCGCCGAGAAGC
GGCTGCTGTTCACCGACACGACCATGCGCGACGCGCACCAGTCGCTGCTCGCGACGCGGGTGCGCACCCACGACCTGCTC
CGCATCGCGCCCGCGACCGGCGTGCTCGGCGCCGGGCTGTTCTCGCTGGAGATGTGGGGCGGCGCCACGTTCGACGTGGC
GATGCGCTTCCTGCGCGAGGATCCCTGGGAGCGGCTGCACAAGCTGCGCAAGGAGGTCCCGAACGTCCTGTTCCAGATGC
TGCTCCGCGGCTCGAACGCGGTCGGCTACACAAACTATCCCGACAACGTGGTCGAGCGCTTCGTGGAGGAGGCGGCGAGG
TCGGGGATCGACGTGTTCCGCGTGTTCGACTCGCTGAACTGGACCCGGGGCATGAAGGTCGCCATGGAGGCGGTGCGCCG
GCAGGGCAAGGTGTGCGAGGCGGCCGTCTGCTACACGGGCGACATCGACGACCCGAGGCGCGACAAGTACCCGCTCGATT
ACTACGTGAAGCTCGCGAAGGAGCTGGAGCGGATGGGCGCCCACTTCCTCGCGGTGAAGGACATGGCGGGCCTGCTGAAG
CCATTCGCGGCCGCGAAGCTGGTGAAGGCGCTGAAGGACGCCGTCGGCCTGCCGGTGCACCTGCACACGCACGACACCTC
CGGCGTGGCCTCCGCCACGCTGCTCGAGGCGACGAAGGCCGGCGTGGACGTGGTCGACGCGGCGCTGTCGCCGCTCTCCG
GCCTCACGGCGCAGCCGAACCTGAACTCGCTCGCGGCCGTGCTGGAGGGGAGCGCCTGGGACCCGAAGCTCGATCGCGAC
GGGCTGCAGCAGCTCGCGAACTACTGGGAGACGGTGCGGGACTGGTACGCGCCGTTCGAGTCGGGCCTGAAGAGCGGGAC
GGCCGAGGTCTACCGGCACGAGATCCCGGGCGGCCAGTACTCCAACTACAAGCCGCAGGTGGCCGGGCTGGGCCTCCTCG
ACAGGTGGGAGGAGTGCAAGGACATGTACCGGAAGGTGAACCTGCTGTTCGGGGACATCGTGAAGGTGACGCCGTCGTCG
AAGGTGGTCGGCGACATGGCCATGTTCCTGGTGAAGAACGGGCTCGAGCCGGAGGACCTGTTCACCGACAAGGCGAACGA
GCTCGCGTTCCCGGAGTCGGTGGTGGGGCTCGCCCGCGGCATGCTCGGCCAGCTGCACGGCGGGTTCCCGGAGCGGCTGC
GCGAGATCCTGCTCCGCGGCCAGGAGCCCATCACCTGCCGCCCGGGCGAGCTGCTCGAGCCGGCCGACCTCGAGGCCGAG
CGGCGCAGGGCGGCGGAGCGGGTGGGGCACCCGGTGGACGACAAGGCGCTCGTGTCCTGGCTGCTCTACCCGAACGTCTG
GCCGGAGCTCTCGCGCCACCGCGAGGCGTTCTCCGACACCTCGGTGGTCCCGACGCCGGTGTTCTTCTGGGGCCTCGAGC
CCGGCCAGGAGACCAGCGTCGAGATCGAGCCCGGCAAGACGCTCATCGTGAAGCTGGTCTCGATGGGCAAGCTGGAGAAG
GACGGGACCCGAGACCTGATCTTCGAGCTGAACGGCGAGGGGCGCACCATCACGGTGCGCGACGCCTCGGCCGCGCAGGC
GTCGGCGGCGCGGGTGAAGGCGGAGCGCGGCAACCCGGCGCACGTGGGCGCGCCCATGCCGGGCAAGGTGCTGAAGGTGA
ACGTGAAGCCGGGCGACGAGGTGAAGGCCGGCGCCGTGCTGCTCGTCACCGAGGCGATGAAGATGGAGACGAACGTCAAG
GCGAAGGGCGACTGCCGCGTCGCCGAGGTCCGCTTCAAGGAGGGTGACAAGGTCGAGAAGGAGGACCTGCTGCTCGTCCT
CGGGTGA

Upstream 100 bases:

>100_bases
CTCGCCCGCCCCGAGCGGACGGCGATCGCCATCGACCCTCGACCCCGCCAACGGCGCACGCCTCGCGTGCGCGCGCCGCC
CCGTCGTCCCGGAGCCCGAC

Downstream 100 bases:

>100_bases
TCGCCGGCTGAAACGTGAGGGGCGGCCCCCGCGCGGAGCCGCCCCTCACCCCCGTCCGTGCACTACGGCCGGTACACCCC
GCCGTCGAGCGGCTTCGCCG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1147

Protein sequence:

>1148_residues
MTIPFKRVMAANRGEIAIRIFRACTELGIQTVAIYSEEDRLSLHRYKADEAYLVGKGKPPIDAYLGIEEIVELARRLEVD
AIHPGYGFLSENPEFSEACERAGIAFVGPTSEMQRKLGDKVAGRKAAQAAGVPVVPGTPEPILHDEEALIFAKQHGYPII
IKASAGGGGRGMRVARSQKELLEGLVSARSEARAAFGNAAVFLERYIERPKHIEVQVLGDHHGELVHLFERDCSIQRRHQ
KVVEFAPSLALTEAQREAICGDALKIARSVRYRNAGTVEFLVDPQGRHYFIEVNPRIQVEHTVTESITGRNLVQAQLLVA
QGRRLSDPEIGIARQQDVQRRGFAVQCRITTEDPQNGFAPDYGVLKAYRSPGGFGVRLDAGSAFTGAVITPHYDSLLVKI
TTWGLTLDAAAHVMDRSLQEFRVRGVKTNIAFLENVMRHPVFLSGRCDTSFIEDHPELLAQSERKDRGTKLLRYLADVTV
NGSPGVSRATRPADIREPRLPKVDLTRPRPKGTRDILLERGPEGLARWVLAEKRLLFTDTTMRDAHQSLLATRVRTHDLL
RIAPATGVLGAGLFSLEMWGGATFDVAMRFLREDPWERLHKLRKEVPNVLFQMLLRGSNAVGYTNYPDNVVERFVEEAAR
SGIDVFRVFDSLNWTRGMKVAMEAVRRQGKVCEAAVCYTGDIDDPRRDKYPLDYYVKLAKELERMGAHFLAVKDMAGLLK
PFAAAKLVKALKDAVGLPVHLHTHDTSGVASATLLEATKAGVDVVDAALSPLSGLTAQPNLNSLAAVLEGSAWDPKLDRD
GLQQLANYWETVRDWYAPFESGLKSGTAEVYRHEIPGGQYSNYKPQVAGLGLLDRWEECKDMYRKVNLLFGDIVKVTPSS
KVVGDMAMFLVKNGLEPEDLFTDKANELAFPESVVGLARGMLGQLHGGFPERLREILLRGQEPITCRPGELLEPADLEAE
RRRAAERVGHPVDDKALVSWLLYPNVWPELSRHREAFSDTSVVPTPVFFWGLEPGQETSVEIEPGKTLIVKLVSMGKLEK
DGTRDLIFELNGEGRTITVRDASAAQASAARVKAERGNPAHVGAPMPGKVLKVNVKPGDEVKAGAVLLVTEAMKMETNVK
AKGDCRVAEVRFKEGDKVEKEDLLLVLG

Sequences:

>Translated_1148_residues
MTIPFKRVMAANRGEIAIRIFRACTELGIQTVAIYSEEDRLSLHRYKADEAYLVGKGKPPIDAYLGIEEIVELARRLEVD
AIHPGYGFLSENPEFSEACERAGIAFVGPTSEMQRKLGDKVAGRKAAQAAGVPVVPGTPEPILHDEEALIFAKQHGYPII
IKASAGGGGRGMRVARSQKELLEGLVSARSEARAAFGNAAVFLERYIERPKHIEVQVLGDHHGELVHLFERDCSIQRRHQ
KVVEFAPSLALTEAQREAICGDALKIARSVRYRNAGTVEFLVDPQGRHYFIEVNPRIQVEHTVTESITGRNLVQAQLLVA
QGRRLSDPEIGIARQQDVQRRGFAVQCRITTEDPQNGFAPDYGVLKAYRSPGGFGVRLDAGSAFTGAVITPHYDSLLVKI
TTWGLTLDAAAHVMDRSLQEFRVRGVKTNIAFLENVMRHPVFLSGRCDTSFIEDHPELLAQSERKDRGTKLLRYLADVTV
NGSPGVSRATRPADIREPRLPKVDLTRPRPKGTRDILLERGPEGLARWVLAEKRLLFTDTTMRDAHQSLLATRVRTHDLL
RIAPATGVLGAGLFSLEMWGGATFDVAMRFLREDPWERLHKLRKEVPNVLFQMLLRGSNAVGYTNYPDNVVERFVEEAAR
SGIDVFRVFDSLNWTRGMKVAMEAVRRQGKVCEAAVCYTGDIDDPRRDKYPLDYYVKLAKELERMGAHFLAVKDMAGLLK
PFAAAKLVKALKDAVGLPVHLHTHDTSGVASATLLEATKAGVDVVDAALSPLSGLTAQPNLNSLAAVLEGSAWDPKLDRD
GLQQLANYWETVRDWYAPFESGLKSGTAEVYRHEIPGGQYSNYKPQVAGLGLLDRWEECKDMYRKVNLLFGDIVKVTPSS
KVVGDMAMFLVKNGLEPEDLFTDKANELAFPESVVGLARGMLGQLHGGFPERLREILLRGQEPITCRPGELLEPADLEAE
RRRAAERVGHPVDDKALVSWLLYPNVWPELSRHREAFSDTSVVPTPVFFWGLEPGQETSVEIEPGKTLIVKLVSMGKLEK
DGTRDLIFELNGEGRTITVRDASAAQASAARVKAERGNPAHVGAPMPGKVLKVNVKPGDEVKAGAVLLVTEAMKMETNVK
AKGDCRVAEVRFKEGDKVEKEDLLLVLG
>Mature_1147_residues
TIPFKRVMAANRGEIAIRIFRACTELGIQTVAIYSEEDRLSLHRYKADEAYLVGKGKPPIDAYLGIEEIVELARRLEVDA
IHPGYGFLSENPEFSEACERAGIAFVGPTSEMQRKLGDKVAGRKAAQAAGVPVVPGTPEPILHDEEALIFAKQHGYPIII
KASAGGGGRGMRVARSQKELLEGLVSARSEARAAFGNAAVFLERYIERPKHIEVQVLGDHHGELVHLFERDCSIQRRHQK
VVEFAPSLALTEAQREAICGDALKIARSVRYRNAGTVEFLVDPQGRHYFIEVNPRIQVEHTVTESITGRNLVQAQLLVAQ
GRRLSDPEIGIARQQDVQRRGFAVQCRITTEDPQNGFAPDYGVLKAYRSPGGFGVRLDAGSAFTGAVITPHYDSLLVKIT
TWGLTLDAAAHVMDRSLQEFRVRGVKTNIAFLENVMRHPVFLSGRCDTSFIEDHPELLAQSERKDRGTKLLRYLADVTVN
GSPGVSRATRPADIREPRLPKVDLTRPRPKGTRDILLERGPEGLARWVLAEKRLLFTDTTMRDAHQSLLATRVRTHDLLR
IAPATGVLGAGLFSLEMWGGATFDVAMRFLREDPWERLHKLRKEVPNVLFQMLLRGSNAVGYTNYPDNVVERFVEEAARS
GIDVFRVFDSLNWTRGMKVAMEAVRRQGKVCEAAVCYTGDIDDPRRDKYPLDYYVKLAKELERMGAHFLAVKDMAGLLKP
FAAAKLVKALKDAVGLPVHLHTHDTSGVASATLLEATKAGVDVVDAALSPLSGLTAQPNLNSLAAVLEGSAWDPKLDRDG
LQQLANYWETVRDWYAPFESGLKSGTAEVYRHEIPGGQYSNYKPQVAGLGLLDRWEECKDMYRKVNLLFGDIVKVTPSSK
VVGDMAMFLVKNGLEPEDLFTDKANELAFPESVVGLARGMLGQLHGGFPERLREILLRGQEPITCRPGELLEPADLEAER
RRAAERVGHPVDDKALVSWLLYPNVWPELSRHREAFSDTSVVPTPVFFWGLEPGQETSVEIEPGKTLIVKLVSMGKLEKD
GTRDLIFELNGEGRTITVRDASAAQASAARVKAERGNPAHVGAPMPGKVLKVNVKPGDEVKAGAVLLVTEAMKMETNVKA
KGDCRVAEVRFKEGDKVEKEDLLLVLG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1148, Percent_Identity=51.5679442508711, Blast_Score=1124, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1148, Percent_Identity=51.5679442508711, Blast_Score=1124, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1148, Percent_Identity=51.5679442508711, Blast_Score=1124, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=459, Percent_Identity=42.9193899782135, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI189095269, Length=469, Percent_Identity=42.4307036247335, Blast_Score=356, Evalue=8e-98,
Organism=Homo sapiens, GI65506442, Length=469, Percent_Identity=42.4307036247335, Blast_Score=355, Evalue=1e-97,
Organism=Homo sapiens, GI295821183, Length=469, Percent_Identity=42.4307036247335, Blast_Score=355, Evalue=2e-97,
Organism=Homo sapiens, GI38679960, Length=541, Percent_Identity=31.0536044362292, Blast_Score=236, Evalue=1e-61,
Organism=Homo sapiens, GI38679977, Length=541, Percent_Identity=31.0536044362292, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679967, Length=541, Percent_Identity=31.0536044362292, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679974, Length=541, Percent_Identity=31.0536044362292, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679971, Length=541, Percent_Identity=31.0536044362292, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI134142062, Length=516, Percent_Identity=32.1705426356589, Blast_Score=231, Evalue=3e-60,
Organism=Escherichia coli, GI1789654, Length=448, Percent_Identity=46.4285714285714, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17562816, Length=1146, Percent_Identity=52.2687609075044, Blast_Score=1183, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=464, Percent_Identity=43.75, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17567343, Length=456, Percent_Identity=41.4473684210526, Blast_Score=327, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI133931226, Length=491, Percent_Identity=30.142566191446, Blast_Score=204, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71997168, Length=441, Percent_Identity=31.5192743764172, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=441, Percent_Identity=31.5192743764172, Blast_Score=200, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1156, Percent_Identity=50.6920415224914, Blast_Score=1115, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1156, Percent_Identity=50.7785467128028, Blast_Score=1107, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=38.4955752212389, Blast_Score=308, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=32.03125, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6323863, Length=472, Percent_Identity=31.7796610169492, Blast_Score=207, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24652212, Length=1151, Percent_Identity=50.8253692441355, Blast_Score=1131, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1151, Percent_Identity=50.8253692441355, Blast_Score=1131, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1151, Percent_Identity=50.8253692441355, Blast_Score=1131, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1151, Percent_Identity=50.8253692441355, Blast_Score=1131, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1151, Percent_Identity=50.8253692441355, Blast_Score=1131, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1168, Percent_Identity=50.2568493150685, Blast_Score=1121, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1168, Percent_Identity=50.2568493150685, Blast_Score=1121, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1168, Percent_Identity=50.2568493150685, Blast_Score=1121, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1168, Percent_Identity=50.2568493150685, Blast_Score=1121, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1168, Percent_Identity=50.2568493150685, Blast_Score=1121, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=458, Percent_Identity=41.0480349344978, Blast_Score=356, Evalue=5e-98,
Organism=Drosophila melanogaster, GI24651759, Length=419, Percent_Identity=40.8114558472554, Blast_Score=317, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24586458, Length=516, Percent_Identity=30.6201550387597, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI161076409, Length=516, Percent_Identity=30.6201550387597, Blast_Score=223, Evalue=6e-58,
Organism=Drosophila melanogaster, GI161076407, Length=516, Percent_Identity=30.6201550387597, Blast_Score=223, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24586460, Length=516, Percent_Identity=30.6201550387597, Blast_Score=223, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126877; Mature: 126746

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPFKRVMAANRGEIAIRIFRACTELGIQTVAIYSEEDRLSLHRYKADEAYLVGKGKPP
CCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCEEEEECCCCC
IDAYLGIEEIVELARRLEVDAIHPGYGFLSENPEFSEACERAGIAFVGPTSEMQRKLGDK
HHHHCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHH
VAGRKAAQAAGVPVVPGTPEPILHDEEALIFAKQHGYPIIIKASAGGGGRGMRVARSQKE
HHCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHH
LLEGLVSARSEARAAFGNAAVFLERYIERPKHIEVQVLGDHHGELVHLFERDCSIQRRHQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHH
KVVEFAPSLALTEAQREAICGDALKIARSVRYRNAGTVEFLVDPQGRHYFIEVNPRIQVE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCEEEEE
HTVTESITGRNLVQAQLLVAQGRRLSDPEIGIARQQDVQRRGFAVQCRITTEDPQNGFAP
EEHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCC
DYGVLKAYRSPGGFGVRLDAGSAFTGAVITPHYDSLLVKITTWGLTLDAAAHVMDRSLQE
CHHHHHHHCCCCCEEEEEECCCCCCCCEECCCCCCEEEEEEECCEEHHHHHHHHHHHHHH
FRVRGVKTNIAFLENVMRHPVFLSGRCDTSFIEDHPELLAQSERKDRGTKLLRYLADVTV
HHHHCCHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEE
NGSPGVSRATRPADIREPRLPKVDLTRPRPKGTRDILLERGPEGLARWVLAEKRLLFTDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECC
TMRDAHQSLLATRVRTHDLLRIAPATGVLGAGLFSLEMWGGATFDVAMRFLREDPWERLH
HHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCHHEEECCCCCHHHHHHHHHHCCHHHHHH
KLRKEVPNVLFQMLLRGSNAVGYTNYPDNVVERFVEEAARSGIDVFRVFDSLNWTRGMKV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHH
AMEAVRRQGKVCEAAVCYTGDIDDPRRDKYPLDYYVKLAKELERMGAHFLAVKDMAGLLK
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PFAAAKLVKALKDAVGLPVHLHTHDTSGVASATLLEATKAGVDVVDAALSPLSGLTAQPN
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCC
LNSLAAVLEGSAWDPKLDRDGLQQLANYWETVRDWYAPFESGLKSGTAEVYRHEIPGGQY
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
SNYKPQVAGLGLLDRWEECKDMYRKVNLLFGDIVKVTPSSKVVGDMAMFLVKNGLEPEDL
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHH
FTDKANELAFPESVVGLARGMLGQLHGGFPERLREILLRGQEPITCRPGELLEPADLEAE
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RRRAAERVGHPVDDKALVSWLLYPNVWPELSRHREAFSDTSVVPTPVFFWGLEPGQETSV
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
EIEPGKTLIVKLVSMGKLEKDGTRDLIFELNGEGRTITVRDASAAQASAARVKAERGNPA
EECCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCC
HVGAPMPGKVLKVNVKPGDEVKAGAVLLVTEAMKMETNVKAKGDCRVAEVRFKEGDKVEK
CCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
EDLLLVLG
CCEEEEEC
>Mature Secondary Structure 
TIPFKRVMAANRGEIAIRIFRACTELGIQTVAIYSEEDRLSLHRYKADEAYLVGKGKPP
CCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCEEEEECCCCC
IDAYLGIEEIVELARRLEVDAIHPGYGFLSENPEFSEACERAGIAFVGPTSEMQRKLGDK
HHHHCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHH
VAGRKAAQAAGVPVVPGTPEPILHDEEALIFAKQHGYPIIIKASAGGGGRGMRVARSQKE
HHCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHH
LLEGLVSARSEARAAFGNAAVFLERYIERPKHIEVQVLGDHHGELVHLFERDCSIQRRHQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHH
KVVEFAPSLALTEAQREAICGDALKIARSVRYRNAGTVEFLVDPQGRHYFIEVNPRIQVE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCEEEEE
HTVTESITGRNLVQAQLLVAQGRRLSDPEIGIARQQDVQRRGFAVQCRITTEDPQNGFAP
EEHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCC
DYGVLKAYRSPGGFGVRLDAGSAFTGAVITPHYDSLLVKITTWGLTLDAAAHVMDRSLQE
CHHHHHHHCCCCCEEEEEECCCCCCCCEECCCCCCEEEEEEECCEEHHHHHHHHHHHHHH
FRVRGVKTNIAFLENVMRHPVFLSGRCDTSFIEDHPELLAQSERKDRGTKLLRYLADVTV
HHHHCCHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEE
NGSPGVSRATRPADIREPRLPKVDLTRPRPKGTRDILLERGPEGLARWVLAEKRLLFTDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECC
TMRDAHQSLLATRVRTHDLLRIAPATGVLGAGLFSLEMWGGATFDVAMRFLREDPWERLH
HHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCHHEEECCCCCHHHHHHHHHHCCHHHHHH
KLRKEVPNVLFQMLLRGSNAVGYTNYPDNVVERFVEEAARSGIDVFRVFDSLNWTRGMKV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHH
AMEAVRRQGKVCEAAVCYTGDIDDPRRDKYPLDYYVKLAKELERMGAHFLAVKDMAGLLK
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PFAAAKLVKALKDAVGLPVHLHTHDTSGVASATLLEATKAGVDVVDAALSPLSGLTAQPN
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCC
LNSLAAVLEGSAWDPKLDRDGLQQLANYWETVRDWYAPFESGLKSGTAEVYRHEIPGGQY
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
SNYKPQVAGLGLLDRWEECKDMYRKVNLLFGDIVKVTPSSKVVGDMAMFLVKNGLEPEDL
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHH
FTDKANELAFPESVVGLARGMLGQLHGGFPERLREILLRGQEPITCRPGELLEPADLEAE
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RRRAAERVGHPVDDKALVSWLLYPNVWPELSRHREAFSDTSVVPTPVFFWGLEPGQETSV
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
EIEPGKTLIVKLVSMGKLEKDGTRDLIFELNGEGRTITVRDASAAQASAARVKAERGNPA
EECCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCC
HVGAPMPGKVLKVNVKPGDEVKAGAVLLVTEAMKMETNVKAKGDCRVAEVRFKEGDKVEK
CCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
EDLLLVLG
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]