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The map label for this gene is fliD [H]

Identifier: 220917711

GI number: 220917711

Start: 2888328

End: 2889683

Strand: Direct

Name: fliD [H]

Synonym: A2cp1_2612

Alternate gene names: 220917711

Gene position: 2888328-2889683 (Clockwise)

Preceding gene: 220917710

Following gene: 220917712

Centisome position: 57.43

GC content: 74.63

Gene sequence:

>1356_bases
ATGGACGCATCGTTCCGCGCGGGCGGTCTCGCCTCGGGGATGGACACCAACGCAATCGTCGAAAAGCTCGTCGAGCTGGA
GTCGCGGCCGCTCGGCCTCCTCCGGCAGCGGCAGGCCGCGTTCCGCACGCAGATCTCCGCGCTGGGCGACGTCATCTCCG
GGCTGTCCACCCTCTCCGCCGCCGCCGCCGACCTGGGCGCTCACGGCGTCCTCTCCACCCAGGCGCGCTCCAGCCCGAAG
TCCTTCTCGGCCGCCCCGGGGACGGACGCGGTCGCCGGCAGCTACCGGGTGGCGGTGAAGGCGCTGGCGCGCCCGGCCAA
GTGGCGCTCGGACGCGTTCGCCGACGGCGTCGGCGTGGCCGGCGGGACGCTCCGCCTGACCGTCCAGGGCACGGCCTTCC
CCCCCATCGCCGTCGCGGACGGCACCAGCCTCGCCGACGTGGCCTACGCCATCCGTCAGAGCGGGGCGCCGGTGTCCGCG
GTGGTGCTCGACGACGGCACGTCGTCCTGGCTCTCCGTGACCGCCCGCGACACCGGCCACCCGCCGGGCGGCGCGCCCGC
GGACGCGCTGTCCATCGCCTTCACCCCGGACGCCGGCGCCACCGGCCAGGCGCCGGGCCTCGCGGAGATCGAGGCCGCGC
GCAACGCGCAGGTGGAGGTCGACGGCCTGACGTTCACCCGGACGGGCAACGTGATCGCCGACGCGCTGCCGGGGGTGACG
CTCACGCTCACGAGCGAGGGCGGCCCGGCGGAGGACCTGGTGCTCGGGACCGATCCGGACGGCACCCAGGCGCGGCTGCA
GAAGCTGGTGGACGCCTACAACGGCGTGATGCGGCTCGTGCAGCGCCACCTCGCGGTCGCGAAGGACGCCGACCGCGCCA
CCACCCTGGCCGGCGACTCCACCCTGCGCTCGCTGCAGGCCCGGCTCCAGCGCGTGCTGGTGACCGAGGTGCCCGGGCTC
GCGACCGTGCGCACGCTCGCGGACCTGGGCGTCAAGACCGCCCGCGACGGCAGCCTCTCCATCGACGCGACCACGCTCGC
CTCGGCGATCTCGCGCGATCCCGCCGCCGTGAACGCGCTGTTCTCGAACTCGGGGACGGGCCTGGCCGCGGTCGTGAAGT
CGCTCGTGACCGACCACACCCGCGCCGGCGGCGGCACGCTGGTGCTCCGGCAGGAGGGGCTGGGCCGCACGGTGAAGGAC
CTCGACGGCCAGGCCGCCGCGCTGCAGCTCCGCATCGACGCCTTCCAGCAGAACCTGATCCGCCAGTTCACCGCGATGGA
GAACACCGTCAGCGGGCTCAAGTCGATCGGGAGCTTCCTCGCCGGCCAGACCACGCAGCAGCAGAAGGGGAGCTGA

Upstream 100 bases:

>100_bases
ACCAGATGCCGCAGCTCGCGCTGAAGCTGCTCGGGTGATCTCGCGGTGAACTTCGCGCGCCGCTCCCCGGCCACGCGCCG
GGGAGCGGCCGGAGGCCTAC

Downstream 100 bases:

>100_bases
TCGTGACCGCCTGCCTCGCCGCGCCGTGCCCCCGACCCGCCTCGTGCGATCCCGGCGGCCACCTCCGCCGCGCCATCGCG
CTGATGCGCACCGGCGCCGC

Product: flagellar hook-associated 2 domain-containing protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MDASFRAGGLASGMDTNAIVEKLVELESRPLGLLRQRQAAFRTQISALGDVISGLSTLSAAAADLGAHGVLSTQARSSPK
SFSAAPGTDAVAGSYRVAVKALARPAKWRSDAFADGVGVAGGTLRLTVQGTAFPPIAVADGTSLADVAYAIRQSGAPVSA
VVLDDGTSSWLSVTARDTGHPPGGAPADALSIAFTPDAGATGQAPGLAEIEAARNAQVEVDGLTFTRTGNVIADALPGVT
LTLTSEGGPAEDLVLGTDPDGTQARLQKLVDAYNGVMRLVQRHLAVAKDADRATTLAGDSTLRSLQARLQRVLVTEVPGL
ATVRTLADLGVKTARDGSLSIDATTLASAISRDPAAVNALFSNSGTGLAAVVKSLVTDHTRAGGGTLVLRQEGLGRTVKD
LDGQAAALQLRIDAFQQNLIRQFTAMENTVSGLKSIGSFLAGQTTQQQKGS

Sequences:

>Translated_451_residues
MDASFRAGGLASGMDTNAIVEKLVELESRPLGLLRQRQAAFRTQISALGDVISGLSTLSAAAADLGAHGVLSTQARSSPK
SFSAAPGTDAVAGSYRVAVKALARPAKWRSDAFADGVGVAGGTLRLTVQGTAFPPIAVADGTSLADVAYAIRQSGAPVSA
VVLDDGTSSWLSVTARDTGHPPGGAPADALSIAFTPDAGATGQAPGLAEIEAARNAQVEVDGLTFTRTGNVIADALPGVT
LTLTSEGGPAEDLVLGTDPDGTQARLQKLVDAYNGVMRLVQRHLAVAKDADRATTLAGDSTLRSLQARLQRVLVTEVPGL
ATVRTLADLGVKTARDGSLSIDATTLASAISRDPAAVNALFSNSGTGLAAVVKSLVTDHTRAGGGTLVLRQEGLGRTVKD
LDGQAAALQLRIDAFQQNLIRQFTAMENTVSGLKSIGSFLAGQTTQQQKGS
>Mature_451_residues
MDASFRAGGLASGMDTNAIVEKLVELESRPLGLLRQRQAAFRTQISALGDVISGLSTLSAAAADLGAHGVLSTQARSSPK
SFSAAPGTDAVAGSYRVAVKALARPAKWRSDAFADGVGVAGGTLRLTVQGTAFPPIAVADGTSLADVAYAIRQSGAPVSA
VVLDDGTSSWLSVTARDTGHPPGGAPADALSIAFTPDAGATGQAPGLAEIEAARNAQVEVDGLTFTRTGNVIADALPGVT
LTLTSEGGPAEDLVLGTDPDGTQARLQKLVDAYNGVMRLVQRHLAVAKDADRATTLAGDSTLRSLQARLQRVLVTEVPGL
ATVRTLADLGVKTARDGSLSIDATTLASAISRDPAAVNALFSNSGTGLAAVVKSLVTDHTRAGGGTLVLRQEGLGRTVKD
LDGQAAALQLRIDAFQQNLIRQFTAMENTVSGLKSIGSFLAGQTTQQQKGS

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=463, Percent_Identity=29.1576673866091, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 45940; Mature: 45940

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASFRAGGLASGMDTNAIVEKLVELESRPLGLLRQRQAAFRTQISALGDVISGLSTLSA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAADLGAHGVLSTQARSSPKSFSAAPGTDAVAGSYRVAVKALARPAKWRSDAFADGVGVA
HHHHHCCCCEEECHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCC
GGTLRLTVQGTAFPPIAVADGTSLADVAYAIRQSGAPVSAVVLDDGTSSWLSVTARDTGH
CCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCC
PPGGAPADALSIAFTPDAGATGQAPGLAEIEAARNAQVEVDGLTFTRTGNVIADALPGVT
CCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEEEECCEEEEECCCHHHHCCCCEE
LTLTSEGGPAEDLVLGTDPDGTQARLQKLVDAYNGVMRLVQRHLAVAKDADRATTLAGDS
EEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCHH
TLRSLQARLQRVLVTEVPGLATVRTLADLGVKTARDGSLSIDATTLASAISRDPAAVNAL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHH
FSNSGTGLAAVVKSLVTDHTRAGGGTLVLRQEGLGRTVKDLDGQAAALQLRIDAFQQNLI
HCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCCEEEEEEHHHHHHHHHH
RQFTAMENTVSGLKSIGSFLAGQTTQQQKGS
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MDASFRAGGLASGMDTNAIVEKLVELESRPLGLLRQRQAAFRTQISALGDVISGLSTLSA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAADLGAHGVLSTQARSSPKSFSAAPGTDAVAGSYRVAVKALARPAKWRSDAFADGVGVA
HHHHHCCCCEEECHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCC
GGTLRLTVQGTAFPPIAVADGTSLADVAYAIRQSGAPVSAVVLDDGTSSWLSVTARDTGH
CCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCC
PPGGAPADALSIAFTPDAGATGQAPGLAEIEAARNAQVEVDGLTFTRTGNVIADALPGVT
CCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCEEEECCEEEEECCCHHHHCCCCEE
LTLTSEGGPAEDLVLGTDPDGTQARLQKLVDAYNGVMRLVQRHLAVAKDADRATTLAGDS
EEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCHH
TLRSLQARLQRVLVTEVPGLATVRTLADLGVKTARDGSLSIDATTLASAISRDPAAVNAL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHH
FSNSGTGLAAVVKSLVTDHTRAGGGTLVLRQEGLGRTVKDLDGQAAALQLRIDAFQQNLI
HCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCCEEEEEEHHHHHHHHHH
RQFTAMENTVSGLKSIGSFLAGQTTQQQKGS
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10678962; 10984043 [H]