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The map label for this gene is cheW [H]

Identifier: 220917677

GI number: 220917677

Start: 2856819

End: 2857403

Strand: Direct

Name: cheW [H]

Synonym: A2cp1_2578

Alternate gene names: 220917677

Gene position: 2856819-2857403 (Clockwise)

Preceding gene: 220917668

Following gene: 220917678

Centisome position: 56.8

GC content: 70.94

Gene sequence:

>585_bases
GTGACGACGGAGCTGGCGAAGGCCGACGGAGCGGCGGGCACGGCCACGGAGCTGGGCCGCCGCCTCGCCGGGAAGTACAT
GACGTTCCAGCTCGCGCGCGAGGAGTACGGGATCGAGATCCTCACCGTGCGCGAGATCATCGGGCTGCTGGAGATGACCC
GCGTGCCGCGCACGCGCGACTTCATCCGCGGGGTCATCAACCTGCGCGGCAAGGTCATCCCGGTCATCGACCTGCGCCTC
AAGTTCGGCATGGAGCGGTGCGAGCCCTCCGATCAGACCGTGATCATCGTGGTGCACTGCGCGGTGGACGGGAGGCCGCT
CACCATGGGCCTGCTGGTGGATCAGGTGCTCGAGGTCCTCTCCATCGGCCCGGCGATGATCGAGCCGACGCCCGCGCTCG
GGCAGGCCGCGCCGGAGGAGGACTTCATCCTCGGCGTCGGGAAGCACGACCGGCGCATCGTGTTCCTGCTCGACATCGCT
CGGATCCTCTCCTCGGACGACGCCCGCGAGCTGGGCCGCGCGTCCGCCGCCGGCGCGCCCGCCGGCGTCACCCCTGGCCC
CGAGACGACGGGAGACGTGCCATGA

Upstream 100 bases:

>100_bases
GCCCCGCTGGCACGCCGGGTGCTCCATCGCGGCGCGGAGCTCGCGGCGCCAGGACCGCGACGCGGCCGCGACGCCGCGAG
ACGAGACGGGAGGATCGCAC

Downstream 100 bases:

>100_bases
AGACCCGCAACACCAACAACGGGAAGCTCATCTTCGCGGGGTTCCTCGCCGCGAACATCCTGGCGGTCGCCATCGGCGCC
ACCTCCTTCTTCACGGTGCG

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTTELAKADGAAGTATELGRRLAGKYMTFQLAREEYGIEILTVREIIGLLEMTRVPRTRDFIRGVINLRGKVIPVIDLRL
KFGMERCEPSDQTVIIVVHCAVDGRPLTMGLLVDQVLEVLSIGPAMIEPTPALGQAAPEEDFILGVGKHDRRIVFLLDIA
RILSSDDARELGRASAAGAPAGVTPGPETTGDVP

Sequences:

>Translated_194_residues
MTTELAKADGAAGTATELGRRLAGKYMTFQLAREEYGIEILTVREIIGLLEMTRVPRTRDFIRGVINLRGKVIPVIDLRL
KFGMERCEPSDQTVIIVVHCAVDGRPLTMGLLVDQVLEVLSIGPAMIEPTPALGQAAPEEDFILGVGKHDRRIVFLLDIA
RILSSDDARELGRASAAGAPAGVTPGPETTGDVP
>Mature_193_residues
TTELAKADGAAGTATELGRRLAGKYMTFQLAREEYGIEILTVREIIGLLEMTRVPRTRDFIRGVINLRGKVIPVIDLRLK
FGMERCEPSDQTVIIVVHCAVDGRPLTMGLLVDQVLEVLSIGPAMIEPTPALGQAAPEEDFILGVGKHDRRIVFLLDIAR
ILSSDDARELGRASAAGAPAGVTPGPETTGDVP

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=164, Percent_Identity=35.3658536585366, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 20870; Mature: 20738

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTELAKADGAAGTATELGRRLAGKYMTFQLAREEYGIEILTVREIIGLLEMTRVPRTRD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHCEEEEEHHHHHHHHHHHCCCCHHH
FIRGVINLRGKVIPVIDLRLKFGMERCEPSDQTVIIVVHCAVDGRPLTMGLLVDQVLEVL
HHHHHHHCCCCEEEEEEHHHHHCHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
SIGPAMIEPTPALGQAAPEEDFILGVGKHDRRIVFLLDIARILSSDDARELGRASAAGAP
HCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHCCCCHHHHHCCCCCCCC
AGVTPGPETTGDVP
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TTELAKADGAAGTATELGRRLAGKYMTFQLAREEYGIEILTVREIIGLLEMTRVPRTRD
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEHHHHHCEEEEEHHHHHHHHHHHCCCCHHH
FIRGVINLRGKVIPVIDLRLKFGMERCEPSDQTVIIVVHCAVDGRPLTMGLLVDQVLEVL
HHHHHHHCCCCEEEEEEHHHHHCHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
SIGPAMIEPTPALGQAAPEEDFILGVGKHDRRIVFLLDIARILSSDDARELGRASAAGAP
HCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHCCCCHHHHHCCCCCCCC
AGVTPGPETTGDVP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]