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The map label for this gene is glpX [H]

Identifier: 220917408

GI number: 220917408

Start: 2557708

End: 2558673

Strand: Reverse

Name: glpX [H]

Synonym: A2cp1_2308

Alternate gene names: 220917408

Gene position: 2558673-2557708 (Counterclockwise)

Preceding gene: 220917409

Following gene: 220917407

Centisome position: 50.88

GC content: 73.71

Gene sequence:

>966_bases
ATGGATCGGAACCTCGCGCTCGAGGTGGTCCGCGTCACCGAGGCCGCCGCGCTGGCCTCCGCCCGGCTGATGGGGCGCGG
CGACCGCAACGGCGCCGACCAGGCCGCGGTCGAGGCCATGCGCAAGGCCTTCAACGACATCGCCATCCGCGGGGAGGTGG
TGATCGGGGAGGGCGAGCGCGACGAGGCGCCGATGCTTTACATCGGCGAGAAGGTGGGCCGCTGCCGCGACGGCGACGCC
GAGATGGAGATCGCGGTGGACCCGCTGGAGGGCACGAACCTGTGCGCCACCGGGGCCCCCAACGCGCTCAGCGTCATCGC
CATGGGCGAGAAGGGGCGGCTGCTGCGCGCGCCCGACACGTACATGGAGAAGATCGCGGTCGGGCCGCGCGCCCGCGGGG
CGGTGGATCTGCGGCGCACGCCCACCGAGAACCTGCGCCGGGTCGCGGACGCGCTGGGCAAGTACGTCGAGGACCTCACC
GTCGTGATCCTCGACCGGCCCCGCCACGCGAAGCTGGTCCGCGAGGTCCGCGAGGCGGGCGCGCGCATCAAGCTCATCGG
CGACGGCGACGTGGCCGGCGCGCTCAACACCTGCTTCCCGGACACCGGCGTGGACCTGCTGATGGGCGTCGGCGGCGCGC
CCGAGGGCGTGATCGCCGCCGCGGCGCTCCGCTGCGTGGGCGGCGATCTGCAGGGCCGGCTCGTGTTCCGCAACGACGCC
GAGCGCGAGCGGGCCCGCGGGTACGGCGTGAAGGACCTCGACCGGATCATGGGCGCGGAGGAGCTGGCCGGCGGCAACGT
CATGTTCGCCGCGACCGGCGTCACCCACGGCGACTTCCTGAAGGGCGTGCGCTTCACCGGCGACGGCGCGCGGACGCACT
CCGTCGTGATGCGGTCGCGGACCGGGACGCTCCGCTACATCGAGACCGAGCACCACTTCACCCGCAGCCCGGACTACGGC
TGGTAG

Upstream 100 bases:

>100_bases
GCGTGGACCTGGAGGGGCGCGTGCGCCGCATGCCGCCGGAGCTGCTGTCGCGGCTCTCGGTCGGCGAGGCGCCCGCCGGC
CCGGGGAAGGGAGCCTGACC

Downstream 100 bases:

>100_bases
CCCTCAGGAGGCCCCGATGTCGGTCGTCACGCAGGAGGTCGTCATCGACGCGCCCATCGACCGCGTCTACGACGTGATCG
TGGACTACGCGCGCTACCCC

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDRNLALEVVRVTEAAALASARLMGRGDRNGADQAAVEAMRKAFNDIAIRGEVVIGEGERDEAPMLYIGEKVGRCRDGDA
EMEIAVDPLEGTNLCATGAPNALSVIAMGEKGRLLRAPDTYMEKIAVGPRARGAVDLRRTPTENLRRVADALGKYVEDLT
VVILDRPRHAKLVREVREAGARIKLIGDGDVAGALNTCFPDTGVDLLMGVGGAPEGVIAAAALRCVGGDLQGRLVFRNDA
ERERARGYGVKDLDRIMGAEELAGGNVMFAATGVTHGDFLKGVRFTGDGARTHSVVMRSRTGTLRYIETEHHFTRSPDYG
W

Sequences:

>Translated_321_residues
MDRNLALEVVRVTEAAALASARLMGRGDRNGADQAAVEAMRKAFNDIAIRGEVVIGEGERDEAPMLYIGEKVGRCRDGDA
EMEIAVDPLEGTNLCATGAPNALSVIAMGEKGRLLRAPDTYMEKIAVGPRARGAVDLRRTPTENLRRVADALGKYVEDLT
VVILDRPRHAKLVREVREAGARIKLIGDGDVAGALNTCFPDTGVDLLMGVGGAPEGVIAAAALRCVGGDLQGRLVFRNDA
ERERARGYGVKDLDRIMGAEELAGGNVMFAATGVTHGDFLKGVRFTGDGARTHSVVMRSRTGTLRYIETEHHFTRSPDYG
W
>Mature_321_residues
MDRNLALEVVRVTEAAALASARLMGRGDRNGADQAAVEAMRKAFNDIAIRGEVVIGEGERDEAPMLYIGEKVGRCRDGDA
EMEIAVDPLEGTNLCATGAPNALSVIAMGEKGRLLRAPDTYMEKIAVGPRARGAVDLRRTPTENLRRVADALGKYVEDLT
VVILDRPRHAKLVREVREAGARIKLIGDGDVAGALNTCFPDTGVDLLMGVGGAPEGVIAAAALRCVGGDLQGRLVFRNDA
ERERARGYGVKDLDRIMGAEELAGGNVMFAATGVTHGDFLKGVRFTGDGARTHSVVMRSRTGTLRYIETEHHFTRSPDYG
W

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=329, Percent_Identity=50.1519756838906, Blast_Score=295, Evalue=2e-81,
Organism=Escherichia coli, GI1789298, Length=323, Percent_Identity=44.5820433436532, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34470; Mature: 34470

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNLALEVVRVTEAAALASARLMGRGDRNGADQAAVEAMRKAFNDIAIRGEVVIGEGER
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCC
DEAPMLYIGEKVGRCRDGDAEMEIAVDPLEGTNLCATGAPNALSVIAMGEKGRLLRAPDT
CCCCEEEECHHHCCCCCCCCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCEEECCHH
YMEKIAVGPRARGAVDLRRTPTENLRRVADALGKYVEDLTVVILDRPRHAKLVREVREAG
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCC
ARIKLIGDGDVAGALNTCFPDTGVDLLMGVGGAPEGVIAAAALRCVGGDLQGRLVFRNDA
CEEEEEECCCCCCHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
ERERARGYGVKDLDRIMGAEELAGGNVMFAATGVTHGDFLKGVRFTGDGARTHSVVMRSR
HHHHHCCCCHHHHHHHHCHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCHHHHEEEECC
TGTLRYIETEHHFTRSPDYGW
CCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MDRNLALEVVRVTEAAALASARLMGRGDRNGADQAAVEAMRKAFNDIAIRGEVVIGEGER
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCC
DEAPMLYIGEKVGRCRDGDAEMEIAVDPLEGTNLCATGAPNALSVIAMGEKGRLLRAPDT
CCCCEEEECHHHCCCCCCCCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCEEECCHH
YMEKIAVGPRARGAVDLRRTPTENLRRVADALGKYVEDLTVVILDRPRHAKLVREVREAG
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCC
ARIKLIGDGDVAGALNTCFPDTGVDLLMGVGGAPEGVIAAAALRCVGGDLQGRLVFRNDA
CEEEEEECCCCCCHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
ERERARGYGVKDLDRIMGAEELAGGNVMFAATGVTHGDFLKGVRFTGDGARTHSVVMRSR
HHHHHCCCCHHHHHHHHCHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCHHHHEEEECC
TGTLRYIETEHHFTRSPDYGW
CCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]