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The map label for this gene is amiC [H]

Identifier: 220917351

GI number: 220917351

Start: 2498718

End: 2500529

Strand: Direct

Name: amiC [H]

Synonym: A2cp1_2251

Alternate gene names: 220917351

Gene position: 2498718-2500529 (Clockwise)

Preceding gene: 220917347

Following gene: 220917352

Centisome position: 49.68

GC content: 78.75

Gene sequence:

>1812_bases
ATGCGCCGCGCCGCCGTCCTGCTCACCGTGCTGATGCTCGCTGCCCCGGTGGAGGCAGCGCCGGCGGCGCGCTACCGCGG
CAGGACGCCCGCCGCCGCGAAGCACGACGCGCCGCGGCGAACGGCGGCCCGCGCGCGCCCGGCCCCGGCGCCGAAGAAGC
CCGCGGCCCGGGCGAAGGTGAGCCGGCTGGTGGACGCCAAGGCCGCGATGTCCGCGCTGATGCGCGACCGGAACCGGCGC
CGCTACCGCCACAACTGGGAGAAGGCGATCCGCGGGCTCGAGCAGGCGGCGCGCGGGAAGGACGCGCCGGCCGCGCTGCT
CGAGGCGTCCCGCGCGCGGTACGCGCTGTACCGCTGGTCCGCGGTGGAGGCGGATCGCGACGAGGCGCTTCGGCTCGCGG
CGCGCGCGACGCGCCTCGGCTCGCGCGACGCGCCCGCGCTCGCCGCCGCGATCCGCCGCGAGGCCGGCGACGATCGCCCG
GCGCGCGCCGCCGCGCCGCCCCGGGCCGCGCCGAAGCGGGCGCCGACGCCCGCGCCCGCGGCCCCTGCGGCGCCCGAGCC
GGAGCCCGCCGACGCCGACGAGGAGCCCGCCCCGGAGCCCGCGCTCGACGCGGCCCTGGCCGACCTGCGCGGCGAGCCCG
CCCGGCCCATGCCGCTCGGCGAGTCCGGCGGGGAGGGCACGGCCACCGTCTCCGAGGTCCGGGCCTGGTCGAGCGGCGAC
TACACCCGCGTCGCGATCTACTTGTCGCACTGGGTGGGCTGGCACAAGCTGGAGCTCGCCCCGGAGGGCGACCGCCCTCG
CCGGCTCGCGCTCGACCTGCGCCCGGCGCACCTCGACGGCAAGGCGGTCGAGCGCGCCGTGGCCGGCGACCAGGTGGACC
GGGTGCGCGCGGCGCAGAACGGCCCGGACACCGTGCGCGTGGTGCTGGACCTGCCCGGCGACGACAAGGTGCAGCTCTTC
ACGCTCGACGACCCGCCGCGCCTGATCGTGGACGTCGGGACGCACGCCGCCATCCACCAGGCGATCGCCGGGGCGACCCG
CGCGCCGGAGCCGCCGCCGGCGCCCGGCCCGGCCGCGCCCGCGGGCAAGGCCGGCCCGTCCGCCGGCGAGGGCGAGCTCG
GGCCCATCCGTCGCATCGTGGTGGACGCCGGGCACGGCGGCCACGATCCCGGCGCCATCGGCCCGACGCGCGTGCGCGAG
AAGGACGTGACGCTCGCGATCGCGCGGCGGCTGGCGCGCAAGCTGGAGGCCGAGGGCTTCCAGGTGGTGCTGACGCGCCG
CGACGACCGGTTCCTGGCGCTCGAGGAGCGCACCGCGCTCGCGAACACCGCCCGCGGCGACCTGTTCGTCTCGGTGCACG
CGAACGCCCACCCGCGCCGCGTCCGCGCCGGCGTGGAGACCTACTTCCTGAACGTGGCCGACGACCGCTACGCGGCCCGG
CTCGCCGCCCGCGAGAACGGGCTCGACGCCGAGGACGCGCCGTCGGAGGTGGCGCGCATCCTGAGCGACCTCGACGCGAA
GGCCAGCGCCGACAGCTCGCGCCGGCTCGCGCAGCTCGTCCAGCGCGAGGTGTGCGCGGGCGTGCGCTCGAGGGTGGGGG
ACGTGAAGGATCTCGGCGTGAAGAGCGCGCTGTTCTACGTGCTGCTGGGCGCGCGCATGCCGGCGGTGCTGGTCGAGACC
GGGTTCATCTCCAACCGCGCCGAGGAGCAGCGCCTCGGCTCGGCGCGCTACCAGGACGAGGTCGCGTCCGGGATCACCCG
CGCGGTCGCGCAGTTCGCCCGGGGCGACGCGCGGGTCGCGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCAGTGTCCCGGGCCGGTCGGGAATGGCCCCGCGCATGGGATGCGCGCCGGCGGCCGGAAATTGGACGGAGATATCGAGC
GGGGGGACATTCGCCCTCCC

Downstream 100 bases:

>100_bases
GCGCCTCGGGGAGCGGGCGGCGCCCCGCGCGGTGCCCGGTCGCGGAAGCCCTCGACACGGCGGCCGGCCTCCGCTATGCG
TGAACGCTCTCTCCGGGAGC

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRRAAVLLTVLMLAAPVEAAPAARYRGRTPAAAKHDAPRRTAARARPAPAPKKPAARAKVSRLVDAKAAMSALMRDRNRR
RYRHNWEKAIRGLEQAARGKDAPAALLEASRARYALYRWSAVEADRDEALRLAARATRLGSRDAPALAAAIRREAGDDRP
ARAAAPPRAAPKRAPTPAPAAPAAPEPEPADADEEPAPEPALDAALADLRGEPARPMPLGESGGEGTATVSEVRAWSSGD
YTRVAIYLSHWVGWHKLELAPEGDRPRRLALDLRPAHLDGKAVERAVAGDQVDRVRAAQNGPDTVRVVLDLPGDDKVQLF
TLDDPPRLIVDVGTHAAIHQAIAGATRAPEPPPAPGPAAPAGKAGPSAGEGELGPIRRIVVDAGHGGHDPGAIGPTRVRE
KDVTLAIARRLARKLEAEGFQVVLTRRDDRFLALEERTALANTARGDLFVSVHANAHPRRVRAGVETYFLNVADDRYAAR
LAARENGLDAEDAPSEVARILSDLDAKASADSSRRLAQLVQREVCAGVRSRVGDVKDLGVKSALFYVLLGARMPAVLVET
GFISNRAEEQRLGSARYQDEVASGITRAVAQFARGDARVAAAR

Sequences:

>Translated_603_residues
MRRAAVLLTVLMLAAPVEAAPAARYRGRTPAAAKHDAPRRTAARARPAPAPKKPAARAKVSRLVDAKAAMSALMRDRNRR
RYRHNWEKAIRGLEQAARGKDAPAALLEASRARYALYRWSAVEADRDEALRLAARATRLGSRDAPALAAAIRREAGDDRP
ARAAAPPRAAPKRAPTPAPAAPAAPEPEPADADEEPAPEPALDAALADLRGEPARPMPLGESGGEGTATVSEVRAWSSGD
YTRVAIYLSHWVGWHKLELAPEGDRPRRLALDLRPAHLDGKAVERAVAGDQVDRVRAAQNGPDTVRVVLDLPGDDKVQLF
TLDDPPRLIVDVGTHAAIHQAIAGATRAPEPPPAPGPAAPAGKAGPSAGEGELGPIRRIVVDAGHGGHDPGAIGPTRVRE
KDVTLAIARRLARKLEAEGFQVVLTRRDDRFLALEERTALANTARGDLFVSVHANAHPRRVRAGVETYFLNVADDRYAAR
LAARENGLDAEDAPSEVARILSDLDAKASADSSRRLAQLVQREVCAGVRSRVGDVKDLGVKSALFYVLLGARMPAVLVET
GFISNRAEEQRLGSARYQDEVASGITRAVAQFARGDARVAAAR
>Mature_603_residues
MRRAAVLLTVLMLAAPVEAAPAARYRGRTPAAAKHDAPRRTAARARPAPAPKKPAARAKVSRLVDAKAAMSALMRDRNRR
RYRHNWEKAIRGLEQAARGKDAPAALLEASRARYALYRWSAVEADRDEALRLAARATRLGSRDAPALAAAIRREAGDDRP
ARAAAPPRAAPKRAPTPAPAAPAAPEPEPADADEEPAPEPALDAALADLRGEPARPMPLGESGGEGTATVSEVRAWSSGD
YTRVAIYLSHWVGWHKLELAPEGDRPRRLALDLRPAHLDGKAVERAVAGDQVDRVRAAQNGPDTVRVVLDLPGDDKVQLF
TLDDPPRLIVDVGTHAAIHQAIAGATRAPEPPPAPGPAAPAGKAGPSAGEGELGPIRRIVVDAGHGGHDPGAIGPTRVRE
KDVTLAIARRLARKLEAEGFQVVLTRRDDRFLALEERTALANTARGDLFVSVHANAHPRRVRAGVETYFLNVADDRYAAR
LAARENGLDAEDAPSEVARILSDLDAKASADSSRRLAQLVQREVCAGVRSRVGDVKDLGVKSALFYVLLGARMPAVLVET
GFISNRAEEQRLGSARYQDEVASGITRAVAQFARGDARVAAAR

Specific function: Cell-wall hydrolase involved in septum cleavage during cell division [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

Organism=Escherichia coli, GI87082163, Length=399, Percent_Identity=32.0802005012531, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790611, Length=247, Percent_Identity=33.1983805668016, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1788776, Length=241, Percent_Identity=32.7800829875519, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021731
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF11741 AMIN [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 64334; Mature: 64334

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAAVLLTVLMLAAPVEAAPAARYRGRTPAAAKHDAPRRTAARARPAPAPKKPAARAKV
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
SRLVDAKAAMSALMRDRNRRRYRHNWEKAIRGLEQAARGKDAPAALLEASRARYALYRWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEH
AVEADRDEALRLAARATRLGSRDAPALAAAIRREAGDDRPARAAAPPRAAPKRAPTPAPA
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
APAAPEPEPADADEEPAPEPALDAALADLRGEPARPMPLGESGGEGTATVSEVRAWSSGD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
YTRVAIYLSHWVGWHKLELAPEGDRPRRLALDLRPAHLDGKAVERAVAGDQVDRVRAAQN
CEEEEEEEHHHCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCC
GPDTVRVVLDLPGDDKVQLFTLDDPPRLIVDVGTHAAIHQAIAGATRAPEPPPAPGPAAP
CCCEEEEEEECCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCC
AGKAGPSAGEGELGPIRRIVVDAGHGGHDPGAIGPTRVREKDVTLAIARRLARKLEAEGF
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
QVVLTRRDDRFLALEERTALANTARGDLFVSVHANAHPRRVRAGVETYFLNVADDRYAAR
EEEEEECCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCHHHHHCHHHEEEECCCCHHHHH
LAARENGLDAEDAPSEVARILSDLDAKASADSSRRLAQLVQREVCAGVRSRVGDVKDLGV
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KSALFYVLLGARMPAVLVETGFISNRAEEQRLGSARYQDEVASGITRAVAQFARGDARVA
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
AAR
CCC
>Mature Secondary Structure
MRRAAVLLTVLMLAAPVEAAPAARYRGRTPAAAKHDAPRRTAARARPAPAPKKPAARAKV
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
SRLVDAKAAMSALMRDRNRRRYRHNWEKAIRGLEQAARGKDAPAALLEASRARYALYRWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEH
AVEADRDEALRLAARATRLGSRDAPALAAAIRREAGDDRPARAAAPPRAAPKRAPTPAPA
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
APAAPEPEPADADEEPAPEPALDAALADLRGEPARPMPLGESGGEGTATVSEVRAWSSGD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
YTRVAIYLSHWVGWHKLELAPEGDRPRRLALDLRPAHLDGKAVERAVAGDQVDRVRAAQN
CEEEEEEEHHHCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCC
GPDTVRVVLDLPGDDKVQLFTLDDPPRLIVDVGTHAAIHQAIAGATRAPEPPPAPGPAAP
CCCEEEEEEECCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCC
AGKAGPSAGEGELGPIRRIVVDAGHGGHDPGAIGPTRVREKDVTLAIARRLARKLEAEGF
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
QVVLTRRDDRFLALEERTALANTARGDLFVSVHANAHPRRVRAGVETYFLNVADDRYAAR
EEEEEECCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCHHHHHCHHHEEEECCCCHHHHH
LAARENGLDAEDAPSEVARILSDLDAKASADSSRRLAQLVQREVCAGVRSRVGDVKDLGV
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KSALFYVLLGARMPAVLVETGFISNRAEEQRLGSARYQDEVASGITRAVAQFARGDARVA
HHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
AAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]