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The map label for this gene is clcR [H]

Identifier: 220917290

GI number: 220917290

Start: 2428717

End: 2428962

Strand: Direct

Name: clcR [H]

Synonym: A2cp1_2189

Alternate gene names: 220917290

Gene position: 2428717-2428962 (Clockwise)

Preceding gene: 220917284

Following gene: 220917291

Centisome position: 48.29

GC content: 74.39

Gene sequence:

>246_bases
GTGGCCGTCGCCGAGGAGGGCCACGTCGGCCGCGCCGCCCGGAAGCTGCACCTCACGCAGCCGCCCCTGTCGCGGCACAT
CCTCGCGCTCGAGGACGAGCTCGGAACGCGCCTGTTCGAGCGGACGCCGCGCGGGATGATGCTCCTGCCCGCCGGTGAGG
TGTTCCTCTCGCACGCACGGCGGATCCTCGCGGAGGTGGACGTCGCCATCGCGCGGACGAAGGGGGCTGGGGAGGGCGAG
GCGTGA

Upstream 100 bases:

>100_bases
CGGCCCGTGCTTCCGCCGAGGGCCGTGGTCCTCCGGGACCTGACACGCACGCCGGGCTTCGGATAGGTTGCGCCCGTGAG
CCTCACGTATCCAGTCCTTC

Downstream 100 bases:

>100_bases
AGGCCGCGGTAGGCACCGGCAGCGTACGGGCCATGGCGACACGGTGGACGGCGGCGCGGCGAGCGCCAGCCGCGCCGCGA
ACGCGCACATCGTGGCGCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ClcABD operon transcriptional activator [H]

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMMLLPAGEVFLSHARRILAEVDVAIARTKGAGEGE
A

Sequences:

>Translated_81_residues
MAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMMLLPAGEVFLSHARRILAEVDVAIARTKGAGEGE
A
>Mature_80_residues
AVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMMLLPAGEVFLSHARRILAEVDVAIARTKGAGEGEA

Specific function: Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the clcABD chlorocatechol oxidative operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=81, Percent_Identity=51.8518518518518, Blast_Score=79, Evalue=4e-17,
Organism=Escherichia coli, GI2367136, Length=81, Percent_Identity=48.1481481481481, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI87081904, Length=69, Percent_Identity=47.8260869565217, Blast_Score=62, Evalue=8e-12,
Organism=Escherichia coli, GI157672245, Length=66, Percent_Identity=48.4848484848485, Blast_Score=59, Evalue=5e-11,
Organism=Escherichia coli, GI1790399, Length=78, Percent_Identity=43.5897435897436, Blast_Score=58, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 8793; Mature: 8662

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMMLLPAGEVFLSHAR
CCCCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
RILAEVDVAIARTKGAGEGEA
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMMLLPAGEVFLSHAR
CCCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
RILAEVDVAIARTKGAGEGEA
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8419291 [H]