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The map label for this gene is atoS [H]

Identifier: 220917160

GI number: 220917160

Start: 2295732

End: 2297975

Strand: Reverse

Name: atoS [H]

Synonym: A2cp1_2057

Alternate gene names: 220917160

Gene position: 2297975-2295732 (Counterclockwise)

Preceding gene: 220917167

Following gene: 220917159

Centisome position: 45.69

GC content: 72.64

Gene sequence:

>2244_bases
GTGGACATCCGCACCCAGGCCACCCTGCTCGCCGCGATCGTGACGCTCGCCCTCGCGGCGGCGGCGCTGCTCCGCGACAA
CCGCTCCCGCGTCTTCACGCTGTTCGCGCTGTTCTCGGCCGACCTGTTCCTGTTCTCGCTGGCGCTCTTCTTCCTGCGCT
GGAAGCAGTCGTTCGGGACGGTCTGGTGGGAGCGGCTGGCGGTCGGGACCGGGGCGCTCATCCCGGCCGCGGCGCTCGCC
TTCTTCCTCGAGTTCCTCGGGGTGGCGCGCCGGCCCGCCCGGCGCGCGCGGAACGCGATGCTGGCCGGCTCGCTGACCGG
CCTGGTGGTGGCGATCACGCCGCTCGTCCACGTGAAGCCCGCCAAGCTCCTGGTCGGCGCCTACGTGCTGGGCGGCCTCG
CGGCGGTGCTCTCCACCCTGTGGGGCAAGCGGCACGGCTCGCAGACCCGGGTCGAGCGCGCGCGCCTCCAGTACCTGTTC
GTCGGCGCGCTGGTGGCGGTGGTGCTCTCGACGCTCGACATGCTGCCGCTGTTCGGCGTGCCCTATCCGCCGGAGGGGCT
CGGGTCGATCGTCCTCACCGTCTTCATGTTCTTCCTGTCGCAGACGCTGCAGCGCCACCGGCTGCTCGACCTGCACGAGT
TCCTCGGGAAGATCGTGGTGGTCACCGCCCTCGGCCTGGTGCTGGTGGCGATCTACGGCGGCCTGGTGTCGTGGGTGGGC
GACCGGCCGGAGCTCTTCTACTTCAACACGGTGGTGGCCTCGTTCGTGATCCTCTCGCTGTTCGACCCGATGCGCGACAA
GGTCGAGGAGTGGGTGGTCGCGACGCTGTTCCACGAGCGCTACGAGCTGGTGCGGCGCCTCGAGGACCTGCGCGATCGGA
CCGGCAAGGTGATCGAGCCCGCCGGGCTCGCGGCGGTGGTGCTGGACGGGCTGGTGGAGACGCGCCGGGTCACCCACTGC
TCGCTGTGGCTGCTCGCCGACGACCGCCCCGGCTACCGGCTGCTCGACTACCGCGGCCCGCCGCCGGCGCCGTTTTTGGA
GCCGGCCACCGCGCGGGCGCTGCTCGGCGCCTCGTCCTCGGGCCAGAAGGCGATCCTGGCGGAGAACATCGACCGGCGCG
TGTCGGAGCTGCGGGCCCTGCTCCCCACCGGCCCGGGCGACCACGTCAGCCGCCGCGGCGCGCCGGCCGCCATCGCCGAG
GAGCTGAAGCGGCTCGGCGACGCGCGCGCGGTCATGGGCACCATGCGCGCCGGCATCGCCATGCCGCTGCTCGCCGGCGA
CCGGGTGGTCGGGTTCCTGGCCTGCTGGGACGAGCGGGTGCAGGAGGCGTTCGCCTCCGACGAGATCGCGGCGCTCATCG
AGGTGGCGGATCGCTGCGCGCTGGTGATCGAGAACTCGAAGCTGTACCAGCAGATGAAGGAGCGCGACCGCCTCGCCGCG
CTGGGCGAGATGTCCGCCGGCCTGGCGCACGAGATCCGCAACCCGCTCGCCGCCATCAAGGCCGCCATCCAGTACCTCGA
CCCGCGCAAGGTCCCGGAGGACGACCGCGAGTTCTTCGAGATCGTGGTCGAGGAGGTGAACCGCCTGAACGGCGTGGTCA
CCCAGTTCCTCGACTACTCGCGGCCGCTGAAGCCCTCGCTCGCGCCCACGCAGGTGAACGAGGTGCTGGAGAAGACGTTC
AAGCTCCTGCAGGCCGAGGTGCCGGAGTCGGTCCGGCTGGAGCTGGAGCTGGCCGAGTGGCTGCCGCGCGTCCAGGCCGA
CGCGGAGCAGCTGAAGCAGGTGTTCCTCAACCTGGCGCTGAACGCGTTCCAGGCCATGCCGCGCGGCGGACGCCTCACCG
TCTCGACGAAGCTCGCCCGCGACGAGCTGGCGTTCTGGCGCGAGGGGGCGCGGCGCGCCGACGTGGTGGAGATCCGCTTC
CGCGACACCGGCCCGGGCATCCCGGACGACGCGCGGGAGTCGATCTTCGTGCCGTTCTACACCACCAAGGAGAAGGGCAC
CGGCCTCGGCCTCGCCATCTGCCAGCGCATCGTGAAGGCGCAGCAGGGGACGATCGTGGTGCGCTCGGCCCCGGGCGAGG
GCGCCGAGTTCCTCATCGCGCTGCCCGGCCTCCACGAGGAGCGCCCGGCCGAGGCGCCGCGCCCGCCGCTCGACGAGGAG
GAGAAGGCCCGCGCCCGGGAGCGGCGCCGGGCCCGGGCCGAGGCGCGCCTCCGCGGCCGCCGGCGCCGGAAGAAGCACGC
CTGA

Upstream 100 bases:

>100_bases
GCGCACCGGGAGGAACGGCCGGGGCCGCCGGCGGATTCCCTCCCCGGCCGGCGTGCGCCCGTGCGGTGCGCAGCGCCGAA
AAGGGTTAGGATCCCGGGGC

Downstream 100 bases:

>100_bases
TGCGTACCCCTGCCCTTCCGTGGTAACGAGGCGCCGTGGCCCACGTCCTCATCGTAGACGACGAGGTGAACATCCGCCGG
GTCCTCGCGGCCATGCTGAA

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MDIRTQATLLAAIVTLALAAAALLRDNRSRVFTLFALFSADLFLFSLALFFLRWKQSFGTVWWERLAVGTGALIPAAALA
FFLEFLGVARRPARRARNAMLAGSLTGLVVAITPLVHVKPAKLLVGAYVLGGLAAVLSTLWGKRHGSQTRVERARLQYLF
VGALVAVVLSTLDMLPLFGVPYPPEGLGSIVLTVFMFFLSQTLQRHRLLDLHEFLGKIVVVTALGLVLVAIYGGLVSWVG
DRPELFYFNTVVASFVILSLFDPMRDKVEEWVVATLFHERYELVRRLEDLRDRTGKVIEPAGLAAVVLDGLVETRRVTHC
SLWLLADDRPGYRLLDYRGPPPAPFLEPATARALLGASSSGQKAILAENIDRRVSELRALLPTGPGDHVSRRGAPAAIAE
ELKRLGDARAVMGTMRAGIAMPLLAGDRVVGFLACWDERVQEAFASDEIAALIEVADRCALVIENSKLYQQMKERDRLAA
LGEMSAGLAHEIRNPLAAIKAAIQYLDPRKVPEDDREFFEIVVEEVNRLNGVVTQFLDYSRPLKPSLAPTQVNEVLEKTF
KLLQAEVPESVRLELELAEWLPRVQADAEQLKQVFLNLALNAFQAMPRGGRLTVSTKLARDELAFWREGARRADVVEIRF
RDTGPGIPDDARESIFVPFYTTKEKGTGLGLAICQRIVKAQQGTIVVRSAPGEGAEFLIALPGLHEERPAEAPRPPLDEE
EKARARERRRARAEARLRGRRRRKKHA

Sequences:

>Translated_747_residues
MDIRTQATLLAAIVTLALAAAALLRDNRSRVFTLFALFSADLFLFSLALFFLRWKQSFGTVWWERLAVGTGALIPAAALA
FFLEFLGVARRPARRARNAMLAGSLTGLVVAITPLVHVKPAKLLVGAYVLGGLAAVLSTLWGKRHGSQTRVERARLQYLF
VGALVAVVLSTLDMLPLFGVPYPPEGLGSIVLTVFMFFLSQTLQRHRLLDLHEFLGKIVVVTALGLVLVAIYGGLVSWVG
DRPELFYFNTVVASFVILSLFDPMRDKVEEWVVATLFHERYELVRRLEDLRDRTGKVIEPAGLAAVVLDGLVETRRVTHC
SLWLLADDRPGYRLLDYRGPPPAPFLEPATARALLGASSSGQKAILAENIDRRVSELRALLPTGPGDHVSRRGAPAAIAE
ELKRLGDARAVMGTMRAGIAMPLLAGDRVVGFLACWDERVQEAFASDEIAALIEVADRCALVIENSKLYQQMKERDRLAA
LGEMSAGLAHEIRNPLAAIKAAIQYLDPRKVPEDDREFFEIVVEEVNRLNGVVTQFLDYSRPLKPSLAPTQVNEVLEKTF
KLLQAEVPESVRLELELAEWLPRVQADAEQLKQVFLNLALNAFQAMPRGGRLTVSTKLARDELAFWREGARRADVVEIRF
RDTGPGIPDDARESIFVPFYTTKEKGTGLGLAICQRIVKAQQGTIVVRSAPGEGAEFLIALPGLHEERPAEAPRPPLDEE
EKARARERRRARAEARLRGRRRRKKHA
>Mature_747_residues
MDIRTQATLLAAIVTLALAAAALLRDNRSRVFTLFALFSADLFLFSLALFFLRWKQSFGTVWWERLAVGTGALIPAAALA
FFLEFLGVARRPARRARNAMLAGSLTGLVVAITPLVHVKPAKLLVGAYVLGGLAAVLSTLWGKRHGSQTRVERARLQYLF
VGALVAVVLSTLDMLPLFGVPYPPEGLGSIVLTVFMFFLSQTLQRHRLLDLHEFLGKIVVVTALGLVLVAIYGGLVSWVG
DRPELFYFNTVVASFVILSLFDPMRDKVEEWVVATLFHERYELVRRLEDLRDRTGKVIEPAGLAAVVLDGLVETRRVTHC
SLWLLADDRPGYRLLDYRGPPPAPFLEPATARALLGASSSGQKAILAENIDRRVSELRALLPTGPGDHVSRRGAPAAIAE
ELKRLGDARAVMGTMRAGIAMPLLAGDRVVGFLACWDERVQEAFASDEIAALIEVADRCALVIENSKLYQQMKERDRLAA
LGEMSAGLAHEIRNPLAAIKAAIQYLDPRKVPEDDREFFEIVVEEVNRLNGVVTQFLDYSRPLKPSLAPTQVNEVLEKTF
KLLQAEVPESVRLELELAEWLPRVQADAEQLKQVFLNLALNAFQAMPRGGRLTVSTKLARDELAFWREGARRADVVEIRF
RDTGPGIPDDARESIFVPFYTTKEKGTGLGLAICQRIVKAQQGTIVVRSAPGEGAEFLIALPGLHEERPAEAPRPPLDEE
EKARARERRRARAEARLRGRRRRKKHA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=291, Percent_Identity=35.3951890034364, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=35.8649789029536, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=33.4710743801653, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=277, Percent_Identity=25.9927797833935, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788713, Length=240, Percent_Identity=25.8333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=25.4385964912281, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=26.2135922330097, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=25.2136752136752, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=25.8373205741627, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82772; Mature: 82772

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]