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The map label for this gene is aroF [H]

Identifier: 220916952

GI number: 220916952

Start: 2067537

End: 2068607

Strand: Reverse

Name: aroF [H]

Synonym: A2cp1_1848

Alternate gene names: 220916952

Gene position: 2068607-2067537 (Counterclockwise)

Preceding gene: 220916953

Following gene: 220916950

Centisome position: 41.13

GC content: 71.15

Gene sequence:

>1071_bases
GTGCAGAAGACCGAGGACCTGAACATCGCCGCGTTCGACCTCATGCCGTCGCCGGACGAGGTCAAGGCGCGCATCCCCAT
CACCGAGGAGGCCGTCCGCACCGTGGTGGAGGGCCGCCGCGCCATCGAGGCCATCCTCGACGGCCGCGACCCGCGCATGT
TCGGCGTCATCGGCCCCTGCTCCATCCACGACGCCGCCGCCGGGCTCGACTACGCGCGCCGCCTGCGCCTCCTCGCCGAG
GAGGTGAAGGACACGCTGGTGCTGGTGATGCGCGTGTACTTCGAGAAGCCGCGCACGTCCGTGGGCTGGAAGGGCTTCAT
CAACGATCCGTACATGGACGACTCGTTCCGGGTGGACGAGGGCATGGAGCGGGCGCGCCGCTTCCTGCTCCAGGTGAACG
AGCTCGGCCTGCCCGCCGGCACCGAGGCGCTCGACCCGCACGCGCCGCAGTACTACGGCGACCTCGTCTCCTGGACCGCC
ATCGGCGCCCGGACCTCCGAGTCGCAGACGCACCGCGAGATGTCGTCGGGCCTCTCCACCCCGGTCGGCTTCAAGAACGG
CACCGACGGCGACGTGGACGCGGCGGTGAACGCCATCCTGTCGGCGGGGCGGCCGCACAGCTTCCTGGGCGTGAACGGCC
AGGGCCGGTCGGCCATCATCCGCACCCGCGGCAACCGCTACGGCCACCTGGTGCTGCGCGGCGGCGGCGGCCGGCCCAAC
TTCGACACCGTCTCCATCTCGCTCGCCGAGCAGGCGCTCACGCGCGCCAAGCTCCCGCTCAACCTGGTGGTGGACTGCTC
CCACGCGAACTCGTGGAAGAAGCCCGACCTGCAGCCGCTCGTGCTCCGCGACGTGGTGCACCAGGTGCGCGAGGGCAACC
GCTCGGTGGTCGGCTTCATGGTCGAGAGCTTCATCGAGGCGGGCAGCCAGCCCATCCCCGAAGACCTCTCGAAGCTCCGC
TACGGCTGCTCGGTCACCGACGCCTGCGTGGGCTGGGACACCACCGTGGAGATGGTGCGCCAGGCCCGCGAGGTGCTGAA
GGACGTGCTGCCGCGGCGCGACCGCGGGTAG

Upstream 100 bases:

>100_bases
GGCCGGCGGTTTCCTGCTGGGAATCGCCCCTGCGCGGGGTGGAACGGACGCGCCGATCGGGTGTATTTTCGCTCCCCTTC
CCCCGCGCCGGAGCGAGCCC

Downstream 100 bases:

>100_bases
CAGCCGGGCCGCTCGCCCCTCGACGGGCTCGGGGCGAGCGGAGTGATCCCCGCTCATCCCGAGCGTAGCGCGGCGAATGC
CGCGCGAAGTCGAGGGACGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQKTEDLNIAAFDLMPSPDEVKARIPITEEAVRTVVEGRRAIEAILDGRDPRMFGVIGPCSIHDAAAGLDYARRLRLLAE
EVKDTLVLVMRVYFEKPRTSVGWKGFINDPYMDDSFRVDEGMERARRFLLQVNELGLPAGTEALDPHAPQYYGDLVSWTA
IGARTSESQTHREMSSGLSTPVGFKNGTDGDVDAAVNAILSAGRPHSFLGVNGQGRSAIIRTRGNRYGHLVLRGGGGRPN
FDTVSISLAEQALTRAKLPLNLVVDCSHANSWKKPDLQPLVLRDVVHQVREGNRSVVGFMVESFIEAGSQPIPEDLSKLR
YGCSVTDACVGWDTTVEMVRQAREVLKDVLPRRDRG

Sequences:

>Translated_356_residues
MQKTEDLNIAAFDLMPSPDEVKARIPITEEAVRTVVEGRRAIEAILDGRDPRMFGVIGPCSIHDAAAGLDYARRLRLLAE
EVKDTLVLVMRVYFEKPRTSVGWKGFINDPYMDDSFRVDEGMERARRFLLQVNELGLPAGTEALDPHAPQYYGDLVSWTA
IGARTSESQTHREMSSGLSTPVGFKNGTDGDVDAAVNAILSAGRPHSFLGVNGQGRSAIIRTRGNRYGHLVLRGGGGRPN
FDTVSISLAEQALTRAKLPLNLVVDCSHANSWKKPDLQPLVLRDVVHQVREGNRSVVGFMVESFIEAGSQPIPEDLSKLR
YGCSVTDACVGWDTTVEMVRQAREVLKDVLPRRDRG
>Mature_356_residues
MQKTEDLNIAAFDLMPSPDEVKARIPITEEAVRTVVEGRRAIEAILDGRDPRMFGVIGPCSIHDAAAGLDYARRLRLLAE
EVKDTLVLVMRVYFEKPRTSVGWKGFINDPYMDDSFRVDEGMERARRFLLQVNELGLPAGTEALDPHAPQYYGDLVSWTA
IGARTSESQTHREMSSGLSTPVGFKNGTDGDVDAAVNAILSAGRPHSFLGVNGQGRSAIIRTRGNRYGHLVLRGGGGRPN
FDTVSISLAEQALTRAKLPLNLVVDCSHANSWKKPDLQPLVLRDVVHQVREGNRSVVGFMVESFIEAGSQPIPEDLSKLR
YGCSVTDACVGWDTTVEMVRQAREVLKDVLPRRDRG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=355, Percent_Identity=49.8591549295775, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=49.5652173913044, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI1787996, Length=341, Percent_Identity=47.5073313782991, Blast_Score=323, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6319726, Length=354, Percent_Identity=45.4802259887006, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6320240, Length=359, Percent_Identity=42.8969359331476, Blast_Score=304, Evalue=2e-83,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39223; Mature: 39223

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTEDLNIAAFDLMPSPDEVKARIPITEEAVRTVVEGRRAIEAILDGRDPRMFGVIGPC
CCCCCCCCEEEEECCCCCHHCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDAAAGLDYARRLRLLAEEVKDTLVLVMRVYFEKPRTSVGWKGFINDPYMDDSFRVDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GMERARRFLLQVNELGLPAGTEALDPHAPQYYGDLVSWTAIGARTSESQTHREMSSGLST
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGDVDAAVNAILSAGRPHSFLGVNGQGRSAIIRTRGNRYGHLVLRGGGGRPN
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEECCCCCCC
FDTVSISLAEQALTRAKLPLNLVVDCSHANSWKKPDLQPLVLRDVVHQVREGNRSVVGFM
CCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VESFIEAGSQPIPEDLSKLRYGCSVTDACVGWDTTVEMVRQAREVLKDVLPRRDRG
HHHHHHCCCCCCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKTEDLNIAAFDLMPSPDEVKARIPITEEAVRTVVEGRRAIEAILDGRDPRMFGVIGPC
CCCCCCCCEEEEECCCCCHHCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDAAAGLDYARRLRLLAEEVKDTLVLVMRVYFEKPRTSVGWKGFINDPYMDDSFRVDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GMERARRFLLQVNELGLPAGTEALDPHAPQYYGDLVSWTAIGARTSESQTHREMSSGLST
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGDVDAAVNAILSAGRPHSFLGVNGQGRSAIIRTRGNRYGHLVLRGGGGRPN
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEECCCCCCC
FDTVSISLAEQALTRAKLPLNLVVDCSHANSWKKPDLQPLVLRDVVHQVREGNRSVVGFM
CCEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VESFIEAGSQPIPEDLSKLRYGCSVTDACVGWDTTVEMVRQAREVLKDVLPRRDRG
HHHHHHCCCCCCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]