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The map label for this gene is yrpG [H]

Identifier: 220916941

GI number: 220916941

Start: 2056082

End: 2057074

Strand: Reverse

Name: yrpG [H]

Synonym: A2cp1_1837

Alternate gene names: 220916941

Gene position: 2057074-2056082 (Counterclockwise)

Preceding gene: 220916943

Following gene: 220916935

Centisome position: 40.9

GC content: 74.02

Gene sequence:

>993_bases
ATGGACACCACGCGACTGGGAAGGACCGGGCTCGAGGTCAGCCGGCTGTGCCTCGGCACCATGAACTTCGGGCCGGAGAC
GCCGGAGGACGAGGCGTTCCGGATCATGGACCGCGCGCTCGACGCGGGCGTGTTCTTCTTCGACACCGCCAACGTCTACG
GCCAGAAGGCGAGCGAGTGGGGCAAGCTCCCGCGCGAGGGGCGCACCGAGCAGATCGTGGGGCGCTGGCTGGCGCAGGGC
GGCGGGCGGCGCGAGCGCATCGTGCTCGCGACCAAGGTGTACGGGCCGATGTGGGAGGGGCCGAACGGCCGCGGGCTCTC
CGCGTACCACATCCGCCGCGCCTGCGAGGACAGCCTGCGCCGGCTCGGCACCGACCACGTGGACCTGTACCAGATGCACC
ACGTGGACCGCGCCACGCCGTGGGACGAGCTCTGGGAGGCGATGGACCGGCTGGTGCGCGACGGCAAGGTGCTCTACGTC
GGCAGCAGCAACTTCGCCGGCTGGCACGTGGCGCAGGCCTGCGAGGCCGCCGCACGGCGGAACCTCCTCGGCCTCGTCTC
CGAGCAGAGCCTCTACAACCTCGTCTCCCGCACCATCGAGCTGGAGGTGGTCCCGGCCTGCCGCGCCTATGGCGTCGGCA
TCCTGCCCTGGAGCCCGCTCGCGGGCGGCCTCCTCGGCGGCGCGCTCGCGAAGGCCGCCACCGGCCGGCGCGCCGGCGAG
CGGGTGCAGAAGAAGATCGAGCAGCACCGCCCGCAGCTCGAGCGCTGGGAGAAGCTCTGCGCCGAGATGGGCCAGCGGCC
CGCGGACGTGGCGCTGGCGTGGGTGCTGGGGCGGCCCGGCGTCACCGCGCCCATCGTCGGGCCGCGCACCGTGGCCCAGC
TCGACGAGGCCATCGCCGCGACCGAGCTGACGCTCGACGCGGCCGCTGTGCAGGCCATCGACGCGATCTGGCCGGGCCCC
GGCGGCGAGGCGCCGGAGGCGTACGCCTGGTGA

Upstream 100 bases:

>100_bases
GCGCCCGCCGGGCCGGGCGCCCGGGCCGGGCCGTGCGACACGGTGGCGCAGCTTCGGCGCAGCTTGCGCGGCCGCGCCGG
AGGCGCCATCACCTCCACCC

Downstream 100 bases:

>100_bases
GCGTCCGAGTTCCGCCCTTCGACTACGACCCTTCGACTCCGGCGAGCCTTGCGGCTCGCCTACGCTCAGGGTGAGCGGCG
CGGCTGAAGGCCGCGCGGAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDTTRLGRTGLEVSRLCLGTMNFGPETPEDEAFRIMDRALDAGVFFFDTANVYGQKASEWGKLPREGRTEQIVGRWLAQG
GGRRERIVLATKVYGPMWEGPNGRGLSAYHIRRACEDSLRRLGTDHVDLYQMHHVDRATPWDELWEAMDRLVRDGKVLYV
GSSNFAGWHVAQACEAAARRNLLGLVSEQSLYNLVSRTIELEVVPACRAYGVGILPWSPLAGGLLGGALAKAATGRRAGE
RVQKKIEQHRPQLERWEKLCAEMGQRPADVALAWVLGRPGVTAPIVGPRTVAQLDEAIAATELTLDAAAVQAIDAIWPGP
GGEAPEAYAW

Sequences:

>Translated_330_residues
MDTTRLGRTGLEVSRLCLGTMNFGPETPEDEAFRIMDRALDAGVFFFDTANVYGQKASEWGKLPREGRTEQIVGRWLAQG
GGRRERIVLATKVYGPMWEGPNGRGLSAYHIRRACEDSLRRLGTDHVDLYQMHHVDRATPWDELWEAMDRLVRDGKVLYV
GSSNFAGWHVAQACEAAARRNLLGLVSEQSLYNLVSRTIELEVVPACRAYGVGILPWSPLAGGLLGGALAKAATGRRAGE
RVQKKIEQHRPQLERWEKLCAEMGQRPADVALAWVLGRPGVTAPIVGPRTVAQLDEAIAATELTLDAAAVQAIDAIWPGP
GGEAPEAYAW
>Mature_330_residues
MDTTRLGRTGLEVSRLCLGTMNFGPETPEDEAFRIMDRALDAGVFFFDTANVYGQKASEWGKLPREGRTEQIVGRWLAQG
GGRRERIVLATKVYGPMWEGPNGRGLSAYHIRRACEDSLRRLGTDHVDLYQMHHVDRATPWDELWEAMDRLVRDGKVLYV
GSSNFAGWHVAQACEAAARRNLLGLVSEQSLYNLVSRTIELEVVPACRAYGVGILPWSPLAGGLLGGALAKAATGRRAGE
RVQKKIEQHRPQLERWEKLCAEMGQRPADVALAWVLGRPGVTAPIVGPRTVAQLDEAIAATELTLDAAAVQAIDAIWPGP
GGEAPEAYAW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=339, Percent_Identity=30.6784660766962, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI27436962, Length=339, Percent_Identity=30.6784660766962, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI27436966, Length=339, Percent_Identity=30.6784660766962, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI27436969, Length=332, Percent_Identity=28.9156626506024, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=29.0519877675841, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI27436971, Length=339, Percent_Identity=29.2035398230088, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI41327764, Length=333, Percent_Identity=30.3303303303303, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41152114, Length=333, Percent_Identity=28.8288288288288, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI223718702, Length=333, Percent_Identity=27.027027027027, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=39.039039039039, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1789199, Length=361, Percent_Identity=31.0249307479224, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=30.2180685358255, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788070, Length=336, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788081, Length=292, Percent_Identity=28.7671232876712, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=31.9648093841642, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=27.3015873015873, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=27.4052478134111, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=345, Percent_Identity=25.5072463768116, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=249, Percent_Identity=27.710843373494, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324694, Length=248, Percent_Identity=25, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=25.9938837920489, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45549126, Length=328, Percent_Identity=25.9146341463415, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24646155, Length=323, Percent_Identity=26.625386996904, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646159, Length=263, Percent_Identity=28.1368821292776, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644950, Length=305, Percent_Identity=25.2459016393443, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36208; Mature: 36208

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTRLGRTGLEVSRLCLGTMNFGPETPEDEAFRIMDRALDAGVFFFDTANVYGQKASEW
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHCCCHHHH
GKLPREGRTEQIVGRWLAQGGGRRERIVLATKVYGPMWEGPNGRGLSAYHIRRACEDSLR
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RLGTDHVDLYQMHHVDRATPWDELWEAMDRLVRDGKVLYVGSSNFAGWHVAQACEAAARR
HHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
NLLGLVSEQSLYNLVSRTIELEVVPACRAYGVGILPWSPLAGGLLGGALAKAATGRRAGE
HHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHH
RVQKKIEQHRPQLERWEKLCAEMGQRPADVALAWVLGRPGVTAPIVGPRTVAQLDEAIAA
HHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHH
TELTLDAAAVQAIDAIWPGPGGEAPEAYAW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTTRLGRTGLEVSRLCLGTMNFGPETPEDEAFRIMDRALDAGVFFFDTANVYGQKASEW
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHCCCHHHH
GKLPREGRTEQIVGRWLAQGGGRRERIVLATKVYGPMWEGPNGRGLSAYHIRRACEDSLR
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RLGTDHVDLYQMHHVDRATPWDELWEAMDRLVRDGKVLYVGSSNFAGWHVAQACEAAARR
HHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
NLLGLVSEQSLYNLVSRTIELEVVPACRAYGVGILPWSPLAGGLLGGALAKAATGRRAGE
HHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHH
RVQKKIEQHRPQLERWEKLCAEMGQRPADVALAWVLGRPGVTAPIVGPRTVAQLDEAIAA
HHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHH
TELTLDAAAVQAIDAIWPGPGGEAPEAYAW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]