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The map label for this gene is ccdA [H]

Identifier: 220916915

GI number: 220916915

Start: 2025790

End: 2026986

Strand: Reverse

Name: ccdA [H]

Synonym: A2cp1_1811

Alternate gene names: 220916915

Gene position: 2026986-2025790 (Counterclockwise)

Preceding gene: 220916921

Following gene: 220916914

Centisome position: 40.3

GC content: 80.2

Gene sequence:

>1197_bases
ATGGGCTTCGATCTGCCCGGCCTGTTCGCCGCCGGGATCCTCACCTTCGCCTCCCCCTGCGTCCTGCCGCTGGTGCCGGT
CTACCTGTCGCTGCTCGGCGGCGCGTCGGTGGAGGCGCTCCGCCGGGGCGAGCGGCCGCGCGGGCTGGTCCCATCGGCGA
TCGCGTTCTCGCTCGGCCTCGCGGCGGTGTTCGTGGCGCTCGGCGCCGGGGCGAGCGCGGCGGGCGAGGCGCTCTCGGCG
CACCGGGACGCGCTGCTGGCGGTGTCCGGCGCGCTGGTCGTCGCGCTCGGCCTGAAGGTGCTCGGCGTGCTCCGGCTGCC
CGCGCTCGACGTGGAGCGGCGGCCGTGGCTGGCGCGCGTGCGGCCCGGCGGCTCGCTCGCGGCGTCGTTCGCGTTCGGCG
GGGCGTTCGCGCTCGGCTGGACCCCCTGCGTCGGCCCGGTCCTCGGCTCGGTGCTCACCTGGACCGCGTCCGCCGGCGCG
AGCCCGGCCCGCGGCGCGCTCTACCTCGGCACGTACGCGGCCGGCCTGGTGACCCCGCTCGTCCTCGCGGCCGCCTTCGC
GGGGCGCGCGCTCGCCTGGCTCGACCGGCTGAAGCGGCAGCTGCCCCGGCTCGAGAAGGCGACCGGGCTGCTGCTGGTGG
GCGCCGGGATCCTGCTCGCCACCGATCGGCTCATGGTGCTGATGCCGCGGGCGGGCGGCGCCGCGGCAGAGGAGGTCGCG
GCGGGCGCTCCGGCGGTCCCCTCGACCCCGTCCGTCGCGTCGGCCCGGCCGGCCGGGGCCGACGCGCCGGCGGTCTGCAC
CGACGCGTCCTCGGCCGCCTGCGCGGTGGCGGTGCCCGACGCGCCCGGCGCGGCGCCCGCGGCCATTCCGCCGCGGCACG
GCCCGGCGCTGGTCGAGATCGTGAGCCGGAGCTGCCCGGTCTGCCGGCGGATGGAGCCGGTGGTGGCCGCCGCGGAGCAC
GGCTGCCCGGGCGCGCGGGTGGAGCGGCACACGGTGGAGGCGCCGGAGGGCGCGGCGCTGGCGCGCGCGCACCGGGTGGT
GGCCGTGCCCACGTTCCTGGCGCTCGACGGCGCCGGCCGCGAGGTGCAGCGGCTGGTGGGCGAGCAGTCTCTCGACGCGC
TGGTGGACGCGCTGCAGCGCCTCTCCGGCCGGCTGTGCCAGGCCGCGCCGGCGGCGCCGCGACCCGCCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCCGGACGTGTCCAGGGGGCGCCGGCCCGCGTCCAGCGGGCGGCCGGGGCTCCCACATCGGCCCCGTGACGCCGGGCCCG
CGCCCGGGGAGAATCCAGAG

Downstream 100 bases:

>100_bases
GCGATCCTCGAGCGCTGGGCGCGGCGCCGCGCGCCGCGGGGGCACGCCCGCCCGCGGCAACCCCGAAGACCCACGCCTGG
CCCCGGTCGCGGGCGCGCCG

Product: cytochrome c biogenesis protein transmembrane protein

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MGFDLPGLFAAGILTFASPCVLPLVPVYLSLLGGASVEALRRGERPRGLVPSAIAFSLGLAAVFVALGAGASAAGEALSA
HRDALLAVSGALVVALGLKVLGVLRLPALDVERRPWLARVRPGGSLAASFAFGGAFALGWTPCVGPVLGSVLTWTASAGA
SPARGALYLGTYAAGLVTPLVLAAAFAGRALAWLDRLKRQLPRLEKATGLLLVGAGILLATDRLMVLMPRAGGAAAEEVA
AGAPAVPSTPSVASARPAGADAPAVCTDASSAACAVAVPDAPGAAPAAIPPRHGPALVEIVSRSCPVCRRMEPVVAAAEH
GCPGARVERHTVEAPEGAALARAHRVVAVPTFLALDGAGREVQRLVGEQSLDALVDALQRLSGRLCQAAPAAPRPAAG

Sequences:

>Translated_398_residues
MGFDLPGLFAAGILTFASPCVLPLVPVYLSLLGGASVEALRRGERPRGLVPSAIAFSLGLAAVFVALGAGASAAGEALSA
HRDALLAVSGALVVALGLKVLGVLRLPALDVERRPWLARVRPGGSLAASFAFGGAFALGWTPCVGPVLGSVLTWTASAGA
SPARGALYLGTYAAGLVTPLVLAAAFAGRALAWLDRLKRQLPRLEKATGLLLVGAGILLATDRLMVLMPRAGGAAAEEVA
AGAPAVPSTPSVASARPAGADAPAVCTDASSAACAVAVPDAPGAAPAAIPPRHGPALVEIVSRSCPVCRRMEPVVAAAEH
GCPGARVERHTVEAPEGAALARAHRVVAVPTFLALDGAGREVQRLVGEQSLDALVDALQRLSGRLCQAAPAAPRPAAG
>Mature_397_residues
GFDLPGLFAAGILTFASPCVLPLVPVYLSLLGGASVEALRRGERPRGLVPSAIAFSLGLAAVFVALGAGASAAGEALSAH
RDALLAVSGALVVALGLKVLGVLRLPALDVERRPWLARVRPGGSLAASFAFGGAFALGWTPCVGPVLGSVLTWTASAGAS
PARGALYLGTYAAGLVTPLVLAAAFAGRALAWLDRLKRQLPRLEKATGLLLVGAGILLATDRLMVLMPRAGGAAAEEVAA
GAPAVPSTPSVASARPAGADAPAVCTDASSAACAVAVPDAPGAAPAAIPPRHGPALVEIVSRSCPVCRRMEPVVAAAEHG
CPGARVERHTVEAPEGAALARAHRVVAVPTFLALDGAGREVQRLVGEQSLDALVDALQRLSGRLCQAAPAAPRPAAG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 39724; Mature: 39593

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFDLPGLFAAGILTFASPCVLPLVPVYLSLLGGASVEALRRGERPRGLVPSAIAFSLGL
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHH
AAVFVALGAGASAAGEALSAHRDALLAVSGALVVALGLKVLGVLRLPALDVERRPWLARV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
RPGGSLAASFAFGGAFALGWTPCVGPVLGSVLTWTASAGASPARGALYLGTYAAGLVTPL
CCCCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
VLAAAFAGRALAWLDRLKRQLPRLEKATGLLLVGAGILLATDRLMVLMPRAGGAAAEEVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCHHHHHCCCEEEEEECCCCCHHHHHH
AGAPAVPSTPSVASARPAGADAPAVCTDASSAACAVAVPDAPGAAPAAIPPRHGPALVEI
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VSRSCPVCRRMEPVVAAAEHGCPGARVERHTVEAPEGAALARAHRVVAVPTFLALDGAGR
HHHCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEHHHEEECCCCH
EVQRLVGEQSLDALVDALQRLSGRLCQAAPAAPRPAAG
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GFDLPGLFAAGILTFASPCVLPLVPVYLSLLGGASVEALRRGERPRGLVPSAIAFSLGL
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHH
AAVFVALGAGASAAGEALSAHRDALLAVSGALVVALGLKVLGVLRLPALDVERRPWLARV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
RPGGSLAASFAFGGAFALGWTPCVGPVLGSVLTWTASAGASPARGALYLGTYAAGLVTPL
CCCCCHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
VLAAAFAGRALAWLDRLKRQLPRLEKATGLLLVGAGILLATDRLMVLMPRAGGAAAEEVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCHHHHHCCCEEEEEECCCCCHHHHHH
AGAPAVPSTPSVASARPAGADAPAVCTDASSAACAVAVPDAPGAAPAAIPPRHGPALVEI
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VSRSCPVCRRMEPVVAAAEHGCPGARVERHTVEAPEGAALARAHRVVAVPTFLALDGAGR
HHHCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEHHHEEECCCCH
EVQRLVGEQSLDALVDALQRLSGRLCQAAPAAPRPAAG
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]