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The map label for this gene is icd [H]

Identifier: 220916825

GI number: 220916825

Start: 1918854

End: 1921085

Strand: Direct

Name: icd [H]

Synonym: A2cp1_1721

Alternate gene names: 220916825

Gene position: 1918854-1921085 (Clockwise)

Preceding gene: 220916824

Following gene: 220916826

Centisome position: 38.15

GC content: 67.83

Gene sequence:

>2232_bases
ATGACGACGAAGACCTCCACGATCATCTGGACCGAAATCGACGAAGCGCCGGCGCTCGCCACCTACTCGCTGCTGCCCAT
CGTCCAGGCCTTCACCAAGGGCACCGGCGTCGACGTCCAGACGCGTGACATCTCGCTCTCCGGCCGCATCATCGCGGCGT
TCCCGGAGAAGCTCACCGAGGCGCAGCGGATCCCGGACTACCTGGCGCAGCTCGGCGAGCTCACCCAGAGCCCCGACGCG
AACATCATCAAGCTCCCGAACATCAGCGCCTCGCTCCCGCAGCTCAAGGACGCGATCAAGGAGCTGCAGGGCAAGGGCTA
CGCGGTCCCGGACTACCCGGAGGCCCCCAAGGACGAGGCCGAGAAGGCCGTCCAGGCGCGCTACGCCAAGGTGCTGGGCA
GCGCGGTGAACCCGGTGCTCCGCGAGGGCAACTCGGACCGCCGCTCGCCGCTCTCGGTGAAGGCGTTCTCGAAGAAGCAC
CCGCACAAGCTGGGCGCGTGGAACCCGGAGTCGAAGGCCCACGTCGCGCACATGACCGCGGACGACTTCTACGGGCACGA
GACCTCCACCACGGTCGCGAAGGCCACCACCTTCCGCATCGAGCACGTGGCGCCGGACGGCGCGGTGACGGTGCTGAAGA
AGGACGCGCCGCTCCTCGACGGCGAGGTCATCGACTCGACCATCATGGACGTCCGCGCGCTCCGGAAGTTCTACGCGGAG
CAGATCGAGGACGCGAAGCGCCAGGGGGTGCTGTTCTCGCTGCACCTCAAGGCCACCATGATGAAGGTCTCCGACCCCGT
CATGTTCGGGCACGCGGTGACGGTGTTCTTCGAGGACGTGTTCGCGAAGCACGCCGAGACGTTCAAGCAGCTCGGCGTGA
ACCCGAACCTCGGCCTGGGCGACCTGTACAAGCGGCTCGAGGGCCTGCCGGCCGCGAAGAAGGCCGAGATCGAGGCCGAC
ATCAAGGCGACCTACGCGAAGCGCCCGGCGCTCGCGATGGTGGACTCGGACAAGGGCATCACCAACCTGCACGCGCCGAA
CGACATCATCATCGACGCGTCCATGCCGGTGGTGGTCCGCGAGTCCGGCAAGATGTGGAACGCCGAGGGCAAGCTGCAGG
ACGCCAAGGCGGTGATCCCGGATCGCTGCTACGCCACGATCTACAAGGAGATCGTCGAGGACTGCCGCAAGCACGGCGCC
TTCGACCCGGCCACCATGGGCAACGTGCCGAACGTCGGCCTGATGGCGCAGAAGGCCGAGGAGTACGGCTCGCACGACAA
GACGTTCATCGCGGGCGCCAAGGGCAAGATCCGGGTGGTGGACGGCGCCGGCGCGACGCTGCTCGAGCAGGCGGTCGAGG
CGGGCGACATCTTCCGCATGTGCCAGGCGAAGGACATCCCGATCCGCGACTGGGTGAAGCTGGCGGTGAACCGCGCCCGC
GCCACCGGCACGCCGGCGGTGTTCTGGCTGGACAAGAACCGCGCCCACGACGCGCAGATGATCGCGAAGGTCCAGAAGTA
CCTGAACGACCACGACACCCGCGGCCTGGAGATCAAGATCCTCGCGCCGGTCGAGGCGATGCGCTACTCGCTGGAGCGGA
TCCGCAAGGGCCAGGACACCATCTCGGTGACCGGCAACGCGCTCCGCGACTACCTCACCGACCTGTTCCCCATCCTCGAG
ATCGGCACCAGCGCGAAGATGCTGTCGATCGTCCCGCTGCTCGCCGGCGGCGGGCTGTTCGAGACGGGCGCCGGCGGCTC
GGCCCCCAAGCACGTCCAGCAGTTCGTGAAGGAGGGCTACCTGCGCTGGGACTCGCTGGGTGAGTTCTCCGCGCTGGGCG
CGTCGCTCGAGCACATCGGCCGCGCCGGCGGCAACGCCAAGGCGGCGGTGCTCGCCGAGACGCTCGACCAGGCCATCGGC
AAGTTCCTCGACAACAACAAGTCCCCGGCCCGCAAGGTCGGCCAGATCGACAACCGCGGCAGCCACTTCTACCTGGCGCT
GTACTGGGCCGAGGCGCTCGCCGCGCAGTCGAAGGACAAGGAGCTGCAGGCCCGCTTCGCGAAGCTCGCGAAGCAGCTGG
CGGACAACGCCGCGAAGATCGACCAGGAGCTGCTCGCGGCCCAGGGCAAGCCGGTGGACATGGGCGGTTACTACCGGCCG
GATCCGGTGAAGACCGGGAAGGCGATGCGTCCCAGCGCGACGCTGAACGCAATCATCGACGCGATGGCGTAA

Upstream 100 bases:

>100_bases
TGAGGAATCGTGGCATGTCGGGCACCTCACTCGGGACGGGGCCGGCGCTGCCGTGGTGGTCGCCGACGACGAGGATCACG
CAAGCCAAGGACGAGGGAAA

Downstream 100 bases:

>100_bases
CTGCAGGAATCCAACCAGTCAGGCGAGGGAGACGAACATGGCCAGGTCCAAGATTGCACTGATCGGCGGTGGGCAGATCG
GCGGCGTGCTGGCGCAGCTC

Product: isocitrate dehydrogenase, NADP-dependent

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MTTKTSTIIWTEIDEAPALATYSLLPIVQAFTKGTGVDVQTRDISLSGRIIAAFPEKLTEAQRIPDYLAQLGELTQSPDA
NIIKLPNISASLPQLKDAIKELQGKGYAVPDYPEAPKDEAEKAVQARYAKVLGSAVNPVLREGNSDRRSPLSVKAFSKKH
PHKLGAWNPESKAHVAHMTADDFYGHETSTTVAKATTFRIEHVAPDGAVTVLKKDAPLLDGEVIDSTIMDVRALRKFYAE
QIEDAKRQGVLFSLHLKATMMKVSDPVMFGHAVTVFFEDVFAKHAETFKQLGVNPNLGLGDLYKRLEGLPAAKKAEIEAD
IKATYAKRPALAMVDSDKGITNLHAPNDIIIDASMPVVVRESGKMWNAEGKLQDAKAVIPDRCYATIYKEIVEDCRKHGA
FDPATMGNVPNVGLMAQKAEEYGSHDKTFIAGAKGKIRVVDGAGATLLEQAVEAGDIFRMCQAKDIPIRDWVKLAVNRAR
ATGTPAVFWLDKNRAHDAQMIAKVQKYLNDHDTRGLEIKILAPVEAMRYSLERIRKGQDTISVTGNALRDYLTDLFPILE
IGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFVKEGYLRWDSLGEFSALGASLEHIGRAGGNAKAAVLAETLDQAIG
KFLDNNKSPARKVGQIDNRGSHFYLALYWAEALAAQSKDKELQARFAKLAKQLADNAAKIDQELLAAQGKPVDMGGYYRP
DPVKTGKAMRPSATLNAIIDAMA

Sequences:

>Translated_743_residues
MTTKTSTIIWTEIDEAPALATYSLLPIVQAFTKGTGVDVQTRDISLSGRIIAAFPEKLTEAQRIPDYLAQLGELTQSPDA
NIIKLPNISASLPQLKDAIKELQGKGYAVPDYPEAPKDEAEKAVQARYAKVLGSAVNPVLREGNSDRRSPLSVKAFSKKH
PHKLGAWNPESKAHVAHMTADDFYGHETSTTVAKATTFRIEHVAPDGAVTVLKKDAPLLDGEVIDSTIMDVRALRKFYAE
QIEDAKRQGVLFSLHLKATMMKVSDPVMFGHAVTVFFEDVFAKHAETFKQLGVNPNLGLGDLYKRLEGLPAAKKAEIEAD
IKATYAKRPALAMVDSDKGITNLHAPNDIIIDASMPVVVRESGKMWNAEGKLQDAKAVIPDRCYATIYKEIVEDCRKHGA
FDPATMGNVPNVGLMAQKAEEYGSHDKTFIAGAKGKIRVVDGAGATLLEQAVEAGDIFRMCQAKDIPIRDWVKLAVNRAR
ATGTPAVFWLDKNRAHDAQMIAKVQKYLNDHDTRGLEIKILAPVEAMRYSLERIRKGQDTISVTGNALRDYLTDLFPILE
IGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFVKEGYLRWDSLGEFSALGASLEHIGRAGGNAKAAVLAETLDQAIG
KFLDNNKSPARKVGQIDNRGSHFYLALYWAEALAAQSKDKELQARFAKLAKQLADNAAKIDQELLAAQGKPVDMGGYYRP
DPVKTGKAMRPSATLNAIIDAMA
>Mature_742_residues
TTKTSTIIWTEIDEAPALATYSLLPIVQAFTKGTGVDVQTRDISLSGRIIAAFPEKLTEAQRIPDYLAQLGELTQSPDAN
IIKLPNISASLPQLKDAIKELQGKGYAVPDYPEAPKDEAEKAVQARYAKVLGSAVNPVLREGNSDRRSPLSVKAFSKKHP
HKLGAWNPESKAHVAHMTADDFYGHETSTTVAKATTFRIEHVAPDGAVTVLKKDAPLLDGEVIDSTIMDVRALRKFYAEQ
IEDAKRQGVLFSLHLKATMMKVSDPVMFGHAVTVFFEDVFAKHAETFKQLGVNPNLGLGDLYKRLEGLPAAKKAEIEADI
KATYAKRPALAMVDSDKGITNLHAPNDIIIDASMPVVVRESGKMWNAEGKLQDAKAVIPDRCYATIYKEIVEDCRKHGAF
DPATMGNVPNVGLMAQKAEEYGSHDKTFIAGAKGKIRVVDGAGATLLEQAVEAGDIFRMCQAKDIPIRDWVKLAVNRARA
TGTPAVFWLDKNRAHDAQMIAKVQKYLNDHDTRGLEIKILAPVEAMRYSLERIRKGQDTISVTGNALRDYLTDLFPILEI
GTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFVKEGYLRWDSLGEFSALGASLEHIGRAGGNAKAAVLAETLDQAIGK
FLDNNKSPARKVGQIDNRGSHFYLALYWAEALAAQSKDKELQARFAKLAKQLADNAAKIDQELLAAQGKPVDMGGYYRPD
PVKTGKAMRPSATLNAIIDAMA

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 80801; Mature: 80670

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKTSTIIWTEIDEAPALATYSLLPIVQAFTKGTGVDVQTRDISLSGRIIAAFPEKLTE
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEECCCHHHHH
AQRIPDYLAQLGELTQSPDANIIKLPNISASLPQLKDAIKELQGKGYAVPDYPEAPKDEA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EKAVQARYAKVLGSAVNPVLREGNSDRRSPLSVKAFSKKHPHKLGAWNPESKAHVAHMTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCEEEEEEH
DDFYGHETSTTVAKATTFRIEHVAPDGAVTVLKKDAPLLDGEVIDSTIMDVRALRKFYAE
HHHCCCCCCCHHHHHEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QIEDAKRQGVLFSLHLKATMMKVSDPVMFGHAVTVFFEDVFAKHAETFKQLGVNPNLGLG
HHHHHHHCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
DLYKRLEGLPAAKKAEIEADIKATYAKRPALAMVDSDKGITNLHAPNDIIIDASMPVVVR
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEC
ESGKMWNAEGKLQDAKAVIPDRCYATIYKEIVEDCRKHGAFDPATMGNVPNVGLMAQKAE
CCCCEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHH
EYGSHDKTFIAGAKGKIRVVDGAGATLLEQAVEAGDIFRMCQAKDIPIRDWVKLAVNRAR
HHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
ATGTPAVFWLDKNRAHDAQMIAKVQKYLNDHDTRGLEIKILAPVEAMRYSLERIRKGQDT
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCE
ISVTGNALRDYLTDLFPILEIGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFVKEGY
EEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSLGEFSALGASLEHIGRAGGNAKAAVLAETLDQAIGKFLDNNKSPARKVGQIDNRG
EECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCC
SHFYLALYWAEALAAQSKDKELQARFAKLAKQLADNAAKIDQELLAAQGKPVDMGGYYRP
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPVKTGKAMRPSATLNAIIDAMA
CCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TTKTSTIIWTEIDEAPALATYSLLPIVQAFTKGTGVDVQTRDISLSGRIIAAFPEKLTE
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEECCCHHHHH
AQRIPDYLAQLGELTQSPDANIIKLPNISASLPQLKDAIKELQGKGYAVPDYPEAPKDEA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EKAVQARYAKVLGSAVNPVLREGNSDRRSPLSVKAFSKKHPHKLGAWNPESKAHVAHMTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCEEEEEEH
DDFYGHETSTTVAKATTFRIEHVAPDGAVTVLKKDAPLLDGEVIDSTIMDVRALRKFYAE
HHHCCCCCCCHHHHHEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QIEDAKRQGVLFSLHLKATMMKVSDPVMFGHAVTVFFEDVFAKHAETFKQLGVNPNLGLG
HHHHHHHCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
DLYKRLEGLPAAKKAEIEADIKATYAKRPALAMVDSDKGITNLHAPNDIIIDASMPVVVR
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEC
ESGKMWNAEGKLQDAKAVIPDRCYATIYKEIVEDCRKHGAFDPATMGNVPNVGLMAQKAE
CCCCEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHH
EYGSHDKTFIAGAKGKIRVVDGAGATLLEQAVEAGDIFRMCQAKDIPIRDWVKLAVNRAR
HHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
ATGTPAVFWLDKNRAHDAQMIAKVQKYLNDHDTRGLEIKILAPVEAMRYSLERIRKGQDT
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCE
ISVTGNALRDYLTDLFPILEIGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFVKEGY
EEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSLGEFSALGASLEHIGRAGGNAKAAVLAETLDQAIGKFLDNNKSPARKVGQIDNRG
EECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCC
SHFYLALYWAEALAAQSKDKELQARFAKLAKQLADNAAKIDQELLAAQGKPVDMGGYYRP
CEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPVKTGKAMRPSATLNAIIDAMA
CCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]