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The map label for this gene is bioC [C]

Identifier: 220916788

GI number: 220916788

Start: 1874628

End: 1875491

Strand: Reverse

Name: bioC [C]

Synonym: A2cp1_1683

Alternate gene names: 220916788

Gene position: 1875491-1874628 (Counterclockwise)

Preceding gene: 220916792

Following gene: 220916787

Centisome position: 37.29

GC content: 77.08

Gene sequence:

>864_bases
ATGAACGGCATCGCTTCCCGCTCCCCCACCCCCATGACCCCGCCCGCCGCGCCGCCCCCGGGCCTCGACCTCGACGCCGT
GAAGGCACGGCAGCAGTCCACCTGGAGCTCGGGGGACTACGCGGTGATCGGCACCACGCTGCAGATCGTCGGCGAGACGC
TCTGCGAGGCGGCCGCGGTCTCGGCCGGCGAGCGCGTCCTCGACGTGGCCTGCGGCAACGGCAACGCCGCGCTCGCGGCG
GCCCGCCGCTTCGCGCGCGTGACCGGGGTCGACTACGTCCCCGCGCTGCTCGAGCGGGCGAGCGCCCGCGCGGCGGCCGA
CGGCCTCGCGGTGGAGCTCCGCGGCGGCGACGCCGAGGCGCTGCCGTTCGACGACGGCGCGTTCGACGTGGTGCTCTCGA
CGTTCGGCGTGATGTTCACGCCCGACCAGGCGCGCGCCGCGGGCGAGCTGCTCCGGGTGTGCCGCCCGGGCGGCCGCATC
GCGCTCGCCTCGTGGACGCCGGACGGCTTCATCGGCAAGGTGTTCCAGGCGGTGGGCCGCCACGTGCCGCCGCCCGCCGG
CCTCCGACCGCCGGCCGCCTGGGGCACCGAGGCGCGCCTCCACGAGCTGTTCGTCCCCGGCGCCCGCGAGATCCGCGCGC
AGCGCCGCGAGTTCGTGTTCCGCTACCGCTCGGCGGCGCACTGGGTGGAGGTGTTCCGCACCTGGTACGGCCCCATCCAC
CGCGCGTTCGCGGCGCTCGCCGCCGAAGCGCGGCCGGCGCTCGAGCGCGACCTGCTCGCGCTGCTCGAGGAGGCCGACAC
CGCCACCGACGGCACGCTCGCGGTGCCGGCCACGTACCTCGAGGCGGTGATCACCCGGGCGTAG

Upstream 100 bases:

>100_bases
GGCAACGAACGCGGCGGGGCGAGCAGGTCCGGACCGGCCCGGGTTTCCTAGATCCCGCCCGGCGTCCACGCCACCTGACC
TGCAGGCAAGGAGACCGCAG

Downstream 100 bases:

>100_bases
CGCGCGCGGGCCGCCGGTGTCCGCGATCCCCACGACGCCGGCCGCCTGACGCCACGCGAGCGCGGAGCCGCGCCGGCGCC
TCGGGGTGGCTCCCGACCCC

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNGIASRSPTPMTPPAAPPPGLDLDAVKARQQSTWSSGDYAVIGTTLQIVGETLCEAAAVSAGERVLDVACGNGNAALAA
ARRFARVTGVDYVPALLERASARAAADGLAVELRGGDAEALPFDDGAFDVVLSTFGVMFTPDQARAAGELLRVCRPGGRI
ALASWTPDGFIGKVFQAVGRHVPPPAGLRPPAAWGTEARLHELFVPGAREIRAQRREFVFRYRSAAHWVEVFRTWYGPIH
RAFAALAAEARPALERDLLALLEEADTATDGTLAVPATYLEAVITRA

Sequences:

>Translated_287_residues
MNGIASRSPTPMTPPAAPPPGLDLDAVKARQQSTWSSGDYAVIGTTLQIVGETLCEAAAVSAGERVLDVACGNGNAALAA
ARRFARVTGVDYVPALLERASARAAADGLAVELRGGDAEALPFDDGAFDVVLSTFGVMFTPDQARAAGELLRVCRPGGRI
ALASWTPDGFIGKVFQAVGRHVPPPAGLRPPAAWGTEARLHELFVPGAREIRAQRREFVFRYRSAAHWVEVFRTWYGPIH
RAFAALAAEARPALERDLLALLEEADTATDGTLAVPATYLEAVITRA
>Mature_287_residues
MNGIASRSPTPMTPPAAPPPGLDLDAVKARQQSTWSSGDYAVIGTTLQIVGETLCEAAAVSAGERVLDVACGNGNAALAA
ARRFARVTGVDYVPALLERASARAAADGLAVELRGGDAEALPFDDGAFDVVLSTFGVMFTPDQARAAGELLRVCRPGGRI
ALASWTPDGFIGKVFQAVGRHVPPPAGLRPPAAWGTEARLHELFVPGAREIRAQRREFVFRYRSAAHWVEVFRTWYGPIH
RAFAALAAEARPALERDLLALLEEADTATDGTLAVPATYLEAVITRA

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv1403c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 30381; Mature: 30381

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIASRSPTPMTPPAAPPPGLDLDAVKARQQSTWSSGDYAVIGTTLQIVGETLCEAAAV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
SAGERVLDVACGNGNAALAAARRFARVTGVDYVPALLERASARAAADGLAVELRGGDAEA
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
LPFDDGAFDVVLSTFGVMFTPDQARAAGELLRVCRPGGRIALASWTPDGFIGKVFQAVGR
CCCCCCHHHHHHHHHCCEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
HVPPPAGLRPPAAWGTEARLHELFVPGAREIRAQRREFVFRYRSAAHWVEVFRTWYGPIH
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFAALAAEARPALERDLLALLEEADTATDGTLAVPATYLEAVITRA
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MNGIASRSPTPMTPPAAPPPGLDLDAVKARQQSTWSSGDYAVIGTTLQIVGETLCEAAAV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
SAGERVLDVACGNGNAALAAARRFARVTGVDYVPALLERASARAAADGLAVELRGGDAEA
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
LPFDDGAFDVVLSTFGVMFTPDQARAAGELLRVCRPGGRIALASWTPDGFIGKVFQAVGR
CCCCCCHHHHHHHHHCCEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
HVPPPAGLRPPAAWGTEARLHELFVPGAREIRAQRREFVFRYRSAAHWVEVFRTWYGPIH
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFAALAAEARPALERDLLALLEEADTATDGTLAVPATYLEAVITRA
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]