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The map label for this gene is ctaD [H]

Identifier: 220916782

GI number: 220916782

Start: 1868556

End: 1870223

Strand: Direct

Name: ctaD [H]

Synonym: A2cp1_1677

Alternate gene names: 220916782

Gene position: 1868556-1870223 (Clockwise)

Preceding gene: 220916781

Following gene: 220916783

Centisome position: 37.15

GC content: 68.17

Gene sequence:

>1668_bases
ATGAGCAGCACCGCGGCAGTGGCCGTGCGCGCGCCGGCGCACGAGACCGGGAGCTACCTCGAGCACGGGCGCGGCGTCCG
CTCCTGGCTCTTCACCCTGGACCACAAGCGCATCGGGATCATGTACCTGGTCGCGATCTCCGCCTGCCTGCTGCTGGGCG
GCGTGTTCGCGCTGGCGCTCCGGATGCACCTCTGGAATCCGCAGGGCGCGCTGGTCTCGAACGACGCCTACAACAAGCTG
TTCACGCTGCACGGCGCGGTGATGATCTTCCTGTTCATCATCCCCGGCATCCCCGCGGCGCTCGGCAACTTCGTGCTGCC
GCTCCAGCTCGGCGCGAAGGACATGGCCTTCCCGCGCGTCAACCTGCTCAGCTTCTGGCTGTTCGTGGCGGGCGCGATCT
TCTTCGTGGTGGTGCTGGTGGTGGGCGGGGTGGACACCGGCTGGACGCTGTACCCGCCCTACAGCCTGGAGAGCGCGCGC
GGCCTCGGGATCCTGCTGGCGCTGTCGGCGGTGGTGCTCACCGGCTTCAGCTCGATCCTCACCGGCGTGAACTTCATCGC
CACCATCCACCGCATGCGGCCGCCGGGGATGGGCTGGTTCGACATGCCGCTGTTCCTGTGGGCGCTCTACGCCACCGGCG
TCATCCAGATCATCTCCACGCCGGTGCTGGGCATCACCGCGGCGATGGGCTTCCTGGAGCGGATCTTCCACCTCGGGCTG
TTCATGCCGGAGTACGGCGGCGATCCCATCCTGTTCCAGCACTTCTTCTGGTTCTACTCGCACCCCGCCGTCTACATCAT
GATCCTGCCGGCCATGGGCGTGGTGTCGGAGGTGGTCTCGGTCTTCAGCCGCAAGCCCATCTTCGGCTACCGCTTCATCG
CGGTGAGCTCGATGGCCATCGCGATCATCGGCTTCCTGGTGTGGGGGCACCACATGTTCGTCTCGGGCCAGTCGCGCTGG
GCGAGCCTGGCCTTCAGCTTCCTCACCATGCTGGTGTCGATCCCGTCGGCCATCAAGACGTTCAACTGGATCGCCACCAT
GTACAAGGGCGCCATCGTCCTGAAGACGCCCATGGTGTACGTGCTCACGTTCTTCGCCATCTTCGGCGTGGGCGGGCTCA
CCGGCCTGTTCCTCGGCCTGCTCGCCACCGACATCCCGCTGCACGACACCTACTTCGTGGTGGCGCACTTCCACTTCGTG
ATGGTCGGCGCGGTGATGATCGCGTTCCTGGCCGGCCTGCACTACTGGTGGCCGAAGATGACCGGCCGCATGTACCACGA
GGGCGTGGGCGTGACGTCTGCGTGGCTGGTGTTCCTCGGCTTCAACCTCACGTTCGTGCCGCAGTTCCTGGCCGGCGTGC
TGGGCATGCCGCGCCGGTATGCCACGTACGCGCCGCAGTTCACCGCGCACAACCGGCTCTCCACCGTGGGCGCGTTCGTG
CTCGCCCTCGGCCTGGCGCTGGCGCTCGCCGGGCTGCTCCACTCGCTGCGGCGCGGCCGCCGCGCGCCGCCCAACCCGTG
GGGCGCGGCGTCGCTGGAGTGGACCGTCGCCTCGCCGCCCACCCACCACAACTTCGACGCAACGCCGCGCGCCCGCGGCC
CGTACGACTACTCGGGGCTGCACGAGGTCTCCGAGGACGCGGGCTGGGTGCGCGAGGAGGGACGCTAG

Upstream 100 bases:

>100_bases
CCATGCCGCTGGAGGAGCGCGAGCTGAAGGCCGTCGCCGCGTACCTCGAGACGCTCGCCGTCGAGGGCGGCGCGCCGGCG
AAGGGCGAGGAGACGAAGCG

Downstream 100 bases:

>100_bases
ATGGACGCGACCGCCCAGCCCGCCGCCGCCCGCCCGGAGCGCGGCCGGTTCCTGGCCGTGCAGTTCGAGGACATGCCCGC
CCAGCTCGCCACCGGCAAGC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSSTAAVAVRAPAHETGSYLEHGRGVRSWLFTLDHKRIGIMYLVAISACLLLGGVFALALRMHLWNPQGALVSNDAYNKL
FTLHGAVMIFLFIIPGIPAALGNFVLPLQLGAKDMAFPRVNLLSFWLFVAGAIFFVVVLVVGGVDTGWTLYPPYSLESAR
GLGILLALSAVVLTGFSSILTGVNFIATIHRMRPPGMGWFDMPLFLWALYATGVIQIISTPVLGITAAMGFLERIFHLGL
FMPEYGGDPILFQHFFWFYSHPAVYIMILPAMGVVSEVVSVFSRKPIFGYRFIAVSSMAIAIIGFLVWGHHMFVSGQSRW
ASLAFSFLTMLVSIPSAIKTFNWIATMYKGAIVLKTPMVYVLTFFAIFGVGGLTGLFLGLLATDIPLHDTYFVVAHFHFV
MVGAVMIAFLAGLHYWWPKMTGRMYHEGVGVTSAWLVFLGFNLTFVPQFLAGVLGMPRRYATYAPQFTAHNRLSTVGAFV
LALGLALALAGLLHSLRRGRRAPPNPWGAASLEWTVASPPTHHNFDATPRARGPYDYSGLHEVSEDAGWVREEGR

Sequences:

>Translated_555_residues
MSSTAAVAVRAPAHETGSYLEHGRGVRSWLFTLDHKRIGIMYLVAISACLLLGGVFALALRMHLWNPQGALVSNDAYNKL
FTLHGAVMIFLFIIPGIPAALGNFVLPLQLGAKDMAFPRVNLLSFWLFVAGAIFFVVVLVVGGVDTGWTLYPPYSLESAR
GLGILLALSAVVLTGFSSILTGVNFIATIHRMRPPGMGWFDMPLFLWALYATGVIQIISTPVLGITAAMGFLERIFHLGL
FMPEYGGDPILFQHFFWFYSHPAVYIMILPAMGVVSEVVSVFSRKPIFGYRFIAVSSMAIAIIGFLVWGHHMFVSGQSRW
ASLAFSFLTMLVSIPSAIKTFNWIATMYKGAIVLKTPMVYVLTFFAIFGVGGLTGLFLGLLATDIPLHDTYFVVAHFHFV
MVGAVMIAFLAGLHYWWPKMTGRMYHEGVGVTSAWLVFLGFNLTFVPQFLAGVLGMPRRYATYAPQFTAHNRLSTVGAFV
LALGLALALAGLLHSLRRGRRAPPNPWGAASLEWTVASPPTHHNFDATPRARGPYDYSGLHEVSEDAGWVREEGR
>Mature_554_residues
SSTAAVAVRAPAHETGSYLEHGRGVRSWLFTLDHKRIGIMYLVAISACLLLGGVFALALRMHLWNPQGALVSNDAYNKLF
TLHGAVMIFLFIIPGIPAALGNFVLPLQLGAKDMAFPRVNLLSFWLFVAGAIFFVVVLVVGGVDTGWTLYPPYSLESARG
LGILLALSAVVLTGFSSILTGVNFIATIHRMRPPGMGWFDMPLFLWALYATGVIQIISTPVLGITAAMGFLERIFHLGLF
MPEYGGDPILFQHFFWFYSHPAVYIMILPAMGVVSEVVSVFSRKPIFGYRFIAVSSMAIAIIGFLVWGHHMFVSGQSRWA
SLAFSFLTMLVSIPSAIKTFNWIATMYKGAIVLKTPMVYVLTFFAIFGVGGLTGLFLGLLATDIPLHDTYFVVAHFHFVM
VGAVMIAFLAGLHYWWPKMTGRMYHEGVGVTSAWLVFLGFNLTFVPQFLAGVLGMPRRYATYAPQFTAHNRLSTVGAFVL
ALGLALALAGLLHSLRRGRRAPPNPWGAASLEWTVASPPTHHNFDATPRARGPYDYSGLHEVSEDAGWVREEGR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=501, Percent_Identity=38.3233532934132, Blast_Score=334, Evalue=1e-91,
Organism=Escherichia coli, GI1786634, Length=544, Percent_Identity=38.0514705882353, Blast_Score=361, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226519, Length=533, Percent_Identity=36.5853658536585, Blast_Score=350, Evalue=4e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=38.0804953560372, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=35.2226720647773, Blast_Score=143, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60935; Mature: 60804

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTAAVAVRAPAHETGSYLEHGRGVRSWLFTLDHKRIGIMYLVAISACLLLGGVFALAL
CCCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMHLWNPQGALVSNDAYNKLFTLHGAVMIFLFIIPGIPAALGNFVLPLQLGAKDMAFPRV
HHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCHHCCCHH
NLLSFWLFVAGAIFFVVVLVVGGVDTGWTLYPPYSLESARGLGILLALSAVVLTGFSSIL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGVNFIATIHRMRPPGMGWFDMPLFLWALYATGVIQIISTPVLGITAAMGFLERIFHLGL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
FMPEYGGDPILFQHFFWFYSHPAVYIMILPAMGVVSEVVSVFSRKPIFGYRFIAVSSMAI
CCCCCCCCHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AIIGFLVWGHHMFVSGQSRWASLAFSFLTMLVSIPSAIKTFNWIATMYKGAIVLKTPMVY
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHH
VLTFFAIFGVGGLTGLFLGLLATDIPLHDTYFVVAHFHFVMVGAVMIAFLAGLHYWWPKM
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRMYHEGVGVTSAWLVFLGFNLTFVPQFLAGVLGMPRRYATYAPQFTAHNRLSTVGAFV
CCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
LALGLALALAGLLHSLRRGRRAPPNPWGAASLEWTVASPPTHHNFDATPRARGPYDYSGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHH
HEVSEDAGWVREEGR
HHHHHHCCCHHCCCC
>Mature Secondary Structure 
SSTAAVAVRAPAHETGSYLEHGRGVRSWLFTLDHKRIGIMYLVAISACLLLGGVFALAL
CCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMHLWNPQGALVSNDAYNKLFTLHGAVMIFLFIIPGIPAALGNFVLPLQLGAKDMAFPRV
HHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCHHCCCHH
NLLSFWLFVAGAIFFVVVLVVGGVDTGWTLYPPYSLESARGLGILLALSAVVLTGFSSIL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGVNFIATIHRMRPPGMGWFDMPLFLWALYATGVIQIISTPVLGITAAMGFLERIFHLGL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
FMPEYGGDPILFQHFFWFYSHPAVYIMILPAMGVVSEVVSVFSRKPIFGYRFIAVSSMAI
CCCCCCCCHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AIIGFLVWGHHMFVSGQSRWASLAFSFLTMLVSIPSAIKTFNWIATMYKGAIVLKTPMVY
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHH
VLTFFAIFGVGGLTGLFLGLLATDIPLHDTYFVVAHFHFVMVGAVMIAFLAGLHYWWPKM
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRMYHEGVGVTSAWLVFLGFNLTFVPQFLAGVLGMPRRYATYAPQFTAHNRLSTVGAFV
CCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
LALGLALALAGLLHSLRRGRRAPPNPWGAASLEWTVASPPTHHNFDATPRARGPYDYSGL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHH
HEVSEDAGWVREEGR
HHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]