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The map label for this gene is ywlC [H]

Identifier: 220916607

GI number: 220916607

Start: 1681455

End: 1682093

Strand: Direct

Name: ywlC [H]

Synonym: A2cp1_1501

Alternate gene names: 220916607

Gene position: 1681455-1682093 (Clockwise)

Preceding gene: 220916606

Following gene: 220916608

Centisome position: 33.43

GC content: 79.34

Gene sequence:

>639_bases
ATGGACGCCCAGCTCGAGGCCCGGGTCGCGGAGGCCGCCGCCGTGCTGCGCGCCGGCGGCATCGTGGTCTATCCCACCGA
GACGTTCTACGGGCTCGGCGCGCTCGCCTCCGACGACGCCGCGCTCGTCCGGCTCGCCGCCGCGAAGCTGCGGCCCGAGG
GGAAGCCCCTGCCGCTCGTCGCGGCCGACCGGGAGCAGGTGGACCGCGTGGCGTCGCTGGAGGGCGCGGCGGCGCGGCTG
GCCGGGCGCCTGTGGCCGGGCCCGCTCACGCTGGTGCTCCCGGCGCGGCCGGGCCTGTCCGAGGCCATCACCGCGGGCTC
CGGCACGGTCGGGGTGCGGATCCCCGGGTCGGAGGTGGCGCGCGCGCTGGCGCGCATGGCTGGCGGGGCGCTGGTCTCCA
CCTCGGCGAACCTCTCCGGCGGTCCGCCGCCGGACCGGGTCGAGGCGCTCGACGCCGCGCTGCGCGGGCAGGTCGACCAC
GTGCTCGACGCCGGTCCGACGCCCGGGGGCCTCCCGAGCACCGTGGTGGCGATCGCCGGCGAGACGCTGCGGGTGGTGCG
GCCCGGCGCCGTGTCCATCGAGCAGGTGACCGCGGCGCTCGGTGGCCCCACCGGCGCCTTGCACCGTACGGGGCCGTGA

Upstream 100 bases:

>100_bases
CGACTACATCGACCGCTGGTCGCTCTGGCAGGACATGCGGATCGTGCTGCGCACCATCCCGGCGGTGCTGCTCGGGCGCG
GCGCGCGGTAGAGTCCGCGC

Downstream 100 bases:

>100_bases
TCTACGGTCCGGGGCCCCATGGCCGAGATCGTCCCGTTTCGCGGCGTCCGCTACGCCGCCACCCGCGGCCGGGCCCTCGG
CCAGCTGCTGGCCCCGCCCT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MDAQLEARVAEAAAVLRAGGIVVYPTETFYGLGALASDDAALVRLAAAKLRPEGKPLPLVAADREQVDRVASLEGAAARL
AGRLWPGPLTLVLPARPGLSEAITAGSGTVGVRIPGSEVARALARMAGGALVSTSANLSGGPPPDRVEALDAALRGQVDH
VLDAGPTPGGLPSTVVAIAGETLRVVRPGAVSIEQVTAALGGPTGALHRTGP

Sequences:

>Translated_212_residues
MDAQLEARVAEAAAVLRAGGIVVYPTETFYGLGALASDDAALVRLAAAKLRPEGKPLPLVAADREQVDRVASLEGAAARL
AGRLWPGPLTLVLPARPGLSEAITAGSGTVGVRIPGSEVARALARMAGGALVSTSANLSGGPPPDRVEALDAALRGQVDH
VLDAGPTPGGLPSTVVAIAGETLRVVRPGAVSIEQVTAALGGPTGALHRTGP
>Mature_212_residues
MDAQLEARVAEAAAVLRAGGIVVYPTETFYGLGALASDDAALVRLAAAKLRPEGKPLPLVAADREQVDRVASLEGAAARL
AGRLWPGPLTLVLPARPGLSEAITAGSGTVGVRIPGSEVARALARMAGGALVSTSANLSGGPPPDRVEALDAALRGQVDH
VLDAGPTPGGLPSTVVAIAGETLRVVRPGAVSIEQVTAALGGPTGALHRTGP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=206, Percent_Identity=37.378640776699, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=28.804347826087, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367210, Length=150, Percent_Identity=35.3333333333333, Blast_Score=80, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17537239, Length=198, Percent_Identity=32.3232323232323, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=226, Percent_Identity=33.1858407079646, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI78707274, Length=180, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 21113; Mature: 21113

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQLEARVAEAAAVLRAGGIVVYPTETFYGLGALASDDAALVRLAAAKLRPEGKPLPLV
CCCHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AADREQVDRVASLEGAAARLAGRLWPGPLTLVLPARPGLSEAITAGSGTVGVRIPGSEVA
ECCHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCEEEEEECHHHHH
RALARMAGGALVSTSANLSGGPPPDRVEALDAALRGQVDHVLDAGPTPGGLPSTVVAIAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHCC
ETLRVVRPGAVSIEQVTAALGGPTGALHRTGP
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDAQLEARVAEAAAVLRAGGIVVYPTETFYGLGALASDDAALVRLAAAKLRPEGKPLPLV
CCCHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AADREQVDRVASLEGAAARLAGRLWPGPLTLVLPARPGLSEAITAGSGTVGVRIPGSEVA
ECCHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCEEEEEECHHHHH
RALARMAGGALVSTSANLSGGPPPDRVEALDAALRGQVDHVLDAGPTPGGLPSTVVAIAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHCC
ETLRVVRPGAVSIEQVTAALGGPTGALHRTGP
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]