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The map label for this gene is yngJ [H]

Identifier: 220916367

GI number: 220916367

Start: 1413298

End: 1414455

Strand: Direct

Name: yngJ [H]

Synonym: A2cp1_1261

Alternate gene names: 220916367

Gene position: 1413298-1414455 (Clockwise)

Preceding gene: 220916366

Following gene: 220916368

Centisome position: 28.1

GC content: 74.01

Gene sequence:

>1158_bases
ATGGGCGCGCCGGCGGTCGCGTTCGAGCCGTTCACCGAGGACCACCAGGCGTTCCGCCGGACGGTCCGCGCGTTCGTGGA
CCAGGAGCTCGCGCCGCACGGGCGCGAGTGGGACGAGGCGGGGAGCTTCCCGCGCGCGCTGTTCCGCCGCTTCGGCGAGC
TGGGCCTGTTCGGCATCCGGCAGCCGCCGGAGGTGGGCGGCTCGGGGCTCGACTGGTGGTACGTCGTCGCCTACGCGGAG
GAGCTGGCGCGCTGCCGCAACGCCGGCCTGGCCGTCTCCATGCTGGTGCACGGGGAGATGGCCATCCCGGTGATCGGGGA
GCTCGGCACCGAGGCGCAGCGCCGGGAGTTCCTGGCGCCCGCGGTCCGGGGCGAGCGGGTGGCGGCGCTCGCGATCTCCG
AGCCGGACGCCGGCTCCGACGTGGCGGCCATCCGCACCACCGCGCGGCGAGACGGCGCCGACCTCGTGGTGAACGGCTCG
AAGATGTGGATCACGAACGGCGCGCGGGCCGACTTCCTCACCCTGGCCGTGCGCACCGGCGAGGCCGGCCACGGCGGGCT
CTCGCTGCTGCTGTTCCCCACCGACGTGAAGGGCTTCCAGGTCTCGCGCACGCTGGAGAAGGTGGGGCTGCCCTCGTCGG
ACACCGCGGTGCTGTTCTTCGAGGACTGCCGGGTGCCGGCGGCGAACCTGCTCGGCGAGCAGGATCAGGGCTTCTACCAC
GTCATGGCGAACTTCCAGGGCGAGCGGCTGGTGGCGGCCGTCCAGGCCGTCGCCGGGATGCAGCTCATGCTGGAGGACGC
GATGCGCTACGGCGGCGAGCGCAGCGCGTTCGGCCGGCCGGTCGCGAAGTTCCAGGCCTGGCGGCACCGGCTCGCGGATC
ACCTCACCGCGGTCGAGGCGGCGCGCTGGCTCACCTACCGGGCGGCCGACCTGCTGGCGCGGGGCGAGCCGGCGGTGCGC
GAGATCTCGATGGCGAAGCTGTTCGCCTGCGAGCTGGCCCAGCGGGTGGCCTACGACTGCATGCAGCTCCACGGCGGCAT
GGGCTACGTGCTGGAGAGCGACATCGCCCGCGCCTGGCGCGACGTGCGGGCCATGACCATCGCCGGCGGCACGTCCGAGA
TCATGCGCGAGCTGGTGTCGCGCGCGGCGGGGCTGTGA

Upstream 100 bases:

>100_bases
GGCAAGGCGTTCGCCGACGCGCTCTTCCGCAACTGGCTCGGCCGGAAGCCCGCCGACGACGACCTGAAGCGCCGCATGCT
CGGGAAGTAGCGGAGCGACC

Downstream 100 bases:

>100_bases
CGCGGCGAGCGGGCGGCCGGAGGGCGGGATGACGGAGGCGCGGGTGGTGCTCGTGACCGCGCCCGACGCGGACGTCGCCG
CGCGGCTGGCGCGGGCGCTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MGAPAVAFEPFTEDHQAFRRTVRAFVDQELAPHGREWDEAGSFPRALFRRFGELGLFGIRQPPEVGGSGLDWWYVVAYAE
ELARCRNAGLAVSMLVHGEMAIPVIGELGTEAQRREFLAPAVRGERVAALAISEPDAGSDVAAIRTTARRDGADLVVNGS
KMWITNGARADFLTLAVRTGEAGHGGLSLLLFPTDVKGFQVSRTLEKVGLPSSDTAVLFFEDCRVPAANLLGEQDQGFYH
VMANFQGERLVAAVQAVAGMQLMLEDAMRYGGERSAFGRPVAKFQAWRHRLADHLTAVEAARWLTYRAADLLARGEPAVR
EISMAKLFACELAQRVAYDCMQLHGGMGYVLESDIARAWRDVRAMTIAGGTSEIMRELVSRAAGL

Sequences:

>Translated_385_residues
MGAPAVAFEPFTEDHQAFRRTVRAFVDQELAPHGREWDEAGSFPRALFRRFGELGLFGIRQPPEVGGSGLDWWYVVAYAE
ELARCRNAGLAVSMLVHGEMAIPVIGELGTEAQRREFLAPAVRGERVAALAISEPDAGSDVAAIRTTARRDGADLVVNGS
KMWITNGARADFLTLAVRTGEAGHGGLSLLLFPTDVKGFQVSRTLEKVGLPSSDTAVLFFEDCRVPAANLLGEQDQGFYH
VMANFQGERLVAAVQAVAGMQLMLEDAMRYGGERSAFGRPVAKFQAWRHRLADHLTAVEAARWLTYRAADLLARGEPAVR
EISMAKLFACELAQRVAYDCMQLHGGMGYVLESDIARAWRDVRAMTIAGGTSEIMRELVSRAAGL
>Mature_384_residues
GAPAVAFEPFTEDHQAFRRTVRAFVDQELAPHGREWDEAGSFPRALFRRFGELGLFGIRQPPEVGGSGLDWWYVVAYAEE
LARCRNAGLAVSMLVHGEMAIPVIGELGTEAQRREFLAPAVRGERVAALAISEPDAGSDVAAIRTTARRDGADLVVNGSK
MWITNGARADFLTLAVRTGEAGHGGLSLLLFPTDVKGFQVSRTLEKVGLPSSDTAVLFFEDCRVPAANLLGEQDQGFYHV
MANFQGERLVAAVQAVAGMQLMLEDAMRYGGERSAFGRPVAKFQAWRHRLADHLTAVEAARWLTYRAADLLARGEPAVRE
ISMAKLFACELAQRVAYDCMQLHGGMGYVLESDIARAWRDVRAMTIAGGTSEIMRELVSRAAGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=39.4666666666667, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=34.6456692913386, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=37.8378378378378, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=35.3982300884956, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=32.8, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4557231, Length=384, Percent_Identity=34.1145833333333, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI187960098, Length=384, Percent_Identity=34.1145833333333, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=32.3529411764706, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=27.979274611399, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=30.9037900874636, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=30.9037900874636, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4503943, Length=386, Percent_Identity=26.6839378238342, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7669494, Length=370, Percent_Identity=26.4864864864865, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38505218, Length=337, Percent_Identity=26.4094955489614, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI211971008, Length=314, Percent_Identity=28.9808917197452, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI48976061, Length=314, Percent_Identity=28.9808917197452, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=369, Percent_Identity=27.6422764227642, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=27.2988505747126, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=36.8, Blast_Score=271, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=36.2666666666667, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=33.6, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=32, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=30.9139784946237, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=31.9148936170213, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17533517, Length=382, Percent_Identity=31.151832460733, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=35.9712230215827, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=30.1047120418848, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=30.1047120418848, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=29.3447293447293, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=28.7719298245614, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=28, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=28.82096069869, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=26.246719160105, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=27.1966527196653, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=291, Percent_Identity=26.1168384879725, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=38.2585751978892, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=37.5335120643432, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=35.5614973262032, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.8707124010554, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=33.2446808510638, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281363737, Length=351, Percent_Identity=29.3447293447293, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=24.9336870026525, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41998; Mature: 41867

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPAVAFEPFTEDHQAFRRTVRAFVDQELAPHGREWDEAGSFPRALFRRFGELGLFGIR
CCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHCCCCCCCCC
QPPEVGGSGLDWWYVVAYAEELARCRNAGLAVSMLVHGEMAIPVIGELGTEAQRREFLAP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHH
AVRGERVAALAISEPDAGSDVAAIRTTARRDGADLVVNGSKMWITNGARADFLTLAVRTG
HHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEECC
EAGHGGLSLLLFPTDVKGFQVSRTLEKVGLPSSDTAVLFFEDCRVPAANLLGEQDQGFYH
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEE
VMANFQGERLVAAVQAVAGMQLMLEDAMRYGGERSAFGRPVAKFQAWRHRLADHLTAVEA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARWLTYRAADLLARGEPAVREISMAKLFACELAQRVAYDCMQLHGGMGYVLESDIARAWR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DVRAMTIAGGTSEIMRELVSRAAGL
HHHHEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GAPAVAFEPFTEDHQAFRRTVRAFVDQELAPHGREWDEAGSFPRALFRRFGELGLFGIR
CCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHCCCCCCCCC
QPPEVGGSGLDWWYVVAYAEELARCRNAGLAVSMLVHGEMAIPVIGELGTEAQRREFLAP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHH
AVRGERVAALAISEPDAGSDVAAIRTTARRDGADLVVNGSKMWITNGARADFLTLAVRTG
HHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEECC
EAGHGGLSLLLFPTDVKGFQVSRTLEKVGLPSSDTAVLFFEDCRVPAANLLGEQDQGFYH
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEE
VMANFQGERLVAAVQAVAGMQLMLEDAMRYGGERSAFGRPVAKFQAWRHRLADHLTAVEA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARWLTYRAADLLARGEPAVREISMAKLFACELAQRVAYDCMQLHGGMGYVLESDIARAWR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DVRAMTIAGGTSEIMRELVSRAAGL
HHHHEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]