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The map label for this gene is lolC [H]

Identifier: 220916313

GI number: 220916313

Start: 1355667

End: 1357634

Strand: Direct

Name: lolC [H]

Synonym: A2cp1_1207

Alternate gene names: 220916313

Gene position: 1355667-1357634 (Clockwise)

Preceding gene: 220916312

Following gene: 220916314

Centisome position: 26.96

GC content: 74.03

Gene sequence:

>1968_bases
TTGTCCGATCCCGTCCCGCACCGGCCCGGCTCCGAGCCCGGCCCCCGCCCGGCGGCCGCGCCCGGCGCCGCCTCCCGCGA
CGGCGCCGCCCACCCGGTGCCGCCGGTCTTCTCCTTCGCCGCGTTCGCGCTGGTGCTGGCGGGCGTGTTCGGCGCCGCCG
CGGTGGCGCCGGTGGCGCACGCCTTCTTCGGCGACCGGCTGGGCCTCCCCACGCCGCTCGCCAGCGGCCTCGCCGCGCTC
GCCGGCGCCGCGCTCGGCGGCGCGTTCGGCGCCGCGGCCGCGCGGGTGGGCCGGCGCCTCGCGTTCTACGAGCTCTCCGC
CGCCACGCTGCTGTGGACCGCGGTGGTCGCGGTGCTGGTGGGCGTGCTGCCGCCGGGCGTCCGCGGCGCGGTGGGCGCGA
TCCAGGCGCTCGAGGCCCAGGGCACGCTGGTGGTGGTGCTCGGGCTGCTCGGGGCCGGCCTGCTCTCGGCGGTGGCGGTG
TTCGCGGGGGCGAGCCTCGCGTACCTGCTGGCGGGCGCCGGCCGCGTGGACGCCTCGCTCTCCTACGAGCTGTTCGTGGC
GCGCAGCCACCTGAAGCTCTCGCCGAAGGCGCTGGCGGCGCTGTTCGCGGTGGTGGTGACCGGGCTGCTCCCGGGCCTGC
TCCTCGCGCTCGCGTGGTCGCTCGTCCGCGACGCCCGGGAGCGGCGCGCCTACCGCCGCGGCGAGCTGTTCCACCGCCCG
CGCATGCCGGCCACGCTGCTCATGACGCTCATCTCGATCGGCGGCGTCGCCATCGGCGTGTGGGCGCTCACGGTGGTGCT
GTCGGTGATGAGCGGCTTCGAGGCCGACCTGAAGAAGAAGATCCTGGGCCACACCGCGCACGGCATGGTGCTGAGCTACG
GGCAGGACGACTTCGGCGACTGGCGCCGCATCCGCGAGACGGTGCTGGGGGTGCGTGGCGTCGAGGCGGCCACGCCGTTC
CTCTACAACGAGGTGATGCTCTCCACCGGCCAGAACCTGACCGGCGCGATCCTGAAGGGCATCGACGTGAAGACGATCGG
GTCGGTCACCGACCTGCCCGCGAGCGTGCAGGACGGCCGGCTGGAGTGGCTGGAGGCGCCGGCGGAGATCCCGCTGCCCC
GCGAGGGCGGGAACGGCGACGCCGGGGCCGCGCCGGAGCGGCCGCGCCCCGGCCGGCCGCTGCCCGGGATCGTGATCGGG
CGCGAGCTGGCGCACGCGCTCCGGGTCTTCGTGGGCGACCAGGTGAACCTGGTCTCGCCGTTCGGCGACCTCGGCCCCGG
CGGGCCGCAGCCGAAGAGCCGGCCGTTCCGCGTGGCGGCGGTGTTCTACAGCGGCATGTACGAGTACGACTCGAAGTTCG
CGTACATCTCGCTGCCCGAGGCGCAGCGGTTCTTCGGCGTGGAGACGGTCACCGGGCTCGAGGTGAAGGTGCGCGACGCC
GACGCCGCGCGCTCGGTCATGGGCCGGGTGGTGTTCGCGCTCGGCGGCTGGCCCTACCGCGCCAAGGACTGGGGCGAGCT
GAACCGCAGCCTCTTCTCCGCGCTGCAGATGGAGAAGGTGGTGATGGCGGTGATCCTCGGCTTCATCGTGCTGGTGGCGA
GCTTCATCATCGTCGCCACCCTCATCATGCAGGTGCTGGAGAAGCGGCGGGAGATCGCGGTGCTGAAGTCGATGGGCGCC
GGGGTGCCCAGCGTCATGAAGATCTTCGTGGTGGAGGGCGTGGTGATCGGGGCGGTGGGCACGCTCTTCGGCCTGCTGCT
CGGGCTCGGCACCTGCCTCCTCATCGACAAGGTCGGCATCCCGCTCGACCCGGGCGTCTACTACATCTCCAACCTTCCGG
TGCTGCTCGACGGCGCGCAGTTCACGCTGGTCGGCCTGGCCGCGCTCGCGCTCTCGTACCTCGCCACCATCTACCCCGCC
ACCAAGGCGGCCCGCCTCCACCCCGTGGACGGGCTGCGGGACGAGTGA

Upstream 100 bases:

>100_bases
GCGAGGGGATCGGCATCGATCGCCTGGCCATGCTCTTCACCGACTCGGCGTCCATCCGCGACGTGATCCTGTTCCCGCTG
CTGAAGTCCCGCGACTGACC

Downstream 100 bases:

>100_bases
TGCAGCCCGCGCCGCTCATCCGCATCGAGGGTCTGGGGAAGACCTACCTCATGGGCGAGAAGCGCCTGGAGGTGCTCCGC
GGGATCGACCTGGAGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MSDPVPHRPGSEPGPRPAAAPGAASRDGAAHPVPPVFSFAAFALVLAGVFGAAAVAPVAHAFFGDRLGLPTPLASGLAAL
AGAALGGAFGAAAARVGRRLAFYELSAATLLWTAVVAVLVGVLPPGVRGAVGAIQALEAQGTLVVVLGLLGAGLLSAVAV
FAGASLAYLLAGAGRVDASLSYELFVARSHLKLSPKALAALFAVVVTGLLPGLLLALAWSLVRDARERRAYRRGELFHRP
RMPATLLMTLISIGGVAIGVWALTVVLSVMSGFEADLKKKILGHTAHGMVLSYGQDDFGDWRRIRETVLGVRGVEAATPF
LYNEVMLSTGQNLTGAILKGIDVKTIGSVTDLPASVQDGRLEWLEAPAEIPLPREGGNGDAGAAPERPRPGRPLPGIVIG
RELAHALRVFVGDQVNLVSPFGDLGPGGPQPKSRPFRVAAVFYSGMYEYDSKFAYISLPEAQRFFGVETVTGLEVKVRDA
DAARSVMGRVVFALGGWPYRAKDWGELNRSLFSALQMEKVVMAVILGFIVLVASFIIVATLIMQVLEKRREIAVLKSMGA
GVPSVMKIFVVEGVVIGAVGTLFGLLLGLGTCLLIDKVGIPLDPGVYYISNLPVLLDGAQFTLVGLAALALSYLATIYPA
TKAARLHPVDGLRDE

Sequences:

>Translated_655_residues
MSDPVPHRPGSEPGPRPAAAPGAASRDGAAHPVPPVFSFAAFALVLAGVFGAAAVAPVAHAFFGDRLGLPTPLASGLAAL
AGAALGGAFGAAAARVGRRLAFYELSAATLLWTAVVAVLVGVLPPGVRGAVGAIQALEAQGTLVVVLGLLGAGLLSAVAV
FAGASLAYLLAGAGRVDASLSYELFVARSHLKLSPKALAALFAVVVTGLLPGLLLALAWSLVRDARERRAYRRGELFHRP
RMPATLLMTLISIGGVAIGVWALTVVLSVMSGFEADLKKKILGHTAHGMVLSYGQDDFGDWRRIRETVLGVRGVEAATPF
LYNEVMLSTGQNLTGAILKGIDVKTIGSVTDLPASVQDGRLEWLEAPAEIPLPREGGNGDAGAAPERPRPGRPLPGIVIG
RELAHALRVFVGDQVNLVSPFGDLGPGGPQPKSRPFRVAAVFYSGMYEYDSKFAYISLPEAQRFFGVETVTGLEVKVRDA
DAARSVMGRVVFALGGWPYRAKDWGELNRSLFSALQMEKVVMAVILGFIVLVASFIIVATLIMQVLEKRREIAVLKSMGA
GVPSVMKIFVVEGVVIGAVGTLFGLLLGLGTCLLIDKVGIPLDPGVYYISNLPVLLDGAQFTLVGLAALALSYLATIYPA
TKAARLHPVDGLRDE
>Mature_654_residues
SDPVPHRPGSEPGPRPAAAPGAASRDGAAHPVPPVFSFAAFALVLAGVFGAAAVAPVAHAFFGDRLGLPTPLASGLAALA
GAALGGAFGAAAARVGRRLAFYELSAATLLWTAVVAVLVGVLPPGVRGAVGAIQALEAQGTLVVVLGLLGAGLLSAVAVF
AGASLAYLLAGAGRVDASLSYELFVARSHLKLSPKALAALFAVVVTGLLPGLLLALAWSLVRDARERRAYRRGELFHRPR
MPATLLMTLISIGGVAIGVWALTVVLSVMSGFEADLKKKILGHTAHGMVLSYGQDDFGDWRRIRETVLGVRGVEAATPFL
YNEVMLSTGQNLTGAILKGIDVKTIGSVTDLPASVQDGRLEWLEAPAEIPLPREGGNGDAGAAPERPRPGRPLPGIVIGR
ELAHALRVFVGDQVNLVSPFGDLGPGGPQPKSRPFRVAAVFYSGMYEYDSKFAYISLPEAQRFFGVETVTGLEVKVRDAD
AARSVMGRVVFALGGWPYRAKDWGELNRSLFSALQMEKVVMAVILGFIVLVASFIIVATLIMQVLEKRREIAVLKSMGAG
VPSVMKIFVVEGVVIGAVGTLFGLLLGLGTCLLIDKVGIPLDPGVYYISNLPVLLDGAQFTLVGLAALALSYLATIYPAT
KAARLHPVDGLRDE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=413, Percent_Identity=29.7820823244552, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1787360, Length=412, Percent_Identity=27.4271844660194, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 68380; Mature: 68249

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPVPHRPGSEPGPRPAAAPGAASRDGAAHPVPPVFSFAAFALVLAGVFGAAAVAPVAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFFGDRLGLPTPLASGLAALAGAALGGAFGAAAARVGRRLAFYELSAATLLWTAVVAVLV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLPPGVRGAVGAIQALEAQGTLVVVLGLLGAGLLSAVAVFAGASLAYLLAGAGRVDASL
HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYELFVARSHLKLSPKALAALFAVVVTGLLPGLLLALAWSLVRDARERRAYRRGELFHRP
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RMPATLLMTLISIGGVAIGVWALTVVLSVMSGFEADLKKKILGHTAHGMVLSYGQDDFGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEECCCCCHHH
WRRIRETVLGVRGVEAATPFLYNEVMLSTGQNLTGAILKGIDVKTIGSVTDLPASVQDGR
HHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCHHHHHHCCCCHHHCCCHHCCCCCCCCCC
LEWLEAPAEIPLPREGGNGDAGAAPERPRPGRPLPGIVIGRELAHALRVFVGDQVNLVSP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
FGDLGPGGPQPKSRPFRVAAVFYSGMYEYDSKFAYISLPEAQRFFGVETVTGLEVKVRDA
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEECCCHHHHHCCCEECCCEEEEECH
DAARSVMGRVVFALGGWPYRAKDWGELNRSLFSALQMEKVVMAVILGFIVLVASFIIVAT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMQVLEKRREIAVLKSMGAGVPSVMKIFVVEGVVIGAVGTLFGLLLGLGTCLLIDKVGI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLDPGVYYISNLPVLLDGAQFTLVGLAALALSYLATIYPATKAARLHPVDGLRDE
CCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDPVPHRPGSEPGPRPAAAPGAASRDGAAHPVPPVFSFAAFALVLAGVFGAAAVAPVAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFFGDRLGLPTPLASGLAALAGAALGGAFGAAAARVGRRLAFYELSAATLLWTAVVAVLV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLPPGVRGAVGAIQALEAQGTLVVVLGLLGAGLLSAVAVFAGASLAYLLAGAGRVDASL
HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYELFVARSHLKLSPKALAALFAVVVTGLLPGLLLALAWSLVRDARERRAYRRGELFHRP
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RMPATLLMTLISIGGVAIGVWALTVVLSVMSGFEADLKKKILGHTAHGMVLSYGQDDFGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEECCCCCHHH
WRRIRETVLGVRGVEAATPFLYNEVMLSTGQNLTGAILKGIDVKTIGSVTDLPASVQDGR
HHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCHHHHHHCCCCHHHCCCHHCCCCCCCCCC
LEWLEAPAEIPLPREGGNGDAGAAPERPRPGRPLPGIVIGRELAHALRVFVGDQVNLVSP
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
FGDLGPGGPQPKSRPFRVAAVFYSGMYEYDSKFAYISLPEAQRFFGVETVTGLEVKVRDA
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCEEEEECCCHHHHHCCCEECCCEEEEECH
DAARSVMGRVVFALGGWPYRAKDWGELNRSLFSALQMEKVVMAVILGFIVLVASFIIVAT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMQVLEKRREIAVLKSMGAGVPSVMKIFVVEGVVIGAVGTLFGLLLGLGTCLLIDKVGI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLDPGVYYISNLPVLLDGAQFTLVGLAALALSYLATIYPATKAARLHPVDGLRDE
CCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]