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The map label for this gene is lhr [C]

Identifier: 220916267

GI number: 220916267

Start: 1298935

End: 1301040

Strand: Direct

Name: lhr [C]

Synonym: A2cp1_1160

Alternate gene names: 220916267

Gene position: 1298935-1301040 (Clockwise)

Preceding gene: 220916266

Following gene: 220916269

Centisome position: 25.83

GC content: 67.81

Gene sequence:

>2106_bases
GTGAGCGCGTTCTCACGGTTCCCCGCCCGGCTGCAGCAGGCGATCGTCTCGCGCCTCGGGTGGACGGCGCTGCGTGCGGT
GCAGGAGCTCGCGGGCGAGGCGATCCTCGATGGGAAGAACGCGGTCGTGCTCGCGCCGACCGCAGGCGGCAAGACGGAGG
CGTCCATCTTCCCGGCGCTCGCGAACCTCGTCGAGAACGGGTGTGAAGGCGTCGGCGTGGTCTACGTCGCGCCCATCAAG
GCACTCCTCAACAACCAAGAGGAACGGCTCGGCACGTACACGGAGATGGTCGGCCTGCGCCGCTTCGTGTGGCACGGGGA
CGTGCCGGACCGGGACAAGCGCGAGTTCGTTCGGGAGCCCGCCGAGCTCCTGATGACGACGCCCGAGTCGCTCGAGGTGA
TGCTGCTCTCGCCGCGCTTCCCGACGCCGAAGGTCTTTCCCGACCTTCGCATGGTGATCGTCGACGAGGTGCACGCGTTC
GCTGGGACCGAGCGCGGCGCACACCTCATGAGCGTCCTCGAGCGGCTCATCAAGAGCACGAAGAATGACGTCCAGCGGAT
CGGGCTGAGCGCGACTGTCGGAAACCCGGAGGAAATCCTCGGATGGTTGCAGGGGACGTCGCGCCGGGCCGGCGTGGTCG
TCGATCCGCCGAAGGTGTCCGCCCGGCGCGAGTTGCACGTTTCACTCCACGAGAGCGTCATCGACATCGCCCGGGACGCG
GCTCGGCGTGCTGCGGGGAACAAGAGCCTGTTCTTCTGCCAGAGCCGCGCGTTGACCGAGTCCGTCGCTGAGAGGATGCG
TGGGCACGGGACGGAGGTGTTCGTTCATCACGGCTCGGTGTCACGTGAGGAGCGCCACGACGCGGAGGCGCAATTCAACC
ACGGTACGAACGCCTGCATCGTCTGCACGTCGACCCTCGAGCTCGGGATCGACGTAGGAGATCTCGACCTCGTGATGCAG
GCGAATGCCCCGAGCACCGTTTCGTCGTTCCTCCAGCGCATGGGCCGGACGGGCCGGCGCGCCGGGCAGACCGCGAACAC
GAGCTTTTTCTGCGAGGACGAGGACGCGGCGCTCCAGGCGGTCGCGCTCGTCGAGCTCGCGCGCGAGGGCTGGGTGGAGC
GGGTGCCAGCCGCACGCCGGTGCTGGCCGGTGTTCGCGCACCAGATCTTCGCGCTAACGCTGCAGTACGGAGCGGTGAGC
CCGGAGCGCTGCTGGGAGCACCTCCACGTCGTGCGGGACTTCGCGGACATCAGCCGCGACGAGTTCGAGCGCGTGCTCGA
CCACATGAAGCGCCACGAGTACCTCTTCGAGTCCGGCGGCCTCCTCTCGCTGGGCCAGAAGGCCGAGCGGGTCTACGGGA
AGCGGAACTTCCTCGAGCTGTACGCGGTGTTCTCGAGCCCGGTGCTGTACCAGGTCGAGACTGCCGCTGGCCGGGCGCTC
GGCTCCCTCGAGCAGAACTTCGTGGACCAGCTCGTCGAGGAGATGAGCGCGTTCCTTCTCGCTGGTCGCGCGTGGCTCGT
CGAACACGTGCACCACGAGGACCGCGTCGTCCGCGTCCGAGAGGCGCCGCGAGGCCAGAAGCCGAGCTGGGGTGGATTCG
CGCCTTCCCTGCTCGGGTTCGAGATCTGCCAGCGCATGAAGCGCGTCCTGACCGACTCGACGCCGGTTCCCTACGCGGAC
GCTGCCGCGATGCGCGCGATCGAGGCCCGCCGCAAAGACCTCGGGGATACCCTGCGGCGGCCCATCGCGATGCAAACGGA
CGAGGGGGTGGTGCGGTGGTGGACGTTCGCCGGGGGCAAGATTAACCAGACCCTCAAATACGGGCTCGAGTGGAGTCACG
ACTGGTCGGTGAAGGGCGATAACTTCGAACTGCGGATCTCGGGCGCGGGGGTATCGGACGGTGCCGTCCGCGAGGCCATC
CGCGAGGTGTCTTCGGCTGCGTTCTGGGACAAGCCGGAGACCAGATCGGCGATTCTTGGTCGGCTTCCGGCGTACCGCCT
GAGCAAGTTCCAGGACGCGCTGCCCGACGTGTTCGCTGTAGAGCTGGTGGGCAACTACTTGCTAGACGTGCCGCGCGCGC
AGGCGTTCGCGCAGTCGGTCCTCTGA

Upstream 100 bases:

>100_bases
CGAGTGACTACGAGGCGCGCAAGCTCGAGGGGAAGCCTCCGTACGACCCCGAGCCCGGTGACGACAAGGGATACCCGACG
ACGTCCGTGGAGTTCTGAGC

Downstream 100 bases:

>100_bases
GGGGACGTCGTTGCGGCCGTAGCGCTCCACGGCTTCGTCGACCAGCTTCTTGGCCTGCCGTGGTCGGTGACGTCCGGTTG
GCCGAAGGATGGGGGTCAGC

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MSAFSRFPARLQQAIVSRLGWTALRAVQELAGEAILDGKNAVVLAPTAGGKTEASIFPALANLVENGCEGVGVVYVAPIK
ALLNNQEERLGTYTEMVGLRRFVWHGDVPDRDKREFVREPAELLMTTPESLEVMLLSPRFPTPKVFPDLRMVIVDEVHAF
AGTERGAHLMSVLERLIKSTKNDVQRIGLSATVGNPEEILGWLQGTSRRAGVVVDPPKVSARRELHVSLHESVIDIARDA
ARRAAGNKSLFFCQSRALTESVAERMRGHGTEVFVHHGSVSREERHDAEAQFNHGTNACIVCTSTLELGIDVGDLDLVMQ
ANAPSTVSSFLQRMGRTGRRAGQTANTSFFCEDEDAALQAVALVELAREGWVERVPAARRCWPVFAHQIFALTLQYGAVS
PERCWEHLHVVRDFADISRDEFERVLDHMKRHEYLFESGGLLSLGQKAERVYGKRNFLELYAVFSSPVLYQVETAAGRAL
GSLEQNFVDQLVEEMSAFLLAGRAWLVEHVHHEDRVVRVREAPRGQKPSWGGFAPSLLGFEICQRMKRVLTDSTPVPYAD
AAAMRAIEARRKDLGDTLRRPIAMQTDEGVVRWWTFAGGKINQTLKYGLEWSHDWSVKGDNFELRISGAGVSDGAVREAI
REVSSAAFWDKPETRSAILGRLPAYRLSKFQDALPDVFAVELVGNYLLDVPRAQAFAQSVL

Sequences:

>Translated_701_residues
MSAFSRFPARLQQAIVSRLGWTALRAVQELAGEAILDGKNAVVLAPTAGGKTEASIFPALANLVENGCEGVGVVYVAPIK
ALLNNQEERLGTYTEMVGLRRFVWHGDVPDRDKREFVREPAELLMTTPESLEVMLLSPRFPTPKVFPDLRMVIVDEVHAF
AGTERGAHLMSVLERLIKSTKNDVQRIGLSATVGNPEEILGWLQGTSRRAGVVVDPPKVSARRELHVSLHESVIDIARDA
ARRAAGNKSLFFCQSRALTESVAERMRGHGTEVFVHHGSVSREERHDAEAQFNHGTNACIVCTSTLELGIDVGDLDLVMQ
ANAPSTVSSFLQRMGRTGRRAGQTANTSFFCEDEDAALQAVALVELAREGWVERVPAARRCWPVFAHQIFALTLQYGAVS
PERCWEHLHVVRDFADISRDEFERVLDHMKRHEYLFESGGLLSLGQKAERVYGKRNFLELYAVFSSPVLYQVETAAGRAL
GSLEQNFVDQLVEEMSAFLLAGRAWLVEHVHHEDRVVRVREAPRGQKPSWGGFAPSLLGFEICQRMKRVLTDSTPVPYAD
AAAMRAIEARRKDLGDTLRRPIAMQTDEGVVRWWTFAGGKINQTLKYGLEWSHDWSVKGDNFELRISGAGVSDGAVREAI
REVSSAAFWDKPETRSAILGRLPAYRLSKFQDALPDVFAVELVGNYLLDVPRAQAFAQSVL
>Mature_700_residues
SAFSRFPARLQQAIVSRLGWTALRAVQELAGEAILDGKNAVVLAPTAGGKTEASIFPALANLVENGCEGVGVVYVAPIKA
LLNNQEERLGTYTEMVGLRRFVWHGDVPDRDKREFVREPAELLMTTPESLEVMLLSPRFPTPKVFPDLRMVIVDEVHAFA
GTERGAHLMSVLERLIKSTKNDVQRIGLSATVGNPEEILGWLQGTSRRAGVVVDPPKVSARRELHVSLHESVIDIARDAA
RRAAGNKSLFFCQSRALTESVAERMRGHGTEVFVHHGSVSREERHDAEAQFNHGTNACIVCTSTLELGIDVGDLDLVMQA
NAPSTVSSFLQRMGRTGRRAGQTANTSFFCEDEDAALQAVALVELAREGWVERVPAARRCWPVFAHQIFALTLQYGAVSP
ERCWEHLHVVRDFADISRDEFERVLDHMKRHEYLFESGGLLSLGQKAERVYGKRNFLELYAVFSSPVLYQVETAAGRALG
SLEQNFVDQLVEEMSAFLLAGRAWLVEHVHHEDRVVRVREAPRGQKPSWGGFAPSLLGFEICQRMKRVLTDSTPVPYADA
AAMRAIEARRKDLGDTLRRPIAMQTDEGVVRWWTFAGGKINQTLKYGLEWSHDWSVKGDNFELRISGAGVSDGAVREAIR
EVSSAAFWDKPETRSAILGRLPAYRLSKFQDALPDVFAVELVGNYLLDVPRAQAFAQSVL

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=375, Percent_Identity=22.9333333333333, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI38569505, Length=375, Percent_Identity=22.9333333333333, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI262118318, Length=389, Percent_Identity=22.879177377892, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI262231852, Length=389, Percent_Identity=22.879177377892, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI216548263, Length=389, Percent_Identity=22.879177377892, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI13518015, Length=389, Percent_Identity=22.879177377892, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI13129006, Length=363, Percent_Identity=23.1404958677686, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI50659095, Length=399, Percent_Identity=22.3057644110276, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787942, Length=589, Percent_Identity=27.6740237691002, Blast_Score=172, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17556951, Length=350, Percent_Identity=22.8571428571429, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=348, Percent_Identity=21.8390804597701, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555296, Length=335, Percent_Identity=25.0746268656716, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987993, Length=367, Percent_Identity=24.5231607629428, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987997, Length=376, Percent_Identity=25, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532546, Length=349, Percent_Identity=23.2091690544413, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552114, Length=329, Percent_Identity=19.7568389057751, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507877, Length=370, Percent_Identity=22.1621621621622, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115532548, Length=349, Percent_Identity=23.2091690544413, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=371, Percent_Identity=21.0242587601078, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=350, Percent_Identity=24.8571428571429, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324217, Length=352, Percent_Identity=22.1590909090909, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=335, Percent_Identity=20.8955223880597, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320400, Length=365, Percent_Identity=21.9178082191781, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320224, Length=356, Percent_Identity=19.9438202247191, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666101, Length=371, Percent_Identity=24.5283018867925, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17985987, Length=360, Percent_Identity=23.0555555555556, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 77861; Mature: 77729

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFSRFPARLQQAIVSRLGWTALRAVQELAGEAILDGKNAVVLAPTAGGKTEASIFPAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHHHHHH
ANLVENGCEGVGVVYVAPIKALLNNQEERLGTYTEMVGLRRFVWHGDVPDRDKREFVREP
HHHHHCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCH
AELLMTTPESLEVMLLSPRFPTPKVFPDLRMVIVDEVHAFAGTERGAHLMSVLERLIKST
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KNDVQRIGLSATVGNPEEILGWLQGTSRRAGVVVDPPKVSARRELHVSLHESVIDIARDA
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
ARRAAGNKSLFFCQSRALTESVAERMRGHGTEVFVHHGSVSREERHDAEAQFNHGTNACI
HHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCHHHCCCCCCEEE
VCTSTLELGIDVGDLDLVMQANAPSTVSSFLQRMGRTGRRAGQTANTSFFCEDEDAALQA
EEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHCCCCCCCCEEECCCHHHHHH
VALVELAREGWVERVPAARRCWPVFAHQIFALTLQYGAVSPERCWEHLHVVRDFADISRD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
EFERVLDHMKRHEYLFESGGLLSLGQKAERVYGKRNFLELYAVFSSPVLYQVETAAGRAL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHH
GSLEQNFVDQLVEEMSAFLLAGRAWLVEHVHHEDRVVRVREAPRGQKPSWGGFAPSLLGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHH
EICQRMKRVLTDSTPVPYADAAAMRAIEARRKDLGDTLRRPIAMQTDEGVVRWWTFAGGK
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEECCCC
INQTLKYGLEWSHDWSVKGDNFELRISGAGVSDGAVREAIREVSSAAFWDKPETRSAILG
CCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RLPAYRLSKFQDALPDVFAVELVGNYLLDVPRAQAFAQSVL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
SAFSRFPARLQQAIVSRLGWTALRAVQELAGEAILDGKNAVVLAPTAGGKTEASIFPAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHHHHHH
ANLVENGCEGVGVVYVAPIKALLNNQEERLGTYTEMVGLRRFVWHGDVPDRDKREFVREP
HHHHHCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCH
AELLMTTPESLEVMLLSPRFPTPKVFPDLRMVIVDEVHAFAGTERGAHLMSVLERLIKST
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KNDVQRIGLSATVGNPEEILGWLQGTSRRAGVVVDPPKVSARRELHVSLHESVIDIARDA
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
ARRAAGNKSLFFCQSRALTESVAERMRGHGTEVFVHHGSVSREERHDAEAQFNHGTNACI
HHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCHHHCCCCCCEEE
VCTSTLELGIDVGDLDLVMQANAPSTVSSFLQRMGRTGRRAGQTANTSFFCEDEDAALQA
EEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHCCCCCCCCEEECCCHHHHHH
VALVELAREGWVERVPAARRCWPVFAHQIFALTLQYGAVSPERCWEHLHVVRDFADISRD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
EFERVLDHMKRHEYLFESGGLLSLGQKAERVYGKRNFLELYAVFSSPVLYQVETAAGRAL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHH
GSLEQNFVDQLVEEMSAFLLAGRAWLVEHVHHEDRVVRVREAPRGQKPSWGGFAPSLLGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHH
EICQRMKRVLTDSTPVPYADAAAMRAIEARRKDLGDTLRRPIAMQTDEGVVRWWTFAGGK
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEECCCC
INQTLKYGLEWSHDWSVKGDNFELRISGAGVSDGAVREAIREVSSAAFWDKPETRSAILG
CCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RLPAYRLSKFQDALPDVFAVELVGNYLLDVPRAQAFAQSVL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]