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The map label for this gene is virB1 [H]

Identifier: 220916240

GI number: 220916240

Start: 1267069

End: 1267719

Strand: Direct

Name: virB1 [H]

Synonym: A2cp1_1133

Alternate gene names: 220916240

Gene position: 1267069-1267719 (Clockwise)

Preceding gene: 220916239

Following gene: 220916241

Centisome position: 25.19

GC content: 71.12

Gene sequence:

>651_bases
GTGACCGGCCTCAGCGCGCTCATCGTCGCATGCGGAATCGTACGCCACGTCGGCCTGATCGAGGCCATCGTCCGGGTGGA
GTCCGGCGGCAATCCGTTCGCGCTCGCGGTAAACGGCGCAGTGGAACTGGTGCACGCGCCTCGCGATCGGGACGAAGCTG
CGGCGATGGCCCGATGGCTCGCGGCGCACGGCTACAACTTCGACGCCGGGCTCGCGCAGGTGAACAGCGCCAACCTGGCG
CGGTTCGGACTCGACACCTCCAGCGTGTTCGAGCGCTGTGCGAACCTCCGTGCAGCGAGCCGCGTGCTCGAGGAATGTCA
CGAGCGCGCGCTCCAGCACTGGGACGACGAGGAGCGCGCGATGGCGGCAGCGCTCTCCTGCTACAACACGGGCCACCTCA
CGCGCGGATTGAGGAACGGCTACGTGACCGCGGTGCGAGCGGCCGTGGACTCGCTGGCGCCGGGGCCAAATCGCGACGGA
TCGCGCGGCGACGAAGCCTGCCACGTGTGGGGTCGCTCCGCGCGCCGCAACCCGGCGCGCGGGAGCGGCCGGGCGCGGGC
AGCGATCGGCGACACCCAGCGGGACGAAGTGTTCGCGATGTCGCTGGCGGATGCCTTCGCCACGCGCTCGCACGAGGAGC
GGGTGCGATGA

Upstream 100 bases:

>100_bases
GCTCCCGCGCGCTTGACAGAGTTCGAGGCACGCCGCACCATGCCGGCATGGTAGACCGTGCCTCAATTTGTGCTGTCGCT
CTAGGCGACGGGAGGAGCGC

Downstream 100 bases:

>100_bases
CGGACGCCATCAACACGCCGCCCGCGGCCAGCAACGAAGTCATGGGCGCCCGGGCCTTCTTCCCGTGGCACGACACATAC
GGCCGAGAGCACCCGGACAT

Product: lytic transglycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTGLSALIVACGIVRHVGLIEAIVRVESGGNPFALAVNGAVELVHAPRDRDEAAAMARWLAAHGYNFDAGLAQVNSANLA
RFGLDTSSVFERCANLRAASRVLEECHERALQHWDDEERAMAAALSCYNTGHLTRGLRNGYVTAVRAAVDSLAPGPNRDG
SRGDEACHVWGRSARRNPARGSGRARAAIGDTQRDEVFAMSLADAFATRSHEERVR

Sequences:

>Translated_216_residues
MTGLSALIVACGIVRHVGLIEAIVRVESGGNPFALAVNGAVELVHAPRDRDEAAAMARWLAAHGYNFDAGLAQVNSANLA
RFGLDTSSVFERCANLRAASRVLEECHERALQHWDDEERAMAAALSCYNTGHLTRGLRNGYVTAVRAAVDSLAPGPNRDG
SRGDEACHVWGRSARRNPARGSGRARAAIGDTQRDEVFAMSLADAFATRSHEERVR
>Mature_215_residues
TGLSALIVACGIVRHVGLIEAIVRVESGGNPFALAVNGAVELVHAPRDRDEAAAMARWLAAHGYNFDAGLAQVNSANLAR
FGLDTSSVFERCANLRAASRVLEECHERALQHWDDEERAMAAALSCYNTGHLTRGLRNGYVTAVRAAVDSLAPGPNRDGS
RGDEACHVWGRSARRNPARGSGRARAAIGDTQRDEVFAMSLADAFATRSHEERVR

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virb1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 23218; Mature: 23087

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLSALIVACGIVRHVGLIEAIVRVESGGNPFALAVNGAVELVHAPRDRDEAAAMARWL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHH
AAHGYNFDAGLAQVNSANLARFGLDTSSVFERCANLRAASRVLEECHERALQHWDDEERA
HHCCCCCCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MAAALSCYNTGHLTRGLRNGYVTAVRAAVDSLAPGPNRDGSRGDEACHVWGRSARRNPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCC
GSGRARAAIGDTQRDEVFAMSLADAFATRSHEERVR
CCCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
TGLSALIVACGIVRHVGLIEAIVRVESGGNPFALAVNGAVELVHAPRDRDEAAAMARWL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHH
AAHGYNFDAGLAQVNSANLARFGLDTSSVFERCANLRAASRVLEECHERALQHWDDEERA
HHCCCCCCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MAAALSCYNTGHLTRGLRNGYVTAVRAAVDSLAPGPNRDGSRGDEACHVWGRSARRNPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCC
GSGRARAAIGDTQRDEVFAMSLADAFATRSHEERVR
CCCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]