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The map label for this gene is czcC [H]

Identifier: 220916191

GI number: 220916191

Start: 1208177

End: 1209412

Strand: Reverse

Name: czcC [H]

Synonym: A2cp1_1079

Alternate gene names: 220916191

Gene position: 1209412-1208177 (Counterclockwise)

Preceding gene: 220916192

Following gene: 220916190

Centisome position: 24.05

GC content: 81.15

Gene sequence:

>1236_bases
ATGACCCCGGCCACCCTCGCAGCCACGCTCCTCCTGGCGACCGCCGGCGCCGATGCCCTGACCTCGGAGCGTGCGGTGGC
GCTCGCGCTCGAGCGCAACCCCGAGCTCGCGGCGCTGGCCGCCGAGGCGCGCGCCGCGGAGGCGCGGCTGGAAGGGGCCC
GCGCCCCGCTGCCGTCCAATCCGGAGCTCTCGGCCGCGCTCGGGCCGCGGCGGTCCGGCGGCGAGCGCACCACCGACGTC
GAGCTCGGGCTGTCGCAGCGCCTCGAGATCTTCGGCGAGCGGAGCGCGCGCATCGACGTCGCCGCCGGCGAGCGCGACGC
CGCGTCGGCGCGCCTGGCCGCGCGGCGCGTCGAGCTCGCGGCCTCCGCCCGGGAGGCTCACGCCCGCGCCCTCGCGGCGG
AACGCCTGGCCGCGCTGGCGCGCGAGGAGCTCGCGGTCGCGCGCGAGGCCGCGCGGGCCGCGGAGCGGCGGGCGGAGCTC
GGGAGCGCCTCGCGCCTCGAGGTGAACGCGGCCCGCGGGGAGGTCGGGCGAGCGGCCCGGGCCGTCGGGACGACCGCGAG
CCGCTTGGCCGCGGCGCAGGCGGCGCTGCGGACCCTGCTCGCGGCGGAGCCGGGGGAAGGCCTCCCGCTCGCGGGCGAGC
TGCCGCGTCCCTCGGACGTCCGCCCGGCGGACGGCGAGGCGCTCGTGCGCGCCGCGGCCGAGCGGCGGGGCGACGTGGCC
GCCGCGCGCCGCTCGCTCGCGGCGGCAGAGGCCGAGCAGCGCCTGGCCCGCCGCGAGGCGCTCCCTTCCCCGGTGCTGGG
CGCCCGCTACGCGCGCGAGGAGCGTGCCGACGTGCTCCTCGGAACCCTCTCGTTCGAGCTGCCCCTGTTCGACCGCAACC
AGGCCGGCCGCGGCGCCGCCTCCGCACGGGCGGCCCGCGCCGGGGTCGAGCTCGCCGCGGCGACCCGGCGCGCCGGGGAG
GAGGTGCAGCTCGCGCTGGCGCGGCTCCGGGCGGCCACCGAGGCGGCCAGCGCCTTCGACGACGGCGCGGTCTCCGGCGC
GGAGGAGAACCTCGCGCTTTCCACGCGCGCCTACGAGGCGGGCAAGATCGGCCTCGCCGACCTCCTCCTCATGCGGCGGA
GCGCGGTCGAGGCGAGGCGCGATCACGTCGAGGCGCTCGAGGAGCTCGCCGCGGCCGAGGCCGCCCTGGCCCGGGCCGCC
GGGTCCGAGCGGCTCGTCACCCGGGACGGCAGGTGA

Upstream 100 bases:

>100_bases
GGCCTGGCGAGGCCGTCGAGGAGGGCGCGAGCGCCGGGGGACCCGAGCCGGCGCGCGATCCCGCGCCGCCGCGCGCCGCG
GCCATGCCGCGGGGGGACGC

Downstream 100 bases:

>100_bases
CCGCCGCCTGCGCGTGCTGCCGGGCATCGGCCTGGTCTCGGCGCGCGGCGCTGGCGCGGCCTGGCCCGCGTGACGAGAGT
TGCTGCACGCATGCCCCCGC

Product: sensor with HAMP domain

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTPATLAATLLLATAGADALTSERAVALALERNPELAALAAEARAAEARLEGARAPLPSNPELSAALGPRRSGGERTTDV
ELGLSQRLEIFGERSARIDVAAGERDAASARLAARRVELAASAREAHARALAAERLAALAREELAVAREAARAAERRAEL
GSASRLEVNAARGEVGRAARAVGTTASRLAAAQAALRTLLAAEPGEGLPLAGELPRPSDVRPADGEALVRAAAERRGDVA
AARRSLAAAEAEQRLARREALPSPVLGARYAREERADVLLGTLSFELPLFDRNQAGRGAASARAARAGVELAAATRRAGE
EVQLALARLRAATEAASAFDDGAVSGAEENLALSTRAYEAGKIGLADLLLMRRSAVEARRDHVEALEELAAAEAALARAA
GSERLVTRDGR

Sequences:

>Translated_411_residues
MTPATLAATLLLATAGADALTSERAVALALERNPELAALAAEARAAEARLEGARAPLPSNPELSAALGPRRSGGERTTDV
ELGLSQRLEIFGERSARIDVAAGERDAASARLAARRVELAASAREAHARALAAERLAALAREELAVAREAARAAERRAEL
GSASRLEVNAARGEVGRAARAVGTTASRLAAAQAALRTLLAAEPGEGLPLAGELPRPSDVRPADGEALVRAAAERRGDVA
AARRSLAAAEAEQRLARREALPSPVLGARYAREERADVLLGTLSFELPLFDRNQAGRGAASARAARAGVELAAATRRAGE
EVQLALARLRAATEAASAFDDGAVSGAEENLALSTRAYEAGKIGLADLLLMRRSAVEARRDHVEALEELAAAEAALARAA
GSERLVTRDGR
>Mature_410_residues
TPATLAATLLLATAGADALTSERAVALALERNPELAALAAEARAAEARLEGARAPLPSNPELSAALGPRRSGGERTTDVE
LGLSQRLEIFGERSARIDVAAGERDAASARLAARRVELAASAREAHARALAAERLAALAREELAVAREAARAAERRAELG
SASRLEVNAARGEVGRAARAVGTTASRLAAAQAALRTLLAAEPGEGLPLAGELPRPSDVRPADGEALVRAAAERRGDVAA
ARRSLAAAEAEQRLARREALPSPVLGARYAREERADVLLGTLSFELPLFDRNQAGRGAASARAARAGVELAAATRRAGEE
VQLALARLRAATEAASAFDDGAVSGAEENLALSTRAYEAGKIGLADLLLMRRSAVEARRDHVEALEELAAAEAALARAAG
SERLVTRDGR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 42555; Mature: 42424

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPATLAATLLLATAGADALTSERAVALALERNPELAALAAEARAAEARLEGARAPLPSN
CCHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PELSAALGPRRSGGERTTDVELGLSQRLEIFGERSARIDVAAGERDAASARLAARRVELA
CCCHHHCCCCCCCCCCCCCHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ASAREAHARALAAERLAALAREELAVAREAARAAERRAELGSASRLEVNAARGEVGRAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCHHHHHHH
AVGTTASRLAAAQAALRTLLAAEPGEGLPLAGELPRPSDVRPADGEALVRAAAERRGDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHH
AARRSLAAAEAEQRLARREALPSPVLGARYAREERADVLLGTLSFELPLFDRNQAGRGAA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEHEEECCCCCCCCCCCCHH
SARAARAGVELAAATRRAGEEVQLALARLRAATEAASAFDDGAVSGAEENLALSTRAYEA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHCCCC
GKIGLADLLLMRRSAVEARRDHVEALEELAAAEAALARAAGSERLVTRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TPATLAATLLLATAGADALTSERAVALALERNPELAALAAEARAAEARLEGARAPLPSN
CHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PELSAALGPRRSGGERTTDVELGLSQRLEIFGERSARIDVAAGERDAASARLAARRVELA
CCCHHHCCCCCCCCCCCCCHHHCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ASAREAHARALAAERLAALAREELAVAREAARAAERRAELGSASRLEVNAARGEVGRAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCHHHHHHH
AVGTTASRLAAAQAALRTLLAAEPGEGLPLAGELPRPSDVRPADGEALVRAAAERRGDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHH
AARRSLAAAEAEQRLARREALPSPVLGARYAREERADVLLGTLSFELPLFDRNQAGRGAA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEHEEECCCCCCCCCCCCHH
SARAARAGVELAAATRRAGEEVQLALARLRAATEAASAFDDGAVSGAEENLALSTRAYEA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHCCCC
GKIGLADLLLMRRSAVEARRDHVEALEELAAAEAALARAAGSERLVTRDGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]