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The map label for this gene is cat2 [H]

Identifier: 220916137

GI number: 220916137

Start: 1147251

End: 1148525

Strand: Reverse

Name: cat2 [H]

Synonym: A2cp1_1024

Alternate gene names: 220916137

Gene position: 1148525-1147251 (Counterclockwise)

Preceding gene: 220916138

Following gene: 220916134

Centisome position: 22.84

GC content: 72.31

Gene sequence:

>1275_bases
ATGAGCCGCATCGTCTCCGCCGAGGAGGCCGTCTCCGTCGTCAAGTCCGGCCACCGGGTGTTCCTGCACAGCGTCGCCGC
GGCGCCGCGCCGGCTCATCGAGGCGCTCACCGCGCGGGCGCCCGAGCTGAGCGTCGTCGAGATCGTCTCGATCCACACCG
AGGGGGACGCGCCGTACGCCGCGCCCGAGATGGCCCGGCACTTCCGCGTGAACGCGCTGTTCGTCGGGCCGAACGTGCGC
AAGGCGATCGAGGAGGGGCGCGGCGACTACCTGCCGGTGTTCCTCTCCGAGGTGCCGCAGCTCTTCCGCTCCGGGATCCT
GCCGCTCGACGTGGCGCTGGTGCACGTCTCGCCGCCGGACCGCCACGGCTTCTGCTCGCTGGGCGTGTCGGTGGACGTCA
CCCGCGCCGCGGTGCAGACCGCCCGGACCGTGATCGCGCAGGTGAACCCGCGCATGCCGCGCACCCACGGCGACGGCCTC
ATCCACGTGGACGCGATCGACTACATGGTCGAGGTGGACGAGCCCATCCACGAGGCGCCGGTGCGGGCGCTCACCGACGT
GGAGCGCGCCATCGGCCGGCACTGCGCCGAGCTGGTGGACGACGGCGCCTGCCTGCAGCTCGGCATCGGGGCGATCCCGC
AGGCCACCCTGGCGTCGCTCGGCGACCACCACCGGCTCGGCATCCACACCGAGATGATCTCCGACGGCGTGGTGGACCTG
GTGGAGAAGGGCGTCATCACCGGCGAGCTGAAGCGCGTGCACCCGGGCAAGATCGTGGCCGGCTTCGCGCACGGCACCCG
CCGGCTCTACGACTTCCTGGACGACAACCCGCTCGTCGCGATGCTCGACATCGCCTACGTGAACGACACCGCGGTGATCC
GCCGCAACCCCAAGGTCACCGCCATCAACAGCGCCATCGAGGTGGACCTCACCGGCCAGGTGTGCGCCGACTCGGTGGGC
GAGCGGCAGGTGTCCGGCGTGGGCGGCCAGATGGACTTCATCCGCGGCGCGGCGCTCTCCGACGGCGGCAAGCCCATCAT
CGCGCTGCCCTCCACGAACGCGGCCGGCGAGTCGCGCATCGTCCCGGTGCTGCGCCCGGGCGCGGGCGTCGTCACCACCC
GCGCGCACGTCCACTTCGTGGTCACCGAGCACGGCATCGCCGACCTGTTCGGCAAGAACCTGCGCCAGCGCGCAGCCGCG
CTCATCGCGGTGGCGCACCCGAAGCATCGCGACGTCCTCACCGCCGAGGCGCGCCGCCGGTTCGGATCCTGGTAG

Upstream 100 bases:

>100_bases
GCGCGGCCGGCGGCGAGGTGCCCGGCACGGGTGCAAAGGCGCGCCCCCCGCTGGTACACTGGCGCGCCGCACCGCCCTGC
TCGAGAGGAGAGCCCTGCCG

Downstream 100 bases:

>100_bases
CCGGGCCGCCGCGCCGCGCTAGCCGGCGAGCCACTCGCGCACGCGCGCGTAGACGCCCGGGTCGCAGAGCAGGTCGAGGT
GGCCCACCCCGGGCGCGATG

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSRIVSAEEAVSVVKSGHRVFLHSVAAAPRRLIEALTARAPELSVVEIVSIHTEGDAPYAAPEMARHFRVNALFVGPNVR
KAIEEGRGDYLPVFLSEVPQLFRSGILPLDVALVHVSPPDRHGFCSLGVSVDVTRAAVQTARTVIAQVNPRMPRTHGDGL
IHVDAIDYMVEVDEPIHEAPVRALTDVERAIGRHCAELVDDGACLQLGIGAIPQATLASLGDHHRLGIHTEMISDGVVDL
VEKGVITGELKRVHPGKIVAGFAHGTRRLYDFLDDNPLVAMLDIAYVNDTAVIRRNPKVTAINSAIEVDLTGQVCADSVG
ERQVSGVGGQMDFIRGAALSDGGKPIIALPSTNAAGESRIVPVLRPGAGVVTTRAHVHFVVTEHGIADLFGKNLRQRAAA
LIAVAHPKHRDVLTAEARRRFGSW

Sequences:

>Translated_424_residues
MSRIVSAEEAVSVVKSGHRVFLHSVAAAPRRLIEALTARAPELSVVEIVSIHTEGDAPYAAPEMARHFRVNALFVGPNVR
KAIEEGRGDYLPVFLSEVPQLFRSGILPLDVALVHVSPPDRHGFCSLGVSVDVTRAAVQTARTVIAQVNPRMPRTHGDGL
IHVDAIDYMVEVDEPIHEAPVRALTDVERAIGRHCAELVDDGACLQLGIGAIPQATLASLGDHHRLGIHTEMISDGVVDL
VEKGVITGELKRVHPGKIVAGFAHGTRRLYDFLDDNPLVAMLDIAYVNDTAVIRRNPKVTAINSAIEVDLTGQVCADSVG
ERQVSGVGGQMDFIRGAALSDGGKPIIALPSTNAAGESRIVPVLRPGAGVVTTRAHVHFVVTEHGIADLFGKNLRQRAAA
LIAVAHPKHRDVLTAEARRRFGSW
>Mature_423_residues
SRIVSAEEAVSVVKSGHRVFLHSVAAAPRRLIEALTARAPELSVVEIVSIHTEGDAPYAAPEMARHFRVNALFVGPNVRK
AIEEGRGDYLPVFLSEVPQLFRSGILPLDVALVHVSPPDRHGFCSLGVSVDVTRAAVQTARTVIAQVNPRMPRTHGDGLI
HVDAIDYMVEVDEPIHEAPVRALTDVERAIGRHCAELVDDGACLQLGIGAIPQATLASLGDHHRLGIHTEMISDGVVDLV
EKGVITGELKRVHPGKIVAGFAHGTRRLYDFLDDNPLVAMLDIAYVNDTAVIRRNPKVTAINSAIEVDLTGQVCADSVGE
RQVSGVGGQMDFIRGAALSDGGKPIIALPSTNAAGESRIVPVLRPGAGVVTTRAHVHFVVTEHGIADLFGKNLRQRAAAL
IAVAHPKHRDVLTAEARRRFGSW

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=382, Percent_Identity=27.2251308900524, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32563853, Length=426, Percent_Identity=53.5211267605634, Blast_Score=451, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17538151, Length=426, Percent_Identity=46.0093896713615, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319456, Length=393, Percent_Identity=26.7175572519084, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21358615, Length=422, Percent_Identity=53.7914691943128, Blast_Score=465, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 45442; Mature: 45311

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIVSAEEAVSVVKSGHRVFLHSVAAAPRRLIEALTARAPELSVVEIVSIHTEGDAPYA
CCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCC
APEMARHFRVNALFVGPNVRKAIEEGRGDYLPVFLSEVPQLFRSGILPLDVALVHVSPPD
CHHHHHHEEEEEEEECCCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECCCC
RHGFCSLGVSVDVTRAAVQTARTVIAQVNPRMPRTHGDGLIHVDAIDYMVEVDEPIHEAP
CCCEEEECCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHEEEEEECCCCHHHHH
VRALTDVERAIGRHCAELVDDGACLQLGIGAIPQATLASLGDHHRLGIHTEMISDGVVDL
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCCCEEHHHHHCHHHHH
VEKGVITGELKRVHPGKIVAGFAHGTRRLYDFLDDNPLVAMLDIAYVNDTAVIRRNPKVT
HHCCCEECHHEECCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEECCCCEE
AINSAIEVDLTGQVCADSVGERQVSGVGGQMDFIRGAALSDGGKPIIALPSTNAAGESRI
EECCEEEEEECCHHHHHCCCCHHHHCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCEE
VPVLRPGAGVVTTRAHVHFVVTEHGIADLFGKNLRQRAAALIAVAHPKHRDVLTAEARRR
EEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEHHHHHH
FGSW
CCCC
>Mature Secondary Structure 
SRIVSAEEAVSVVKSGHRVFLHSVAAAPRRLIEALTARAPELSVVEIVSIHTEGDAPYA
CCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCC
APEMARHFRVNALFVGPNVRKAIEEGRGDYLPVFLSEVPQLFRSGILPLDVALVHVSPPD
CHHHHHHEEEEEEEECCCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECCCC
RHGFCSLGVSVDVTRAAVQTARTVIAQVNPRMPRTHGDGLIHVDAIDYMVEVDEPIHEAP
CCCEEEECCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHEEEEEECCCCHHHHH
VRALTDVERAIGRHCAELVDDGACLQLGIGAIPQATLASLGDHHRLGIHTEMISDGVVDL
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCCCEEHHHHHCHHHHH
VEKGVITGELKRVHPGKIVAGFAHGTRRLYDFLDDNPLVAMLDIAYVNDTAVIRRNPKVT
HHCCCEECHHEECCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEECCCCEE
AINSAIEVDLTGQVCADSVGERQVSGVGGQMDFIRGAALSDGGKPIIALPSTNAAGESRI
EECCEEEEEECCHHHHHCCCCHHHHCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCEE
VPVLRPGAGVVTTRAHVHFVVTEHGIADLFGKNLRQRAAALIAVAHPKHRDVLTAEARRR
EEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEHHHHHH
FGSW
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]