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The map label for this gene is ctaB [H]

Identifier: 220916065

GI number: 220916065

Start: 1072224

End: 1073120

Strand: Reverse

Name: ctaB [H]

Synonym: A2cp1_0952

Alternate gene names: 220916065

Gene position: 1073120-1072224 (Counterclockwise)

Preceding gene: 220916066

Following gene: 220916064

Centisome position: 21.34

GC content: 74.02

Gene sequence:

>897_bases
GTGCTCGCGGTGACCGTCGCCACCGCGCAGGCCCGCACCGCTCCGCAGCCGCTCGCCTACCTCAAGGACCTGGTCCTCCT
CTCGAAGCCGCGGCTCTCGGGCCTGGTGATGATCACCAGCGCCGGAGGCATGTGGCTCGCGCCCGGCCACATCGGCACCG
CCCGCGCCGTGCTGACCGTCCTCGCCACCGCGGTGGTGGTCGGCGCCGCGAACGCGCTCAACTGCTACCTCGAGCGCGAC
ATCGACGCGCGCATGCGGCGGACCCGCGATCGCCCGCTGCCCGCCGGCCGCGTCGATCCGTTCGTGGCGCTCGGGCTCGG
CATCGCCGCCCCCGCCTTCGCGATCCCGATCCTGTCGCTCGCCGCCAACGGGCTCACCGCCCTGCTCGCGCTGGTCGCGC
TCCTGACCTACGTGCTCGTGTACACGCCCATGAAGCAGCGCTCCGCGGCCGCGCTGTTCGTGGGCGCGGTCCCGGGCGCC
ATCCCGCCGCTCATGGGCTGGACGTCGGTGACCGGCGGGGTGGACGCCGGCGGGCTGGCGCTGTTCGGGCTCCTGTTCGC
GTGGCAGCTCCCGCACTTCCTCGCCATCTCGCTCTATCTCCGCGAGGACTACCAGCGCGGCGGGCTGCGCATGTTCGCCT
CGGTGCACGGCGAGCGCGCCACCCGGCTGTGGATGGCGCTGACCACGATCCTGCTCCTGCCCGCCTCGCTGGCGCTCGTC
CCGCTGGGCCTGGCCGGCACCGGCTACGCGGTGACCGCGGCGGTGCTGGGGATCGCGCTGTCCGCCTACGCCATCTCCGG
CATCGGCCGCGAGGGCGGGCGCTGGGCGCGCACGTTCTTCCTCGGCACCCTCGTCCACCTCACGGTGCTGTTCGTGGCCC
TCTTCCTCTCGCGCTGA

Upstream 100 bases:

>100_bases
CGCCGTCGCCCGTCGGGGCCATGGGGACCGCCCGCTGCCGCGCTCGACACCCGGGCGAGGCCCCTAACGCGACGTTGACC
CCCTGCCGAGCCCTGACTAA

Downstream 100 bases:

>100_bases
CGTGCCCGCCCCCGCCGCCATGCAGGCCGCTCCCGCGCGCCTCGCGCTGAAGGACGTCGCGTTCCGCCACGGCGCGCGCG
AGGTGCTGCGCGGCGTCTCG

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLAVTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITSAGGMWLAPGHIGTARAVLTVLATAVVVGAANALNCYLERD
IDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSLAANGLTALLALVALLTYVLVYTPMKQRSAAALFVGAVPGA
IPPLMGWTSVTGGVDAGGLALFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALV
PLGLAGTGYAVTAAVLGIALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR

Sequences:

>Translated_298_residues
MLAVTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITSAGGMWLAPGHIGTARAVLTVLATAVVVGAANALNCYLERD
IDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSLAANGLTALLALVALLTYVLVYTPMKQRSAAALFVGAVPGA
IPPLMGWTSVTGGVDAGGLALFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALV
PLGLAGTGYAVTAAVLGIALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR
>Mature_298_residues
MLAVTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITSAGGMWLAPGHIGTARAVLTVLATAVVVGAANALNCYLERD
IDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSLAANGLTALLALVALLTYVLVYTPMKQRSAAALFVGAVPGA
IPPLMGWTSVTGGVDAGGLALFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALV
PLGLAGTGYAVTAAVLGIALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=193, Percent_Identity=44.0414507772021, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1786631, Length=285, Percent_Identity=31.9298245614035, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71998235, Length=201, Percent_Identity=37.8109452736318, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325085, Length=240, Percent_Identity=30, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19921064, Length=282, Percent_Identity=35.1063829787234, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31210; Mature: 31210

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITSAGGMWLAPGHIGTARAVLTV
CEEEEEECHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHH
LATAVVVGAANALNCYLERDIDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSL
HHHHHHHHCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AANGLTALLALVALLTYVLVYTPMKQRSAAALFVGAVPGAIPPLMGWTSVTGGVDAGGLA
HHCHHHHHHHHHHHHHHHHHHCCCHHHCHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
LFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
PLGLAGTGYAVTAAVLGIALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAVTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITSAGGMWLAPGHIGTARAVLTV
CEEEEEECHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHH
LATAVVVGAANALNCYLERDIDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSL
HHHHHHHHCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AANGLTALLALVALLTYVLVYTPMKQRSAAALFVGAVPGAIPPLMGWTSVTGGVDAGGLA
HHCHHHHHHHHHHHHHHHHHHCCCHHHCHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
LFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
PLGLAGTGYAVTAAVLGIALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA