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The map label for this gene is kdpE [H]

Identifier: 220916055

GI number: 220916055

Start: 1062152

End: 1062847

Strand: Reverse

Name: kdpE [H]

Synonym: A2cp1_0942

Alternate gene names: 220916055

Gene position: 1062847-1062152 (Counterclockwise)

Preceding gene: 220916056

Following gene: 220916050

Centisome position: 21.13

GC content: 75.57

Gene sequence:

>696_bases
GTGACCGGCGGCGGCCCGCTCGTGCTCGTCGTCGAGGACGAGGCGCCGGTACGCCGCTTCCTGCGCGCCGCGCTGGCCGC
GCACGGCTACCGGATCGAGGAGGCCGGCACGGTCGCCGAGGCGGAGCAGCTCGCGCCCGGCCACAACCCGGACGTCTTCC
TCCTCGACCTCGGGCTCCCGGACGGCGACGGGATCGACCTCGCCCGGCGGCTCCGCGAGTGGACGCGCGCGCCGATCATC
GTGCTGTCGGCGCGCGGCCGCGAGGAGGACAAGGTGACCGCCCTCGACGCCGGGGCCGACGACTACCTGACGAAGCCGTT
CGGAGTGAACGAGCTCCTGGCGCGCGTCCGGGTGGCGCTCCGGCACGCCCAGGCGCCGCCGGATGGGCCTCCGGTGGTCG
AGGTCGGGCCGCTCCGCATCGACCTCGCCCGCCGCGAGATCACGCGGAGCGGCGCCGAGGTGCGGCTCACGCCCACCGAG
TACCGGGTCCTCGCGATGCTCGCGCGCAACGCGGGCAAGGTGCTGACCCACCGCCAGATCCTCCGCGAGGTGTGGGGCCC
GAACGCGACCGAGGCGCACTACGTCCGCGTCCAGGTGGCCGAGCTGCGCAAGAAGCTCGAGGACGAGCCGGCGCGGCCGC
GGCTGCTGATGACCGAGCCCGGCGTCGGGTACCGCCTGCGCGACCGCGTCGACTGA

Upstream 100 bases:

>100_bases
GCGGCGGGGCGGTGTTCCGCCTGACCCTGCCCGTCGGGGCGCCTCCTGCCGCACCGCCGGAGCCCCCCGGCGAGCGCCTG
CCGGAGCGAGGGGGCGGGCC

Downstream 100 bases:

>100_bases
CGGACGCGAGGCCGGCTCAGCCGCCCCACAGCCCCCAGCGTCCGGCGCCCAGCACCGCGGCGGCGATGGCGGCGTTCGCG
ACCGCGTGCGCCAGCACGGC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTGGGPLVLVVEDEAPVRRFLRAALAAHGYRIEEAGTVAEAEQLAPGHNPDVFLLDLGLPDGDGIDLARRLREWTRAPII
VLSARGREEDKVTALDAGADDYLTKPFGVNELLARVRVALRHAQAPPDGPPVVEVGPLRIDLARREITRSGAEVRLTPTE
YRVLAMLARNAGKVLTHRQILREVWGPNATEAHYVRVQVAELRKKLEDEPARPRLLMTEPGVGYRLRDRVD

Sequences:

>Translated_231_residues
MTGGGPLVLVVEDEAPVRRFLRAALAAHGYRIEEAGTVAEAEQLAPGHNPDVFLLDLGLPDGDGIDLARRLREWTRAPII
VLSARGREEDKVTALDAGADDYLTKPFGVNELLARVRVALRHAQAPPDGPPVVEVGPLRIDLARREITRSGAEVRLTPTE
YRVLAMLARNAGKVLTHRQILREVWGPNATEAHYVRVQVAELRKKLEDEPARPRLLMTEPGVGYRLRDRVD
>Mature_230_residues
TGGGPLVLVVEDEAPVRRFLRAALAAHGYRIEEAGTVAEAEQLAPGHNPDVFLLDLGLPDGDGIDLARRLREWTRAPIIV
LSARGREEDKVTALDAGADDYLTKPFGVNELLARVRVALRHAQAPPDGPPVVEVGPLRIDLARREITRSGAEVRLTPTEY
RVLAMLARNAGKVLTHRQILREVWGPNATEAHYVRVQVAELRKKLEDEPARPRLLMTEPGVGYRLRDRVD

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=56.3636363636364, Blast_Score=244, Evalue=2e-66,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=37.2727272727273, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=38.0090497737557, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=36.1233480176211, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=32.5892857142857, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=36.4864864864865, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=32.3008849557522, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=33.4821428571429, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.4324324324324, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.646017699115, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.8701298701299, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=39.1304347826087, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25541; Mature: 25409

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGGPLVLVVEDEAPVRRFLRAALAAHGYRIEEAGTVAEAEQLAPGHNPDVFLLDLGLP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCEEEEECCCC
DGDGIDLARRLREWTRAPIIVLSARGREEDKVTALDAGADDYLTKPFGVNELLARVRVAL
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHH
RHAQAPPDGPPVVEVGPLRIDLARREITRSGAEVRLTPTEYRVLAMLARNAGKVLTHRQI
HHCCCCCCCCCEEEECCEEEHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHH
LREVWGPNATEAHYVRVQVAELRKKLEDEPARPRLLMTEPGVGYRLRDRVD
HHHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCC
>Mature Secondary Structure 
TGGGPLVLVVEDEAPVRRFLRAALAAHGYRIEEAGTVAEAEQLAPGHNPDVFLLDLGLP
CCCCCEEEEECCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCEEEEECCCC
DGDGIDLARRLREWTRAPIIVLSARGREEDKVTALDAGADDYLTKPFGVNELLARVRVAL
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHH
RHAQAPPDGPPVVEVGPLRIDLARREITRSGAEVRLTPTEYRVLAMLARNAGKVLTHRQI
HHCCCCCCCCCEEEECCEEEHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHH
LREVWGPNATEAHYVRVQVAELRKKLEDEPARPRLLMTEPGVGYRLRDRVD
HHHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]