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The map label for this gene is phoP [H]

Identifier: 220916035

GI number: 220916035

Start: 1042274

End: 1043653

Strand: Direct

Name: phoP [H]

Synonym: A2cp1_0922

Alternate gene names: 220916035

Gene position: 1042274-1043653 (Clockwise)

Preceding gene: 220916034

Following gene: 220916038

Centisome position: 20.72

GC content: 78.12

Gene sequence:

>1380_bases
GTGGTTCCGCACATCGGGGAGCTGCTGGTCCGGCGCGGCGTGGCGACCGCCGCGCAGGTGGAGTCCGCGCTGCACGACCC
GCGCGATCGGCCGCTGCCGCTCGCGTCGAGGCTGCTGGAGGCGGGCGTGGACGAGGGCGCGCTGGCCGCCGCGCTGGCGG
AGCGCTTCGGCATGCCCGGGGTGGACCTGTCGCGCACCACCATCGATCTCGACGCGCTGGAGGCCGTTCCGCGGACGGTG
GCCGAGCAGGACCTGATCCTGCCGCTCTCGCTGGAGGGCGGGCGCATCCACCTCGCCATGGCGCGCCCGCTCGACGACCG
CGTCGTCGCCGAGCTGCGCTTCGTGACCGGGCGCGAGGTGTCGGTGTACGCGGCGATCCGCTCGGCGCTCGATCGCGCCA
TCGAGGGCGCCTACGAGGCGCGCGCGCGGGGCGAGCGGTCCTGGCGCGGCGCGAACGCCGGGCCGCTGCCGGAGCTGGGC
GCGGCGTTCCCGGAGGGCGAGGCCGCCGACGAGCCGCTGGACGTGGTGGAGGTGCTCGAGGCCGACCTCCTGCCCGACGA
GCCGGACGTGGGCGTGCGGATCGAGGTGGGCGCGCCGGAGCCGCTGCCGGTGCGCGCGGACGCCCGGCCGCTGGCGCTGG
TGGTGGACGACGAGCCGGAGATCCGGCAGCTGGTGCAGCGCACGCTCGAGTCCAGGGGCTGGGCCGTGGAGCTGGCCACC
GACGGGGAGGAGGCGCTGGCCCGTGCCGACGCGCTGCTCCCGGACGTCGTGCTCCTCGACGCGATGCTGCCCCGGCTGCA
CGGGTTCGAGGCGTGCCGCCGGCTCCGCTCATCGCCGCGCACCCGCAACGTGCCGGTGGTGATGATGACCGCCATCTACC
GCGGCTGGCGCTTCGCCGAGGACGCGCGCGAGAACTACGGCGCGGTGGACTACGTGGAGAAGCCGTTCCGGCTCGACGAC
CTGGCCCGGCGCGTGGCGGCCGCGCGCGAGGCGAGCGCGTCCCGGCCGCTCGCGCCCGCGCCCGAGGCGGACGCGCGCGT
GGCCCGCGGGCGCGCGCTCCTCGACGAGGGCCGCGCGGTCGAGGCCGCAGCGCTCCTCGCCGACGCGGCCCACGCCGACC
CGCTCGGCGCCGAGGCGCACCTCCAGCTCGGGCGGGCGCTCGCCGCGACCGGCGACGCCTTCGGCGCGATGACCGCCCTC
GAGCGCGCCGTCGAGCTGCGTCCGGGCAACCTGCCGGGGCTGCGCGCCCTGGCGCGGCTGTACGAGGAGAAGGGCTTCCG
CCGCAACGCGGCCGGGACGCTGGAGCGCGCCGTCGCCGCGGCGCCGGAGGGGGCGGAGCGCGCCGCCATCCGCGAGGACC
TGCTGCGCCTGCTCGCCTGA

Upstream 100 bases:

>100_bases
ACGACGGGGTGTCGAGGGTCGCGGCGTCGTGGGACGCCGCCGCTCGCCGCCGCCGCCTAGAATCCGGCTCGACCCGCCCT
GCGGGTCGGGGGGAGGGGGC

Downstream 100 bases:

>100_bases
GCGCCCGGCCGCCGCGCCGCCCCGCGCGCGAGGCGATCACCCGCCGGCCGTCCCAGGCGTCTTCCAGCTCCGGATCAGGA
ACTCCTCCTCGAGCGGCGTC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MVPHIGELLVRRGVATAAQVESALHDPRDRPLPLASRLLEAGVDEGALAAALAERFGMPGVDLSRTTIDLDALEAVPRTV
AEQDLILPLSLEGGRIHLAMARPLDDRVVAELRFVTGREVSVYAAIRSALDRAIEGAYEARARGERSWRGANAGPLPELG
AAFPEGEAADEPLDVVEVLEADLLPDEPDVGVRIEVGAPEPLPVRADARPLALVVDDEPEIRQLVQRTLESRGWAVELAT
DGEEALARADALLPDVVLLDAMLPRLHGFEACRRLRSSPRTRNVPVVMMTAIYRGWRFAEDARENYGAVDYVEKPFRLDD
LARRVAAAREASASRPLAPAPEADARVARGRALLDEGRAVEAAALLADAAHADPLGAEAHLQLGRALAATGDAFGAMTAL
ERAVELRPGNLPGLRALARLYEEKGFRRNAAGTLERAVAAAPEGAERAAIREDLLRLLA

Sequences:

>Translated_459_residues
MVPHIGELLVRRGVATAAQVESALHDPRDRPLPLASRLLEAGVDEGALAAALAERFGMPGVDLSRTTIDLDALEAVPRTV
AEQDLILPLSLEGGRIHLAMARPLDDRVVAELRFVTGREVSVYAAIRSALDRAIEGAYEARARGERSWRGANAGPLPELG
AAFPEGEAADEPLDVVEVLEADLLPDEPDVGVRIEVGAPEPLPVRADARPLALVVDDEPEIRQLVQRTLESRGWAVELAT
DGEEALARADALLPDVVLLDAMLPRLHGFEACRRLRSSPRTRNVPVVMMTAIYRGWRFAEDARENYGAVDYVEKPFRLDD
LARRVAAAREASASRPLAPAPEADARVARGRALLDEGRAVEAAALLADAAHADPLGAEAHLQLGRALAATGDAFGAMTAL
ERAVELRPGNLPGLRALARLYEEKGFRRNAAGTLERAVAAAPEGAERAAIREDLLRLLA
>Mature_459_residues
MVPHIGELLVRRGVATAAQVESALHDPRDRPLPLASRLLEAGVDEGALAAALAERFGMPGVDLSRTTIDLDALEAVPRTV
AEQDLILPLSLEGGRIHLAMARPLDDRVVAELRFVTGREVSVYAAIRSALDRAIEGAYEARARGERSWRGANAGPLPELG
AAFPEGEAADEPLDVVEVLEADLLPDEPDVGVRIEVGAPEPLPVRADARPLALVVDDEPEIRQLVQRTLESRGWAVELAT
DGEEALARADALLPDVVLLDAMLPRLHGFEACRRLRSSPRTRNVPVVMMTAIYRGWRFAEDARENYGAVDYVEKPFRLDD
LARRVAAAREASASRPLAPAPEADARVARGRALLDEGRAVEAAALLADAAHADPLGAEAHLQLGRALAATGDAFGAMTAL
ERAVELRPGNLPGLRALARLYEEKGFRRNAAGTLERAVAAAPEGAERAAIREDLLRLLA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=37.8151260504202, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788394, Length=160, Percent_Identity=32.5, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=38.5321100917431, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=218, Percent_Identity=30.7339449541284, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 49252; Mature: 49252

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPHIGELLVRRGVATAAQVESALHDPRDRPLPLASRLLEAGVDEGALAAALAERFGMPG
CCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
VDLSRTTIDLDALEAVPRTVAEQDLILPLSLEGGRIHLAMARPLDDRVVAELRFVTGREV
CCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCH
SVYAAIRSALDRAIEGAYEARARGERSWRGANAGPLPELGAAFPEGEAADEPLDVVEVLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHH
ADLLPDEPDVGVRIEVGAPEPLPVRADARPLALVVDDEPEIRQLVQRTLESRGWAVELAT
HHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEC
DGEEALARADALLPDVVLLDAMLPRLHGFEACRRLRSSPRTRNVPVVMMTAIYRGWRFAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHH
DARENYGAVDYVEKPFRLDDLARRVAAAREASASRPLAPAPEADARVARGRALLDEGRAV
HHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHCCCHH
EAAALLADAAHADPLGAEAHLQLGRALAATGDAFGAMTALERAVELRPGNLPGLRALARL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YEEKGFRRNAAGTLERAVAAAPEGAERAAIREDLLRLLA
HHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVPHIGELLVRRGVATAAQVESALHDPRDRPLPLASRLLEAGVDEGALAAALAERFGMPG
CCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
VDLSRTTIDLDALEAVPRTVAEQDLILPLSLEGGRIHLAMARPLDDRVVAELRFVTGREV
CCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCH
SVYAAIRSALDRAIEGAYEARARGERSWRGANAGPLPELGAAFPEGEAADEPLDVVEVLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHH
ADLLPDEPDVGVRIEVGAPEPLPVRADARPLALVVDDEPEIRQLVQRTLESRGWAVELAT
HHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEC
DGEEALARADALLPDVVLLDAMLPRLHGFEACRRLRSSPRTRNVPVVMMTAIYRGWRFAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHH
DARENYGAVDYVEKPFRLDDLARRVAAAREASASRPLAPAPEADARVARGRALLDEGRAV
HHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHCCCHH
EAAALLADAAHADPLGAEAHLQLGRALAATGDAFGAMTALERAVELRPGNLPGLRALARL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YEEKGFRRNAAGTLERAVAAAPEGAERAAIREDLLRLLA
HHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]