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The map label for this gene is degP [H]

Identifier: 220916019

GI number: 220916019

Start: 1024656

End: 1025594

Strand: Reverse

Name: degP [H]

Synonym: A2cp1_0905

Alternate gene names: 220916019

Gene position: 1025594-1024656 (Counterclockwise)

Preceding gene: 220916023

Following gene: 220916018

Centisome position: 20.39

GC content: 80.72

Gene sequence:

>939_bases
ATGACCTCCGCGCCTCCCGTCAGCCCTGCCCTGCCGTCCGACCTGCTCGCCCAGCTCTCCGCGCGCCTCGCCGCCCTCAC
CGCGTCCGCCGCCGCGCACGTCGTGCGGGTCGAGGGACGGCGCCACGCGCCCGCGTCGGGCGTGGTGTGGTCGGCCGACG
GCGTGATCGTGACCGCGCACCACGCGCTCGAGCGCGACGAGGGCGTGACGGTCGGCCTGCCCTCGGGCGACGAGGTCGCG
GCGGAGGTGATCGGCCGCGACCCCAGCACCGACCTCGCCGCGCTGCGGGTGCGCGCGCCGGGGCTCGCGCCGCCGGACTG
GGCGGACGCGGCCGGCGCCGCCGGGGGGCAGCTCACGCTGGTCGTCACGCGGCCGGGGCGAGGGCCGCGCGCGGAGCTGG
GCCTGCTGGCGCGCGCCGGCGACGCGTTCCGCGCGCCCATGGGTGGGCGCGTCGACCGCTACCTGGAGCTGGGGATCCCC
CGGCACCCGGGGCTCTCCGGCGGCCTGGTGCTCGGCGCGGATGGCCTCGCGCTCGGCCTCGCGGCGGCGGGGCTGGTGCG
GGGCGCGGCGCTGGCGGTGCCCGCCGCCACGCTCGCGCGGGTGGTGACCTCGCTCCTCTCGCACGGCGAGGTGCGCCGCG
GCTACCTCGGCCTCGCCACGCAGCCGGTCCCGCTCCCGCCGGCGCTGCGCGCGCGCACCGGCGAGGAGCTGGCGCTGCTC
GTCGCGCGCGTCGAGCCGGGCAGCCCGGCGGACCGCGCGGGCGTGCTGCTCGGCGACGCCATCCTCTCGGTGGGCGGCGA
GGCGCTGCAGGATCCGGGGGAGCTGCTGGCCCTGCTCTCGGAGGACCGGATCGGCCAGGCGGTGACGCTGCGCGTGCTGC
GCGCGGGCGAGGTGCGCGACGTCGCGGTCACCGTGGGCGCGCGCGGGAGGCGGGCGTGA

Upstream 100 bases:

>100_bases
GCACCTCCCCGCGCGCCGGGCGCGACCTGCCCATCCGACCAGGCCGCGCCCTGGCCCTCCCGCCGATGTGCGCGGCGAGC
GGACCGCCTAGCTTCCCGCC

Downstream 100 bases:

>100_bases
CCGGGCTGCAGGCGCTCTCGCGCGACGTCGCCGACCTCGTGGCCCGCGCCGCCCCGGCGGTGGTGGGCGTGGAGCAGGGC
GGCGGCCAGGGCTCCGGCGT

Product: PDZ/DHR/GLGF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTSAPPVSPALPSDLLAQLSARLAALTASAAAHVVRVEGRRHAPASGVVWSADGVIVTAHHALERDEGVTVGLPSGDEVA
AEVIGRDPSTDLAALRVRAPGLAPPDWADAAGAAGGQLTLVVTRPGRGPRAELGLLARAGDAFRAPMGGRVDRYLELGIP
RHPGLSGGLVLGADGLALGLAAAGLVRGAALAVPAATLARVVTSLLSHGEVRRGYLGLATQPVPLPPALRARTGEELALL
VARVEPGSPADRAGVLLGDAILSVGGEALQDPGELLALLSEDRIGQAVTLRVLRAGEVRDVAVTVGARGRRA

Sequences:

>Translated_312_residues
MTSAPPVSPALPSDLLAQLSARLAALTASAAAHVVRVEGRRHAPASGVVWSADGVIVTAHHALERDEGVTVGLPSGDEVA
AEVIGRDPSTDLAALRVRAPGLAPPDWADAAGAAGGQLTLVVTRPGRGPRAELGLLARAGDAFRAPMGGRVDRYLELGIP
RHPGLSGGLVLGADGLALGLAAAGLVRGAALAVPAATLARVVTSLLSHGEVRRGYLGLATQPVPLPPALRARTGEELALL
VARVEPGSPADRAGVLLGDAILSVGGEALQDPGELLALLSEDRIGQAVTLRVLRAGEVRDVAVTVGARGRRA
>Mature_311_residues
TSAPPVSPALPSDLLAQLSARLAALTASAAAHVVRVEGRRHAPASGVVWSADGVIVTAHHALERDEGVTVGLPSGDEVAA
EVIGRDPSTDLAALRVRAPGLAPPDWADAAGAAGGQLTLVVTRPGRGPRAELGLLARAGDAFRAPMGGRVDRYLELGIPR
HPGLSGGLVLGADGLALGLAAAGLVRGAALAVPAATLARVVTSLLSHGEVRRGYLGLATQPVPLPPALRARTGEELALLV
ARVEPGSPADRAGVLLGDAILSVGGEALQDPGELLALLSEDRIGQAVTLRVLRAGEVRDVAVTVGARGRRA

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=271, Percent_Identity=25.830258302583, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789629, Length=268, Percent_Identity=27.9850746268657, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=25.3571428571429, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 31441; Mature: 31309

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPPVSPALPSDLLAQLSARLAALTASAAAHVVRVEGRRHAPASGVVWSADGVIVTAH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEECCCEEEEEE
HALERDEGVTVGLPSGDEVAAEVIGRDPSTDLAALRVRAPGLAPPDWADAAGAAGGQLTL
HHHHCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHCCCCCCEEEE
VVTRPGRGPRAELGLLARAGDAFRAPMGGRVDRYLELGIPRHPGLSGGLVLGADGLALGL
EEECCCCCCHHHHHHHEECCCHHCCCCCCCHHHHHEECCCCCCCCCCCEEECCCHHHHHH
AAAGLVRGAALAVPAATLARVVTSLLSHGEVRRGYLGLATQPVPLPPALRARTGEELALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEECCCCCCCCCCHHHHCCCCCCEEEE
VARVEPGSPADRAGVLLGDAILSVGGEALQDPGELLALLSEDRIGQAVTLRVLRAGEVRD
EEECCCCCCCHHCCHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEEEEHHCCCCEE
VAVTVGARGRRA
EEEEECCCCCCC
>Mature Secondary Structure 
TSAPPVSPALPSDLLAQLSARLAALTASAAAHVVRVEGRRHAPASGVVWSADGVIVTAH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEECCCEEEEEE
HALERDEGVTVGLPSGDEVAAEVIGRDPSTDLAALRVRAPGLAPPDWADAAGAAGGQLTL
HHHHCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHCCCCCCEEEE
VVTRPGRGPRAELGLLARAGDAFRAPMGGRVDRYLELGIPRHPGLSGGLVLGADGLALGL
EEECCCCCCHHHHHHHEECCCHHCCCCCCCHHHHHEECCCCCCCCCCCEEECCCHHHHHH
AAAGLVRGAALAVPAATLARVVTSLLSHGEVRRGYLGLATQPVPLPPALRARTGEELALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEECCCCCCCCCCHHHHCCCCCCEEEE
VARVEPGSPADRAGVLLGDAILSVGGEALQDPGELLALLSEDRIGQAVTLRVLRAGEVRD
EEECCCCCCCHHCCHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEEEEHHCCCCEE
VAVTVGARGRRA
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]